Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

MAGE1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in MAGE1_HUMAN
GO:0003779 actin binding 37.5000 4 no
GO:0030165 PDZ domain binding 37.5000 4 no
GO:0043169 cation binding 37.5000 4 no
GO:0046872 metal ion binding 37.5000 5 no
GO:0001664 G protein-coupled receptor binding 25.0000 4 no
GO:0015631 tubulin binding 25.0000 4 no
GO:0019900 kinase binding 25.0000 4 no
GO:0019901 protein kinase binding 25.0000 5 no
GO:0043274 phospholipase binding 25.0000 4 no
GO:0000166 nucleotide binding 25.0000 4 no
GO:0005524 ATP binding 25.0000 5 no
GO:0017076 purine nucleotide binding 25.0000 5 no
GO:0030554 adenyl nucleotide binding 25.0000 6 no
GO:0032555 purine ribonucleotide binding 25.0000 4 no
GO:0032559 adenyl ribonucleotide binding 25.0000 5 no
GO:0035639 purine ribonucleoside triphosphate binding 25.0000 4 no
GO:0043168 anion binding 25.0000 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in MAGE1_HUMAN
GO:0048523 negative regulation of cellular process 75.0000 4 yes
GO:0060255 regulation of macromolecule metabolic process 75.0000 4 yes
GO:0080090 regulation of primary metabolic process 75.0000 4 yes
GO:0009892 negative regulation of metabolic process 62.5000 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 62.5000 5 yes
GO:0031323 regulation of cellular metabolic process 62.5000 4 yes
GO:0009889 regulation of biosynthetic process 50.0000 4 yes
GO:0009890 negative regulation of biosynthetic process 50.0000 5 yes
GO:0010468 regulation of gene expression 50.0000 6 yes
GO:0010556 regulation of macromolecule biosynthetic process 50.0000 5 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 50.0000 6 yes
GO:0031324 negative regulation of cellular metabolic process 50.0000 5 yes
GO:0031326 regulation of cellular biosynthetic process 50.0000 5 yes
GO:0031327 negative regulation of cellular biosynthetic process 50.0000 6 yes
GO:0031399 regulation of protein modification process 50.0000 6 no
GO:0048522 positive regulation of cellular process 50.0000 4 no
GO:0051128 regulation of cellular component organization 50.0000 4 no
GO:0051130 positive regulation of cellular component organization 50.0000 5 no
GO:0051246 regulation of protein metabolic process 50.0000 5 no
GO:0000122 negative regulation of transcription by RNA polymerase II 37.5000 9 yes
GO:0006355 regulation of DNA-templated transcription 37.5000 7 yes
GO:0006357 regulation of transcription by RNA polymerase II 37.5000 8 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 37.5000 5 yes
GO:0045892 negative regulation of DNA-templated transcription 37.5000 8 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 37.5000 5 yes
GO:0051252 regulation of RNA metabolic process 37.5000 5 yes
GO:0051253 negative regulation of RNA metabolic process 37.5000 6 yes
GO:1902679 negative regulation of RNA biosynthetic process 37.5000 7 yes
GO:2001141 regulation of RNA biosynthetic process 37.5000 6 yes
GO:0001932 regulation of protein phosphorylation 37.5000 7 no
GO:0009893 positive regulation of metabolic process 37.5000 4 no
GO:0009966 regulation of signal transduction 37.5000 4 no
GO:0009968 negative regulation of signal transduction 37.5000 5 no
GO:0010604 positive regulation of macromolecule metabolic process 37.5000 5 no
GO:0010646 regulation of cell communication 37.5000 4 no
GO:0010648 negative regulation of cell communication 37.5000 5 no
GO:0019220 regulation of phosphate metabolic process 37.5000 6 no
GO:0023057 negative regulation of signaling 37.5000 4 no
GO:0031325 positive regulation of cellular metabolic process 37.5000 5 no
GO:0031400 negative regulation of protein modification process 37.5000 7 no
GO:0031401 positive regulation of protein modification process 37.5000 7 no
GO:0042325 regulation of phosphorylation 37.5000 7 no
GO:0048585 negative regulation of response to stimulus 37.5000 4 no
GO:0051049 regulation of transport 37.5000 4 no
GO:0051174 regulation of phosphorus metabolic process 37.5000 5 no
GO:0051247 positive regulation of protein metabolic process 37.5000 6 no
GO:0051248 negative regulation of protein metabolic process 37.5000 6 no
GO:1902531 regulation of intracellular signal transduction 37.5000 5 no
GO:1902532 negative regulation of intracellular signal transduction 37.5000 6 no
GO:0006996 organelle organization 25.0000 4 no
GO:0007612 learning 25.0000 4 no
GO:0009057 macromolecule catabolic process 25.0000 4 no
GO:0009894 regulation of catabolic process 25.0000 4 no
GO:0009967 positive regulation of signal transduction 25.0000 5 no
GO:0010243 response to organonitrogen compound 25.0000 4 no
GO:0010629 negative regulation of gene expression 25.0000 7 no
GO:0010638 positive regulation of organelle organization 25.0000 6 no
GO:0010647 positive regulation of cell communication 25.0000 5 no
GO:0016567 protein ubiquitination 25.0000 8 no
GO:0022603 regulation of anatomical structure morphogenesis 25.0000 4 no
GO:0022604 regulation of cell morphogenesis 25.0000 5 no
GO:0023056 positive regulation of signaling 25.0000 4 no
GO:0030162 regulation of proteolysis 25.0000 6 no
GO:0030163 protein catabolic process 25.0000 4 no
GO:0031396 regulation of protein ubiquitination 25.0000 9 no
GO:0032231 regulation of actin filament bundle assembly 25.0000 5 no
GO:0032446 protein modification by small protein conjugation 25.0000 7 no
GO:0032880 regulation of protein localization 25.0000 5 no
GO:0032956 regulation of actin cytoskeleton organization 25.0000 5 no
GO:0032970 regulation of actin filament-based process 25.0000 4 no
GO:0033043 regulation of organelle organization 25.0000 5 no
GO:0034599 cellular response to oxidative stress 25.0000 4 no
GO:0036211 protein modification process 25.0000 4 no
GO:0042176 regulation of protein catabolic process 25.0000 5 no
GO:0042981 regulation of apoptotic process 25.0000 5 no
GO:0043066 negative regulation of apoptotic process 25.0000 6 no
GO:0043067 regulation of programmed cell death 25.0000 4 no
GO:0043069 negative regulation of programmed cell death 25.0000 5 no
GO:0043122 regulation of canonical NF-kappaB signal transduction 25.0000 6 no
GO:0043123 positive regulation of canonical NF-kappaB signal transduction 25.0000 7 no
GO:0043408 regulation of MAPK cascade 25.0000 6 no
GO:0043409 negative regulation of MAPK cascade 25.0000 7 no
GO:0043412 macromolecule modification 25.0000 4 no
GO:0043687 post-translational protein modification 25.0000 5 no
GO:0044087 regulation of cellular component biogenesis 25.0000 4 no
GO:0045862 positive regulation of proteolysis 25.0000 7 no
GO:0048584 positive regulation of response to stimulus 25.0000 4 no
GO:0050804 modulation of chemical synaptic transmission 25.0000 5 no
GO:0050890 cognition 25.0000 4 no
GO:0051129 negative regulation of cellular component organization 25.0000 5 no
GO:0051493 regulation of cytoskeleton organization 25.0000 6 no
GO:0060341 regulation of cellular localization 25.0000 4 no
GO:0062197 cellular response to chemical stress 25.0000 4 no
GO:0070201 regulation of establishment of protein localization 25.0000 6 no
GO:0070647 protein modification by small protein conjugation or removal 25.0000 6 no
GO:0071310 cellular response to organic substance 25.0000 4 no
GO:0071417 cellular response to organonitrogen compound 25.0000 4 no
GO:0080134 regulation of response to stress 25.0000 4 no
GO:0099177 regulation of trans-synaptic signaling 25.0000 4 no
GO:0110053 regulation of actin filament organization 25.0000 6 no
GO:1901565 organonitrogen compound catabolic process 25.0000 4 no
GO:1901699 cellular response to nitrogen compound 25.0000 4 no
GO:1901701 cellular response to oxygen-containing compound 25.0000 4 no
GO:1901873 regulation of post-translational protein modification 25.0000 7 no
GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 25.0000 7 no
GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 25.0000 8 no
GO:1902533 positive regulation of intracellular signal transduction 25.0000 6 no
GO:1902903 regulation of supramolecular fiber organization 25.0000 5 no
GO:1903320 regulation of protein modification by small protein conjugation or removal 25.0000 8 no
GO:1903533 regulation of protein targeting 25.0000 7 no
GO:1903829 positive regulation of protein localization 25.0000 5 no
GO:1905475 regulation of protein localization to membrane 25.0000 6 no
GO:1905477 positive regulation of protein localization to membrane 25.0000 6 no
GO:2000377 regulation of reactive oxygen species metabolic process 25.0000 5 no
GO:2000378 negative regulation of reactive oxygen species metabolic process 25.0000 6 no
GO:2001233 regulation of apoptotic signaling pathway 25.0000 5 no
GO:2001234 negative regulation of apoptotic signaling pathway 25.0000 6 no
GO:2001242 regulation of intrinsic apoptotic signaling pathway 25.0000 6 no
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 25.0000 7 no
GO:0010959 regulation of metal ion transport 25.0000 6 no
GO:0034762 regulation of transmembrane transport 25.0000 4 no
GO:0034765 regulation of monoatomic ion transmembrane transport 25.0000 5 no
GO:0043269 regulation of monoatomic ion transport 25.0000 5 no
GO:1904062 regulation of monoatomic cation transmembrane transport 25.0000 6 no
GO:0001934 positive regulation of protein phosphorylation 25.0000 8 no
GO:0010562 positive regulation of phosphorus metabolic process 25.0000 6 no
GO:0010975 regulation of neuron projection development 25.0000 7 no
GO:0010976 positive regulation of neuron projection development 25.0000 7 no
GO:0030030 cell projection organization 25.0000 4 no
GO:0030155 regulation of cell adhesion 25.0000 4 no
GO:0031344 regulation of cell projection organization 25.0000 5 no
GO:0031346 positive regulation of cell projection organization 25.0000 6 no
GO:0042327 positive regulation of phosphorylation 25.0000 8 no
GO:0045937 positive regulation of phosphate metabolic process 25.0000 7 no
GO:0048812 neuron projection morphogenesis 25.0000 5 no
GO:0048813 dendrite morphogenesis 25.0000 6 no
GO:0071363 cellular response to growth factor stimulus 25.0000 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 25.0000 6 no
GO:0120039 plasma membrane bounded cell projection morphogenesis 25.0000 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TIF1B_HUMAN [view interactions] Low throughput no yes
MAGE1_HUMAN [view entry] [view interactions] Low throughput yes yes
SNTA1_HUMAN [view entry] [view interactions] Low throughput yes no
UBP7_HUMAN [view interactions] High throughput no yes
IQCB1_HUMAN [view interactions] High throughput no no
C19L2_HUMAN [view interactions] High throughput no yes
EID2_HUMAN [view interactions] High throughput no yes
P66B_HUMAN [view interactions] High throughput no yes
CRML_HUMAN [view interactions] High throughput no yes
EID2B_HUMAN [view interactions] High throughput no no
RASA1_HUMAN [view interactions] High throughput no yes
PEBP1_HUMAN [view entry] [view interactions] High throughput yes yes
CRCM_HUMAN [view interactions] High throughput no no
YLPM1_HUMAN [view interactions] High throughput no yes
BCAS3_HUMAN [view interactions] High throughput no yes
PHAF1_HUMAN [view interactions] High throughput no yes
KDIS_HUMAN [view entry] [view interactions] High throughput yes yes
PINK1_HUMAN [view interactions] High throughput no yes
SYNCI_HUMAN [view interactions] High throughput no no
GCP5_HUMAN [view interactions] High throughput no yes
YJEN3_HUMAN [view interactions] High throughput no yes
KBTB6_HUMAN [view interactions] High throughput no yes
NSE4A_HUMAN [view interactions] High throughput no yes
DCA11_HUMAN [view interactions] High throughput no yes
SIN3A_HUMAN [view interactions] High throughput no yes
LIMC1_HUMAN [view entry] [view interactions] High throughput yes no
CORO6_HUMAN [view interactions] High throughput no no
NSE1_HUMAN [view interactions] High throughput no yes
PCYOX_HUMAN [view interactions] High throughput no yes
FYN_HUMAN [view entry] [view interactions] High throughput yes no
NSE3_HUMAN [view interactions] High throughput no no
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes