LRRT4_HUMAN
Evidence for PS localization
Functions
May play a role in the development and maintenance of the vertebrate nervous system. Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation . [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in LRRT4_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 27.2727 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in LRRT4_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 63.6364 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 54.5455 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 54.5455 | 4 | no |
| GO:0010646 | regulation of cell communication | 54.5455 | 4 | no |
| GO:0022607 | cellular component assembly | 54.5455 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 45.4545 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 45.4545 | 5 | no |
| GO:0051094 | positive regulation of developmental process | 45.4545 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 45.4545 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 45.4545 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 45.4545 | 4 | no |
| GO:0009966 | regulation of signal transduction | 45.4545 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 45.4545 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 36.3636 | 4 | no |
| GO:1901888 | regulation of cell junction assembly | 36.3636 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 36.3636 | 4 | no |
| GO:0010468 | regulation of gene expression | 36.3636 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 36.3636 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 36.3636 | 5 | no |
| GO:0008104 | protein localization | 36.3636 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 36.3636 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 36.3636 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 36.3636 | 5 | no |
| GO:0023057 | negative regulation of signaling | 36.3636 | 4 | no |
| GO:0050807 | regulation of synapse organization | 27.2727 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 27.2727 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 27.2727 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 27.2727 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 27.2727 | 6 | no |
| GO:0051960 | regulation of nervous system development | 27.2727 | 5 | no |
| GO:0051963 | regulation of synapse assembly | 27.2727 | 6 | no |
| GO:0006996 | organelle organization | 27.2727 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 27.2727 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 27.2727 | 4 | no |
| GO:0023056 | positive regulation of signaling | 27.2727 | 4 | no |
| GO:0030030 | cell projection organization | 27.2727 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 27.2727 | 5 | no |
| GO:0033365 | protein localization to organelle | 27.2727 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 27.2727 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 27.2727 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 27.2727 | 5 | no |
| GO:0072657 | protein localization to membrane | 27.2727 | 4 | no |
| GO:0099173 | postsynapse organization | 27.2727 | 4 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 27.2727 | 4 | no |
| GO:0099536 | synaptic signaling | 27.2727 | 4 | no |
| GO:0099537 | trans-synaptic signaling | 27.2727 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 27.2727 | 5 | no |
| GO:0030155 | regulation of cell adhesion | 27.2727 | 4 | no |
| GO:0032101 | regulation of response to external stimulus | 27.2727 | 4 | no |
| GO:0045597 | positive regulation of cell differentiation | 27.2727 | 5 | no |
| GO:0060284 | regulation of cell development | 27.2727 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 27.2727 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 27.2727 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTPRS_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRIA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PILRA_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| CD11B_HUMAN | [view interactions] | High throughput | no | yes |
| AFF4_HUMAN | [view interactions] | High throughput | no | yes |
| CNPY4_HUMAN | [view interactions] | High throughput | no | yes |
| CHRC1_HUMAN | [view interactions] | High throughput | no | no |
| CXXC1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPB_HUMAN | [view interactions] | High throughput | no | yes |
| AP3B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BLK_HUMAN | [view interactions] | High throughput | no | no |
| TGBR3_HUMAN | [view interactions] | High throughput | no | yes |
| GPC4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP34_HUMAN | [view interactions] | High throughput | no | yes |
| LAMA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SETD2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN426_HUMAN | [view interactions] | High throughput | no | yes |
| CCNL2_HUMAN | [view interactions] | High throughput | no | yes |
| P4R3A_HUMAN | [view interactions] | High throughput | no | yes |
| NID2_HUMAN | [view interactions] | High throughput | no | yes |
| CNPY3_HUMAN | [view interactions] | High throughput | no | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRT3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GPC3_HUMAN | [view interactions] | High throughput | no | no |
| SGPL1_HUMAN | [view interactions] | High throughput | no | yes |
| SSR3_HUMAN | [view interactions] | High throughput | no | yes |