MCH_HUMAN
Evidence for PS localization
Functions
MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
No data found.
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in MCH_HUMAN |
|---|---|---|---|---|
| GO:0005179 | hormone activity | 40.0000 | 5 | yes |
| GO:0048018 | receptor ligand activity | 40.0000 | 4 | yes |
| GO:0004842 | ubiquitin-protein transferase activity | 40.0000 | 4 | no |
| GO:0016755 | aminoacyltransferase activity | 40.0000 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MCH_HUMAN |
|---|---|---|---|---|
| GO:0010646 | regulation of cell communication | 60.0000 | 4 | no |
| GO:0099536 | synaptic signaling | 40.0000 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 40.0000 | 4 | no |
| GO:0016567 | protein ubiquitination | 40.0000 | 8 | no |
| GO:0032446 | protein modification by small protein conjugation | 40.0000 | 7 | no |
| GO:0036211 | protein modification process | 40.0000 | 4 | no |
| GO:0043412 | macromolecule modification | 40.0000 | 4 | no |
| GO:0043687 | post-translational protein modification | 40.0000 | 5 | no |
| GO:0048522 | positive regulation of cellular process | 40.0000 | 4 | no |
| GO:0070647 | protein modification by small protein conjugation or removal | 40.0000 | 6 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NPY_HUMAN | [view interactions] | Low throughput | no | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| ASF1A_HUMAN | [view interactions] | High throughput | no | no |
| SULF1_HUMAN | [view interactions] | High throughput | no | no |
| TPST1_HUMAN | [view interactions] | High throughput | no | yes |
| VWDE_HUMAN | [view interactions] | High throughput | no | no |
| MIB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| CDN2D_HUMAN | [view interactions] | High throughput | no | no |
| ANT3_HUMAN | [view interactions] | High throughput | no | no |
| MAEA_HUMAN | [view interactions] | High throughput | no | yes |
| B4GT5_HUMAN | [view interactions] | High throughput | no | no |
| ITIH2_HUMAN | [view interactions] | High throughput | no | no |
| NPW_HUMAN | [view interactions] | High throughput | no | no |
| TMM59_HUMAN | [view interactions] | High throughput | no | yes |
| VGF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBPE_HUMAN | [view interactions] | High throughput | no | yes |
| NEC1_HUMAN | [view interactions] | High throughput | no | yes |
| NEC2_HUMAN | [view interactions] | High throughput | no | no |