Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

VGF_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Has bactericidal activity against M. luteus, and antifungal activity against P. Pastoris. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in VGF_HUMAN
GO:0000166 nucleotide binding 50.0000 4 no
GO:0017076 purine nucleotide binding 50.0000 5 no
GO:0032555 purine ribonucleotide binding 50.0000 4 no
GO:0043168 anion binding 50.0000 4 no
GO:0030554 adenyl nucleotide binding 37.5000 6 no
GO:0032559 adenyl ribonucleotide binding 37.5000 5 no
GO:0035639 purine ribonucleoside triphosphate binding 37.5000 4 no
GO:0005179 hormone activity 25.0000 5 yes
GO:0048018 receptor ligand activity 25.0000 4 yes
GO:0001664 G protein-coupled receptor binding 25.0000 4 no
GO:0043169 cation binding 25.0000 4 no
GO:0046872 metal ion binding 25.0000 5 no
GO:0005524 ATP binding 25.0000 5 no
GO:0016301 kinase activity 25.0000 4 no
GO:0016773 phosphotransferase activity, alcohol group as acceptor 25.0000 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in VGF_HUMAN
GO:0010646 regulation of cell communication 75.0000 4 yes
GO:0050804 modulation of chemical synaptic transmission 62.5000 5 yes
GO:0099177 regulation of trans-synaptic signaling 62.5000 4 yes
GO:0009889 regulation of biosynthetic process 62.5000 4 no
GO:0009966 regulation of signal transduction 62.5000 4 no
GO:0010468 regulation of gene expression 62.5000 6 no
GO:0010556 regulation of macromolecule biosynthetic process 62.5000 5 no
GO:0031323 regulation of cellular metabolic process 62.5000 4 no
GO:0031326 regulation of cellular biosynthetic process 62.5000 5 no
GO:0048522 positive regulation of cellular process 62.5000 4 no
GO:0060255 regulation of macromolecule metabolic process 62.5000 4 no
GO:0008104 protein localization 50.0000 4 yes
GO:0014070 response to organic cyclic compound 50.0000 4 yes
GO:0009891 positive regulation of biosynthetic process 50.0000 5 no
GO:0009893 positive regulation of metabolic process 50.0000 4 no
GO:0009967 positive regulation of signal transduction 50.0000 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 50.0000 6 no
GO:0010604 positive regulation of macromolecule metabolic process 50.0000 5 no
GO:0010647 positive regulation of cell communication 50.0000 5 no
GO:0023056 positive regulation of signaling 50.0000 4 no
GO:0031325 positive regulation of cellular metabolic process 50.0000 5 no
GO:0031328 positive regulation of cellular biosynthetic process 50.0000 6 no
GO:0048584 positive regulation of response to stimulus 50.0000 4 no
GO:0051094 positive regulation of developmental process 50.0000 4 no
GO:0051128 regulation of cellular component organization 50.0000 4 no
GO:0080090 regulation of primary metabolic process 50.0000 4 no
GO:1902533 positive regulation of intracellular signal transduction 37.5000 6 no
GO:2001141 regulation of RNA biosynthetic process 37.5000 6 no
GO:0042127 regulation of cell population proliferation 37.5000 4 no
GO:0010243 response to organonitrogen compound 37.5000 4 yes
GO:0071702 organic substance transport 37.5000 4 yes
GO:0071705 nitrogen compound transport 37.5000 4 yes
GO:0099536 synaptic signaling 37.5000 4 yes
GO:0006355 regulation of DNA-templated transcription 37.5000 7 no
GO:0009894 regulation of catabolic process 37.5000 4 no
GO:0010628 positive regulation of gene expression 37.5000 7 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 37.5000 5 no
GO:0022607 cellular component assembly 37.5000 4 no
GO:0036211 protein modification process 37.5000 4 no
GO:0042981 regulation of apoptotic process 37.5000 5 no
GO:0043067 regulation of programmed cell death 37.5000 4 no
GO:0043412 macromolecule modification 37.5000 4 no
GO:0043933 protein-containing complex organization 37.5000 4 no
GO:0048523 negative regulation of cellular process 37.5000 4 no
GO:0051049 regulation of transport 37.5000 4 no
GO:0051130 positive regulation of cellular component organization 37.5000 5 no
GO:0051252 regulation of RNA metabolic process 37.5000 5 no
GO:0060627 regulation of vesicle-mediated transport 37.5000 4 no
GO:0065003 protein-containing complex assembly 37.5000 5 no
GO:0071310 cellular response to organic substance 37.5000 4 no
GO:1901701 cellular response to oxygen-containing compound 37.5000 4 no
GO:1902531 regulation of intracellular signal transduction 37.5000 5 no
GO:1902532 negative regulation of intracellular signal transduction 25.0000 6 no
GO:1902680 positive regulation of RNA biosynthetic process 25.0000 7 no
GO:1903530 regulation of secretion by cell 25.0000 4 no
GO:1903859 regulation of dendrite extension 25.0000 5 no
GO:1903861 positive regulation of dendrite extension 25.0000 6 no
GO:0048666 neuron development 25.0000 4 no
GO:0007600 sensory perception 25.0000 4 no
GO:0051240 positive regulation of multicellular organismal process 25.0000 4 no
GO:0000165 MAPK cascade 25.0000 5 no
GO:0006468 protein phosphorylation 25.0000 5 no
GO:0006796 phosphate-containing compound metabolic process 25.0000 4 no
GO:0006915 apoptotic process 25.0000 4 no
GO:0007167 enzyme-linked receptor protein signaling pathway 25.0000 4 no
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway 25.0000 5 no
GO:0008284 positive regulation of cell population proliferation 25.0000 5 no
GO:0009059 macromolecule biosynthetic process 25.0000 4 no
GO:0016310 phosphorylation 25.0000 5 no
GO:0018108 peptidyl-tyrosine phosphorylation 25.0000 6 no
GO:0018193 peptidyl-amino acid modification 25.0000 5 no
GO:0018212 peptidyl-tyrosine modification 25.0000 6 no
GO:0021782 glial cell development 25.0000 4 no
GO:0038083 peptidyl-tyrosine autophosphorylation 25.0000 7 no
GO:0046777 protein autophosphorylation 25.0000 6 no
GO:0141124 intracellular signaling cassette 25.0000 4 no
GO:0045595 regulation of cell differentiation 25.0000 4 no
GO:0014074 response to purine-containing compound 25.0000 5 yes
GO:0015031 protein transport 25.0000 4 yes
GO:0023061 signal release 25.0000 4 yes
GO:0046683 response to organophosphorus 25.0000 4 yes
GO:0046903 secretion 25.0000 4 yes
GO:0048168 regulation of neuronal synaptic plasticity 25.0000 4 yes
GO:0051591 response to cAMP 25.0000 4 yes
GO:0001558 regulation of cell growth 25.0000 4 no
GO:0001932 regulation of protein phosphorylation 25.0000 7 no
GO:0006357 regulation of transcription by RNA polymerase II 25.0000 8 no
GO:0006996 organelle organization 25.0000 4 no
GO:0007268 chemical synaptic transmission 25.0000 7 no
GO:0007612 learning 25.0000 4 no
GO:0009892 negative regulation of metabolic process 25.0000 4 no
GO:0009896 positive regulation of catabolic process 25.0000 5 no
GO:0009968 negative regulation of signal transduction 25.0000 5 no
GO:0010038 response to metal ion 25.0000 4 no
GO:0010506 regulation of autophagy 25.0000 6 no
GO:0010508 positive regulation of autophagy 25.0000 7 no
GO:0010638 positive regulation of organelle organization 25.0000 6 no
GO:0010648 negative regulation of cell communication 25.0000 5 no
GO:0016236 macroautophagy 25.0000 4 no
GO:0017157 regulation of exocytosis 25.0000 5 no
GO:0019220 regulation of phosphate metabolic process 25.0000 6 no
GO:0022603 regulation of anatomical structure morphogenesis 25.0000 4 no
GO:0022604 regulation of cell morphogenesis 25.0000 5 no
GO:0023057 negative regulation of signaling 25.0000 4 no
GO:0030307 positive regulation of cell growth 25.0000 5 no
GO:0031329 regulation of cellular catabolic process 25.0000 5 no
GO:0031331 positive regulation of cellular catabolic process 25.0000 6 no
GO:0031399 regulation of protein modification process 25.0000 6 no
GO:0031401 positive regulation of protein modification process 25.0000 7 no
GO:0032386 regulation of intracellular transport 25.0000 5 no
GO:0033043 regulation of organelle organization 25.0000 5 no
GO:0034599 cellular response to oxidative stress 25.0000 4 no
GO:0042325 regulation of phosphorylation 25.0000 7 no
GO:0043066 negative regulation of apoptotic process 25.0000 6 no
GO:0043069 negative regulation of programmed cell death 25.0000 5 no
GO:0043408 regulation of MAPK cascade 25.0000 6 no
GO:0043523 regulation of neuron apoptotic process 25.0000 6 no
GO:0043524 negative regulation of neuron apoptotic process 25.0000 7 no
GO:0045893 positive regulation of DNA-templated transcription 25.0000 8 no
GO:0045927 positive regulation of growth 25.0000 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 25.0000 5 no
GO:0045944 positive regulation of transcription by RNA polymerase II 25.0000 9 no
GO:0046928 regulation of neurotransmitter secretion 25.0000 5 no
GO:0048585 negative regulation of response to stimulus 25.0000 4 no
GO:0048638 regulation of developmental growth 25.0000 4 no
GO:0048639 positive regulation of developmental growth 25.0000 5 no
GO:0050890 cognition 25.0000 4 no
GO:0051046 regulation of secretion 25.0000 5 no
GO:0051093 negative regulation of developmental process 25.0000 4 no
GO:0051174 regulation of phosphorus metabolic process 25.0000 5 no
GO:0051246 regulation of protein metabolic process 25.0000 5 no
GO:0051247 positive regulation of protein metabolic process 25.0000 6 no
GO:0051254 positive regulation of RNA metabolic process 25.0000 6 no
GO:0051338 regulation of transferase activity 25.0000 4 no
GO:0051493 regulation of cytoskeleton organization 25.0000 6 no
GO:0051588 regulation of neurotransmitter transport 25.0000 5 no
GO:0060341 regulation of cellular localization 25.0000 4 no
GO:0062197 cellular response to chemical stress 25.0000 4 no
GO:0071241 cellular response to inorganic substance 25.0000 4 no
GO:0071248 cellular response to metal ion 25.0000 5 no
GO:0071407 cellular response to organic cyclic compound 25.0000 5 no
GO:0071417 cellular response to organonitrogen compound 25.0000 4 no
GO:0080134 regulation of response to stress 25.0000 4 no
GO:0080135 regulation of cellular response to stress 25.0000 4 no
GO:0098657 import into cell 25.0000 4 no
GO:0098916 anterograde trans-synaptic signaling 25.0000 6 no
GO:0099537 trans-synaptic signaling 25.0000 5 no
GO:1901699 cellular response to nitrogen compound 25.0000 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
LRRK2_HUMAN [view interactions] High throughput no yes
LRRK1_HUMAN [view interactions] High throughput no yes
APLP1_HUMAN [view interactions] High throughput no yes
MK03_HUMAN [view entry] [view interactions] High throughput yes yes
MYOME_HUMAN [view interactions] High throughput no no
RIMS1_HUMAN [view entry] [view interactions] High throughput yes yes
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
CHD8_HUMAN [view interactions] High throughput no no
DYR1A_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
STB5L_HUMAN [view interactions] High throughput no no
SUZ12_HUMAN [view interactions] High throughput no no
RING2_HUMAN [view interactions] High throughput no yes
PPT1_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
ALK_HUMAN [view entry] [view interactions] High throughput yes yes
IFNE_HUMAN [view interactions] High throughput no no
FKBP6_HUMAN [view interactions] High throughput no no
IFNA6_HUMAN [view interactions] High throughput no no
ANF_HUMAN [view interactions] High throughput no no
NOGG_HUMAN [view interactions] High throughput no yes
CGRE1_HUMAN [view interactions] High throughput no no
CRP_HUMAN [view interactions] High throughput no no
DKK3_HUMAN [view interactions] High throughput no yes
IL20_HUMAN [view interactions] High throughput no no
NXPH2_HUMAN [view interactions] High throughput no no
IL10_HUMAN [view interactions] High throughput no no
IFN10_HUMAN [view interactions] High throughput no no
EP3A_HUMAN [view interactions] High throughput no no
GLUC_HUMAN [view interactions] High throughput no no
MCH_HUMAN [view entry] [view interactions] High throughput yes no
VIP_HUMAN [view interactions] High throughput no no
PRG3_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no