Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

GRASP_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in GRASP_HUMAN
GO:0017076 purine nucleotide binding 24.0000 4 no
GO:0032555 purine ribonucleotide binding 24.0000 4 no
GO:0035639 purine ribonucleoside triphosphate binding 24.0000 4 no
GO:0030165 PDZ domain binding 12.0000 4 yes
GO:0031267 small GTPase binding 8.0000 5 yes
GO:0051020 GTPase binding 8.0000 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in GRASP_HUMAN
GO:0010646 regulation of cell communication 72.0000 4 no
GO:0009966 regulation of signal transduction 60.0000 4 no
GO:0051049 regulation of transport 52.0000 4 yes
GO:0048522 positive regulation of cellular process 48.0000 4 no
GO:1902531 regulation of intracellular signal transduction 48.0000 5 no
GO:0050804 modulation of chemical synaptic transmission 48.0000 5 no
GO:0099177 regulation of trans-synaptic signaling 48.0000 4 no
GO:0048523 negative regulation of cellular process 48.0000 4 no
GO:0051171 regulation of nitrogen compound metabolic process 44.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 40.0000 4 no
GO:0080090 regulation of primary metabolic process 40.0000 4 no
GO:0031323 regulation of cellular metabolic process 40.0000 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 36.0000 5 no
GO:0051246 regulation of protein metabolic process 36.0000 5 no
GO:0009893 positive regulation of metabolic process 36.0000 4 no
GO:0010604 positive regulation of macromolecule metabolic process 36.0000 5 no
GO:0031325 positive regulation of cellular metabolic process 36.0000 5 no
GO:0045937 positive regulation of phosphate metabolic process 32.0000 7 no
GO:0051128 regulation of cellular component organization 32.0000 4 no
GO:0051174 regulation of phosphorus metabolic process 32.0000 5 no
GO:0051247 positive regulation of protein metabolic process 32.0000 6 no
GO:0043085 positive regulation of catalytic activity 32.0000 4 no
GO:0060627 regulation of vesicle-mediated transport 32.0000 4 yes
GO:0071310 cellular response to organic substance 32.0000 4 no
GO:0010562 positive regulation of phosphorus metabolic process 32.0000 6 no
GO:0019220 regulation of phosphate metabolic process 32.0000 6 no
GO:0031399 regulation of protein modification process 32.0000 6 no
GO:0031401 positive regulation of protein modification process 32.0000 7 no
GO:0042325 regulation of phosphorylation 28.0000 7 no
GO:0042327 positive regulation of phosphorylation 28.0000 8 no
GO:0048584 positive regulation of response to stimulus 28.0000 4 no
GO:0022603 regulation of anatomical structure morphogenesis 28.0000 4 no
GO:0032880 regulation of protein localization 28.0000 5 yes
GO:0060341 regulation of cellular localization 28.0000 4 yes
GO:0007268 chemical synaptic transmission 28.0000 6 no
GO:0098916 anterograde trans-synaptic signaling 28.0000 5 no
GO:0099537 trans-synaptic signaling 28.0000 4 no
GO:0001932 regulation of protein phosphorylation 28.0000 7 no
GO:0001934 positive regulation of protein phosphorylation 28.0000 8 no
GO:0009967 positive regulation of signal transduction 28.0000 5 no
GO:0010647 positive regulation of cell communication 28.0000 5 no
GO:0023056 positive regulation of signaling 28.0000 4 no
GO:0043412 macromolecule modification 24.0000 4 no
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 24.0000 8 no
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 24.0000 9 no
GO:0051050 positive regulation of transport 24.0000 4 no
GO:1902533 positive regulation of intracellular signal transduction 24.0000 6 no
GO:0030334 regulation of cell migration 24.0000 5 no
GO:0031344 regulation of cell projection organization 24.0000 5 no
GO:2000145 regulation of cell motility 24.0000 4 no
GO:0048585 negative regulation of response to stimulus 24.0000 4 no
GO:0008104 protein localization 24.0000 4 yes
GO:0051223 regulation of protein transport 24.0000 5 yes
GO:0070201 regulation of establishment of protein localization 24.0000 6 yes
GO:0044057 regulation of system process 24.0000 4 no
GO:0010468 regulation of gene expression 24.0000 5 no
GO:0030155 regulation of cell adhesion 24.0000 4 no
GO:0032101 regulation of response to external stimulus 24.0000 4 no
GO:0036211 protein modification process 24.0000 4 no
GO:0032386 regulation of intracellular transport 20.0000 5 yes
GO:0033157 regulation of intracellular protein transport 16.0000 6 yes
GO:1905475 regulation of protein localization to membrane 16.0000 6 yes
GO:1902473 regulation of protein localization to synapse 8.0000 6 yes
GO:1902683 regulation of receptor localization to synapse 8.0000 4 yes
GO:1903076 regulation of protein localization to plasma membrane 8.0000 7 yes
GO:1904375 regulation of protein localization to cell periphery 8.0000 6 yes
GO:1905749 regulation of endosome to plasma membrane protein transport 8.0000 6 yes
GO:2001135 regulation of endocytic recycling 8.0000 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CYH2_HUMAN [view entry] [view interactions] Low throughput yes yes
DLGP3_HUMAN [view entry] [view interactions] Low throughput yes yes
GRM5_HUMAN [view entry] [view interactions] Low throughput yes no
GRASP_HUMAN [view entry] [view interactions] Low throughput yes yes
MAGI2_HUMAN [view entry] [view interactions] Low throughput yes yes
APBA2_HUMAN [view interactions] Low throughput no yes
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
DLGP1_HUMAN [view entry] [view interactions] Low throughput yes no
CSKP_HUMAN [view entry] [view interactions] Low throughput yes yes
GRM1_HUMAN [view entry] [view interactions] Low throughput yes yes
GRM2_HUMAN [view entry] [view interactions] Low throughput yes yes
GRM3_HUMAN [view entry] [view interactions] Low throughput yes no
GBRB2_HUMAN [view entry] [view interactions] Low throughput yes no
CYH3_HUMAN [view entry] [view interactions] Low throughput yes yes
PSD1_HUMAN [view entry] [view interactions] Low throughput yes no
SRC_HUMAN [view entry] [view interactions] Low throughput yes no
PTN11_HUMAN [view entry] [view interactions] Low throughput yes yes
KSYK_HUMAN [view interactions] Low throughput no no
DOCK1_HUMAN [view entry] [view interactions] Low throughput yes yes
FYN_HUMAN [view entry] [view interactions] Low throughput yes no
GLU2B_HUMAN [view interactions] High throughput no yes
FCSD2_HUMAN [view interactions] High throughput no no
ZBTB5_HUMAN [view interactions] High throughput no yes
ZHX1_HUMAN [view interactions] High throughput no no
CEP83_HUMAN [view interactions] High throughput no yes
BCR_HUMAN [view entry] [view interactions] High throughput yes yes
AFF1_HUMAN [view interactions] High throughput no no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
ACE2_HUMAN [view interactions] High throughput no no
FRY_HUMAN [view interactions] High throughput no yes
CE170_HUMAN [view interactions] High throughput no yes
AFF2_HUMAN [view interactions] High throughput no yes
PSDE_HUMAN [view entry] [view interactions] High throughput yes yes
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
KS6A1_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] Computational no no
ARF1_HUMAN [view entry] [view interactions] Computational yes yes
NTRK3_HUMAN [view entry] [view interactions] Computational yes yes
MARH2_HUMAN [view interactions] Computational no yes