Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

MAGE1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in MAGE1_HUMAN
GO:0003779 actin binding 33.3333 4 no
GO:0046872 metal ion binding 33.3333 4 no
GO:0005524 ATP binding 33.3333 5 no
GO:0017076 purine nucleotide binding 33.3333 4 no
GO:0030554 adenyl nucleotide binding 33.3333 5 no
GO:0032555 purine ribonucleotide binding 33.3333 4 no
GO:0032559 adenyl ribonucleotide binding 33.3333 5 no
GO:0035639 purine ribonucleoside triphosphate binding 33.3333 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in MAGE1_HUMAN
GO:0048523 negative regulation of cellular process 83.3333 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 83.3333 4 yes
GO:0060255 regulation of macromolecule metabolic process 83.3333 4 yes
GO:0080090 regulation of primary metabolic process 83.3333 4 yes
GO:0009892 negative regulation of metabolic process 66.6667 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 66.6667 5 yes
GO:0031323 regulation of cellular metabolic process 66.6667 4 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 66.6667 5 yes
GO:0009889 regulation of biosynthetic process 50.0000 4 yes
GO:0009890 negative regulation of biosynthetic process 50.0000 5 yes
GO:0010468 regulation of gene expression 50.0000 5 yes
GO:0031324 negative regulation of cellular metabolic process 50.0000 5 yes
GO:0031326 regulation of cellular biosynthetic process 50.0000 5 yes
GO:0031327 negative regulation of cellular biosynthetic process 50.0000 6 yes
GO:0031399 regulation of protein modification process 50.0000 6 no
GO:0051246 regulation of protein metabolic process 50.0000 5 no
GO:0031400 negative regulation of protein modification process 33.3333 7 no
GO:0034762 regulation of transmembrane transport 33.3333 4 no
GO:0034765 regulation of ion transmembrane transport 33.3333 5 no
GO:0043269 regulation of ion transport 33.3333 5 no
GO:0051049 regulation of transport 33.3333 4 no
GO:0051248 negative regulation of protein metabolic process 33.3333 6 no
GO:1904062 regulation of cation transmembrane transport 33.3333 6 no
GO:0009966 regulation of signal transduction 33.3333 4 no
GO:0010646 regulation of cell communication 33.3333 4 no
GO:0048585 negative regulation of response to stimulus 33.3333 4 no
GO:1902531 regulation of intracellular signal transduction 33.3333 5 no
GO:0000122 negative regulation of transcription by RNA polymerase II 33.3333 8 yes
GO:0006355 regulation of DNA-templated transcription 33.3333 6 yes
GO:0006357 regulation of transcription by RNA polymerase II 33.3333 7 yes
GO:0010556 regulation of macromolecule biosynthetic process 33.3333 5 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 33.3333 6 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 33.3333 5 yes
GO:0045892 negative regulation of DNA-templated transcription 33.3333 7 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 33.3333 6 yes
GO:0051252 regulation of RNA metabolic process 33.3333 5 yes
GO:0051253 negative regulation of RNA metabolic process 33.3333 6 yes
GO:1902679 negative regulation of RNA biosynthetic process 33.3333 7 yes
GO:1903506 regulation of nucleic acid-templated transcription 33.3333 7 yes
GO:1903507 negative regulation of nucleic acid-templated transcription 33.3333 8 yes
GO:2001141 regulation of RNA biosynthetic process 33.3333 6 yes
GO:0001932 regulation of protein phosphorylation 33.3333 7 no
GO:0001934 positive regulation of protein phosphorylation 33.3333 8 no
GO:0009893 positive regulation of metabolic process 33.3333 4 no
GO:0010562 positive regulation of phosphorus metabolic process 33.3333 6 no
GO:0010604 positive regulation of macromolecule metabolic process 33.3333 5 no
GO:0019220 regulation of phosphate metabolic process 33.3333 6 no
GO:0030155 regulation of cell adhesion 33.3333 4 no
GO:0031325 positive regulation of cellular metabolic process 33.3333 5 no
GO:0031401 positive regulation of protein modification process 33.3333 7 no
GO:0042325 regulation of phosphorylation 33.3333 7 no
GO:0042327 positive regulation of phosphorylation 33.3333 8 no
GO:0045937 positive regulation of phosphate metabolic process 33.3333 7 no
GO:0048522 positive regulation of cellular process 33.3333 4 no
GO:0051128 regulation of cellular component organization 33.3333 4 no
GO:0051130 positive regulation of cellular component organization 33.3333 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 33.3333 5 no
GO:0051174 regulation of phosphorus metabolic process 33.3333 5 no
GO:0051247 positive regulation of protein metabolic process 33.3333 6 no
GO:0010959 regulation of metal ion transport 33.3333 6 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TIF1B_HUMAN [view interactions] Low throughput no yes
MAGE1_HUMAN [view entry] [view interactions] Low throughput yes yes
SNTA1_HUMAN [view entry] [view interactions] Low throughput yes no
UBP7_HUMAN [view interactions] High throughput no yes
IQCB1_HUMAN [view interactions] High throughput no no
CRML_HUMAN [view interactions] High throughput no yes
P66B_HUMAN [view interactions] High throughput no yes
EID2_HUMAN [view interactions] High throughput no yes
C19L2_HUMAN [view interactions] High throughput no yes
EID2B_HUMAN [view interactions] High throughput no no
RASA1_HUMAN [view interactions] High throughput no yes
PEBP1_HUMAN [view entry] [view interactions] High throughput yes yes
CRCM_HUMAN [view interactions] High throughput no no
YLPM1_HUMAN [view interactions] High throughput no yes
BCAS3_HUMAN [view interactions] High throughput no yes
PHAF1_HUMAN [view interactions] High throughput no yes
KDIS_HUMAN [view interactions] High throughput no yes
PINK1_HUMAN [view interactions] High throughput no yes
SYNCI_HUMAN [view interactions] High throughput no no
GCP5_HUMAN [view interactions] High throughput no yes
YJEN3_HUMAN [view interactions] High throughput no yes
KBTB6_HUMAN [view interactions] High throughput no yes
NSE4A_HUMAN [view interactions] High throughput no yes
DCA11_HUMAN [view interactions] High throughput no yes
SIN3A_HUMAN [view interactions] High throughput no yes
LIMC1_HUMAN [view entry] [view interactions] High throughput yes no
CORO6_HUMAN [view interactions] High throughput no no
NSE1_HUMAN [view interactions] High throughput no yes
PCYOX_HUMAN [view interactions] High throughput no yes
FYN_HUMAN [view entry] [view interactions] High throughput yes no
NSE3_HUMAN [view interactions] High throughput no no