Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PRR12_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

[View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

Position Amino acid Mutation Disease Overlap with binding region
1169 Arg Trp Neuroocularsyndrome(NOC) -
1970 Leu Pro Neuroocularsyndrome(NOC) -

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PRR12_HUMAN
GO:0003677 DNA binding 33.3333 4 no
GO:0003723 RNA binding 22.2222 4 no
GO:0019900 kinase binding 22.2222 4 no
GO:0019901 protein kinase binding 22.2222 5 no
GO:0046872 metal ion binding 22.2222 4 no
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 22.2222 4 no
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 22.2222 5 no
GO:0140297 DNA-binding transcription factor binding 22.2222 4 no
GO:0003690 double-stranded DNA binding 22.2222 5 no
GO:0015631 tubulin binding 22.2222 4 no
GO:0043565 sequence-specific DNA binding 22.2222 5 no
GO:0045296 cadherin binding 22.2222 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in PRR12_HUMAN
GO:0060255 regulation of macromolecule metabolic process 77.7778 4 no
GO:0031323 regulation of cellular metabolic process 66.6667 4 no
GO:0051171 regulation of nitrogen compound metabolic process 66.6667 4 no
GO:0080090 regulation of primary metabolic process 66.6667 4 no
GO:0009889 regulation of biosynthetic process 55.5556 4 no
GO:0009892 negative regulation of metabolic process 55.5556 4 no
GO:0010556 regulation of macromolecule biosynthetic process 55.5556 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 55.5556 5 no
GO:0031324 negative regulation of cellular metabolic process 55.5556 5 no
GO:0031326 regulation of cellular biosynthetic process 55.5556 5 no
GO:0048523 negative regulation of cellular process 55.5556 4 no
GO:0010468 regulation of gene expression 55.5556 5 no
GO:0009893 positive regulation of metabolic process 44.4444 4 no
GO:0010604 positive regulation of macromolecule metabolic process 44.4444 5 no
GO:0010605 negative regulation of macromolecule metabolic process 44.4444 5 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 44.4444 6 no
GO:0051172 negative regulation of nitrogen compound metabolic process 44.4444 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 44.4444 5 no
GO:0051252 regulation of RNA metabolic process 44.4444 5 no
GO:1903506 regulation of nucleic acid-templated transcription 44.4444 7 no
GO:2001141 regulation of RNA biosynthetic process 44.4444 6 no
GO:0022607 cellular component assembly 44.4444 4 no
GO:0036211 protein modification process 44.4444 4 no
GO:0043412 macromolecule modification 44.4444 4 no
GO:0048522 positive regulation of cellular process 44.4444 4 no
GO:0006355 regulation of DNA-templated transcription 44.4444 6 no
GO:0009890 negative regulation of biosynthetic process 33.3333 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 33.3333 6 no
GO:0031327 negative regulation of cellular biosynthetic process 33.3333 6 no
GO:0045892 negative regulation of DNA-templated transcription 33.3333 7 no
GO:0051246 regulation of protein metabolic process 33.3333 5 no
GO:0051247 positive regulation of protein metabolic process 33.3333 6 no
GO:0051253 negative regulation of RNA metabolic process 33.3333 6 no
GO:0051726 regulation of cell cycle 33.3333 4 no
GO:1902679 negative regulation of RNA biosynthetic process 33.3333 7 no
GO:1903507 negative regulation of nucleic acid-templated transcription 33.3333 8 no
GO:0009891 positive regulation of biosynthetic process 33.3333 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 33.3333 6 no
GO:0031325 positive regulation of cellular metabolic process 33.3333 5 no
GO:0031328 positive regulation of cellular biosynthetic process 33.3333 6 no
GO:0042127 regulation of cell population proliferation 33.3333 4 no
GO:0006357 regulation of transcription by RNA polymerase II 33.3333 7 no
GO:0031399 regulation of protein modification process 22.2222 6 no
GO:0031401 positive regulation of protein modification process 22.2222 7 no
GO:0006259 DNA metabolic process 22.2222 4 no
GO:0006281 DNA repair 22.2222 5 no
GO:0006974 cellular response to DNA damage stimulus 22.2222 4 no
GO:0006996 organelle organization 22.2222 4 no
GO:0007010 cytoskeleton organization 22.2222 5 no
GO:0007052 mitotic spindle organization 22.2222 4 no
GO:0051052 regulation of DNA metabolic process 22.2222 5 no
GO:0051225 spindle assembly 22.2222 4 no
GO:0070925 organelle assembly 22.2222 5 no
GO:0090304 nucleic acid metabolic process 22.2222 4 no
GO:0090307 mitotic spindle assembly 22.2222 5 no
GO:0140694 non-membrane-bounded organelle assembly 22.2222 6 no
GO:1902850 microtubule cytoskeleton organization involved in mitosis 22.2222 4 no
GO:0045893 positive regulation of DNA-templated transcription 22.2222 7 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 22.2222 6 no
GO:0051254 positive regulation of RNA metabolic process 22.2222 6 no
GO:1902680 positive regulation of RNA biosynthetic process 22.2222 7 no
GO:1903508 positive regulation of nucleic acid-templated transcription 22.2222 8 no
GO:0010564 regulation of cell cycle process 22.2222 5 no
GO:0010948 negative regulation of cell cycle process 22.2222 6 no
GO:0043933 protein-containing complex organization 22.2222 4 no
GO:0045786 negative regulation of cell cycle 22.2222 5 no
GO:0051091 positive regulation of DNA-binding transcription factor activity 22.2222 4 no
GO:0051259 protein complex oligomerization 22.2222 6 no
GO:0051260 protein homooligomerization 22.2222 7 no
GO:0065003 protein-containing complex assembly 22.2222 5 no
GO:0006796 phosphate-containing compound metabolic process 22.2222 4 no
GO:0051094 positive regulation of developmental process 22.2222 4 no
GO:0051240 positive regulation of multicellular organismal process 22.2222 4 no
GO:0000122 negative regulation of transcription by RNA polymerase II 22.2222 8 no
GO:0008285 negative regulation of cell population proliferation 22.2222 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
KEAP1_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
H2B2E_HUMAN [view interactions] High throughput no yes
NCBP3_HUMAN [view interactions] High throughput no yes
NCBP2_HUMAN [view interactions] High throughput no yes
HDAC4_HUMAN [view interactions] High throughput no yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
PUM1_HUMAN [view interactions] High throughput no yes
ESR1_HUMAN [view interactions] High throughput no no
TP53B_HUMAN [view entry] [view interactions] High throughput yes yes
ANDR_HUMAN [view interactions] High throughput no no
TBXT_HUMAN [view interactions] High throughput no no
ERG_HUMAN [view interactions] High throughput no yes
ETV4_HUMAN [view interactions] High throughput no yes
FEV_HUMAN [view interactions] High throughput no no
FOXI1_HUMAN [view interactions] High throughput no no
FOXL1_HUMAN [view interactions] High throughput no no
GATA2_HUMAN [view interactions] High throughput no yes
GATA3_HUMAN [view interactions] High throughput no no
GCM1_HUMAN [view interactions] High throughput no no
HNF1B_HUMAN [view interactions] High throughput no no
HNF4A_HUMAN [view interactions] High throughput no no
IRF4_HUMAN [view interactions] High throughput no no
IRF8_HUMAN [view interactions] High throughput no no
KLF15_HUMAN [view interactions] High throughput no yes
KLF5_HUMAN [view interactions] High throughput no yes
KLF8_HUMAN [view interactions] High throughput no no
LHX3_HUMAN [view interactions] High throughput no no
MYOD1_HUMAN [view interactions] High throughput no no
NFIA_HUMAN [view interactions] High throughput no yes
NFIB_HUMAN [view interactions] High throughput no yes
NFIC_HUMAN [view interactions] High throughput no yes
NFIX_HUMAN [view interactions] High throughput no yes
PAX2_HUMAN [view interactions] High throughput no no
PAX6_HUMAN [view interactions] High throughput no no
PAX7_HUMAN [view interactions] High throughput no no
PAX8_HUMAN [view interactions] High throughput no yes
PAX9_HUMAN [view interactions] High throughput no no
SOX15_HUMAN [view interactions] High throughput no no
SOX17_HUMAN [view interactions] High throughput no no
SOX2_HUMAN [view interactions] High throughput no yes
SOX9_HUMAN [view interactions] High throughput no no
SP7_HUMAN [view interactions] High throughput no no
TBR1_HUMAN [view interactions] High throughput no yes
TEAD1_HUMAN [view interactions] High throughput no no
TLX1_HUMAN [view interactions] High throughput no no
TLX2_HUMAN [view interactions] High throughput no no
TLX3_HUMAN [view interactions] High throughput no no
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
SOX7_HUMAN [view entry] [view interactions] High throughput yes yes
SODC_HUMAN [view interactions] High throughput no yes
MD2L1_HUMAN [view interactions] High throughput no no
NICA_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
MD2L2_HUMAN [view interactions] High throughput no yes
PP1G_HUMAN [view entry] [view interactions] High throughput yes yes
H4_HUMAN [view interactions] High throughput no yes
SMC1A_HUMAN [view interactions] High throughput no yes
SMC3_HUMAN [view entry] [view interactions] High throughput yes yes
STAG2_HUMAN [view interactions] High throughput no yes
SCC4_HUMAN [view interactions] High throughput no no
ECT2_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
FGL1_HUMAN [view interactions] High throughput no no
RHG12_HUMAN [view interactions] High throughput no yes
CBX1_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
UBP7_HUMAN [view interactions] High throughput no yes
RINI_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
ALG13_HUMAN [view interactions] High throughput no yes
SMG7_HUMAN [view interactions] High throughput no no
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
GOGA2_HUMAN [view entry] [view interactions] High throughput yes yes
TMG2_HUMAN [view interactions] Computational no yes
SFR19_HUMAN [view interactions] Computational no yes