THY1_HUMAN
Evidence for PS localization
Functions
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. [View more on UniProt]
Protein features
Phase separation
ELM
Phosphorylation
PFAM
Coiled coil
Anchor
Disordered
Interacting regions
Sequence
LOADING 91%
![](/static/images/legend1.gif)
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
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THY1_HUMAN has binary interactions with 25 proteins
Isoforms
Interacting regions
Canonical [THY1_HUMAN]
Isoform [E9PNQ8] alignment
Isoform [E9PIM6] alignment
Isoform [E9PIE1] alignment
Isoform [J3QRJ3] alignment
LOADING 91%
![](/static/images/legend3.gif)
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in THY1_HUMAN |
---|---|---|---|---|
GO:0000166 | nucleotide binding | 30.7692 | 4 | no |
GO:0017076 | purine nucleotide binding | 26.9231 | 5 | no |
GO:0043169 | cation binding | 26.9231 | 4 | no |
GO:0046872 | metal ion binding | 26.9231 | 5 | no |
GO:0019900 | kinase binding | 26.9231 | 4 | yes |
GO:0030554 | adenyl nucleotide binding | 23.0769 | 6 | no |
GO:0032555 | purine ribonucleotide binding | 23.0769 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 23.0769 | 4 | no |
GO:0043168 | anion binding | 23.0769 | 4 | no |
GO:0019901 | protein kinase binding | 15.3846 | 5 | yes |
GO:0030695 | GTPase regulator activity | 11.5385 | 4 | yes |
GO:0035091 | phosphatidylinositol binding | 11.5385 | 4 | yes |
GO:0005096 | GTPase activator activity | 11.5385 | 4 | yes |
GO:0034235 | GPI anchor binding | 7.6923 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in THY1_HUMAN |
---|---|---|---|---|
GO:0048523 | negative regulation of cellular process | 65.3846 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 61.5385 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 57.6923 | 4 | yes |
GO:0009966 | regulation of signal transduction | 53.8462 | 4 | yes |
GO:0010646 | regulation of cell communication | 53.8462 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 50.0000 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 46.1538 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 46.1538 | 5 | yes |
GO:0006996 | organelle organization | 42.3077 | 4 | yes |
GO:0022607 | cellular component assembly | 42.3077 | 4 | yes |
GO:0031399 | regulation of protein modification process | 42.3077 | 6 | yes |
GO:0009893 | positive regulation of metabolic process | 38.4615 | 4 | no |
GO:0001932 | regulation of protein phosphorylation | 38.4615 | 7 | yes |
GO:0019220 | regulation of phosphate metabolic process | 38.4615 | 6 | yes |
GO:0042325 | regulation of phosphorylation | 38.4615 | 7 | yes |
GO:0051049 | regulation of transport | 38.4615 | 4 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 38.4615 | 5 | yes |
GO:0042981 | regulation of apoptotic process | 34.6154 | 5 | no |
GO:0043067 | regulation of programmed cell death | 34.6154 | 4 | no |
GO:0008104 | protein localization | 34.6154 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 34.6154 | 4 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 34.6154 | 5 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 34.6154 | 5 | yes |
GO:0034762 | regulation of transmembrane transport | 34.6154 | 4 | yes |
Disease
No data found.
All partners
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
5HT6R_HUMAN | [view interactions] | High throughput | no | yes |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AP2A_HUMAN | [view interactions] | High throughput | no | no |
ATX1L_HUMAN | [view interactions] | High throughput | no | no |
ATX7_HUMAN | [view interactions] | High throughput | no | no |
CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CCR8_HUMAN | [view interactions] | High throughput | no | no |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
CHIO_HUMAN | [view interactions] | High throughput | no | yes |
CLK1_HUMAN | [view interactions] | High throughput | no | yes |
CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DDR1_HUMAN | [view interactions] | High throughput | no | yes |
DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
FYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GHITM_HUMAN | [view interactions] | High throughput | no | yes |
GPAA1_HUMAN | [view interactions] | High throughput | no | yes |
GPI8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
LCK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
LITD1_HUMAN | [view interactions] | High throughput | no | no |
MFN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MPLKI_HUMAN | [view interactions] | High throughput | no | no |
MYC_HUMAN | [view interactions] | High throughput | no | yes |