Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CSMD2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

[View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CSMD2_HUMAN
GO:0019900 kinase binding 50.0000 4 no
GO:0019901 protein kinase binding 28.5714 5 no
GO:0016301 kinase activity 28.5714 4 no
GO:0001664 G protein-coupled receptor binding 28.5714 4 no
GO:0035254 glutamate receptor binding 28.5714 4 no
GO:0043169 cation binding 28.5714 4 no
GO:0046872 metal ion binding 28.5714 5 no
GO:0017124 SH3 domain binding 21.4286 4 no
GO:0030159 signaling receptor complex adaptor activity 21.4286 4 no
GO:0046875 ephrin receptor binding 21.4286 4 no
GO:0019902 phosphatase binding 21.4286 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in CSMD2_HUMAN
GO:0048522 positive regulation of cellular process 71.4286 4 no
GO:0010646 regulation of cell communication 64.2857 4 no
GO:0048523 negative regulation of cellular process 64.2857 4 no
GO:0051128 regulation of cellular component organization 64.2857 4 no
GO:0008104 protein localization 57.1429 4 no
GO:0009966 regulation of signal transduction 57.1429 4 no
GO:0060255 regulation of macromolecule metabolic process 57.1429 4 no
GO:0080090 regulation of primary metabolic process 57.1429 4 no
GO:0022603 regulation of anatomical structure morphogenesis 50.0000 4 no
GO:0022607 cellular component assembly 50.0000 4 no
GO:0031323 regulation of cellular metabolic process 50.0000 4 no
GO:0048584 positive regulation of response to stimulus 50.0000 4 no
GO:0051049 regulation of transport 50.0000 4 no
GO:0009967 positive regulation of signal transduction 42.8571 5 no
GO:0010647 positive regulation of cell communication 42.8571 5 no
GO:0023056 positive regulation of signaling 42.8571 4 no
GO:0030030 cell projection organization 42.8571 4 no
GO:0031344 regulation of cell projection organization 42.8571 5 no
GO:0048585 negative regulation of response to stimulus 42.8571 4 no
GO:0071363 cellular response to growth factor stimulus 42.8571 4 no
GO:0120036 plasma membrane bounded cell projection organization 42.8571 5 no
GO:0034762 regulation of transmembrane transport 42.8571 4 no
GO:0051130 positive regulation of cellular component organization 42.8571 5 no
GO:0050804 modulation of chemical synaptic transmission 42.8571 5 no
GO:0099177 regulation of trans-synaptic signaling 42.8571 4 no
GO:0009893 positive regulation of metabolic process 42.8571 4 no
GO:0010604 positive regulation of macromolecule metabolic process 42.8571 5 no
GO:0006996 organelle organization 35.7143 4 no
GO:0009889 regulation of biosynthetic process 35.7143 4 no
GO:0010468 regulation of gene expression 35.7143 6 no
GO:0010556 regulation of macromolecule biosynthetic process 35.7143 5 no
GO:0010975 regulation of neuron projection development 35.7143 7 no
GO:0030155 regulation of cell adhesion 35.7143 4 no
GO:0031326 regulation of cellular biosynthetic process 35.7143 5 no
GO:0033043 regulation of organelle organization 35.7143 5 no
GO:0051493 regulation of cytoskeleton organization 35.7143 6 no
GO:0072657 protein localization to membrane 35.7143 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 35.7143 6 no
GO:1902531 regulation of intracellular signal transduction 35.7143 5 no
GO:0042127 regulation of cell population proliferation 35.7143 4 no
GO:0043933 protein-containing complex organization 35.7143 4 no
GO:0141124 intracellular signaling cassette 35.7143 4 no
GO:0051094 positive regulation of developmental process 35.7143 4 no
GO:0031325 positive regulation of cellular metabolic process 35.7143 5 no
GO:0031346 positive regulation of cell projection organization 35.7143 6 no
GO:0051246 regulation of protein metabolic process 35.7143 5 no
GO:0051247 positive regulation of protein metabolic process 35.7143 6 no
GO:0002683 negative regulation of immune system process 28.5714 4 no
GO:0006355 regulation of DNA-templated transcription 28.5714 7 no
GO:0006357 regulation of transcription by RNA polymerase II 28.5714 8 no
GO:0007010 cytoskeleton organization 28.5714 5 no
GO:0007167 enzyme-linked receptor protein signaling pathway 28.5714 4 no
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway 28.5714 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 28.5714 5 no
GO:0022604 regulation of cell morphogenesis 28.5714 5 no
GO:0030334 regulation of cell migration 28.5714 5 no
GO:0031175 neuron projection development 28.5714 6 no
GO:0032956 regulation of actin cytoskeleton organization 28.5714 5 no
GO:0032970 regulation of actin filament-based process 28.5714 4 no
GO:0045785 positive regulation of cell adhesion 28.5714 5 no
GO:0050776 regulation of immune response 28.5714 4 no
GO:0051252 regulation of RNA metabolic process 28.5714 5 no
GO:0051336 regulation of hydrolase activity 28.5714 4 no
GO:0071310 cellular response to organic substance 28.5714 4 no
GO:0071559 response to transforming growth factor beta 28.5714 4 no
GO:0071560 cellular response to transforming growth factor beta stimulus 28.5714 5 no
GO:0080134 regulation of response to stress 28.5714 4 no
GO:1901701 cellular response to oxygen-containing compound 28.5714 4 no
GO:2000145 regulation of cell motility 28.5714 4 no
GO:2001141 regulation of RNA biosynthetic process 28.5714 6 no
GO:0006796 phosphate-containing compound metabolic process 28.5714 4 no
GO:0007268 chemical synaptic transmission 28.5714 7 no
GO:0008284 positive regulation of cell population proliferation 28.5714 5 no
GO:0009892 negative regulation of metabolic process 28.5714 4 no
GO:0009968 negative regulation of signal transduction 28.5714 5 no
GO:0010605 negative regulation of macromolecule metabolic process 28.5714 5 no
GO:0010648 negative regulation of cell communication 28.5714 5 no
GO:0010959 regulation of metal ion transport 28.5714 6 no
GO:0023057 negative regulation of signaling 28.5714 4 no
GO:0031324 negative regulation of cellular metabolic process 28.5714 5 no
GO:0033365 protein localization to organelle 28.5714 5 no
GO:0034765 regulation of monoatomic ion transmembrane transport 28.5714 5 no
GO:0035418 protein localization to synapse 28.5714 6 no
GO:0043113 receptor clustering 28.5714 5 no
GO:0043269 regulation of monoatomic ion transport 28.5714 5 no
GO:0044057 regulation of system process 28.5714 4 no
GO:0051050 positive regulation of transport 28.5714 4 no
GO:0065003 protein-containing complex assembly 28.5714 5 no
GO:0098916 anterograde trans-synaptic signaling 28.5714 6 no
GO:0099536 synaptic signaling 28.5714 4 no
GO:0099537 trans-synaptic signaling 28.5714 5 no
GO:1902414 protein localization to cell junction 28.5714 5 no
GO:1902532 negative regulation of intracellular signal transduction 28.5714 6 no
GO:1904062 regulation of monoatomic cation transmembrane transport 28.5714 6 no
GO:2000026 regulation of multicellular organismal development 28.5714 4 no
GO:0007612 learning 28.5714 4 no
GO:0050890 cognition 28.5714 4 no
GO:0010562 positive regulation of phosphorus metabolic process 28.5714 6 no
GO:0019220 regulation of phosphate metabolic process 28.5714 6 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0031401 positive regulation of protein modification process 28.5714 7 no
GO:0043085 positive regulation of catalytic activity 28.5714 4 no
GO:0045937 positive regulation of phosphate metabolic process 28.5714 7 no
GO:0051174 regulation of phosphorus metabolic process 28.5714 5 no
GO:0010976 positive regulation of neuron projection development 28.5714 7 no
GO:0042981 regulation of apoptotic process 28.5714 5 no
GO:0043067 regulation of programmed cell death 28.5714 4 no
GO:0051240 positive regulation of multicellular organismal process 28.5714 4 no
GO:0000302 response to reactive oxygen species 21.4286 4 no
GO:0001558 regulation of cell growth 21.4286 4 no
GO:0001764 neuron migration 21.4286 4 no
GO:0010243 response to organonitrogen compound 21.4286 4 no
GO:0010810 regulation of cell-substrate adhesion 21.4286 5 no
GO:0010811 positive regulation of cell-substrate adhesion 21.4286 6 no
GO:0030335 positive regulation of cell migration 21.4286 6 no
GO:0031347 regulation of defense response 21.4286 5 no
GO:0031348 negative regulation of defense response 21.4286 5 no
GO:0032101 regulation of response to external stimulus 21.4286 4 no
GO:0032102 negative regulation of response to external stimulus 21.4286 5 no
GO:0032880 regulation of protein localization 21.4286 5 no
GO:0040017 positive regulation of locomotion 21.4286 4 no
GO:0042542 response to hydrogen peroxide 21.4286 4 no
GO:0043393 regulation of protein binding 21.4286 4 no
GO:0043408 regulation of MAPK cascade 21.4286 6 no
GO:0050777 negative regulation of immune response 21.4286 5 no
GO:0060341 regulation of cellular localization 21.4286 4 no
GO:0071241 cellular response to inorganic substance 21.4286 4 no
GO:0071417 cellular response to organonitrogen compound 21.4286 4 no
GO:1901699 cellular response to nitrogen compound 21.4286 4 no
GO:1902533 positive regulation of intracellular signal transduction 21.4286 6 no
GO:1903829 positive regulation of protein localization 21.4286 5 no
GO:1905475 regulation of protein localization to membrane 21.4286 6 no
GO:1905477 positive regulation of protein localization to membrane 21.4286 6 no
GO:2000147 positive regulation of cell motility 21.4286 5 no
GO:0002694 regulation of leukocyte activation 21.4286 4 no
GO:0009890 negative regulation of biosynthetic process 21.4286 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 21.4286 6 no
GO:0022407 regulation of cell-cell adhesion 21.4286 5 no
GO:0022898 regulation of transmembrane transporter activity 21.4286 4 no
GO:0031327 negative regulation of cellular biosynthetic process 21.4286 6 no
GO:0032412 regulation of monoatomic ion transmembrane transporter activity 21.4286 5 no
GO:0032943 mononuclear cell proliferation 21.4286 4 no
GO:0034330 cell junction organization 21.4286 4 no
GO:0035088 establishment or maintenance of apical/basal cell polarity 21.4286 4 no
GO:0042098 T cell proliferation 21.4286 5 no
GO:0042110 T cell activation 21.4286 4 no
GO:0043270 positive regulation of monoatomic ion transport 21.4286 5 no
GO:0044087 regulation of cellular component biogenesis 21.4286 4 no
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 21.4286 5 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 21.4286 5 no
GO:0046651 lymphocyte proliferation 21.4286 4 no
GO:0050863 regulation of T cell activation 21.4286 6 no
GO:0050865 regulation of cell activation 21.4286 4 no
GO:0051249 regulation of lymphocyte activation 21.4286 5 no
GO:0110053 regulation of actin filament organization 21.4286 6 no
GO:1902903 regulation of supramolecular fiber organization 21.4286 5 no
GO:1903037 regulation of leukocyte cell-cell adhesion 21.4286 6 no
GO:0048812 neuron projection morphogenesis 21.4286 5 no
GO:0050885 neuromuscular process controlling balance 21.4286 5 no
GO:0050905 neuromuscular process 21.4286 4 no
GO:0051129 negative regulation of cellular component organization 21.4286 5 no
GO:0097061 dendritic spine organization 21.4286 5 no
GO:0099173 postsynapse organization 21.4286 4 no
GO:0106027 neuron projection organization 21.4286 6 no
GO:0120039 plasma membrane bounded cell projection morphogenesis 21.4286 4 no
GO:0001932 regulation of protein phosphorylation 21.4286 7 no
GO:0001934 positive regulation of protein phosphorylation 21.4286 8 no
GO:0030100 regulation of endocytosis 21.4286 5 no
GO:0042325 regulation of phosphorylation 21.4286 7 no
GO:0042327 positive regulation of phosphorylation 21.4286 8 no
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 21.4286 8 no
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 21.4286 9 no
GO:0060627 regulation of vesicle-mediated transport 21.4286 4 no
GO:0002429 immune response-activating cell surface receptor signaling pathway 21.4286 4 no
GO:0002684 positive regulation of immune system process 21.4286 4 no
GO:0002768 immune response-regulating cell surface receptor signaling pathway 21.4286 4 no
GO:0009894 regulation of catabolic process 21.4286 4 no
GO:0038093 Fc receptor signaling pathway 21.4286 5 no
GO:0043065 positive regulation of apoptotic process 21.4286 6 no
GO:0043068 positive regulation of programmed cell death 21.4286 5 no
GO:0050778 positive regulation of immune response 21.4286 5 no
GO:0050807 regulation of synapse organization 21.4286 5 no
GO:0050851 antigen receptor-mediated signaling pathway 21.4286 5 no
GO:0050852 T cell receptor signaling pathway 21.4286 6 no
GO:0051924 regulation of calcium ion transport 21.4286 7 no
GO:1903169 regulation of calcium ion transmembrane transport 21.4286 7 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG2_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG1_HUMAN [view entry] [view interactions] Low throughput yes yes
MAGI2_HUMAN [view entry] [view interactions] Low throughput yes yes
MPDZ_HUMAN [view entry] [view interactions] Low throughput yes yes
SHAN1_HUMAN [view entry] [view interactions] Low throughput yes yes
ABL1_HUMAN [view entry] [view interactions] High throughput yes yes
CRK_HUMAN [view entry] [view interactions] High throughput yes no
FYN_HUMAN [view entry] [view interactions] High throughput yes no
NCK1_HUMAN [view interactions] High throughput no yes
PLCG1_HUMAN [view entry] [view interactions] High throughput yes yes
MDHC_HUMAN [view entry] [view interactions] High throughput yes yes
MYC_HUMAN [view interactions] High throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
RN123_HUMAN [view interactions] High throughput no yes
RIGI_HUMAN [view interactions] High throughput no yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes