Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RHG33_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May be involved in several stages of intracellular trafficking. Could play an important role in the regulation of glucose transport by insulin. May act as a downstream effector of RHOQ/TC10 in the regulation of insulin-stimulated glucose transport . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in RHG33_HUMAN
GO:0019900 kinase binding 46.1538 4 yes
GO:0019901 protein kinase binding 38.4615 5 yes
GO:0043169 cation binding 30.7692 4 no
GO:0046872 metal ion binding 30.7692 5 no
GO:0000166 nucleotide binding 30.7692 4 no
GO:0017076 purine nucleotide binding 30.7692 5 no
GO:0032555 purine ribonucleotide binding 30.7692 4 no
GO:0035639 purine ribonucleoside triphosphate binding 30.7692 4 no
GO:0043168 anion binding 30.7692 4 no
GO:0031625 ubiquitin protein ligase binding 23.0769 5 no
GO:0044389 ubiquitin-like protein ligase binding 23.0769 4 no
GO:0003723 RNA binding 23.0769 4 no
GO:0004842 ubiquitin-protein transferase activity 23.0769 4 no
GO:0016755 aminoacyltransferase activity 23.0769 4 no
GO:0061630 ubiquitin protein ligase activity 23.0769 5 no
GO:0061659 ubiquitin-like protein ligase activity 23.0769 4 no
GO:0035091 phosphatidylinositol binding 15.3846 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RHG33_HUMAN
GO:0051128 regulation of cellular component organization 76.9231 4 yes
GO:0048522 positive regulation of cellular process 76.9231 4 no
GO:0048584 positive regulation of response to stimulus 69.2308 4 no
GO:0060255 regulation of macromolecule metabolic process 69.2308 4 no
GO:0009966 regulation of signal transduction 61.5385 4 no
GO:0010646 regulation of cell communication 61.5385 4 no
GO:0048523 negative regulation of cellular process 61.5385 4 no
GO:0080090 regulation of primary metabolic process 61.5385 4 no
GO:0022607 cellular component assembly 53.8462 4 no
GO:0030030 cell projection organization 53.8462 4 no
GO:0031323 regulation of cellular metabolic process 53.8462 4 no
GO:0006996 organelle organization 46.1538 4 no
GO:0009967 positive regulation of signal transduction 46.1538 5 no
GO:0010647 positive regulation of cell communication 46.1538 5 no
GO:0023056 positive regulation of signaling 46.1538 4 no
GO:0031175 neuron projection development 46.1538 6 no
GO:0120036 plasma membrane bounded cell projection organization 46.1538 5 no
GO:0009893 positive regulation of metabolic process 46.1538 4 no
GO:0010604 positive regulation of macromolecule metabolic process 46.1538 5 no
GO:0051246 regulation of protein metabolic process 46.1538 5 no
GO:0008104 protein localization 38.4615 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 38.4615 4 yes
GO:0031344 regulation of cell projection organization 38.4615 5 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 38.4615 6 yes
GO:0141124 intracellular signaling cassette 38.4615 4 yes
GO:0051049 regulation of transport 38.4615 4 no
GO:0051130 positive regulation of cellular component organization 38.4615 5 no
GO:0007010 cytoskeleton organization 38.4615 5 no
GO:0009889 regulation of biosynthetic process 38.4615 4 no
GO:0010468 regulation of gene expression 38.4615 6 no
GO:0010556 regulation of macromolecule biosynthetic process 38.4615 5 no
GO:0030155 regulation of cell adhesion 38.4615 4 no
GO:0030334 regulation of cell migration 38.4615 5 no
GO:0030335 positive regulation of cell migration 38.4615 6 no
GO:0031326 regulation of cellular biosynthetic process 38.4615 5 no
GO:0032101 regulation of response to external stimulus 38.4615 4 no
GO:0032880 regulation of protein localization 38.4615 5 no
GO:0040017 positive regulation of locomotion 38.4615 4 no
GO:0060341 regulation of cellular localization 38.4615 4 no
GO:0080134 regulation of response to stress 38.4615 4 no
GO:1902531 regulation of intracellular signal transduction 38.4615 5 no
GO:1902533 positive regulation of intracellular signal transduction 38.4615 6 no
GO:2000145 regulation of cell motility 38.4615 4 no
GO:2000147 positive regulation of cell motility 38.4615 5 no
GO:0006508 proteolysis 38.4615 4 no
GO:0051247 positive regulation of protein metabolic process 38.4615 6 no
GO:0009057 macromolecule catabolic process 38.4615 4 no
GO:0036211 protein modification process 38.4615 4 no
GO:0043412 macromolecule modification 38.4615 4 no
GO:0050807 regulation of synapse organization 30.7692 5 yes
GO:0099175 regulation of postsynapse organization 30.7692 6 yes
GO:0061024 membrane organization 30.7692 4 no
GO:0001558 regulation of cell growth 30.7692 4 no
GO:0001764 neuron migration 30.7692 4 no
GO:0007167 enzyme-linked receptor protein signaling pathway 30.7692 4 no
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway 30.7692 5 no
GO:0022604 regulation of cell morphogenesis 30.7692 5 no
GO:0030307 positive regulation of cell growth 30.7692 5 no
GO:0032956 regulation of actin cytoskeleton organization 30.7692 5 no
GO:0032970 regulation of actin filament-based process 30.7692 4 no
GO:0033043 regulation of organelle organization 30.7692 5 no
GO:0045785 positive regulation of cell adhesion 30.7692 5 no
GO:0045927 positive regulation of growth 30.7692 4 no
GO:0048585 negative regulation of response to stimulus 30.7692 4 no
GO:0051493 regulation of cytoskeleton organization 30.7692 6 no
GO:0071310 cellular response to organic substance 30.7692 4 no
GO:1903829 positive regulation of protein localization 30.7692 5 no
GO:0030162 regulation of proteolysis 30.7692 6 no
GO:0043254 regulation of protein-containing complex assembly 30.7692 5 no
GO:0044087 regulation of cellular component biogenesis 30.7692 4 no
GO:0045862 positive regulation of proteolysis 30.7692 7 no
GO:0002684 positive regulation of immune system process 30.7692 4 no
GO:0009892 negative regulation of metabolic process 30.7692 4 no
GO:0010605 negative regulation of macromolecule metabolic process 30.7692 5 no
GO:0031324 negative regulation of cellular metabolic process 30.7692 5 no
GO:0031399 regulation of protein modification process 30.7692 6 no
GO:0032103 positive regulation of response to external stimulus 30.7692 5 no
GO:0016567 protein ubiquitination 30.7692 8 no
GO:0032446 protein modification by small protein conjugation 30.7692 7 no
GO:0043687 post-translational protein modification 30.7692 5 no
GO:0070647 protein modification by small protein conjugation or removal 30.7692 6 no
GO:0007264 small GTPase-mediated signal transduction 23.0769 5 yes
GO:0010975 regulation of neuron projection development 23.0769 7 yes
GO:0030100 regulation of endocytosis 23.0769 5 no
GO:0051050 positive regulation of transport 23.0769 4 no
GO:0060627 regulation of vesicle-mediated transport 23.0769 4 no
GO:0002685 regulation of leukocyte migration 23.0769 4 no
GO:0002831 regulation of response to biotic stimulus 23.0769 4 no
GO:0010810 regulation of cell-substrate adhesion 23.0769 5 no
GO:0010811 positive regulation of cell-substrate adhesion 23.0769 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 23.0769 5 no
GO:0031347 regulation of defense response 23.0769 5 no
GO:0045088 regulation of innate immune response 23.0769 5 no
GO:0050776 regulation of immune response 23.0769 4 no
GO:0051336 regulation of hydrolase activity 23.0769 4 no
GO:1900024 regulation of substrate adhesion-dependent cell spreading 23.0769 6 no
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 23.0769 7 no
GO:1905475 regulation of protein localization to membrane 23.0769 6 no
GO:0007411 axon guidance 23.0769 8 no
GO:0030031 cell projection assembly 23.0769 5 no
GO:0051604 protein maturation 23.0769 4 no
GO:0097485 neuron projection guidance 23.0769 7 no
GO:0110053 regulation of actin filament organization 23.0769 6 no
GO:1902903 regulation of supramolecular fiber organization 23.0769 5 no
GO:0019220 regulation of phosphate metabolic process 23.0769 6 no
GO:0051174 regulation of phosphorus metabolic process 23.0769 5 no
GO:0051726 regulation of cell cycle 23.0769 4 no
GO:0070201 regulation of establishment of protein localization 23.0769 6 no
GO:1904951 positive regulation of establishment of protein localization 23.0769 6 no
GO:0009890 negative regulation of biosynthetic process 23.0769 5 no
GO:0009894 regulation of catabolic process 23.0769 4 no
GO:0009968 negative regulation of signal transduction 23.0769 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 23.0769 6 no
GO:0010629 negative regulation of gene expression 23.0769 7 no
GO:0010648 negative regulation of cell communication 23.0769 5 no
GO:0023057 negative regulation of signaling 23.0769 4 no
GO:0030163 protein catabolic process 23.0769 4 no
GO:0031325 positive regulation of cellular metabolic process 23.0769 5 no
GO:0031327 negative regulation of cellular biosynthetic process 23.0769 6 no
GO:0031346 positive regulation of cell projection organization 23.0769 6 no
GO:0031401 positive regulation of protein modification process 23.0769 7 no
GO:0042176 regulation of protein catabolic process 23.0769 5 no
GO:0042981 regulation of apoptotic process 23.0769 5 no
GO:0043067 regulation of programmed cell death 23.0769 4 no
GO:0048812 neuron projection morphogenesis 23.0769 5 no
GO:0051129 negative regulation of cellular component organization 23.0769 5 no
GO:0099173 postsynapse organization 23.0769 4 no
GO:0120039 plasma membrane bounded cell projection morphogenesis 23.0769 4 no
GO:1901565 organonitrogen compound catabolic process 23.0769 4 no
GO:0006511 ubiquitin-dependent protein catabolic process 23.0769 7 no
GO:0019941 modification-dependent protein catabolic process 23.0769 6 no
GO:0043632 modification-dependent macromolecule catabolic process 23.0769 5 no
GO:0044089 positive regulation of cellular component biogenesis 23.0769 5 no
GO:0051603 proteolysis involved in protein catabolic process 23.0769 5 no
GO:0034097 response to cytokine 23.0769 4 no
GO:0042127 regulation of cell population proliferation 23.0769 4 no
GO:0043933 protein-containing complex organization 23.0769 4 no
GO:0065003 protein-containing complex assembly 23.0769 5 no
GO:0034330 cell junction organization 23.0769 4 no
GO:0045216 cell-cell junction organization 23.0769 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
FYN_HUMAN [view entry] [view interactions] Low throughput yes no
CDC42_HUMAN [view entry] [view interactions] Low throughput yes yes
CRK_HUMAN [view entry] [view interactions] Low throughput yes no
RHOJ_HUMAN [view interactions] Low throughput no yes
ADA10_HUMAN [view entry] [view interactions] High throughput yes yes
E41L3_HUMAN [view entry] [view interactions] High throughput yes yes
FGD6_HUMAN [view interactions] High throughput no yes
HDX_HUMAN [view interactions] High throughput no yes
MGAP_HUMAN [view interactions] High throughput no yes
PSME3_HUMAN [view interactions] High throughput no yes
RBL1_HUMAN [view interactions] High throughput no yes
RBM5_HUMAN [view interactions] High throughput no yes
LRIF1_HUMAN [view interactions] High throughput no yes
TAB1_HUMAN [view interactions] High throughput no yes
TRI32_HUMAN [view entry] [view interactions] High throughput yes yes
M3K7_HUMAN [view interactions] High throughput no yes
INSR_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
NEK6_HUMAN [view interactions] High throughput no yes
CRTP1_HUMAN [view interactions] High throughput no yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
CHIP_HUMAN [view entry] [view interactions] High throughput yes yes
RIF1_HUMAN [view interactions] High throughput no yes
ANFY1_HUMAN [view entry] [view interactions] High throughput yes yes
GID8_HUMAN [view interactions] High throughput no yes
CAMP3_HUMAN [view interactions] High throughput no no
DYR1B_HUMAN [view interactions] High throughput no no
GAR1_HUMAN [view interactions] High throughput no yes
HDAC2_HUMAN [view interactions] High throughput no yes
RT07_HUMAN [view interactions] High throughput no yes
MYCBP_HUMAN [view interactions] High throughput no yes
UBA1_HUMAN [view entry] [view interactions] High throughput yes yes
PRC1_HUMAN [view interactions] High throughput no yes
SMCA2_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
CYFP2_HUMAN [view entry] [view interactions] High throughput yes yes
TOP3B_HUMAN [view interactions] High throughput no no
P53_HUMAN [view interactions] High throughput no no