Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

THY1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in THY1_HUMAN
GO:0000166 nucleotide binding 30.7692 4 no
GO:0017076 purine nucleotide binding 26.9231 5 no
GO:0043169 cation binding 26.9231 4 no
GO:0046872 metal ion binding 26.9231 5 no
GO:0019900 kinase binding 26.9231 4 yes
GO:0030554 adenyl nucleotide binding 23.0769 6 no
GO:0032555 purine ribonucleotide binding 23.0769 4 no
GO:0035639 purine ribonucleoside triphosphate binding 23.0769 4 no
GO:0043168 anion binding 23.0769 4 no
GO:0019901 protein kinase binding 15.3846 5 yes
GO:0030695 GTPase regulator activity 11.5385 4 yes
GO:0035091 phosphatidylinositol binding 11.5385 4 yes
GO:0005096 GTPase activator activity 11.5385 4 yes
GO:0034235 GPI anchor binding 7.6923 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in THY1_HUMAN
GO:0048523 negative regulation of cellular process 65.3846 4 yes
GO:0048522 positive regulation of cellular process 61.5385 4 yes
GO:0031323 regulation of cellular metabolic process 57.6923 4 yes
GO:0009966 regulation of signal transduction 53.8462 4 yes
GO:0010646 regulation of cell communication 53.8462 4 yes
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 yes
GO:0080090 regulation of primary metabolic process 50.0000 4 yes
GO:0051128 regulation of cellular component organization 46.1538 4 yes
GO:0051246 regulation of protein metabolic process 46.1538 5 yes
GO:0006996 organelle organization 42.3077 4 yes
GO:0022607 cellular component assembly 42.3077 4 yes
GO:0031399 regulation of protein modification process 42.3077 6 yes
GO:0009893 positive regulation of metabolic process 38.4615 4 no
GO:0001932 regulation of protein phosphorylation 38.4615 7 yes
GO:0019220 regulation of phosphate metabolic process 38.4615 6 yes
GO:0042325 regulation of phosphorylation 38.4615 7 yes
GO:0051049 regulation of transport 38.4615 4 yes
GO:0051174 regulation of phosphorus metabolic process 38.4615 5 yes
GO:0042981 regulation of apoptotic process 34.6154 5 no
GO:0043067 regulation of programmed cell death 34.6154 4 no
GO:0008104 protein localization 34.6154 4 yes
GO:0009892 negative regulation of metabolic process 34.6154 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 34.6154 5 yes
GO:0031324 negative regulation of cellular metabolic process 34.6154 5 yes
GO:0034762 regulation of transmembrane transport 34.6154 4 yes
GO:0043085 positive regulation of catalytic activity 34.6154 4 yes
GO:0048584 positive regulation of response to stimulus 34.6154 4 yes
GO:0051130 positive regulation of cellular component organization 34.6154 5 yes
GO:0009894 regulation of catabolic process 30.7692 4 no
GO:0007612 learning 30.7692 4 no
GO:0050890 cognition 30.7692 4 no
GO:0009968 negative regulation of signal transduction 30.7692 5 yes
GO:0010648 negative regulation of cell communication 30.7692 5 yes
GO:0023057 negative regulation of signaling 30.7692 4 yes
GO:0031344 regulation of cell projection organization 30.7692 5 yes
GO:0048585 negative regulation of response to stimulus 30.7692 4 yes
GO:0051240 positive regulation of multicellular organismal process 30.7692 4 yes
GO:0051338 regulation of transferase activity 30.7692 4 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 26.9231 6 yes
GO:0006811 monoatomic ion transport 26.9231 4 no
GO:0006812 monoatomic cation transport 26.9231 5 no
GO:0031329 regulation of cellular catabolic process 26.9231 5 no
GO:0030030 cell projection organization 26.9231 4 no
GO:0050804 modulation of chemical synaptic transmission 26.9231 5 no
GO:0099177 regulation of trans-synaptic signaling 26.9231 4 no
GO:0120036 plasma membrane bounded cell projection organization 26.9231 5 no
GO:0010647 positive regulation of cell communication 26.9231 5 no
GO:0023056 positive regulation of signaling 26.9231 4 no
GO:0031325 positive regulation of cellular metabolic process 26.9231 5 no
GO:0022603 regulation of anatomical structure morphogenesis 26.9231 4 yes
GO:0034330 cell junction organization 26.9231 4 yes
GO:0034765 regulation of monoatomic ion transmembrane transport 26.9231 5 yes
GO:0043269 regulation of monoatomic ion transport 26.9231 5 yes
GO:0043549 regulation of kinase activity 26.9231 5 yes
GO:0044087 regulation of cellular component biogenesis 26.9231 4 yes
GO:0045859 regulation of protein kinase activity 26.9231 6 yes
GO:0051129 negative regulation of cellular component organization 26.9231 5 yes
GO:0051924 regulation of calcium ion transport 23.0769 7 yes
GO:0072657 protein localization to membrane 23.0769 4 yes
GO:1903169 regulation of calcium ion transmembrane transport 23.0769 7 yes
GO:1904062 regulation of monoatomic cation transmembrane transport 23.0769 6 yes
GO:0098655 monoatomic cation transmembrane transport 23.0769 4 no
GO:0098662 inorganic cation transmembrane transport 23.0769 4 no
GO:0031175 neuron projection development 23.0769 6 no
GO:0043066 negative regulation of apoptotic process 23.0769 6 no
GO:0043069 negative regulation of programmed cell death 23.0769 5 no
GO:0048168 regulation of neuronal synaptic plasticity 23.0769 4 no
GO:0048169 regulation of long-term neuronal synaptic plasticity 23.0769 5 no
GO:0048812 neuron projection morphogenesis 23.0769 5 no
GO:0120039 plasma membrane bounded cell projection morphogenesis 23.0769 4 no
GO:1902531 regulation of intracellular signal transduction 23.0769 5 no
GO:0036211 protein modification process 23.0769 4 no
GO:0043412 macromolecule modification 23.0769 4 no
GO:0044057 regulation of system process 23.0769 4 no
GO:0098657 import into cell 23.0769 4 no
GO:0010604 positive regulation of macromolecule metabolic process 23.0769 5 no
GO:0051247 positive regulation of protein metabolic process 23.0769 6 no
GO:0009967 positive regulation of signal transduction 23.0769 5 no
GO:0010959 regulation of metal ion transport 23.0769 6 yes
GO:0010975 regulation of neuron projection development 23.0769 7 yes
GO:0031400 negative regulation of protein modification process 23.0769 7 yes
GO:0045595 regulation of cell differentiation 23.0769 4 yes
GO:0051248 negative regulation of protein metabolic process 23.0769 6 yes
GO:0051282 regulation of sequestering of calcium ion 23.0769 4 yes
GO:0051336 regulation of hydrolase activity 23.0769 4 yes
GO:0051345 positive regulation of hydrolase activity 19.2308 5 yes
GO:0060284 regulation of cell development 19.2308 5 yes
GO:0080134 regulation of response to stress 19.2308 4 yes
GO:2000145 regulation of cell motility 19.2308 4 yes
GO:0001933 negative regulation of protein phosphorylation 19.2308 8 yes
GO:0002684 positive regulation of immune system process 19.2308 4 yes
GO:0002694 regulation of leukocyte activation 19.2308 4 yes
GO:0007010 cytoskeleton organization 19.2308 5 yes
GO:0010563 negative regulation of phosphorus metabolic process 19.2308 6 yes
GO:0030334 regulation of cell migration 19.2308 5 yes
GO:0034329 cell junction assembly 19.2308 5 yes
GO:0034764 positive regulation of transmembrane transport 19.2308 5 yes
GO:0034767 positive regulation of monoatomic ion transmembrane transport 19.2308 6 yes
GO:0042326 negative regulation of phosphorylation 19.2308 8 yes
GO:0043113 receptor clustering 19.2308 5 yes
GO:0043270 positive regulation of monoatomic ion transport 19.2308 5 yes
GO:0044089 positive regulation of cellular component biogenesis 19.2308 5 yes
GO:0045596 negative regulation of cell differentiation 19.2308 5 yes
GO:0045936 negative regulation of phosphate metabolic process 19.2308 7 yes
GO:0050865 regulation of cell activation 19.2308 4 yes
GO:0051050 positive regulation of transport 19.2308 4 yes
GO:0051093 negative regulation of developmental process 19.2308 4 yes
GO:0051279 regulation of release of sequestered calcium ion into cytosol 19.2308 5 yes
GO:0051348 negative regulation of transferase activity 15.3846 5 yes
GO:0051928 positive regulation of calcium ion transport 15.3846 6 yes
GO:0051960 regulation of nervous system development 15.3846 5 yes
GO:0071900 regulation of protein serine/threonine kinase activity 15.3846 7 yes
GO:1901888 regulation of cell junction assembly 15.3846 5 yes
GO:1903037 regulation of leukocyte cell-cell adhesion 15.3846 6 yes
GO:1903039 positive regulation of leukocyte cell-cell adhesion 15.3846 7 yes
GO:1904064 positive regulation of cation transmembrane transport 15.3846 7 yes
GO:1904427 positive regulation of calcium ion transmembrane transport 15.3846 7 yes
GO:2000026 regulation of multicellular organismal development 15.3846 4 yes
GO:2000147 positive regulation of cell motility 15.3846 5 yes
GO:0002429 immune response-activating cell surface receptor signaling pathway 15.3846 4 yes
GO:0002696 positive regulation of leukocyte activation 15.3846 5 yes
GO:0002768 immune response-regulating cell surface receptor signaling pathway 15.3846 4 yes
GO:0006469 negative regulation of protein kinase activity 15.3846 7 yes
GO:0010721 negative regulation of cell development 15.3846 6 yes
GO:0022407 regulation of cell-cell adhesion 15.3846 5 yes
GO:0022409 positive regulation of cell-cell adhesion 15.3846 6 yes
GO:0030155 regulation of cell adhesion 15.3846 4 yes
GO:0030335 positive regulation of cell migration 15.3846 6 yes
GO:0031345 negative regulation of cell projection organization 15.3846 6 yes
GO:0033673 negative regulation of kinase activity 15.3846 6 yes
GO:0040017 positive regulation of locomotion 15.3846 4 yes
GO:0043086 negative regulation of catalytic activity 15.3846 4 yes
GO:0045785 positive regulation of cell adhesion 15.3846 5 yes
GO:0050767 regulation of neurogenesis 15.3846 6 yes
GO:0050776 regulation of immune response 15.3846 4 yes
GO:0050778 positive regulation of immune response 15.3846 5 yes
GO:0050851 antigen receptor-mediated signaling pathway 15.3846 5 yes
GO:0050852 T cell receptor signaling pathway 15.3846 6 yes
GO:0050863 regulation of T cell activation 15.3846 6 yes
GO:0050867 positive regulation of cell activation 15.3846 5 yes
GO:0050870 positive regulation of T cell activation 15.3846 7 yes
GO:0051241 negative regulation of multicellular organismal process 15.3846 4 yes
GO:0051249 regulation of lymphocyte activation 15.3846 5 yes
GO:0051251 positive regulation of lymphocyte activation 15.3846 6 yes
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 15.3846 6 yes
GO:0051961 negative regulation of nervous system development 11.5385 5 yes
GO:0150115 cell-substrate junction organization 11.5385 5 yes
GO:0002683 negative regulation of immune system process 11.5385 4 yes
GO:0002685 regulation of leukocyte migration 11.5385 4 yes
GO:0002687 positive regulation of leukocyte migration 11.5385 5 yes
GO:0007044 cell-substrate junction assembly 11.5385 6 yes
GO:0010977 negative regulation of neuron projection development 11.5385 7 yes
GO:0048041 focal adhesion assembly 11.5385 7 yes
GO:0050768 negative regulation of neurogenesis 11.5385 6 yes
GO:0050770 regulation of axonogenesis 11.5385 5 yes
GO:0050771 negative regulation of axonogenesis 11.5385 6 yes
GO:0050854 regulation of antigen receptor-mediated signaling pathway 11.5385 5 yes
GO:0050856 regulation of T cell receptor signaling pathway 11.5385 6 yes
GO:0051893 regulation of focal adhesion assembly 7.6923 7 yes
GO:0051894 positive regulation of focal adhesion assembly 7.6923 7 yes
GO:0070570 regulation of neuron projection regeneration 7.6923 4 yes
GO:0070571 negative regulation of neuron projection regeneration 7.6923 5 yes
GO:0080135 regulation of cellular response to stress 7.6923 4 yes
GO:0090109 regulation of cell-substrate junction assembly 7.6923 6 yes
GO:0150116 regulation of cell-substrate junction organization 7.6923 5 yes
GO:0150117 positive regulation of cell-substrate junction organization 7.6923 6 yes
GO:1901890 positive regulation of cell junction assembly 7.6923 6 yes
GO:2000146 negative regulation of cell motility 7.6923 5 yes
GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity 7.6923 8 yes
GO:0001952 regulation of cell-matrix adhesion 7.6923 6 yes
GO:0001954 positive regulation of cell-matrix adhesion 7.6923 7 yes
GO:0002691 regulation of cellular extravasation 7.6923 5 yes
GO:0002693 positive regulation of cellular extravasation 7.6923 6 yes
GO:0007229 integrin-mediated signaling pathway 7.6923 4 yes
GO:0010810 regulation of cell-substrate adhesion 7.6923 5 yes
GO:0010811 positive regulation of cell-substrate adhesion 7.6923 6 yes
GO:0030336 negative regulation of cell migration 7.6923 6 yes
GO:0034113 heterotypic cell-cell adhesion 7.6923 4 yes
GO:0040013 negative regulation of locomotion 7.6923 4 yes
GO:0042461 photoreceptor cell development 7.6923 5 yes
GO:0042462 eye photoreceptor cell development 7.6923 6 yes
GO:0043087 regulation of GTPase activity 7.6923 5 yes
GO:0043547 positive regulation of GTPase activity 7.6923 6 yes
GO:0046549 retinal cone cell development 7.6923 7 yes
GO:0048666 neuron development 7.6923 4 yes
GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 7.6923 5 yes
GO:0050860 negative regulation of T cell receptor signaling pathway 7.6923 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
LCK_HUMAN [view entry] [view interactions] Low throughput yes no
FYN_HUMAN [view entry] [view interactions] Low throughput yes no
THY1_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
AP2A_HUMAN [view interactions] High throughput no no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
SOST_HUMAN [view interactions] High throughput no no
HD_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
SYPH_HUMAN [view entry] [view interactions] High throughput yes yes
VATA_HUMAN [view entry] [view interactions] High throughput yes yes
DDR1_HUMAN [view interactions] High throughput no yes
LITD1_HUMAN [view interactions] High throughput no no
TX101_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
CAC1C_HUMAN [view entry] [view interactions] High throughput yes no
CCR8_HUMAN [view interactions] High throughput no no
5HT6R_HUMAN [view interactions] High throughput no yes
SOX4_HUMAN [view interactions] High throughput no yes
ATX7_HUMAN [view interactions] High throughput no no
ATX1L_HUMAN [view interactions] High throughput no no
STB5L_HUMAN [view interactions] High throughput no no
SEPR_HUMAN [view interactions] High throughput no yes
OXDA_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
TRPV1_HUMAN [view entry] [view interactions] High throughput yes no
TIA1_HUMAN [view interactions] High throughput no no
PIGU_HUMAN [view interactions] High throughput no no
GPAA1_HUMAN [view interactions] High throughput no yes
STEA3_HUMAN [view interactions] High throughput no yes
GPI8_HUMAN [view entry] [view interactions] High throughput yes no
MFN2_HUMAN [view entry] [view interactions] High throughput yes yes
GHITM_HUMAN [view interactions] High throughput no yes
PIGT_HUMAN [view interactions] High throughput no no
PIGS_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
UBP48_HUMAN [view interactions] High throughput no yes
CLK1_HUMAN [view interactions] High throughput no yes
UBC9_HUMAN [view entry] [view interactions] High throughput yes yes
SUGP1_HUMAN [view interactions] High throughput no yes
TIM44_HUMAN [view interactions] High throughput no yes
VDAC3_HUMAN [view entry] [view interactions] High throughput yes yes
TIAR_HUMAN [view interactions] High throughput no no
SCO2_HUMAN [view interactions] High throughput no no
SRC8_HUMAN [view entry] [view interactions] High throughput yes yes
SARNP_HUMAN [view interactions] High throughput no yes
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
RU1C_HUMAN [view interactions] High throughput no yes
ZFR_HUMAN [view interactions] High throughput no yes
UBE4B_HUMAN [view interactions] High throughput no yes
RM53_HUMAN [view interactions] High throughput no yes
VATE1_HUMAN [view entry] [view interactions] High throughput yes yes
NNTM_HUMAN [view entry] [view interactions] High throughput yes yes
MPLKI_HUMAN [view interactions] High throughput no no
UBAP2_HUMAN [view interactions] High throughput no yes
CYB5B_HUMAN [view entry] [view interactions] High throughput yes yes
SYJ2B_HUMAN [view interactions] High throughput no no
TOM22_HUMAN [view interactions] High throughput no yes
CHIO_HUMAN [view interactions] High throughput no yes
TGON2_HUMAN [view entry] [view interactions] High throughput yes yes