Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RIMB2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in RIMB2_HUMAN
GO:0043169 cation binding 50.0000 4 no
GO:0046872 metal ion binding 50.0000 5 no
GO:0019900 kinase binding 33.3333 4 no
GO:0019901 protein kinase binding 33.3333 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in RIMB2_HUMAN
GO:0010646 regulation of cell communication 66.6667 4 no
GO:0031323 regulation of cellular metabolic process 66.6667 4 no
GO:0048522 positive regulation of cellular process 66.6667 4 no
GO:0060255 regulation of macromolecule metabolic process 66.6667 4 no
GO:0006796 phosphate-containing compound metabolic process 50.0000 4 no
GO:0009966 regulation of signal transduction 50.0000 4 no
GO:0036211 protein modification process 50.0000 4 no
GO:0043412 macromolecule modification 50.0000 4 no
GO:0048584 positive regulation of response to stimulus 50.0000 4 no
GO:0051128 regulation of cellular component organization 50.0000 4 no
GO:0051246 regulation of protein metabolic process 50.0000 5 no
GO:0080090 regulation of primary metabolic process 50.0000 4 no
GO:0007268 chemical synaptic transmission 33.3333 7 yes
GO:0098916 anterograde trans-synaptic signaling 33.3333 6 yes
GO:0099536 synaptic signaling 33.3333 4 yes
GO:0099537 trans-synaptic signaling 33.3333 5 yes
GO:0010243 response to organonitrogen compound 33.3333 4 no
GO:0001932 regulation of protein phosphorylation 33.3333 7 no
GO:0001934 positive regulation of protein phosphorylation 33.3333 8 no
GO:0006468 protein phosphorylation 33.3333 5 no
GO:0006996 organelle organization 33.3333 4 no
GO:0007010 cytoskeleton organization 33.3333 5 no
GO:0009893 positive regulation of metabolic process 33.3333 4 no
GO:0009967 positive regulation of signal transduction 33.3333 5 no
GO:0010562 positive regulation of phosphorus metabolic process 33.3333 6 no
GO:0010604 positive regulation of macromolecule metabolic process 33.3333 5 no
GO:0010647 positive regulation of cell communication 33.3333 5 no
GO:0010975 regulation of neuron projection development 33.3333 7 no
GO:0016310 phosphorylation 33.3333 5 no
GO:0019220 regulation of phosphate metabolic process 33.3333 6 no
GO:0022603 regulation of anatomical structure morphogenesis 33.3333 4 no
GO:0022607 cellular component assembly 33.3333 4 no
GO:0023056 positive regulation of signaling 33.3333 4 no
GO:0031325 positive regulation of cellular metabolic process 33.3333 5 no
GO:0031344 regulation of cell projection organization 33.3333 5 no
GO:0031399 regulation of protein modification process 33.3333 6 no
GO:0031401 positive regulation of protein modification process 33.3333 7 no
GO:0042325 regulation of phosphorylation 33.3333 7 no
GO:0042327 positive regulation of phosphorylation 33.3333 8 no
GO:0045937 positive regulation of phosphate metabolic process 33.3333 7 no
GO:0051174 regulation of phosphorus metabolic process 33.3333 5 no
GO:0051247 positive regulation of protein metabolic process 33.3333 6 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 33.3333 6 no
GO:0009889 regulation of biosynthetic process 33.3333 4 no
GO:0010468 regulation of gene expression 33.3333 6 no
GO:0010556 regulation of macromolecule biosynthetic process 33.3333 5 no
GO:0022411 cellular component disassembly 33.3333 4 no
GO:0031326 regulation of cellular biosynthetic process 33.3333 5 no
GO:0043933 protein-containing complex organization 33.3333 4 no
GO:0009892 negative regulation of metabolic process 33.3333 4 no
GO:0010605 negative regulation of macromolecule metabolic process 33.3333 5 no
GO:0030334 regulation of cell migration 33.3333 5 no
GO:0031324 negative regulation of cellular metabolic process 33.3333 5 no
GO:0048523 negative regulation of cellular process 33.3333 4 no
GO:0050807 regulation of synapse organization 33.3333 5 no
GO:0099175 regulation of postsynapse organization 33.3333 6 no
GO:2000145 regulation of cell motility 33.3333 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CAC1A_HUMAN [view entry] [view interactions] Low throughput yes no
CAC1B_HUMAN [view interactions] Low throughput no yes
ADA10_HUMAN [view entry] [view interactions] High throughput yes yes
ADA12_HUMAN [view interactions] High throughput no no
UBP3_HUMAN [view interactions] High throughput no no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
NAA10_HUMAN [view interactions] High throughput no yes
KAT6A_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
SPPL3_HUMAN [view interactions] High throughput no no