Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CSPG2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CSPG2_HUMAN
GO:0005540 hyaluronic acid binding 33.3333 4 yes
GO:0043169 cation binding 33.3333 4 yes
GO:0046872 metal ion binding 33.3333 5 yes
GO:0008270 zinc ion binding 25.0000 7 no
GO:0046914 transition metal ion binding 25.0000 6 no
GO:0005509 calcium ion binding 16.6667 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in CSPG2_HUMAN
GO:0048522 positive regulation of cellular process 75.0000 4 yes
GO:0051128 regulation of cellular component organization 58.3333 4 no
GO:0045595 regulation of cell differentiation 50.0000 4 yes
GO:2000026 regulation of multicellular organismal development 50.0000 4 yes
GO:0051246 regulation of protein metabolic process 41.6667 5 no
GO:0051247 positive regulation of protein metabolic process 41.6667 6 no
GO:0060255 regulation of macromolecule metabolic process 41.6667 4 no
GO:0080090 regulation of primary metabolic process 41.6667 4 no
GO:0008284 positive regulation of cell population proliferation 41.6667 5 yes
GO:0010720 positive regulation of cell development 41.6667 6 yes
GO:0042127 regulation of cell population proliferation 41.6667 4 yes
GO:0045597 positive regulation of cell differentiation 41.6667 5 yes
GO:0050767 regulation of neurogenesis 41.6667 6 yes
GO:0050769 positive regulation of neurogenesis 41.6667 6 yes
GO:0051094 positive regulation of developmental process 41.6667 4 yes
GO:0051240 positive regulation of multicellular organismal process 41.6667 4 yes
GO:0051960 regulation of nervous system development 41.6667 5 yes
GO:0051962 positive regulation of nervous system development 41.6667 5 yes
GO:0060284 regulation of cell development 41.6667 5 yes
GO:0031344 regulation of cell projection organization 41.6667 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 41.6667 6 no
GO:0009966 regulation of signal transduction 41.6667 4 no
GO:0010646 regulation of cell communication 41.6667 4 no
GO:0010647 positive regulation of cell communication 41.6667 5 no
GO:0023056 positive regulation of signaling 41.6667 4 no
GO:0048523 negative regulation of cellular process 41.6667 4 no
GO:0048584 positive regulation of response to stimulus 41.6667 4 no
GO:0009893 positive regulation of metabolic process 41.6667 4 no
GO:0010604 positive regulation of macromolecule metabolic process 41.6667 5 no
GO:0019220 regulation of phosphate metabolic process 33.3333 6 no
GO:0030162 regulation of proteolysis 33.3333 6 no
GO:0031323 regulation of cellular metabolic process 33.3333 4 no
GO:0031325 positive regulation of cellular metabolic process 33.3333 5 no
GO:0031399 regulation of protein modification process 33.3333 6 no
GO:0031401 positive regulation of protein modification process 33.3333 7 no
GO:0042325 regulation of phosphorylation 33.3333 7 no
GO:0042327 positive regulation of phosphorylation 33.3333 8 no
GO:0043086 negative regulation of catalytic activity 33.3333 4 no
GO:0045937 positive regulation of phosphate metabolic process 33.3333 7 no
GO:0051174 regulation of phosphorus metabolic process 33.3333 5 no
GO:0051248 negative regulation of protein metabolic process 33.3333 6 no
GO:0001501 skeletal system development 33.3333 4 yes
GO:0002052 positive regulation of neuroblast proliferation 33.3333 7 yes
GO:1902692 regulation of neuroblast proliferation 33.3333 6 yes
GO:2000177 regulation of neural precursor cell proliferation 33.3333 5 yes
GO:2000179 positive regulation of neural precursor cell proliferation 33.3333 6 yes
GO:0010975 regulation of neuron projection development 33.3333 7 no
GO:0080134 regulation of response to stress 33.3333 4 no
GO:0006996 organelle organization 33.3333 4 no
GO:0009967 positive regulation of signal transduction 33.3333 5 no
GO:0022603 regulation of anatomical structure morphogenesis 33.3333 4 no
GO:0050807 regulation of synapse organization 33.3333 5 no
GO:0051130 positive regulation of cellular component organization 33.3333 5 no
GO:0001932 regulation of protein phosphorylation 33.3333 7 no
GO:0001934 positive regulation of protein phosphorylation 33.3333 8 no
GO:0009892 negative regulation of metabolic process 33.3333 4 no
GO:0010562 positive regulation of phosphorus metabolic process 33.3333 6 no
GO:0010605 negative regulation of macromolecule metabolic process 33.3333 5 no
GO:0010648 negative regulation of cell communication 25.0000 5 no
GO:0010951 negative regulation of endopeptidase activity 25.0000 7 no
GO:0023057 negative regulation of signaling 25.0000 4 no
GO:0042981 regulation of apoptotic process 25.0000 5 no
GO:0043066 negative regulation of apoptotic process 25.0000 6 no
GO:0043067 regulation of programmed cell death 25.0000 4 no
GO:0043069 negative regulation of programmed cell death 25.0000 5 no
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 25.0000 7 no
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 25.0000 8 no
GO:0045861 negative regulation of proteolysis 25.0000 7 no
GO:0048585 negative regulation of response to stimulus 25.0000 4 no
GO:0051336 regulation of hydrolase activity 25.0000 4 no
GO:0051346 negative regulation of hydrolase activity 25.0000 5 no
GO:0052547 regulation of peptidase activity 25.0000 5 no
GO:0052548 regulation of endopeptidase activity 25.0000 6 no
GO:2000116 regulation of cysteine-type endopeptidase activity 25.0000 7 no
GO:2000117 negative regulation of cysteine-type endopeptidase activity 25.0000 8 no
GO:0006508 proteolysis 25.0000 4 no
GO:0007417 central nervous system development 25.0000 4 yes
GO:0010001 glial cell differentiation 25.0000 4 yes
GO:0034330 cell junction organization 25.0000 4 no
GO:0050808 synapse organization 25.0000 5 no
GO:0007167 enzyme-linked receptor protein signaling pathway 25.0000 4 no
GO:0030030 cell projection organization 25.0000 4 no
GO:0032101 regulation of response to external stimulus 25.0000 4 no
GO:0043393 regulation of protein binding 25.0000 4 no
GO:0120036 plasma membrane bounded cell projection organization 25.0000 5 no
GO:0022607 cellular component assembly 25.0000 4 no
GO:0022898 regulation of transmembrane transporter activity 25.0000 4 no
GO:0033043 regulation of organelle organization 25.0000 5 no
GO:0034762 regulation of transmembrane transport 25.0000 4 no
GO:0034765 regulation of monoatomic ion transmembrane transport 25.0000 5 no
GO:0043269 regulation of monoatomic ion transport 25.0000 5 no
GO:0050804 modulation of chemical synaptic transmission 25.0000 5 no
GO:0051049 regulation of transport 25.0000 4 no
GO:0099175 regulation of postsynapse organization 25.0000 6 no
GO:0099177 regulation of trans-synaptic signaling 25.0000 4 no
GO:0009057 macromolecule catabolic process 25.0000 4 no
GO:0009968 negative regulation of signal transduction 25.0000 5 no
GO:0010466 negative regulation of peptidase activity 25.0000 6 no
GO:0008347 glial cell migration 16.6667 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
MMP9_HUMAN [view entry] [view interactions] Low throughput yes no
SRGN_HUMAN [view interactions] Low throughput no no
HPLN1_HUMAN [view entry] [view interactions] Low throughput yes yes
CD44_HUMAN [view entry] [view interactions] Low throughput yes yes
FBLN2_HUMAN [view interactions] Low throughput no yes
FBN1_HUMAN [view interactions] Low throughput no no
LYAM3_HUMAN [view interactions] Low throughput no no
LYAM1_HUMAN [view interactions] Low throughput no no
PLF4_HUMAN [view interactions] Low throughput no no
SDF1_HUMAN [view interactions] Low throughput no no
CCL2_HUMAN [view interactions] Low throughput no no
CCL8_HUMAN [view interactions] Low throughput no no
CCL20_HUMAN [view interactions] Low throughput no no
CCL5_HUMAN [view interactions] Low throughput no no
CCL21_HUMAN [view interactions] Low throughput no no
PTPRF_HUMAN [view entry] [view interactions] Low throughput yes yes
HSFX1_HUMAN [view interactions] High throughput no no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
ANS1B_HUMAN [view entry] [view interactions] High throughput yes yes
FA20C_HUMAN [view interactions] High throughput no no
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
RAB19_HUMAN [view interactions] High throughput no no
PGCB_HUMAN [view entry] [view interactions] High throughput yes yes
IFIX_HUMAN [view interactions] High throughput no no
TAFA4_HUMAN [view interactions] High throughput no no
SPDLY_HUMAN [view interactions] High throughput no yes
WDR76_HUMAN [view interactions] High throughput no no
RIGI_HUMAN [view interactions] High throughput no yes
LEG1_HUMAN [view interactions] High throughput no yes
MSMB_HUMAN [view interactions] High throughput no no
LEG7_HUMAN [view interactions] High throughput no no
IL17F_HUMAN [view interactions] High throughput no no
CCL3_HUMAN [view interactions] High throughput no no
TSG6_HUMAN [view interactions] High throughput no no
SLUR1_HUMAN [view interactions] High throughput no no
ST14_HUMAN [view entry] [view interactions] High throughput yes yes
SDF2L_HUMAN [view interactions] High throughput no yes
PRG2_HUMAN [view interactions] High throughput no no
LY86_HUMAN [view interactions] High throughput no no
NCTR3_HUMAN [view interactions] High throughput no no
GGH_HUMAN [view interactions] High throughput no yes
TDGF1_HUMAN [view interactions] High throughput no no
HEAT3_HUMAN [view interactions] High throughput no yes
RACK1_HUMAN [view interactions] High throughput no yes
SRP09_HUMAN [view interactions] High throughput no no
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no