Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SNG3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

May play a role in regulated exocytosis. May indirectly regulate the activity of the plasma membrane dopamine transporter SLC6A3 and thereby regulate dopamine transport back from the synaptic cleft into the presynaptic terminal. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SNG3_HUMAN
GO:0043169 cation binding 36.3636 4 no
GO:0046872 metal ion binding 27.2727 5 no
GO:0042169 SH2 domain binding 18.1818 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in SNG3_HUMAN
GO:0010646 regulation of cell communication 63.6364 4 no
GO:0009966 regulation of signal transduction 54.5455 4 no
GO:0050804 modulation of chemical synaptic transmission 54.5455 5 no
GO:0099177 regulation of trans-synaptic signaling 54.5455 4 no
GO:0048523 negative regulation of cellular process 54.5455 4 no
GO:0031323 regulation of cellular metabolic process 54.5455 4 no
GO:0080090 regulation of primary metabolic process 54.5455 4 no
GO:0051049 regulation of transport 45.4545 4 yes
GO:0045595 regulation of cell differentiation 45.4545 4 no
GO:0060255 regulation of macromolecule metabolic process 45.4545 4 no
GO:1902531 regulation of intracellular signal transduction 45.4545 5 no
GO:0030334 regulation of cell migration 36.3636 5 no
GO:0032101 regulation of response to external stimulus 36.3636 4 no
GO:2000145 regulation of cell motility 36.3636 4 no
GO:0006996 organelle organization 36.3636 4 no
GO:0044087 regulation of cellular component biogenesis 36.3636 4 no
GO:0051128 regulation of cellular component organization 36.3636 4 no
GO:0009889 regulation of biosynthetic process 36.3636 4 no
GO:0009892 negative regulation of metabolic process 36.3636 4 no
GO:0009894 regulation of catabolic process 36.3636 4 no
GO:0010468 regulation of gene expression 36.3636 6 no
GO:0010556 regulation of macromolecule biosynthetic process 36.3636 5 no
GO:0010605 negative regulation of macromolecule metabolic process 36.3636 5 no
GO:0019220 regulation of phosphate metabolic process 36.3636 6 no
GO:0031324 negative regulation of cellular metabolic process 36.3636 5 no
GO:0031326 regulation of cellular biosynthetic process 36.3636 5 no
GO:0031399 regulation of protein modification process 36.3636 6 no
GO:0042325 regulation of phosphorylation 36.3636 7 no
GO:0043549 regulation of kinase activity 36.3636 5 no
GO:0048522 positive regulation of cellular process 36.3636 4 no
GO:0051174 regulation of phosphorus metabolic process 36.3636 5 no
GO:0051240 positive regulation of multicellular organismal process 36.3636 4 no
GO:0051246 regulation of protein metabolic process 36.3636 5 no
GO:0051338 regulation of transferase activity 36.3636 4 no
GO:0046903 secretion 27.2727 4 yes
GO:0051588 regulation of neurotransmitter transport 27.2727 5 yes
GO:0002685 regulation of leukocyte migration 27.2727 4 no
GO:0048168 regulation of neuronal synaptic plasticity 27.2727 4 no
GO:0048169 regulation of long-term neuronal synaptic plasticity 27.2727 5 no
GO:0061024 membrane organization 27.2727 4 no
GO:0071310 cellular response to organic substance 27.2727 4 no
GO:0098657 import into cell 27.2727 4 no
GO:0001932 regulation of protein phosphorylation 27.2727 7 no
GO:0002684 positive regulation of immune system process 27.2727 4 no
GO:0009967 positive regulation of signal transduction 27.2727 5 no
GO:0010243 response to organonitrogen compound 27.2727 4 no
GO:0010647 positive regulation of cell communication 27.2727 5 no
GO:0022607 cellular component assembly 27.2727 4 no
GO:0023056 positive regulation of signaling 27.2727 4 no
GO:0031329 regulation of cellular catabolic process 27.2727 5 no
GO:0034329 cell junction assembly 27.2727 5 no
GO:0034330 cell junction organization 27.2727 4 no
GO:0036211 protein modification process 27.2727 4 no
GO:0042127 regulation of cell population proliferation 27.2727 4 no
GO:0043408 regulation of MAPK cascade 27.2727 6 no
GO:0043412 macromolecule modification 27.2727 4 no
GO:0045859 regulation of protein kinase activity 27.2727 6 no
GO:0048584 positive regulation of response to stimulus 27.2727 4 no
GO:0048638 regulation of developmental growth 27.2727 4 no
GO:0050890 cognition 27.2727 4 no
GO:0051093 negative regulation of developmental process 27.2727 4 no
GO:0070372 regulation of ERK1 and ERK2 cascade 27.2727 7 no
GO:0097435 supramolecular fiber organization 27.2727 4 no
GO:1901701 cellular response to oxygen-containing compound 27.2727 4 no
GO:0010563 negative regulation of phosphorus metabolic process 27.2727 6 no
GO:0022603 regulation of anatomical structure morphogenesis 27.2727 4 no
GO:0031400 negative regulation of protein modification process 27.2727 7 no
GO:0033673 negative regulation of kinase activity 27.2727 6 no
GO:0042326 negative regulation of phosphorylation 27.2727 8 no
GO:0043086 negative regulation of catalytic activity 27.2727 4 no
GO:0045936 negative regulation of phosphate metabolic process 27.2727 7 no
GO:0048585 negative regulation of response to stimulus 27.2727 4 no
GO:0051248 negative regulation of protein metabolic process 27.2727 6 no
GO:0051348 negative regulation of transferase activity 27.2727 5 no
GO:0060284 regulation of cell development 27.2727 5 no
GO:2000026 regulation of multicellular organismal development 27.2727 4 no
GO:0051094 positive regulation of developmental process 27.2727 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SYPH_HUMAN [view entry] [view interactions] Low throughput yes yes
SC6A3_HUMAN [view entry] [view interactions] Low throughput yes yes
S39A9_HUMAN [view interactions] High throughput no yes
VATA_HUMAN [view entry] [view interactions] High throughput yes yes
SPG21_HUMAN [view interactions] High throughput no yes
TTPA_HUMAN [view interactions] High throughput no no
SHLB1_HUMAN [view interactions] High throughput no yes
ECHP_HUMAN [view interactions] High throughput no no
EM55_HUMAN [view entry] [view interactions] High throughput yes no
ARFP1_HUMAN [view interactions] High throughput no no
DCE2_HUMAN [view interactions] High throughput no yes
HSBPL_HUMAN [view interactions] High throughput no yes
ACSF2_HUMAN [view interactions] High throughput no no
PLIN3_HUMAN [view interactions] High throughput no yes
MIDN_HUMAN [view interactions] High throughput no no
PNKP_HUMAN [view interactions] High throughput no yes
KPCA_HUMAN [view entry] [view interactions] High throughput yes yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
KAT5_HUMAN [view interactions] High throughput no yes
IRF3_HUMAN [view interactions] High throughput no yes
NDRG4_HUMAN [view interactions] High throughput no no
GLP1R_HUMAN [view interactions] High throughput no no
AT1B4_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
ESR2_HUMAN [view interactions] High throughput no no
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
NKG2C_HUMAN [view interactions] High throughput no no
NKG2A_HUMAN [view interactions] High throughput no no
MAS_HUMAN [view interactions] High throughput no no
RUSF1_HUMAN [view interactions] High throughput no yes
TMM59_HUMAN [view interactions] High throughput no yes
GPR12_HUMAN [view interactions] High throughput no no
PRRT2_HUMAN [view entry] [view interactions] High throughput yes no
NF1_HUMAN [view entry] [view interactions] High throughput yes no
A4_HUMAN [view entry] [view interactions] High throughput yes yes