Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SC6A6_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SC6A6_HUMAN
GO:0000166 nucleotide binding 64.7059 4 no
GO:0017076 purine nucleotide binding 64.7059 5 no
GO:0032555 purine ribonucleotide binding 64.7059 4 no
GO:0035639 purine ribonucleoside triphosphate binding 64.7059 4 no
GO:0043168 anion binding 64.7059 4 no
GO:0016462 pyrophosphatase activity 58.8235 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 58.8235 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 58.8235 6 no
GO:0003924 GTPase activity 52.9412 7 no
GO:0005525 GTP binding 52.9412 5 no
GO:0019001 guanyl nucleotide binding 52.9412 6 no
GO:0032561 guanyl ribonucleotide binding 52.9412 5 no
GO:0019003 GDP binding 29.4118 5 no
GO:0019900 kinase binding 23.5294 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in SC6A6_HUMAN
GO:0048522 positive regulation of cellular process 76.4706 4 yes
GO:0009893 positive regulation of metabolic process 47.0588 4 no
GO:0010604 positive regulation of macromolecule metabolic process 47.0588 5 no
GO:0048584 positive regulation of response to stimulus 47.0588 4 no
GO:0051128 regulation of cellular component organization 47.0588 4 no
GO:0060255 regulation of macromolecule metabolic process 47.0588 4 no
GO:0006996 organelle organization 47.0588 4 no
GO:0008104 protein localization 47.0588 4 no
GO:0010646 regulation of cell communication 47.0588 4 yes
GO:0071702 organic substance transport 47.0588 4 yes
GO:0071705 nitrogen compound transport 47.0588 4 yes
GO:0008284 positive regulation of cell population proliferation 41.1765 5 no
GO:0009966 regulation of signal transduction 41.1765 4 no
GO:0030334 regulation of cell migration 41.1765 5 no
GO:0030335 positive regulation of cell migration 41.1765 6 no
GO:0031323 regulation of cellular metabolic process 41.1765 4 no
GO:0040017 positive regulation of locomotion 41.1765 4 no
GO:0042127 regulation of cell population proliferation 41.1765 4 no
GO:0048523 negative regulation of cellular process 41.1765 4 no
GO:0080090 regulation of primary metabolic process 41.1765 4 no
GO:2000145 regulation of cell motility 41.1765 4 no
GO:2000147 positive regulation of cell motility 41.1765 5 no
GO:0007264 small GTPase-mediated signal transduction 41.1765 5 no
GO:0141124 intracellular signaling cassette 41.1765 4 no
GO:0010647 positive regulation of cell communication 35.2941 5 no
GO:0023056 positive regulation of signaling 35.2941 4 no
GO:0031325 positive regulation of cellular metabolic process 35.2941 5 no
GO:0031344 regulation of cell projection organization 35.2941 5 no
GO:0042981 regulation of apoptotic process 35.2941 5 no
GO:0043067 regulation of programmed cell death 35.2941 4 no
GO:0051049 regulation of transport 35.2941 4 no
GO:0060627 regulation of vesicle-mediated transport 35.2941 4 no
GO:0015031 protein transport 35.2941 4 no
GO:0022607 cellular component assembly 35.2941 4 no
GO:0002684 positive regulation of immune system process 29.4118 4 no
GO:0009889 regulation of biosynthetic process 29.4118 4 no
GO:0009967 positive regulation of signal transduction 29.4118 5 no
GO:0010468 regulation of gene expression 29.4118 6 no
GO:0010556 regulation of macromolecule biosynthetic process 29.4118 5 no
GO:0030030 cell projection organization 29.4118 4 no
GO:0030155 regulation of cell adhesion 29.4118 4 no
GO:0031326 regulation of cellular biosynthetic process 29.4118 5 no
GO:0031346 positive regulation of cell projection organization 29.4118 6 no
GO:0031399 regulation of protein modification process 29.4118 6 no
GO:0031401 positive regulation of protein modification process 29.4118 7 no
GO:0051130 positive regulation of cellular component organization 29.4118 5 no
GO:0051246 regulation of protein metabolic process 29.4118 5 no
GO:0051247 positive regulation of protein metabolic process 29.4118 6 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 29.4118 6 no
GO:1902531 regulation of intracellular signal transduction 29.4118 5 no
GO:0006886 intracellular protein transport 29.4118 4 no
GO:0032880 regulation of protein localization 29.4118 5 no
GO:0060341 regulation of cellular localization 29.4118 4 no
GO:0044087 regulation of cellular component biogenesis 29.4118 4 no
GO:0007015 actin filament organization 29.4118 5 no
GO:0097435 supramolecular fiber organization 29.4118 4 no
GO:0051094 positive regulation of developmental process 29.4118 4 yes
GO:0099177 regulation of trans-synaptic signaling 23.5294 4 yes
GO:0001932 regulation of protein phosphorylation 23.5294 7 no
GO:0001934 positive regulation of protein phosphorylation 23.5294 8 no
GO:0002697 regulation of immune effector process 23.5294 4 no
GO:0002703 regulation of leukocyte mediated immunity 23.5294 5 no
GO:0010562 positive regulation of phosphorus metabolic process 23.5294 6 no
GO:0019220 regulation of phosphate metabolic process 23.5294 6 no
GO:0031175 neuron projection development 23.5294 6 no
GO:0032101 regulation of response to external stimulus 23.5294 4 no
GO:0032103 positive regulation of response to external stimulus 23.5294 5 no
GO:0042325 regulation of phosphorylation 23.5294 7 no
GO:0042327 positive regulation of phosphorylation 23.5294 8 no
GO:0043085 positive regulation of catalytic activity 23.5294 4 no
GO:0045785 positive regulation of cell adhesion 23.5294 5 no
GO:0045937 positive regulation of phosphate metabolic process 23.5294 7 no
GO:0050920 regulation of chemotaxis 23.5294 4 no
GO:0051174 regulation of phosphorus metabolic process 23.5294 5 no
GO:0071310 cellular response to organic substance 23.5294 4 no
GO:0120036 plasma membrane bounded cell projection organization 23.5294 5 no
GO:1902533 positive regulation of intracellular signal transduction 23.5294 6 no
GO:0061024 membrane organization 23.5294 4 no
GO:1903829 positive regulation of protein localization 23.5294 5 no
GO:0022603 regulation of anatomical structure morphogenesis 23.5294 4 no
GO:0051129 negative regulation of cellular component organization 23.5294 5 no
GO:0007010 cytoskeleton organization 23.5294 5 no
GO:0060491 regulation of cell projection assembly 23.5294 5 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 23.5294 6 no
GO:0050804 modulation of chemical synaptic transmission 23.5294 5 yes
GO:0098657 import into cell 17.6471 4 yes
GO:0045595 regulation of cell differentiation 17.6471 4 yes
GO:0045597 positive regulation of cell differentiation 17.6471 5 yes
GO:0006836 neurotransmitter transport 11.7647 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
GPR21_HUMAN [view interactions] High throughput no no
AGRG5_HUMAN [view interactions] High throughput no no
PDZ1P_HUMAN [view interactions] High throughput no no
NMUR2_HUMAN [view interactions] High throughput no yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
TMM17_HUMAN [view interactions] High throughput no yes
TM216_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
CFTR_HUMAN [view interactions] High throughput no no
KCNK3_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
NHRF3_HUMAN [view interactions] High throughput no no
RN123_HUMAN [view interactions] High throughput no yes
RIGI_HUMAN [view interactions] High throughput no yes
FZR1_HUMAN [view interactions] High throughput no no
TR10C_HUMAN [view interactions] High throughput no no
OR6T1_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOD_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
UBP48_HUMAN [view interactions] High throughput no yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
B3GA1_HUMAN [view interactions] High throughput no yes
DIRA3_HUMAN [view interactions] High throughput no yes
CXD3_HUMAN [view interactions] High throughput no no
LAMP3_HUMAN [view interactions] High throughput no no
LYN_HUMAN [view entry] [view interactions] High throughput yes no
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
STX4_HUMAN [view entry] [view interactions] High throughput yes no
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
STING_HUMAN [view interactions] High throughput no yes
TGON2_HUMAN [view entry] [view interactions] High throughput yes yes
MUC18_HUMAN [view interactions] High throughput no yes