Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SC6A6_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SC6A6_HUMAN
GO:0017076 purine nucleotide binding 73.3333 4 no
GO:0032555 purine ribonucleotide binding 73.3333 4 no
GO:0035639 purine ribonucleoside triphosphate binding 73.3333 4 no
GO:0016462 pyrophosphatase activity 66.6667 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 66.6667 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 66.6667 6 no
GO:0003924 GTPase activity 60.0000 7 no
GO:0005525 GTP binding 60.0000 5 no
GO:0019001 guanyl nucleotide binding 60.0000 5 no
GO:0032561 guanyl ribonucleotide binding 60.0000 5 no
GO:0019003 GDP binding 33.3333 4 no
GO:0019900 kinase binding 33.3333 4 no
GO:0019901 protein kinase binding 33.3333 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in SC6A6_HUMAN
GO:0048522 positive regulation of cellular process 80.0000 4 yes
GO:0006996 organelle organization 60.0000 4 no
GO:0051128 regulation of cellular component organization 53.3333 4 no
GO:0071702 organic substance transport 53.3333 4 yes
GO:0071705 nitrogen compound transport 53.3333 4 yes
GO:2000145 regulation of cell motility 46.6667 4 no
GO:0008284 positive regulation of cell population proliferation 46.6667 5 no
GO:0031323 regulation of cellular metabolic process 46.6667 4 no
GO:0042127 regulation of cell population proliferation 46.6667 4 no
GO:0048584 positive regulation of response to stimulus 46.6667 4 no
GO:0009893 positive regulation of metabolic process 46.6667 4 no
GO:0010604 positive regulation of macromolecule metabolic process 46.6667 5 no
GO:0060255 regulation of macromolecule metabolic process 46.6667 4 no
GO:0010646 regulation of cell communication 46.6667 4 yes
GO:0010941 regulation of cell death 46.6667 4 yes
GO:0007264 small GTPase mediated signal transduction 46.6667 4 no
GO:0007265 Ras protein signal transduction 46.6667 5 no
GO:0008104 protein localization 46.6667 4 no
GO:0030334 regulation of cell migration 46.6667 5 no
GO:0042981 regulation of apoptotic process 40.0000 6 no
GO:0043067 regulation of programmed cell death 40.0000 5 no
GO:0048523 negative regulation of cellular process 40.0000 4 no
GO:2000147 positive regulation of cell motility 40.0000 5 no
GO:0022607 cellular component assembly 40.0000 4 no
GO:0031344 regulation of cell projection organization 40.0000 5 no
GO:0051049 regulation of transport 40.0000 4 no
GO:0060627 regulation of vesicle-mediated transport 40.0000 4 no
GO:0061024 membrane organization 40.0000 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 40.0000 6 no
GO:0009966 regulation of signal transduction 40.0000 4 no
GO:0010468 regulation of gene expression 40.0000 5 no
GO:0031325 positive regulation of cellular metabolic process 40.0000 5 no
GO:0051171 regulation of nitrogen compound metabolic process 40.0000 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 40.0000 5 no
GO:0080090 regulation of primary metabolic process 40.0000 4 no
GO:0007010 cytoskeleton organization 40.0000 5 no
GO:0015031 protein transport 40.0000 4 no
GO:0016192 vesicle-mediated transport 40.0000 4 no
GO:0030335 positive regulation of cell migration 40.0000 6 no
GO:0040017 positive regulation of locomotion 40.0000 4 no
GO:0051493 regulation of cytoskeleton organization 33.3333 6 no
GO:0097435 supramolecular fiber organization 33.3333 4 no
GO:0002684 positive regulation of immune system process 33.3333 4 no
GO:0030030 cell projection organization 33.3333 4 no
GO:0030155 regulation of cell adhesion 33.3333 4 no
GO:0031175 neuron projection development 33.3333 6 no
GO:0031346 positive regulation of cell projection organization 33.3333 6 no
GO:0032880 regulation of protein localization 33.3333 5 no
GO:0044087 regulation of cellular component biogenesis 33.3333 4 no
GO:0051130 positive regulation of cellular component organization 33.3333 5 no
GO:0060341 regulation of cellular localization 33.3333 4 no
GO:0120036 plasma membrane bounded cell projection organization 33.3333 5 no
GO:0010647 positive regulation of cell communication 33.3333 5 no
GO:0023056 positive regulation of signaling 33.3333 4 no
GO:0045595 regulation of cell differentiation 33.3333 4 yes
GO:0051094 positive regulation of developmental process 33.3333 4 yes
GO:0006886 intracellular protein transport 33.3333 4 no
GO:0007015 actin filament organization 33.3333 5 no
GO:0022603 regulation of anatomical structure morphogenesis 33.3333 4 no
GO:0022604 regulation of cell morphogenesis 33.3333 5 no
GO:0032956 regulation of actin cytoskeleton organization 33.3333 5 no
GO:0032970 regulation of actin filament-based process 33.3333 4 no
GO:0033043 regulation of organelle organization 33.3333 5 no
GO:0002685 regulation of leukocyte migration 26.6667 4 no
GO:0002697 regulation of immune effector process 26.6667 4 no
GO:0002699 positive regulation of immune effector process 26.6667 5 no
GO:0002703 regulation of leukocyte mediated immunity 26.6667 5 no
GO:0006911 phagocytosis, engulfment 26.6667 7 no
GO:0010324 membrane invagination 26.6667 5 no
GO:0030031 cell projection assembly 26.6667 5 no
GO:0032101 regulation of response to external stimulus 26.6667 4 no
GO:0032103 positive regulation of response to external stimulus 26.6667 5 no
GO:0050776 regulation of immune response 26.6667 4 no
GO:0050920 regulation of chemotaxis 26.6667 4 no
GO:0060491 regulation of cell projection assembly 26.6667 5 no
GO:0099024 plasma membrane invagination 26.6667 6 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 26.6667 6 no
GO:1903829 positive regulation of protein localization 26.6667 5 no
GO:0043085 positive regulation of catalytic activity 26.6667 4 no
GO:0045785 positive regulation of cell adhesion 26.6667 5 no
GO:0071310 cellular response to organic substance 26.6667 4 no
GO:0009967 positive regulation of signal transduction 26.6667 5 no
GO:0010562 positive regulation of phosphorus metabolic process 26.6667 6 no
GO:0019220 regulation of phosphate metabolic process 26.6667 6 no
GO:0031399 regulation of protein modification process 26.6667 6 no
GO:0031401 positive regulation of protein modification process 26.6667 7 no
GO:0042325 regulation of phosphorylation 26.6667 7 no
GO:0042327 positive regulation of phosphorylation 26.6667 8 no
GO:0045937 positive regulation of phosphate metabolic process 26.6667 7 no
GO:0051174 regulation of phosphorus metabolic process 26.6667 5 no
GO:0051246 regulation of protein metabolic process 26.6667 5 no
GO:0051247 positive regulation of protein metabolic process 26.6667 6 no
GO:1902531 regulation of intracellular signal transduction 26.6667 5 no
GO:1902533 positive regulation of intracellular signal transduction 26.6667 6 no
GO:0010942 positive regulation of cell death 26.6667 5 yes
GO:0045597 positive regulation of cell differentiation 26.6667 5 yes
GO:0008360 regulation of cell shape 26.6667 6 no
GO:0030865 cortical cytoskeleton organization 26.6667 6 no
GO:0050804 modulation of chemical synaptic transmission 20.0000 5 yes
GO:0099177 regulation of trans-synaptic signaling 20.0000 4 yes
GO:0006811 ion transport 13.3333 4 yes
GO:0006812 cation transport 13.3333 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
GPR21_HUMAN [view interactions] High throughput no no
AGRG5_HUMAN [view interactions] High throughput no no
PDZ1P_HUMAN [view interactions] High throughput no no
NMUR2_HUMAN [view interactions] High throughput no yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
TMM17_HUMAN [view interactions] High throughput no yes
TM216_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
LEG9_HUMAN [view interactions] High throughput no yes
NHRF3_HUMAN [view interactions] High throughput no no
RN123_HUMAN [view interactions] High throughput no yes
DDX58_HUMAN [view interactions] High throughput no yes
FZR1_HUMAN [view interactions] High throughput no no
TR10C_HUMAN [view interactions] High throughput no no
OR6T1_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOD_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
B3GA1_HUMAN [view interactions] High throughput no yes
DIRA3_HUMAN [view interactions] High throughput no yes
CXD3_HUMAN [view interactions] High throughput no no
LAMP3_HUMAN [view interactions] High throughput no no
LYN_HUMAN [view entry] [view interactions] High throughput yes no
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
STX4_HUMAN [view entry] [view interactions] High throughput yes no
STX7_HUMAN [view entry] [view interactions] High throughput yes yes