Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

DRS7B_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Putative oxidoreductase. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in DRS7B_HUMAN
GO:0043168 anion binding 37.5000 4 no
GO:0000166 nucleotide binding 33.3333 4 no
GO:0003924 GTPase activity 29.1667 7 no
GO:0005525 GTP binding 29.1667 5 no
GO:0016462 pyrophosphatase activity 29.1667 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 29.1667 4 no
GO:0017076 purine nucleotide binding 29.1667 5 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 29.1667 6 no
GO:0019001 guanyl nucleotide binding 29.1667 6 no
GO:0032555 purine ribonucleotide binding 29.1667 4 no
GO:0032561 guanyl ribonucleotide binding 29.1667 5 no
GO:0035639 purine ribonucleoside triphosphate binding 29.1667 4 no
GO:0043169 cation binding 25.0000 4 no
GO:0046872 metal ion binding 25.0000 5 no
GO:0019900 kinase binding 20.8333 4 no
GO:0019901 protein kinase binding 20.8333 5 no
GO:0140297 DNA-binding transcription factor binding 12.5000 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in DRS7B_HUMAN
GO:0060255 regulation of macromolecule metabolic process 75.0000 4 no
GO:0048522 positive regulation of cellular process 70.8333 4 no
GO:0009893 positive regulation of metabolic process 66.6667 4 no
GO:0010604 positive regulation of macromolecule metabolic process 66.6667 5 no
GO:0080090 regulation of primary metabolic process 66.6667 4 no
GO:0031323 regulation of cellular metabolic process 62.5000 4 no
GO:0048523 negative regulation of cellular process 58.3333 4 no
GO:0010646 regulation of cell communication 54.1667 4 no
GO:0051128 regulation of cellular component organization 54.1667 4 no
GO:0051246 regulation of protein metabolic process 54.1667 5 no
GO:0009889 regulation of biosynthetic process 50.0000 4 no
GO:0010468 regulation of gene expression 50.0000 6 no
GO:0010556 regulation of macromolecule biosynthetic process 50.0000 5 no
GO:0022607 cellular component assembly 50.0000 4 no
GO:0031326 regulation of cellular biosynthetic process 50.0000 5 no
GO:0051247 positive regulation of protein metabolic process 50.0000 6 no
GO:0009966 regulation of signal transduction 45.8333 4 no
GO:0031325 positive regulation of cellular metabolic process 45.8333 5 no
GO:0048584 positive regulation of response to stimulus 45.8333 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 45.8333 5 no
GO:0006996 organelle organization 41.6667 4 no
GO:0010647 positive regulation of cell communication 41.6667 5 no
GO:0023056 positive regulation of signaling 41.6667 4 no
GO:0031399 regulation of protein modification process 41.6667 6 no
GO:0033043 regulation of organelle organization 41.6667 5 no
GO:0044087 regulation of cellular component biogenesis 41.6667 4 no
GO:0042127 regulation of cell population proliferation 41.6667 4 no
GO:0001932 regulation of protein phosphorylation 37.5000 7 no
GO:0009892 negative regulation of metabolic process 37.5000 4 no
GO:0009967 positive regulation of signal transduction 37.5000 5 no
GO:0019220 regulation of phosphate metabolic process 37.5000 6 no
GO:0030334 regulation of cell migration 37.5000 5 no
GO:0030335 positive regulation of cell migration 37.5000 6 no
GO:0031401 positive regulation of protein modification process 37.5000 7 no
GO:0040017 positive regulation of locomotion 37.5000 4 no
GO:0042325 regulation of phosphorylation 37.5000 7 no
GO:0051049 regulation of transport 37.5000 4 no
GO:0051130 positive regulation of cellular component organization 37.5000 5 no
GO:0051174 regulation of phosphorus metabolic process 37.5000 5 no
GO:1902531 regulation of intracellular signal transduction 37.5000 5 no
GO:1902533 positive regulation of intracellular signal transduction 37.5000 6 no
GO:2000145 regulation of cell motility 37.5000 4 no
GO:2000147 positive regulation of cell motility 37.5000 5 no
GO:0008104 protein localization 37.5000 4 no
GO:0042981 regulation of apoptotic process 37.5000 5 no
GO:0043067 regulation of programmed cell death 37.5000 4 no
GO:0051252 regulation of RNA metabolic process 37.5000 5 no
GO:0051726 regulation of cell cycle 37.5000 4 no
GO:0009890 negative regulation of biosynthetic process 33.3333 5 no
GO:0010605 negative regulation of macromolecule metabolic process 33.3333 5 no
GO:0031324 negative regulation of cellular metabolic process 33.3333 5 no
GO:0043523 regulation of neuron apoptotic process 33.3333 6 no
GO:0051240 positive regulation of multicellular organismal process 33.3333 4 no
GO:0071310 cellular response to organic substance 33.3333 4 no
GO:0098657 import into cell 33.3333 4 no
GO:0006355 regulation of DNA-templated transcription 33.3333 7 no
GO:0006357 regulation of transcription by RNA polymerase II 33.3333 8 no
GO:0009891 positive regulation of biosynthetic process 33.3333 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 33.3333 6 no
GO:0010628 positive regulation of gene expression 33.3333 7 no
GO:0031328 positive regulation of cellular biosynthetic process 33.3333 6 no
GO:2001141 regulation of RNA biosynthetic process 33.3333 6 no
GO:0010648 negative regulation of cell communication 33.3333 5 no
GO:0023057 negative regulation of signaling 33.3333 4 no
GO:0048585 negative regulation of response to stimulus 33.3333 4 no
GO:0001934 positive regulation of protein phosphorylation 29.1667 8 no
GO:0002684 positive regulation of immune system process 29.1667 4 no
GO:0010558 negative regulation of macromolecule biosynthetic process 29.1667 6 no
GO:0010562 positive regulation of phosphorus metabolic process 29.1667 6 no
GO:0031327 negative regulation of cellular biosynthetic process 29.1667 6 no
GO:0031344 regulation of cell projection organization 29.1667 5 no
GO:0042327 positive regulation of phosphorylation 29.1667 8 no
GO:0044089 positive regulation of cellular component biogenesis 29.1667 5 no
GO:0045937 positive regulation of phosphate metabolic process 29.1667 7 no
GO:0097435 supramolecular fiber organization 29.1667 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 29.1667 6 no
GO:0008284 positive regulation of cell population proliferation 29.1667 5 no
GO:0032880 regulation of protein localization 29.1667 5 no
GO:0060341 regulation of cellular localization 29.1667 4 no
GO:0071702 organic substance transport 29.1667 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 29.1667 5 no
GO:0009968 negative regulation of signal transduction 29.1667 5 no
GO:0009894 regulation of catabolic process 29.1667 4 no
GO:0010564 regulation of cell cycle process 29.1667 5 no
GO:0001817 regulation of cytokine production 25.0000 4 no
GO:0010629 negative regulation of gene expression 25.0000 7 no
GO:0010638 positive regulation of organelle organization 25.0000 6 no
GO:0030030 cell projection organization 25.0000 4 no
GO:0032956 regulation of actin cytoskeleton organization 25.0000 5 no
GO:0032970 regulation of actin filament-based process 25.0000 4 no
GO:0043933 protein-containing complex organization 25.0000 4 no
GO:0051493 regulation of cytoskeleton organization 25.0000 6 no
GO:0060627 regulation of vesicle-mediated transport 25.0000 4 no
GO:1902903 regulation of supramolecular fiber organization 25.0000 5 no
GO:0070201 regulation of establishment of protein localization 25.0000 6 no
GO:1903829 positive regulation of protein localization 25.0000 5 no
GO:0006915 apoptotic process 25.0000 4 no
GO:0010243 response to organonitrogen compound 25.0000 4 no
GO:0043066 negative regulation of apoptotic process 25.0000 6 no
GO:0043069 negative regulation of programmed cell death 25.0000 5 no
GO:0071705 nitrogen compound transport 25.0000 4 no
GO:1901701 cellular response to oxygen-containing compound 25.0000 4 no
GO:0043408 regulation of MAPK cascade 25.0000 6 no
GO:0045893 positive regulation of DNA-templated transcription 25.0000 8 no
GO:0051254 positive regulation of RNA metabolic process 25.0000 6 no
GO:0080134 regulation of response to stress 25.0000 4 no
GO:1902680 positive regulation of RNA biosynthetic process 25.0000 7 no
GO:0036211 protein modification process 25.0000 4 no
GO:0043412 macromolecule modification 25.0000 4 no
GO:0045787 positive regulation of cell cycle 25.0000 5 no
GO:0007015 actin filament organization 20.8333 5 no
GO:0007264 small GTPase-mediated signal transduction 20.8333 5 no
GO:0010810 regulation of cell-substrate adhesion 20.8333 5 no
GO:0030155 regulation of cell adhesion 20.8333 4 no
GO:0031346 positive regulation of cell projection organization 20.8333 6 no
GO:0032101 regulation of response to external stimulus 20.8333 4 no
GO:0032103 positive regulation of response to external stimulus 20.8333 5 no
GO:0032231 regulation of actin filament bundle assembly 20.8333 5 no
GO:0051129 negative regulation of cellular component organization 20.8333 5 no
GO:0051241 negative regulation of multicellular organismal process 20.8333 4 no
GO:0060491 regulation of cell projection assembly 20.8333 5 no
GO:0065003 protein-containing complex assembly 20.8333 5 no
GO:0110053 regulation of actin filament organization 20.8333 6 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 20.8333 6 no
GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 20.8333 6 no
GO:0141124 intracellular signaling cassette 20.8333 4 no
GO:1902905 positive regulation of supramolecular fiber organization 20.8333 6 no
GO:0051046 regulation of secretion 20.8333 5 no
GO:1903530 regulation of secretion by cell 20.8333 4 no
GO:0014070 response to organic cyclic compound 20.8333 4 no
GO:0043524 negative regulation of neuron apoptotic process 20.8333 7 no
GO:0050804 modulation of chemical synaptic transmission 20.8333 5 no
GO:0051402 neuron apoptotic process 20.8333 5 no
GO:0099177 regulation of trans-synaptic signaling 20.8333 4 no
GO:1901699 cellular response to nitrogen compound 20.8333 4 no
GO:0043085 positive regulation of catalytic activity 20.8333 4 no
GO:0043410 positive regulation of MAPK cascade 20.8333 7 no
GO:0043549 regulation of kinase activity 20.8333 5 no
GO:0045944 positive regulation of transcription by RNA polymerase II 20.8333 9 no
GO:0051336 regulation of hydrolase activity 20.8333 4 no
GO:0051338 regulation of transferase activity 20.8333 4 no
GO:0051345 positive regulation of hydrolase activity 20.8333 5 no
GO:0033365 protein localization to organelle 20.8333 5 no
GO:0032446 protein modification by small protein conjugation 20.8333 7 no
GO:0043687 post-translational protein modification 20.8333 5 no
GO:0070647 protein modification by small protein conjugation or removal 20.8333 6 no
GO:0090068 positive regulation of cell cycle process 20.8333 6 no
GO:1901987 regulation of cell cycle phase transition 20.8333 6 no
GO:0051050 positive regulation of transport 20.8333 4 no
GO:0006954 inflammatory response 12.5000 4 yes
GO:0002521 leukocyte differentiation 8.3333 4 yes
GO:0002573 myeloid leukocyte differentiation 8.3333 5 yes
GO:0006796 phosphate-containing compound metabolic process 8.3333 4 yes
GO:0030099 myeloid cell differentiation 8.3333 4 yes
GO:0060612 adipose tissue development 8.3333 5 yes
GO:0061448 connective tissue development 8.3333 4 yes
GO:1901566 organonitrogen compound biosynthetic process 8.3333 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
BABA2_HUMAN [view interactions] High throughput no yes
RIPK4_HUMAN [view interactions] High throughput no no
GOT1B_HUMAN [view interactions] High throughput no yes
GLPB_HUMAN [view interactions] High throughput no no
NMES1_HUMAN [view interactions] High throughput no no
COQ9_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
RHG31_HUMAN [view interactions] High throughput no yes
RASH_HUMAN [view entry] [view interactions] High throughput yes no
PGFRB_HUMAN [view interactions] High throughput no yes
VGFR2_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
HSC20_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
MED19_HUMAN [view interactions] High throughput no yes
NFKB1_HUMAN [view interactions] High throughput no yes
TECT3_HUMAN [view interactions] High throughput no yes
TECT2_HUMAN [view interactions] High throughput no yes
KCNK3_HUMAN [view interactions] High throughput no no
TP53B_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
HECW2_HUMAN [view entry] [view interactions] High throughput yes no
EGFR_HUMAN [view interactions] High throughput no no
EED_HUMAN [view interactions] High throughput no yes
WDTC1_HUMAN [view interactions] High throughput no yes
WWP2_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
HNRPL_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
RECQ4_HUMAN [view interactions] High throughput no yes
GLP1R_HUMAN [view interactions] High throughput no no
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
BRD7_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
BRD1_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
INS_HUMAN [view interactions] High throughput no no
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
PD1L1_HUMAN [view interactions] High throughput no no
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
T184A_HUMAN [view interactions] High throughput no no
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
VIPR1_HUMAN [view interactions] High throughput no yes
DMB_HUMAN [view interactions] High throughput no no
TMM72_HUMAN [view interactions] High throughput no no
S22A9_HUMAN [view interactions] High throughput no no
KLK5_HUMAN [view interactions] High throughput no no
FFAR1_HUMAN [view interactions] High throughput no no
DPEP1_HUMAN [view interactions] High throughput no no
AT2A3_HUMAN [view interactions] High throughput no yes
KCNK1_HUMAN [view entry] [view interactions] High throughput yes yes
EAA3_HUMAN [view entry] [view interactions] High throughput yes yes
VSIG4_HUMAN [view interactions] High throughput no no
NAAA_HUMAN [view interactions] High throughput no yes
TSP50_HUMAN [view interactions] High throughput no no
AQP3_HUMAN [view interactions] High throughput no no
THTPA_HUMAN [view interactions] High throughput no yes
A4GCT_HUMAN [view interactions] High throughput no no
LAMP3_HUMAN [view interactions] High throughput no no
HUMMR_HUMAN [view interactions] High throughput no yes
ITLN1_HUMAN [view interactions] High throughput no no
KLRD1_HUMAN [view interactions] High throughput no no
GPR45_HUMAN [view interactions] High throughput no no
RAMP3_HUMAN [view interactions] High throughput no no
PPBI_HUMAN [view interactions] High throughput no no
GPIX_HUMAN [view interactions] High throughput no no
CD70_HUMAN [view interactions] High throughput no no
MFD4A_HUMAN [view interactions] High throughput no yes
LRC25_HUMAN [view interactions] High throughput no yes
KLRB1_HUMAN [view interactions] High throughput no yes
GP182_HUMAN [view interactions] High throughput no no
SPRTN_HUMAN [view interactions] High throughput no yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
BASI_HUMAN [view entry] [view interactions] High throughput yes no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOD_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
COMD2_HUMAN [view interactions] High throughput no yes
FOXA1_HUMAN [view interactions] High throughput no no
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
BRCA1_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
CL16A_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
OTUD1_HUMAN [view interactions] High throughput no yes
UBE2H_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
ACINU_HUMAN [view interactions] High throughput no yes
RAB1B_HUMAN [view entry] [view interactions] High throughput yes yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
TRI14_HUMAN [view interactions] High throughput no yes
CLPP_HUMAN [view interactions] High throughput no yes
STING_HUMAN [view interactions] High throughput no yes
ESYT2_HUMAN [view entry] [view interactions] High throughput yes yes
RFA1_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes