Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PGCB_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PGCB_HUMAN
GO:0043169 cation binding 40.0000 4 no
GO:0046872 metal ion binding 40.0000 5 no
GO:0000166 nucleotide binding 30.0000 4 no
GO:0005524 ATP binding 30.0000 5 no
GO:0017076 purine nucleotide binding 30.0000 5 no
GO:0030554 adenyl nucleotide binding 30.0000 6 no
GO:0032555 purine ribonucleotide binding 30.0000 4 no
GO:0032559 adenyl ribonucleotide binding 30.0000 5 no
GO:0035639 purine ribonucleoside triphosphate binding 30.0000 4 no
GO:0043168 anion binding 30.0000 4 no
GO:0005540 hyaluronic acid binding 20.0000 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PGCB_HUMAN
GO:0048522 positive regulation of cellular process 90.0000 4 yes
GO:0042127 regulation of cell population proliferation 70.0000 4 yes
GO:0030334 regulation of cell migration 70.0000 5 no
GO:0048523 negative regulation of cellular process 70.0000 4 no
GO:0051128 regulation of cellular component organization 70.0000 4 no
GO:2000145 regulation of cell motility 70.0000 4 no
GO:0045595 regulation of cell differentiation 60.0000 4 yes
GO:0051240 positive regulation of multicellular organismal process 60.0000 4 yes
GO:2000026 regulation of multicellular organismal development 60.0000 4 yes
GO:0009893 positive regulation of metabolic process 60.0000 4 no
GO:0010604 positive regulation of macromolecule metabolic process 60.0000 5 no
GO:0010646 regulation of cell communication 60.0000 4 no
GO:0030030 cell projection organization 60.0000 4 no
GO:0031399 regulation of protein modification process 60.0000 6 no
GO:0031401 positive regulation of protein modification process 60.0000 7 no
GO:0051246 regulation of protein metabolic process 60.0000 5 no
GO:0051247 positive regulation of protein metabolic process 60.0000 6 no
GO:0060255 regulation of macromolecule metabolic process 60.0000 4 no
GO:0080090 regulation of primary metabolic process 60.0000 4 no
GO:0120036 plasma membrane bounded cell projection organization 60.0000 5 no
GO:0001932 regulation of protein phosphorylation 50.0000 7 no
GO:0001934 positive regulation of protein phosphorylation 50.0000 8 no
GO:0009892 negative regulation of metabolic process 50.0000 4 no
GO:0009966 regulation of signal transduction 50.0000 4 no
GO:0010562 positive regulation of phosphorus metabolic process 50.0000 6 no
GO:0010605 negative regulation of macromolecule metabolic process 50.0000 5 no
GO:0019220 regulation of phosphate metabolic process 50.0000 6 no
GO:0031323 regulation of cellular metabolic process 50.0000 4 no
GO:0031324 negative regulation of cellular metabolic process 50.0000 5 no
GO:0031325 positive regulation of cellular metabolic process 50.0000 5 no
GO:0031344 regulation of cell projection organization 50.0000 5 no
GO:0042325 regulation of phosphorylation 50.0000 7 no
GO:0042327 positive regulation of phosphorylation 50.0000 8 no
GO:0043549 regulation of kinase activity 50.0000 5 no
GO:0045859 regulation of protein kinase activity 50.0000 6 no
GO:0045937 positive regulation of phosphate metabolic process 50.0000 7 no
GO:0051174 regulation of phosphorus metabolic process 50.0000 5 no
GO:0051338 regulation of transferase activity 50.0000 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 50.0000 6 no
GO:1902531 regulation of intracellular signal transduction 50.0000 5 no
GO:0008284 positive regulation of cell population proliferation 40.0000 5 yes
GO:0045597 positive regulation of cell differentiation 40.0000 5 yes
GO:0050767 regulation of neurogenesis 40.0000 6 yes
GO:0051094 positive regulation of developmental process 40.0000 4 yes
GO:0051960 regulation of nervous system development 40.0000 5 yes
GO:0060284 regulation of cell development 40.0000 5 yes
GO:0001817 regulation of cytokine production 40.0000 4 no
GO:0009889 regulation of biosynthetic process 40.0000 4 no
GO:0010468 regulation of gene expression 40.0000 6 no
GO:0010556 regulation of macromolecule biosynthetic process 40.0000 5 no
GO:0010647 positive regulation of cell communication 40.0000 5 no
GO:0010648 negative regulation of cell communication 40.0000 5 no
GO:0010975 regulation of neuron projection development 40.0000 7 no
GO:0023056 positive regulation of signaling 40.0000 4 no
GO:0023057 negative regulation of signaling 40.0000 4 no
GO:0030155 regulation of cell adhesion 40.0000 4 no
GO:0030335 positive regulation of cell migration 40.0000 6 no
GO:0031175 neuron projection development 40.0000 6 no
GO:0031326 regulation of cellular biosynthetic process 40.0000 5 no
GO:0032101 regulation of response to external stimulus 40.0000 4 no
GO:0040017 positive regulation of locomotion 40.0000 4 no
GO:0042981 regulation of apoptotic process 40.0000 5 no
GO:0043067 regulation of programmed cell death 40.0000 4 no
GO:0043085 positive regulation of catalytic activity 40.0000 4 no
GO:0048585 negative regulation of response to stimulus 40.0000 4 no
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 40.0000 8 no
GO:0051049 regulation of transport 40.0000 4 no
GO:0051241 negative regulation of multicellular organismal process 40.0000 4 no
GO:0071310 cellular response to organic substance 40.0000 4 no
GO:0080134 regulation of response to stress 40.0000 4 no
GO:2000147 positive regulation of cell motility 40.0000 5 no
GO:0022607 cellular component assembly 40.0000 4 no
GO:0001501 skeletal system development 30.0000 4 yes
GO:0007417 central nervous system development 30.0000 4 yes
GO:0010720 positive regulation of cell development 30.0000 6 yes
GO:0034330 cell junction organization 30.0000 4 yes
GO:0050769 positive regulation of neurogenesis 30.0000 6 yes
GO:0050808 synapse organization 30.0000 5 yes
GO:0051962 positive regulation of nervous system development 30.0000 5 yes
GO:2000177 regulation of neural precursor cell proliferation 30.0000 5 yes
GO:2000179 positive regulation of neural precursor cell proliferation 30.0000 6 yes
GO:0001933 negative regulation of protein phosphorylation 30.0000 8 no
GO:0006468 protein phosphorylation 30.0000 5 no
GO:0006796 phosphate-containing compound metabolic process 30.0000 4 no
GO:0008285 negative regulation of cell population proliferation 30.0000 5 no
GO:0009967 positive regulation of signal transduction 30.0000 5 no
GO:0009968 negative regulation of signal transduction 30.0000 5 no
GO:0010243 response to organonitrogen compound 30.0000 4 no
GO:0010563 negative regulation of phosphorus metabolic process 30.0000 6 no
GO:0016310 phosphorylation 30.0000 5 no
GO:0022407 regulation of cell-cell adhesion 30.0000 5 no
GO:0031400 negative regulation of protein modification process 30.0000 7 no
GO:0032103 positive regulation of response to external stimulus 30.0000 5 no
GO:0034762 regulation of transmembrane transport 30.0000 4 no
GO:0036211 protein modification process 30.0000 4 no
GO:0042326 negative regulation of phosphorylation 30.0000 8 no
GO:0043408 regulation of MAPK cascade 30.0000 6 no
GO:0043412 macromolecule modification 30.0000 4 no
GO:0045596 negative regulation of cell differentiation 30.0000 5 no
GO:0045936 negative regulation of phosphate metabolic process 30.0000 7 no
GO:0048584 positive regulation of response to stimulus 30.0000 4 no
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 30.0000 9 no
GO:0051093 negative regulation of developmental process 30.0000 4 no
GO:0051130 positive regulation of cellular component organization 30.0000 5 no
GO:0051248 negative regulation of protein metabolic process 30.0000 6 no
GO:0080135 regulation of cellular response to stress 30.0000 4 no
GO:1901701 cellular response to oxygen-containing compound 30.0000 4 no
GO:1902533 positive regulation of intracellular signal transduction 30.0000 6 no
GO:0006355 regulation of DNA-templated transcription 30.0000 7 no
GO:0009890 negative regulation of biosynthetic process 30.0000 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 30.0000 6 no
GO:0010629 negative regulation of gene expression 30.0000 7 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 30.0000 5 no
GO:0031327 negative regulation of cellular biosynthetic process 30.0000 6 no
GO:0033674 positive regulation of kinase activity 30.0000 6 no
GO:0045860 positive regulation of protein kinase activity 30.0000 7 no
GO:0050804 modulation of chemical synaptic transmission 30.0000 5 no
GO:0050807 regulation of synapse organization 30.0000 5 no
GO:0050890 cognition 30.0000 4 no
GO:0051129 negative regulation of cellular component organization 30.0000 5 no
GO:0051252 regulation of RNA metabolic process 30.0000 5 no
GO:0051347 positive regulation of transferase activity 30.0000 5 no
GO:0051726 regulation of cell cycle 30.0000 4 no
GO:0055080 monoatomic cation homeostasis 30.0000 4 no
GO:0061097 regulation of protein tyrosine kinase activity 30.0000 7 no
GO:0099177 regulation of trans-synaptic signaling 30.0000 4 no
GO:2001141 regulation of RNA biosynthetic process 30.0000 6 no
GO:0022603 regulation of anatomical structure morphogenesis 30.0000 4 no
GO:0044057 regulation of system process 30.0000 4 no
GO:0048638 regulation of developmental growth 30.0000 4 no
GO:0002052 positive regulation of neuroblast proliferation 20.0000 7 yes
GO:0010001 glial cell differentiation 20.0000 4 yes
GO:1902692 regulation of neuroblast proliferation 20.0000 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TENR_HUMAN [view entry] [view interactions] Low throughput yes no
FBLN2_HUMAN [view interactions] Low throughput no yes
MMP1_HUMAN [view interactions] Low throughput no no
MMP2_HUMAN [view interactions] Low throughput no no
MMP3_HUMAN [view interactions] Low throughput no no
MMP7_HUMAN [view interactions] Low throughput no no
MMP8_HUMAN [view interactions] Low throughput no no
MMP10_HUMAN [view interactions] Low throughput no no
MMP13_HUMAN [view interactions] Low throughput no no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
LRRK2_HUMAN [view interactions] High throughput no yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
LYN_HUMAN [view entry] [view interactions] High throughput yes no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
PHS_HUMAN [view interactions] High throughput no yes
FBX11_HUMAN [view interactions] High throughput no no
CSPG2_HUMAN [view entry] [view interactions] High throughput yes no
ULK3_HUMAN [view interactions] High throughput no yes
REPI1_HUMAN [view interactions] High throughput no yes
CCYL1_HUMAN [view interactions] High throughput no yes
ZDBF2_HUMAN [view interactions] High throughput no yes
SET_HUMAN [view interactions] High throughput no yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
NACC2_HUMAN [view interactions] High throughput no yes
BGLR_HUMAN [view interactions] High throughput no yes
FGFR1_HUMAN [view entry] [view interactions] High throughput yes yes
CILP2_HUMAN [view interactions] High throughput no no
THSD4_HUMAN [view interactions] High throughput no no
METRL_HUMAN [view interactions] High throughput no no
BMP1_HUMAN [view interactions] High throughput no yes
CTRL_HUMAN [view interactions] High throughput no no
SEM3B_HUMAN [view interactions] High throughput no yes
LAMA5_HUMAN [view entry] [view interactions] High throughput yes no
ATS7_HUMAN [view interactions] High throughput no no
JAG2_HUMAN [view interactions] High throughput no yes
LAMB2_HUMAN [view interactions] High throughput no yes