AL1L1_HUMAN
Evidence for PS localization
Functions
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in AL1L1_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 25.0000 | 4 | no |
| GO:0017076 | purine nucleotide binding | 25.0000 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 25.0000 | 6 | no |
| GO:0032555 | purine ribonucleotide binding | 25.0000 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 25.0000 | 5 | no |
| GO:0043168 | anion binding | 25.0000 | 4 | no |
| GO:0003723 | RNA binding | 20.8333 | 4 | no |
| GO:0005524 | ATP binding | 20.8333 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 20.8333 | 4 | no |
| GO:0019900 | kinase binding | 20.8333 | 4 | no |
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | 12.5000 | 4 | yes |
| GO:0004029 | aldehyde dehydrogenase (NAD+) activity | 8.3333 | 6 | yes |
| GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity | 8.3333 | 5 | yes |
| GO:0016155 | formyltetrahydrofolate dehydrogenase activity | 8.3333 | 5 | yes |
| GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor | 8.3333 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in AL1L1_HUMAN |
|---|---|---|---|---|
| GO:0031323 | regulation of cellular metabolic process | 45.8333 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 45.8333 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 45.8333 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 41.6667 | 5 | no |
| GO:0048522 | positive regulation of cellular process | 41.6667 | 4 | no |
| GO:1901565 | organonitrogen compound catabolic process | 37.5000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 37.5000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 33.3333 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 33.3333 | 4 | no |
| GO:0022607 | cellular component assembly | 29.1667 | 4 | no |
| GO:0009894 | regulation of catabolic process | 29.1667 | 4 | no |
| GO:0009966 | regulation of signal transduction | 29.1667 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.1667 | 5 | no |
| GO:0010646 | regulation of cell communication | 29.1667 | 4 | no |
| GO:0031399 | regulation of protein modification process | 25.0000 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 25.0000 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 25.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 25.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 25.0000 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.0000 | 5 | no |
| GO:0030162 | regulation of proteolysis | 25.0000 | 6 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 25.0000 | 5 | no |
| GO:0042176 | regulation of protein catabolic process | 25.0000 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 25.0000 | 5 | no |
| GO:0009057 | macromolecule catabolic process | 25.0000 | 4 | no |
| GO:0030163 | protein catabolic process | 25.0000 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 25.0000 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 25.0000 | 6 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 20.8333 | 4 | yes |
| GO:0008104 | protein localization | 20.8333 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 20.8333 | 6 | no |
| GO:0043066 | negative regulation of apoptotic process | 20.8333 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 20.8333 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 20.8333 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 20.8333 | 5 | no |
| GO:0036211 | protein modification process | 20.8333 | 4 | no |
| GO:0043412 | macromolecule modification | 20.8333 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 20.8333 | 5 | no |
| GO:0032880 | regulation of protein localization | 20.8333 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 20.8333 | 5 | no |
| GO:0060341 | regulation of cellular localization | 20.8333 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 20.8333 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 20.8333 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 20.8333 | 5 | no |
| GO:0023057 | negative regulation of signaling | 20.8333 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 20.8333 | 4 | no |
| GO:0006508 | proteolysis | 20.8333 | 4 | no |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 20.8333 | 7 | no |
| GO:0010498 | proteasomal protein catabolic process | 20.8333 | 5 | no |
| GO:0019941 | modification-dependent protein catabolic process | 20.8333 | 6 | no |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 20.8333 | 6 | no |
| GO:0043632 | modification-dependent macromolecule catabolic process | 20.8333 | 5 | no |
| GO:0051603 | proteolysis involved in protein catabolic process | 20.8333 | 5 | no |
| GO:0006163 | purine nucleotide metabolic process | 16.6667 | 5 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 16.6667 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 16.6667 | 5 | yes |
| GO:0016054 | organic acid catabolic process | 16.6667 | 4 | yes |
| GO:0019752 | carboxylic acid metabolic process | 16.6667 | 5 | yes |
| GO:0043436 | oxoacid metabolic process | 16.6667 | 4 | yes |
| GO:0046395 | carboxylic acid catabolic process | 16.6667 | 5 | yes |
| GO:0072521 | purine-containing compound metabolic process | 16.6667 | 4 | yes |
| GO:0006739 | NADP metabolic process | 8.3333 | 6 | yes |
| GO:0006740 | NADPH regeneration | 8.3333 | 4 | yes |
| GO:0006760 | folic acid-containing compound metabolic process | 8.3333 | 4 | yes |
| GO:0009256 | 10-formyltetrahydrofolate metabolic process | 8.3333 | 6 | yes |
| GO:0009258 | 10-formyltetrahydrofolate catabolic process | 8.3333 | 6 | yes |
| GO:0009397 | folic acid-containing compound catabolic process | 8.3333 | 5 | yes |
| GO:0019362 | pyridine nucleotide metabolic process | 8.3333 | 5 | yes |
| GO:0042219 | cellular modified amino acid catabolic process | 8.3333 | 4 | yes |
| GO:0042558 | pteridine-containing compound metabolic process | 8.3333 | 4 | yes |
| GO:0042560 | pteridine-containing compound catabolic process | 8.3333 | 5 | yes |
| GO:0043648 | dicarboxylic acid metabolic process | 8.3333 | 6 | yes |
| GO:0043649 | dicarboxylic acid catabolic process | 8.3333 | 6 | yes |
| GO:0046496 | nicotinamide nucleotide metabolic process | 8.3333 | 6 | yes |
| GO:0046653 | tetrahydrofolate metabolic process | 8.3333 | 5 | yes |
| GO:0072524 | pyridine-containing compound metabolic process | 8.3333 | 4 | yes |
| GO:1901361 | organic cyclic compound catabolic process | 8.3333 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RS30_HUMAN | [view interactions] | Low throughput | no | yes |
| CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AL1L1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SIR4_HUMAN | [view interactions] | High throughput | no | yes |
| AL1L2_HUMAN | [view interactions] | High throughput | no | yes |
| ABHDB_HUMAN | [view interactions] | High throughput | no | yes |
| SDHF3_HUMAN | [view interactions] | High throughput | no | yes |
| ADCK1_HUMAN | [view interactions] | High throughput | no | no |
| PPA6_HUMAN | [view interactions] | High throughput | no | no |
| COQ8A_HUMAN | [view interactions] | High throughput | no | no |
| MIC27_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADCK5_HUMAN | [view interactions] | High throughput | no | yes |
| COQ8B_HUMAN | [view interactions] | High throughput | no | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| BOLA1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUF8_HUMAN | [view interactions] | High throughput | no | no |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| MAIP1_HUMAN | [view interactions] | High throughput | no | yes |
| CHCH1_HUMAN | [view interactions] | High throughput | no | yes |
| MIX23_HUMAN | [view interactions] | High throughput | no | yes |
| FMC1_HUMAN | [view interactions] | High throughput | no | no |
| SUCHY_HUMAN | [view interactions] | High throughput | no | yes |
| MRES1_HUMAN | [view interactions] | High throughput | no | yes |
| CHC10_HUMAN | [view interactions] | High throughput | no | yes |
| COQ4_HUMAN | [view interactions] | High throughput | no | yes |
| COQ3_HUMAN | [view interactions] | High throughput | no | no |
| COQ2_HUMAN | [view interactions] | High throughput | no | yes |
| COQ5_HUMAN | [view interactions] | High throughput | no | yes |
| CQ10A_HUMAN | [view interactions] | High throughput | no | no |
| CISD3_HUMAN | [view interactions] | High throughput | no | yes |
| CHCH2_HUMAN | [view interactions] | High throughput | no | yes |
| CQ10B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COQ6_HUMAN | [view interactions] | High throughput | no | yes |
| COQ7_HUMAN | [view interactions] | High throughput | no | yes |
| COQ9_HUMAN | [view interactions] | High throughput | no | yes |
| CX6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| F136A_HUMAN | [view interactions] | High throughput | no | yes |
| GPAT1_HUMAN | [view interactions] | High throughput | no | no |
| HOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| IVD_HUMAN | [view interactions] | High throughput | no | yes |
| AFG1L_HUMAN | [view interactions] | High throughput | no | yes |
| LACTB_HUMAN | [view interactions] | High throughput | no | yes |
| LYRM1_HUMAN | [view interactions] | High throughput | no | no |
| LYRM2_HUMAN | [view interactions] | High throughput | no | no |
| LYRM4_HUMAN | [view interactions] | High throughput | no | yes |
| ETFR1_HUMAN | [view interactions] | High throughput | no | no |
| MCCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NIT1_HUMAN | [view interactions] | High throughput | no | yes |
| NDKM_HUMAN | [view interactions] | High throughput | no | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| OPA3_HUMAN | [view interactions] | High throughput | no | yes |
| SCOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCOT2_HUMAN | [view interactions] | High throughput | no | no |
| NDUF4_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAK5_HUMAN | [view interactions] | High throughput | no | yes |
| TAM41_HUMAN | [view interactions] | High throughput | no | no |
| SPRY4_HUMAN | [view interactions] | High throughput | no | yes |
| PHIPL_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1K_HUMAN | [view interactions] | High throughput | no | yes |
| PPTC7_HUMAN | [view interactions] | High throughput | no | yes |
| PPCEL_HUMAN | [view interactions] | High throughput | no | yes |
| PRS35_HUMAN | [view interactions] | High throughput | no | no |
| PTPM1_HUMAN | [view interactions] | High throughput | no | yes |
| PLD3B_HUMAN | [view interactions] | High throughput | no | yes |
| SPT20_HUMAN | [view interactions] | High throughput | no | yes |
| XPP3_HUMAN | [view interactions] | High throughput | no | yes |
| ADCK2_HUMAN | [view interactions] | High throughput | no | yes |
| ECI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYRM7_HUMAN | [view interactions] | High throughput | no | yes |
| NDUF5_HUMAN | [view interactions] | High throughput | no | yes |
| MIC13_HUMAN | [view interactions] | High throughput | no | yes |
| TRUB2_HUMAN | [view interactions] | High throughput | no | yes |
| CC062_HUMAN | [view interactions] | High throughput | no | no |
| DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
| F90A1_HUMAN | [view interactions] | High throughput | no | no |
| JAZF1_HUMAN | [view interactions] | High throughput | no | yes |
| SET_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APBP2_HUMAN | [view interactions] | High throughput | no | yes |
| DAPLE_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| UBP47_HUMAN | [view interactions] | High throughput | no | yes |
| PRS6B_HUMAN | [view interactions] | High throughput | no | yes |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS7_HUMAN | [view interactions] | High throughput | no | yes |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS8_HUMAN | [view interactions] | High throughput | no | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| PRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| CLUA1_HUMAN | [view interactions] | High throughput | no | yes |
| PLPL2_HUMAN | [view interactions] | High throughput | no | no |
| GTR5_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| HAPR1_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GDIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MSH2_HUMAN | [view interactions] | High throughput | no | yes |