Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

LRRT4_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

May play a role in the development and maintenance of the vertebrate nervous system. Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation . [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in LRRT4_HUMAN
GO:0046872 metal ion binding 35.7143 4 no
GO:0097109 neuroligin family protein binding 28.5714 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in LRRT4_HUMAN
GO:0010646 regulation of cell communication 50.0000 4 no
GO:0022607 cellular component assembly 50.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 42.8571 4 no
GO:0009966 regulation of signal transduction 42.8571 4 no
GO:0048522 positive regulation of cellular process 42.8571 4 no
GO:0051094 positive regulation of developmental process 42.8571 4 no
GO:0008104 protein localization 42.8571 4 no
GO:2000026 regulation of multicellular organismal development 42.8571 4 no
GO:0051128 regulation of cellular component organization 42.8571 4 no
GO:0031323 regulation of cellular metabolic process 35.7143 4 no
GO:0051171 regulation of nitrogen compound metabolic process 35.7143 4 no
GO:0080090 regulation of primary metabolic process 35.7143 4 no
GO:0048523 negative regulation of cellular process 35.7143 4 no
GO:0072657 protein localization to membrane 35.7143 4 no
GO:0030030 cell projection organization 35.7143 4 no
GO:0031175 neuron projection development 35.7143 6 no
GO:0050890 cognition 35.7143 4 no
GO:0120036 plasma membrane bounded cell projection organization 35.7143 5 no
GO:0010648 negative regulation of cell communication 28.5714 5 no
GO:0023057 negative regulation of signaling 28.5714 4 no
GO:0045595 regulation of cell differentiation 28.5714 4 no
GO:0006996 organelle organization 28.5714 4 no
GO:0009893 positive regulation of metabolic process 28.5714 4 no
GO:0010604 positive regulation of macromolecule metabolic process 28.5714 5 no
GO:0031325 positive regulation of cellular metabolic process 28.5714 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 28.5714 5 no
GO:0051240 positive regulation of multicellular organismal process 28.5714 4 no
GO:0044087 regulation of cellular component biogenesis 28.5714 4 no
GO:1901888 regulation of cell junction assembly 28.5714 5 no
GO:0007268 chemical synaptic transmission 28.5714 6 no
GO:0007612 learning 28.5714 4 no
GO:0051130 positive regulation of cellular component organization 28.5714 5 no
GO:0098916 anterograde trans-synaptic signaling 28.5714 5 no
GO:0099537 trans-synaptic signaling 28.5714 4 no
GO:0051960 regulation of nervous system development 28.5714 5 no
GO:0007411 axon guidance 28.5714 8 no
GO:0097485 neuron projection guidance 28.5714 7 no
GO:0010468 regulation of gene expression 21.4286 5 no
GO:0009968 negative regulation of signal transduction 21.4286 5 no
GO:0032880 regulation of protein localization 21.4286 5 no
GO:0045597 positive regulation of cell differentiation 21.4286 5 no
GO:0048585 negative regulation of response to stimulus 21.4286 4 no
GO:0060341 regulation of cellular localization 21.4286 4 no
GO:1905475 regulation of protein localization to membrane 21.4286 6 no
GO:0030155 regulation of cell adhesion 21.4286 4 no
GO:0033365 protein localization to organelle 21.4286 5 no
GO:0061024 membrane organization 21.4286 4 no
GO:0050807 regulation of synapse organization 21.4286 5 no
GO:0051963 regulation of synapse assembly 21.4286 6 no
GO:0009967 positive regulation of signal transduction 21.4286 5 no
GO:0010647 positive regulation of cell communication 21.4286 5 no
GO:0022603 regulation of anatomical structure morphogenesis 21.4286 4 no
GO:0023056 positive regulation of signaling 21.4286 4 no
GO:0031344 regulation of cell projection organization 21.4286 5 no
GO:0035418 protein localization to synapse 21.4286 6 no
GO:0043113 receptor clustering 21.4286 5 no
GO:0048584 positive regulation of response to stimulus 21.4286 4 no
GO:0050804 modulation of chemical synaptic transmission 21.4286 5 no
GO:0051129 negative regulation of cellular component organization 21.4286 5 no
GO:0051246 regulation of protein metabolic process 21.4286 5 no
GO:0051247 positive regulation of protein metabolic process 21.4286 6 no
GO:0099177 regulation of trans-synaptic signaling 21.4286 4 no
GO:1902414 protein localization to cell junction 21.4286 5 no
GO:0044089 positive regulation of cellular component biogenesis 21.4286 5 no
GO:0051962 positive regulation of nervous system development 21.4286 5 no
GO:1901890 positive regulation of cell junction assembly 21.4286 6 no
GO:0007158 neuron cell-cell adhesion 21.4286 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
PTPRS_HUMAN [view entry] [view interactions] Low throughput yes no
GRIA1_HUMAN [view entry] [view interactions] Low throughput yes yes
PILRA_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
DX39A_HUMAN [view interactions] High throughput no yes
CD11B_HUMAN [view interactions] High throughput no yes
AFF4_HUMAN [view interactions] High throughput no yes
CNPY4_HUMAN [view interactions] High throughput no yes
CHRC1_HUMAN [view interactions] High throughput no no
CXXC1_HUMAN [view interactions] High throughput no yes
CENPB_HUMAN [view interactions] High throughput no yes
AP3B1_HUMAN [view entry] [view interactions] High throughput yes yes
BLK_HUMAN [view interactions] High throughput no no
TGBR3_HUMAN [view interactions] High throughput no yes
GPC4_HUMAN [view entry] [view interactions] High throughput yes yes
UBP34_HUMAN [view interactions] High throughput no yes
LAMA5_HUMAN [view entry] [view interactions] High throughput yes no
SETD2_HUMAN [view interactions] High throughput no yes
ZN426_HUMAN [view interactions] High throughput no yes
CCNL2_HUMAN [view interactions] High throughput no yes
P4R3A_HUMAN [view interactions] High throughput no yes
NID2_HUMAN [view interactions] High throughput no yes
CNPY3_HUMAN [view interactions] High throughput no yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
LRRT3_HUMAN [view entry] [view interactions] High throughput yes no
GPC1_HUMAN [view entry] [view interactions] High throughput yes no
GPC3_HUMAN [view interactions] High throughput no no
SGPL1_HUMAN [view interactions] High throughput no yes
NRX2A_HUMAN [view entry] [view interactions] Computational yes no
NRX3A_HUMAN [view entry] [view interactions] Computational yes yes
NRX1A_HUMAN [view entry] [view interactions] Computational yes no