Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

DRS7B_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Putative oxidoreductase. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in DRS7B_HUMAN
GO:0003924 GTPase activity 35.0000 7 no
GO:0005525 GTP binding 35.0000 5 no
GO:0016462 pyrophosphatase activity 35.0000 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 35.0000 4 no
GO:0017076 purine nucleotide binding 35.0000 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 35.0000 6 no
GO:0019001 guanyl nucleotide binding 35.0000 5 no
GO:0032555 purine ribonucleotide binding 35.0000 4 no
GO:0032561 guanyl ribonucleotide binding 35.0000 5 no
GO:0035639 purine ribonucleoside triphosphate binding 35.0000 4 no
GO:0019900 kinase binding 25.0000 4 no
GO:0019901 protein kinase binding 25.0000 5 no
GO:0140297 DNA-binding transcription factor binding 15.0000 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in DRS7B_HUMAN
GO:0060255 regulation of macromolecule metabolic process 85.0000 4 no
GO:0009893 positive regulation of metabolic process 80.0000 4 no
GO:0010604 positive regulation of macromolecule metabolic process 80.0000 5 no
GO:0048522 positive regulation of cellular process 80.0000 4 no
GO:0051171 regulation of nitrogen compound metabolic process 75.0000 4 no
GO:0080090 regulation of primary metabolic process 75.0000 4 no
GO:0031323 regulation of cellular metabolic process 70.0000 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 70.0000 5 no
GO:0048523 negative regulation of cellular process 65.0000 4 no
GO:0051049 regulation of transport 60.0000 4 no
GO:0051246 regulation of protein metabolic process 60.0000 5 no
GO:0051247 positive regulation of protein metabolic process 60.0000 6 no
GO:0010646 regulation of cell communication 55.0000 4 no
GO:0031325 positive regulation of cellular metabolic process 55.0000 5 no
GO:0051128 regulation of cellular component organization 55.0000 4 no
GO:0006996 organelle organization 50.0000 4 no
GO:0010468 regulation of gene expression 50.0000 5 no
GO:0022607 cellular component assembly 50.0000 4 no
GO:0033043 regulation of organelle organization 50.0000 5 no
GO:0010562 positive regulation of phosphorus metabolic process 45.0000 6 no
GO:0010941 regulation of cell death 45.0000 4 no
GO:0019220 regulation of phosphate metabolic process 45.0000 6 no
GO:0042325 regulation of phosphorylation 45.0000 7 no
GO:0042327 positive regulation of phosphorylation 45.0000 8 no
GO:0042981 regulation of apoptotic process 45.0000 6 no
GO:0043067 regulation of programmed cell death 45.0000 5 no
GO:0045937 positive regulation of phosphate metabolic process 45.0000 7 no
GO:0051174 regulation of phosphorus metabolic process 45.0000 5 no
GO:0009966 regulation of signal transduction 45.0000 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 45.0000 5 no
GO:0042127 regulation of cell population proliferation 45.0000 4 no
GO:0048584 positive regulation of response to stimulus 45.0000 4 no
GO:0044087 regulation of cellular component biogenesis 45.0000 4 no
GO:0051726 regulation of cell cycle 40.0000 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 40.0000 6 no
GO:2000145 regulation of cell motility 40.0000 4 no
GO:2000147 positive regulation of cell motility 40.0000 5 no
GO:0001932 regulation of protein phosphorylation 40.0000 7 no
GO:0001934 positive regulation of protein phosphorylation 40.0000 8 no
GO:0008104 protein localization 40.0000 4 no
GO:0010647 positive regulation of cell communication 40.0000 5 no
GO:0023056 positive regulation of signaling 40.0000 4 no
GO:0031399 regulation of protein modification process 40.0000 6 no
GO:0031401 positive regulation of protein modification process 40.0000 7 no
GO:0043085 positive regulation of catalytic activity 40.0000 4 no
GO:0051240 positive regulation of multicellular organismal process 40.0000 4 no
GO:0071310 cellular response to organic substance 40.0000 4 no
GO:0010628 positive regulation of gene expression 40.0000 6 no
GO:0030334 regulation of cell migration 40.0000 5 no
GO:0030335 positive regulation of cell migration 40.0000 6 no
GO:0031344 regulation of cell projection organization 40.0000 5 no
GO:0040017 positive regulation of locomotion 40.0000 4 no
GO:0051130 positive regulation of cellular component organization 35.0000 5 no
GO:0051050 positive regulation of transport 35.0000 4 no
GO:0032880 regulation of protein localization 35.0000 5 no
GO:0036211 protein modification process 35.0000 4 no
GO:0043412 macromolecule modification 35.0000 4 no
GO:0043523 regulation of neuron apoptotic process 35.0000 6 no
GO:0051336 regulation of hydrolase activity 35.0000 4 no
GO:0051345 positive regulation of hydrolase activity 35.0000 5 no
GO:0060341 regulation of cellular localization 35.0000 4 no
GO:1901214 regulation of neuron death 35.0000 5 no
GO:0002684 positive regulation of immune system process 35.0000 4 no
GO:0009889 regulation of biosynthetic process 35.0000 4 no
GO:0009892 negative regulation of metabolic process 35.0000 4 no
GO:0009967 positive regulation of signal transduction 35.0000 5 no
GO:0010648 negative regulation of cell communication 35.0000 5 no
GO:0023057 negative regulation of signaling 35.0000 4 no
GO:0031326 regulation of cellular biosynthetic process 35.0000 5 no
GO:0048585 negative regulation of response to stimulus 35.0000 4 no
GO:0051252 regulation of RNA metabolic process 35.0000 5 no
GO:1902531 regulation of intracellular signal transduction 35.0000 5 no
GO:1902533 positive regulation of intracellular signal transduction 35.0000 6 no
GO:0030030 cell projection organization 35.0000 4 no
GO:0044089 positive regulation of cellular component biogenesis 35.0000 5 no
GO:0051094 positive regulation of developmental process 30.0000 4 no
GO:0051129 negative regulation of cellular component organization 30.0000 5 no
GO:0051493 regulation of cytoskeleton organization 30.0000 6 no
GO:0031175 neuron projection development 30.0000 6 no
GO:0060627 regulation of vesicle-mediated transport 30.0000 4 no
GO:0120036 plasma membrane bounded cell projection organization 30.0000 5 no
GO:1903829 positive regulation of protein localization 30.0000 5 no
GO:0010243 response to organonitrogen compound 30.0000 4 no
GO:0014070 response to organic cyclic compound 30.0000 4 no
GO:0016192 vesicle-mediated transport 30.0000 4 no
GO:0033674 positive regulation of kinase activity 30.0000 6 no
GO:0043549 regulation of kinase activity 30.0000 5 no
GO:0051223 regulation of protein transport 30.0000 5 no
GO:0051338 regulation of transferase activity 30.0000 4 no
GO:0051347 positive regulation of transferase activity 30.0000 5 no
GO:0060548 negative regulation of cell death 30.0000 5 no
GO:0070201 regulation of establishment of protein localization 30.0000 6 no
GO:0006355 regulation of DNA-templated transcription 30.0000 6 no
GO:0006357 regulation of transcription by RNA polymerase II 30.0000 7 no
GO:0008284 positive regulation of cell population proliferation 30.0000 5 no
GO:0009891 positive regulation of biosynthetic process 30.0000 5 no
GO:0009894 regulation of catabolic process 30.0000 4 no
GO:0009968 negative regulation of signal transduction 30.0000 5 no
GO:0010556 regulation of macromolecule biosynthetic process 30.0000 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 30.0000 6 no
GO:0010605 negative regulation of macromolecule metabolic process 30.0000 5 no
GO:0031328 positive regulation of cellular biosynthetic process 30.0000 6 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 30.0000 6 no
GO:1903506 regulation of nucleic acid-templated transcription 30.0000 7 no
GO:2001141 regulation of RNA biosynthetic process 30.0000 6 no
GO:0010564 regulation of cell cycle process 30.0000 5 no
GO:0022603 regulation of anatomical structure morphogenesis 30.0000 4 no
GO:0032956 regulation of actin cytoskeleton organization 30.0000 5 no
GO:0032970 regulation of actin filament-based process 30.0000 4 no
GO:0045595 regulation of cell differentiation 30.0000 4 no
GO:0051241 negative regulation of multicellular organismal process 25.0000 4 no
GO:0051495 positive regulation of cytoskeleton organization 25.0000 7 no
GO:0061024 membrane organization 25.0000 4 no
GO:0097435 supramolecular fiber organization 25.0000 4 no
GO:1902903 regulation of supramolecular fiber organization 25.0000 5 no
GO:1902905 positive regulation of supramolecular fiber organization 25.0000 6 no
GO:0031346 positive regulation of cell projection organization 25.0000 6 no
GO:0051222 positive regulation of protein transport 25.0000 5 no
GO:0060491 regulation of cell projection assembly 25.0000 5 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 25.0000 6 no
GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 25.0000 6 no
GO:1904951 positive regulation of establishment of protein localization 25.0000 6 no
GO:0080134 regulation of response to stress 25.0000 4 no
GO:0080135 regulation of cellular response to stress 25.0000 4 no
GO:0006796 phosphate-containing compound metabolic process 25.0000 4 yes
GO:0010952 positive regulation of peptidase activity 25.0000 6 no
GO:0030162 regulation of proteolysis 25.0000 6 no
GO:0043066 negative regulation of apoptotic process 25.0000 7 no
GO:0043069 negative regulation of programmed cell death 25.0000 6 no
GO:0045859 regulation of protein kinase activity 25.0000 6 no
GO:0045860 positive regulation of protein kinase activity 25.0000 7 no
GO:0045862 positive regulation of proteolysis 25.0000 7 no
GO:0052547 regulation of peptidase activity 25.0000 5 no
GO:0071702 organic substance transport 25.0000 4 no
GO:0071705 nitrogen compound transport 25.0000 4 no
GO:1901215 negative regulation of neuron death 25.0000 6 no
GO:1901701 cellular response to oxygen-containing compound 25.0000 4 no
GO:0001817 regulation of cytokine production 25.0000 4 no
GO:0008285 negative regulation of cell population proliferation 25.0000 5 no
GO:0010942 positive regulation of cell death 25.0000 5 no
GO:0031324 negative regulation of cellular metabolic process 25.0000 5 no
GO:0042176 regulation of protein catabolic process 25.0000 5 no
GO:0043408 regulation of MAPK cascade 25.0000 6 no
GO:0043410 positive regulation of MAPK cascade 25.0000 7 no
GO:0045893 positive regulation of DNA-templated transcription 25.0000 7 no
GO:0050776 regulation of immune response 25.0000 4 no
GO:0051254 positive regulation of RNA metabolic process 25.0000 6 no
GO:1902680 positive regulation of RNA biosynthetic process 25.0000 7 no
GO:1903508 positive regulation of nucleic acid-templated transcription 25.0000 8 no
GO:0007010 cytoskeleton organization 25.0000 5 no
GO:0007264 small GTPase mediated signal transduction 25.0000 4 no
GO:0007265 Ras protein signal transduction 25.0000 5 no
GO:0010638 positive regulation of organelle organization 25.0000 6 no
GO:0010810 regulation of cell-substrate adhesion 25.0000 5 no
GO:0022604 regulation of cell morphogenesis 25.0000 5 no
GO:0030155 regulation of cell adhesion 25.0000 4 no
GO:0045597 positive regulation of cell differentiation 25.0000 5 no
GO:0045787 positive regulation of cell cycle 25.0000 5 no
GO:0043393 regulation of protein binding 20.0000 4 yes
GO:0002521 leukocyte differentiation 10.0000 4 yes
GO:0002573 myeloid leukocyte differentiation 10.0000 5 yes
GO:0006954 inflammatory response 10.0000 4 yes
GO:0030099 myeloid cell differentiation 10.0000 4 yes
GO:1901566 organonitrogen compound biosynthetic process 10.0000 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in DRS7B_HUMAN
DOID:10595 Charcot-Marie-Tooth disease 10.0000 6 no
DOID:440 neuromuscular disease 10.0000 5 no
DOID:574 peripheral nervous system disease 10.0000 3 no
DOID:870 neuropathy 10.0000 4 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
BABA2_HUMAN [view interactions] High throughput no yes
RIPK4_HUMAN [view interactions] High throughput no no
GOT1B_HUMAN [view interactions] High throughput no yes
GLPB_HUMAN [view interactions] High throughput no no
NMES1_HUMAN [view interactions] High throughput no no
COQ9_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
RHG31_HUMAN [view interactions] High throughput no yes
RASH_HUMAN [view entry] [view interactions] High throughput yes no
PGFRB_HUMAN [view interactions] High throughput no yes
VGFR2_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
HSC20_HUMAN [view interactions] High throughput no yes
MED19_HUMAN [view interactions] High throughput no yes
NFKB1_HUMAN [view interactions] High throughput no yes
TECT3_HUMAN [view interactions] High throughput no yes
TECT2_HUMAN [view interactions] High throughput no yes
TP53B_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
HECW2_HUMAN [view entry] [view interactions] High throughput yes no
EGFR_HUMAN [view interactions] High throughput no no
EED_HUMAN [view interactions] High throughput no yes
WDTC1_HUMAN [view interactions] High throughput no yes
WWP2_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
HNRPL_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
RECQ4_HUMAN [view interactions] High throughput no yes
GLP1R_HUMAN [view interactions] High throughput no no
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
BRD7_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
BRD1_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
INS_HUMAN [view interactions] High throughput no no
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
PD1L1_HUMAN [view interactions] High throughput no no
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
T184A_HUMAN [view interactions] High throughput no no
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
VIPR1_HUMAN [view interactions] High throughput no yes
DMB_HUMAN [view interactions] High throughput no no
TMM72_HUMAN [view interactions] High throughput no no
S22A9_HUMAN [view interactions] High throughput no no
KLK5_HUMAN [view interactions] High throughput no no
FFAR1_HUMAN [view interactions] High throughput no no
DPEP1_HUMAN [view interactions] High throughput no no
AT2A3_HUMAN [view interactions] High throughput no yes
KCNK1_HUMAN [view interactions] High throughput no yes
EAA3_HUMAN [view entry] [view interactions] High throughput yes yes
VSIG4_HUMAN [view interactions] High throughput no no
NAAA_HUMAN [view interactions] High throughput no yes
TSP50_HUMAN [view interactions] High throughput no no
AQP3_HUMAN [view interactions] High throughput no no
THTPA_HUMAN [view interactions] High throughput no yes
A4GCT_HUMAN [view interactions] High throughput no no
LAMP3_HUMAN [view interactions] High throughput no no
HUMMR_HUMAN [view interactions] High throughput no yes
ITLN1_HUMAN [view interactions] High throughput no no
KLRD1_HUMAN [view interactions] High throughput no no
GPR45_HUMAN [view interactions] High throughput no no
RAMP3_HUMAN [view interactions] High throughput no no
PPBI_HUMAN [view interactions] High throughput no no
GPIX_HUMAN [view interactions] High throughput no no
CD70_HUMAN [view interactions] High throughput no no
MFD4A_HUMAN [view interactions] High throughput no yes
LRC25_HUMAN [view interactions] High throughput no yes
KLRB1_HUMAN [view interactions] High throughput no yes
GP182_HUMAN [view interactions] High throughput no no
SPRTN_HUMAN [view interactions] High throughput no yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
BASI_HUMAN [view entry] [view interactions] High throughput yes no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOD_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
COMD2_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
ACINU_HUMAN [view interactions] High throughput no yes
RAB1B_HUMAN [view entry] [view interactions] High throughput yes yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
TRI14_HUMAN [view interactions] High throughput no yes
NATD1_HUMAN [view interactions] Computational no no