PRR12_HUMAN
Evidence for PS localization
Functions
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 1169 | Arg | Trp | Neuroocularsyndrome(NOC) | - |
| 1970 | Leu | Pro | Neuroocularsyndrome(NOC) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PRR12_HUMAN |
|---|---|---|---|---|
| GO:0003677 | DNA binding | 30.0000 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PRR12_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 70.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 60.0000 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 60.0000 | 5 | no |
| GO:0031323 | regulation of cellular metabolic process | 60.0000 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 60.0000 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 60.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 60.0000 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 50.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 50.0000 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 50.0000 | 5 | no |
| GO:0022607 | cellular component assembly | 40.0000 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 40.0000 | 5 | no |
| GO:0036211 | protein modification process | 40.0000 | 4 | no |
| GO:0043412 | macromolecule modification | 40.0000 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 40.0000 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 40.0000 | 7 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 40.0000 | 5 | no |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 40.0000 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 40.0000 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 40.0000 | 6 | no |
| GO:0006996 | organelle organization | 30.0000 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 30.0000 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 30.0000 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 30.0000 | 6 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 30.0000 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 30.0000 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 30.0000 | 6 | no |
| GO:0043933 | protein-containing complex organization | 30.0000 | 4 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 30.0000 | 8 | no |
| GO:0009890 | negative regulation of biosynthetic process | 30.0000 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 30.0000 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 30.0000 | 6 | no |
| GO:0045892 | negative regulation of DNA-templated transcription | 30.0000 | 8 | no |
| GO:0051253 | negative regulation of RNA metabolic process | 30.0000 | 6 | no |
| GO:0051726 | regulation of cell cycle | 30.0000 | 4 | no |
| GO:1902679 | negative regulation of RNA biosynthetic process | 30.0000 | 7 | no |
| GO:0042127 | regulation of cell population proliferation | 30.0000 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NEK4_HUMAN | [view interactions] | High throughput | no | yes |
| H2B2E_HUMAN | [view interactions] | High throughput | no | yes |
| NCBP3_HUMAN | [view interactions] | High throughput | no | yes |
| NCBP2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PUM1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| TP53B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| TBXT_HUMAN | [view interactions] | High throughput | no | no |
| ERG_HUMAN | [view interactions] | High throughput | no | yes |
| ETV4_HUMAN | [view interactions] | High throughput | no | yes |
| FEV_HUMAN | [view interactions] | High throughput | no | no |
| FOXI1_HUMAN | [view interactions] | High throughput | no | no |
| FOXL1_HUMAN | [view interactions] | High throughput | no | no |
| GATA2_HUMAN | [view interactions] | High throughput | no | yes |
| GATA3_HUMAN | [view interactions] | High throughput | no | no |
| GCM1_HUMAN | [view interactions] | High throughput | no | no |
| HNF1B_HUMAN | [view interactions] | High throughput | no | no |
| HNF4A_HUMAN | [view interactions] | High throughput | no | no |
| IRF4_HUMAN | [view interactions] | High throughput | no | no |
| IRF8_HUMAN | [view interactions] | High throughput | no | no |
| KLF15_HUMAN | [view interactions] | High throughput | no | yes |
| KLF5_HUMAN | [view interactions] | High throughput | no | yes |
| KLF8_HUMAN | [view interactions] | High throughput | no | no |
| LHX3_HUMAN | [view interactions] | High throughput | no | no |
| MYOD1_HUMAN | [view interactions] | High throughput | no | no |
| NFIA_HUMAN | [view interactions] | High throughput | no | yes |
| NFIB_HUMAN | [view interactions] | High throughput | no | yes |
| NFIC_HUMAN | [view interactions] | High throughput | no | yes |
| NFIX_HUMAN | [view interactions] | High throughput | no | yes |
| PAX2_HUMAN | [view interactions] | High throughput | no | no |
| PAX6_HUMAN | [view interactions] | High throughput | no | no |
| PAX7_HUMAN | [view interactions] | High throughput | no | no |
| PAX8_HUMAN | [view interactions] | High throughput | no | yes |
| PAX9_HUMAN | [view interactions] | High throughput | no | no |
| SOX15_HUMAN | [view interactions] | High throughput | no | no |
| SOX17_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SOX9_HUMAN | [view interactions] | High throughput | no | no |
| SP7_HUMAN | [view interactions] | High throughput | no | no |
| TBR1_HUMAN | [view interactions] | High throughput | no | yes |
| TEAD1_HUMAN | [view interactions] | High throughput | no | no |
| TLX1_HUMAN | [view interactions] | High throughput | no | no |
| TLX2_HUMAN | [view interactions] | High throughput | no | no |
| TLX3_HUMAN | [view interactions] | High throughput | no | no |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L1_HUMAN | [view interactions] | High throughput | no | no |
| NICA_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| SMC1A_HUMAN | [view interactions] | High throughput | no | yes |
| SMC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAG2_HUMAN | [view interactions] | High throughput | no | yes |
| SCC4_HUMAN | [view interactions] | High throughput | no | no |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| FGL1_HUMAN | [view interactions] | High throughput | no | no |
| RHG12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBX1_HUMAN | [view interactions] | High throughput | no | yes |
| MEN1_HUMAN | [view interactions] | High throughput | no | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| RINI_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| ALG13_HUMAN | [view interactions] | High throughput | no | yes |
| SMG7_HUMAN | [view interactions] | High throughput | no | no |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUP35_HUMAN | [view interactions] | High throughput | no | yes |
| DTX2_HUMAN | [view interactions] | High throughput | no | yes |
| TLE3_HUMAN | [view interactions] | High throughput | no | yes |
| CRX_HUMAN | [view interactions] | High throughput | no | no |
| EGR2_HUMAN | [view interactions] | High throughput | no | no |
| GSC_HUMAN | [view interactions] | High throughput | no | no |
| EYA4_HUMAN | [view interactions] | High throughput | no | yes |