Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CALB1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3,5-cyclic nucleotide phosphodiesterase. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CALB1_HUMAN
GO:0043169 cation binding 23.0769 4 yes
GO:0046872 metal ion binding 23.0769 5 yes
GO:0001664 G protein-coupled receptor binding 23.0769 4 no
GO:0017124 SH3 domain binding 23.0769 4 no
GO:0035254 glutamate receptor binding 23.0769 4 no
GO:0035255 ionotropic glutamate receptor binding 23.0769 5 no
GO:0003723 RNA binding 23.0769 4 no
GO:0043168 anion binding 23.0769 4 no
GO:0046914 transition metal ion binding 15.3846 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in CALB1_HUMAN
GO:0010646 regulation of cell communication 61.5385 4 yes
GO:0048523 negative regulation of cellular process 61.5385 4 no
GO:0048522 positive regulation of cellular process 53.8462 4 no
GO:0051128 regulation of cellular component organization 53.8462 4 no
GO:0009966 regulation of signal transduction 46.1538 4 no
GO:0022607 cellular component assembly 46.1538 4 no
GO:0050804 modulation of chemical synaptic transmission 38.4615 5 yes
GO:0050890 cognition 38.4615 4 yes
GO:0099177 regulation of trans-synaptic signaling 38.4615 4 yes
GO:0009893 positive regulation of metabolic process 38.4615 4 no
GO:0010604 positive regulation of macromolecule metabolic process 38.4615 5 no
GO:0048585 negative regulation of response to stimulus 38.4615 4 no
GO:0051246 regulation of protein metabolic process 38.4615 5 no
GO:0051247 positive regulation of protein metabolic process 38.4615 6 no
GO:0060255 regulation of macromolecule metabolic process 38.4615 4 no
GO:0080090 regulation of primary metabolic process 38.4615 4 no
GO:0033043 regulation of organelle organization 38.4615 5 no
GO:0044087 regulation of cellular component biogenesis 38.4615 4 no
GO:0051094 positive regulation of developmental process 38.4615 4 no
GO:0071310 cellular response to organic substance 30.7692 4 yes
GO:0009968 negative regulation of signal transduction 30.7692 5 no
GO:0010648 negative regulation of cell communication 30.7692 5 no
GO:0023057 negative regulation of signaling 30.7692 4 no
GO:0043933 protein-containing complex organization 30.7692 4 no
GO:0065003 protein-containing complex assembly 30.7692 5 no
GO:1902531 regulation of intracellular signal transduction 30.7692 5 no
GO:0051049 regulation of transport 30.7692 4 no
GO:0010647 positive regulation of cell communication 30.7692 5 no
GO:0023056 positive regulation of signaling 30.7692 4 no
GO:0034330 cell junction organization 30.7692 4 no
GO:0050808 synapse organization 30.7692 5 no
GO:0051129 negative regulation of cellular component organization 30.7692 5 no
GO:0051493 regulation of cytoskeleton organization 30.7692 6 no
GO:1902903 regulation of supramolecular fiber organization 30.7692 5 no
GO:0009889 regulation of biosynthetic process 30.7692 4 no
GO:0009890 negative regulation of biosynthetic process 30.7692 5 no
GO:0009892 negative regulation of metabolic process 30.7692 4 no
GO:0009894 regulation of catabolic process 30.7692 4 no
GO:0010468 regulation of gene expression 30.7692 6 no
GO:0010556 regulation of macromolecule biosynthetic process 30.7692 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 30.7692 6 no
GO:0010605 negative regulation of macromolecule metabolic process 30.7692 5 no
GO:0010629 negative regulation of gene expression 30.7692 7 no
GO:0031323 regulation of cellular metabolic process 30.7692 4 no
GO:0031324 negative regulation of cellular metabolic process 30.7692 5 no
GO:0031326 regulation of cellular biosynthetic process 30.7692 5 no
GO:0031327 negative regulation of cellular biosynthetic process 30.7692 6 no
GO:0042127 regulation of cell population proliferation 30.7692 4 no
GO:0042981 regulation of apoptotic process 30.7692 5 no
GO:0043067 regulation of programmed cell death 30.7692 4 no
GO:0044089 positive regulation of cellular component biogenesis 30.7692 5 no
GO:0051130 positive regulation of cellular component organization 30.7692 5 no
GO:0051240 positive regulation of multicellular organismal process 30.7692 4 no
GO:0062197 cellular response to chemical stress 30.7692 4 no
GO:2000026 regulation of multicellular organismal development 30.7692 4 no
GO:0007613 memory 23.0769 4 yes
GO:0006996 organelle organization 23.0769 4 no
GO:1902532 negative regulation of intracellular signal transduction 23.0769 6 no
GO:0043085 positive regulation of catalytic activity 23.0769 4 no
GO:0008104 protein localization 23.0769 4 no
GO:0009967 positive regulation of signal transduction 23.0769 5 no
GO:0010639 negative regulation of organelle organization 23.0769 6 no
GO:0030030 cell projection organization 23.0769 4 no
GO:0031175 neuron projection development 23.0769 6 no
GO:0048584 positive regulation of response to stimulus 23.0769 4 no
GO:0120036 plasma membrane bounded cell projection organization 23.0769 5 no
GO:0001558 regulation of cell growth 23.0769 4 no
GO:0001817 regulation of cytokine production 23.0769 4 no
GO:0006796 phosphate-containing compound metabolic process 23.0769 4 no
GO:0008285 negative regulation of cell population proliferation 23.0769 5 no
GO:0009057 macromolecule catabolic process 23.0769 4 no
GO:0010638 positive regulation of organelle organization 23.0769 6 no
GO:0014070 response to organic cyclic compound 23.0769 4 no
GO:0016070 RNA metabolic process 23.0769 5 no
GO:0030162 regulation of proteolysis 23.0769 6 no
GO:0031110 regulation of microtubule polymerization or depolymerization 23.0769 6 no
GO:0031112 positive regulation of microtubule polymerization or depolymerization 23.0769 7 no
GO:0031113 regulation of microtubule polymerization 23.0769 6 no
GO:0031116 positive regulation of microtubule polymerization 23.0769 7 no
GO:0031325 positive regulation of cellular metabolic process 23.0769 5 no
GO:0031334 positive regulation of protein-containing complex assembly 23.0769 6 no
GO:0031399 regulation of protein modification process 23.0769 6 no
GO:0031400 negative regulation of protein modification process 23.0769 7 no
GO:0032101 regulation of response to external stimulus 23.0769 4 no
GO:0032271 regulation of protein polymerization 23.0769 6 no
GO:0032273 positive regulation of protein polymerization 23.0769 7 no
GO:0032886 regulation of microtubule-based process 23.0769 4 no
GO:0033993 response to lipid 23.0769 4 no
GO:0034599 cellular response to oxidative stress 23.0769 4 no
GO:0034605 cellular response to heat 23.0769 4 no
GO:0043254 regulation of protein-containing complex assembly 23.0769 5 no
GO:0045595 regulation of cell differentiation 23.0769 4 no
GO:0045597 positive regulation of cell differentiation 23.0769 5 no
GO:0045862 positive regulation of proteolysis 23.0769 7 no
GO:0048545 response to steroid hormone 23.0769 4 no
GO:0051248 negative regulation of protein metabolic process 23.0769 6 no
GO:0051495 positive regulation of cytoskeleton organization 23.0769 7 no
GO:0051726 regulation of cell cycle 23.0769 4 no
GO:0060284 regulation of cell development 23.0769 5 no
GO:0070507 regulation of microtubule cytoskeleton organization 23.0769 5 no
GO:0071407 cellular response to organic cyclic compound 23.0769 5 no
GO:0080134 regulation of response to stress 23.0769 4 no
GO:0090304 nucleic acid metabolic process 23.0769 4 no
GO:1902115 regulation of organelle assembly 23.0769 5 no
GO:1902905 positive regulation of supramolecular fiber organization 23.0769 6 no
GO:0007416 synapse assembly 23.0769 6 no
GO:0034329 cell junction assembly 23.0769 5 no
GO:0050807 regulation of synapse organization 23.0769 5 no
GO:0007616 long-term memory 15.3846 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NEMO_HUMAN [view interactions] Low throughput no yes
TRPV5_HUMAN [view interactions] Low throughput no no
TRPV6_HUMAN [view interactions] Low throughput no no
GRID2_HUMAN [view entry] [view interactions] Low throughput yes no
SHAN1_HUMAN [view entry] [view interactions] Low throughput yes yes
SHAN2_HUMAN [view entry] [view interactions] Low throughput yes yes
CASP3_HUMAN [view entry] [view interactions] Low throughput yes yes
RANB9_HUMAN [view entry] [view interactions] Low throughput yes yes
CAC1D_HUMAN [view entry] [view interactions] Low throughput yes yes
IMPA1_HUMAN [view entry] [view interactions] Low throughput yes yes
IQCB1_HUMAN [view interactions] High throughput no no
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
GRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
OTUD4_HUMAN [view interactions] High throughput no yes
DCE1_HUMAN [view entry] [view interactions] High throughput yes yes
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes