Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SMAG1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Acts as a translational repressor of SRE-containing messengers. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SMAG1_HUMAN
GO:0003723 RNA binding 44.4444 4 yes
GO:0045296 cadherin binding 33.3333 4 no
GO:0019900 kinase binding 22.2222 4 no
GO:0019901 protein kinase binding 22.2222 5 no
GO:0043169 cation binding 22.2222 4 no
GO:0046872 metal ion binding 22.2222 5 no
GO:0045309 protein phosphorylated amino acid binding 22.2222 4 no
GO:0050815 phosphoserine residue binding 22.2222 5 no
GO:0003729 mRNA binding 11.1111 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in SMAG1_HUMAN
GO:0060255 regulation of macromolecule metabolic process 94.4444 4 yes
GO:0080090 regulation of primary metabolic process 94.4444 4 yes
GO:0031323 regulation of cellular metabolic process 88.8889 4 yes
GO:0048523 negative regulation of cellular process 77.7778 4 yes
GO:0009889 regulation of biosynthetic process 66.6667 4 yes
GO:0009892 negative regulation of metabolic process 66.6667 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 66.6667 5 yes
GO:0031324 negative regulation of cellular metabolic process 66.6667 5 yes
GO:0031326 regulation of cellular biosynthetic process 66.6667 5 yes
GO:0051246 regulation of protein metabolic process 66.6667 5 yes
GO:0010468 regulation of gene expression 61.1111 6 yes
GO:0010605 negative regulation of macromolecule metabolic process 61.1111 5 yes
GO:0048522 positive regulation of cellular process 55.5556 4 yes
GO:0009890 negative regulation of biosynthetic process 44.4444 5 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 44.4444 6 yes
GO:0031327 negative regulation of cellular biosynthetic process 44.4444 6 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 44.4444 5 no
GO:0051252 regulation of RNA metabolic process 44.4444 5 no
GO:0008104 protein localization 44.4444 4 no
GO:0051128 regulation of cellular component organization 44.4444 4 no
GO:0009893 positive regulation of metabolic process 38.8889 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 38.8889 5 yes
GO:0031325 positive regulation of cellular metabolic process 38.8889 5 yes
GO:0031399 regulation of protein modification process 38.8889 6 no
GO:0006355 regulation of DNA-templated transcription 33.3333 7 no
GO:2001141 regulation of RNA biosynthetic process 33.3333 6 no
GO:0010646 regulation of cell communication 33.3333 4 no
GO:0051049 regulation of transport 33.3333 4 no
GO:0019220 regulation of phosphate metabolic process 33.3333 6 no
GO:0051174 regulation of phosphorus metabolic process 33.3333 5 no
GO:0009891 positive regulation of biosynthetic process 27.7778 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 27.7778 6 yes
GO:0031328 positive regulation of cellular biosynthetic process 27.7778 6 yes
GO:0051247 positive regulation of protein metabolic process 27.7778 6 yes
GO:0006996 organelle organization 27.7778 4 no
GO:0071702 organic substance transport 27.7778 4 no
GO:0071705 nitrogen compound transport 27.7778 4 no
GO:0009966 regulation of signal transduction 27.7778 4 no
GO:0010563 negative regulation of phosphorus metabolic process 27.7778 6 no
GO:0031400 negative regulation of protein modification process 27.7778 7 no
GO:0045936 negative regulation of phosphate metabolic process 27.7778 7 no
GO:0051248 negative regulation of protein metabolic process 27.7778 6 no
GO:0032880 regulation of protein localization 27.7778 5 no
GO:0060341 regulation of cellular localization 27.7778 4 no
GO:0006417 regulation of translation 22.2222 6 yes
GO:0010608 post-transcriptional regulation of gene expression 22.2222 7 yes
GO:0010629 negative regulation of gene expression 22.2222 7 yes
GO:0016070 RNA metabolic process 22.2222 5 yes
GO:0016071 mRNA metabolic process 22.2222 6 yes
GO:0090304 nucleic acid metabolic process 22.2222 4 yes
GO:1901361 organic cyclic compound catabolic process 22.2222 4 yes
GO:0021762 substantia nigra development 22.2222 4 no
GO:0045892 negative regulation of DNA-templated transcription 22.2222 8 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 22.2222 5 no
GO:0051253 negative regulation of RNA metabolic process 22.2222 6 no
GO:1902679 negative regulation of RNA biosynthetic process 22.2222 7 no
GO:0009894 regulation of catabolic process 22.2222 4 no
GO:0015031 protein transport 22.2222 4 no
GO:0034762 regulation of transmembrane transport 22.2222 4 no
GO:0034765 regulation of monoatomic ion transmembrane transport 22.2222 5 no
GO:0043269 regulation of monoatomic ion transport 22.2222 5 no
GO:0042981 regulation of apoptotic process 22.2222 5 no
GO:0043067 regulation of programmed cell death 22.2222 4 no
GO:0006605 protein targeting 22.2222 4 no
GO:0009968 negative regulation of signal transduction 22.2222 5 no
GO:0010648 negative regulation of cell communication 22.2222 5 no
GO:0023057 negative regulation of signaling 22.2222 4 no
GO:0048585 negative regulation of response to stimulus 22.2222 4 no
GO:0051726 regulation of cell cycle 22.2222 4 no
GO:0070201 regulation of establishment of protein localization 22.2222 6 no
GO:0001932 regulation of protein phosphorylation 22.2222 7 no
GO:0042325 regulation of phosphorylation 22.2222 7 no
GO:0000956 nuclear-transcribed mRNA catabolic process 16.6667 7 yes
GO:0006401 RNA catabolic process 16.6667 5 yes
GO:0006402 mRNA catabolic process 16.6667 6 yes
GO:0009057 macromolecule catabolic process 16.6667 4 yes
GO:0010628 positive regulation of gene expression 16.6667 7 yes
GO:0034655 nucleobase-containing compound catabolic process 16.6667 4 yes
GO:0141188 nucleic acid catabolic process 16.6667 5 yes
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 11.1111 8 yes
GO:0045727 positive regulation of translation 11.1111 7 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
1433G_HUMAN [view entry] [view interactions] Low throughput yes yes
SMAG1_HUMAN [view entry] [view interactions] Low throughput yes yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
1433S_HUMAN [view entry] [view interactions] High throughput yes yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
GOGA2_HUMAN [view entry] [view interactions] High throughput yes yes
NUTM1_HUMAN [view interactions] High throughput no no
RENT1_HUMAN [view entry] [view interactions] High throughput yes yes
SHIP2_HUMAN [view interactions] High throughput no yes
IF2B1_HUMAN [view interactions] High throughput no no
TNR6A_HUMAN [view interactions] High throughput no yes
CNOT2_HUMAN [view interactions] High throughput no yes
YTHD2_HUMAN [view interactions] High throughput no yes
TNR6B_HUMAN [view interactions] High throughput no yes
GRRE1_HUMAN [view interactions] High throughput no no
RGPD3_HUMAN [view interactions] High throughput no no
CEP85_HUMAN [view interactions] High throughput no no
CNOT1_HUMAN [view interactions] High throughput no yes
YTHD1_HUMAN [view interactions] High throughput no no
PUM1_HUMAN [view interactions] High throughput no yes
AKP8L_HUMAN [view interactions] High throughput no yes
PRDM6_HUMAN [view interactions] High throughput no no
MEOX2_HUMAN [view interactions] High throughput no no
AAKB2_HUMAN [view interactions] High throughput no yes
MTUS2_HUMAN [view interactions] High throughput no yes
BAG4_HUMAN [view interactions] High throughput no yes
HSF2B_HUMAN [view interactions] High throughput no yes
ANRA2_HUMAN [view interactions] High throughput no no
TBC21_HUMAN [view interactions] High throughput no no
IKBD_HUMAN [view interactions] High throughput no no
SMAG2_HUMAN [view interactions] High throughput no yes
TNIP1_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
DDB2_HUMAN [view interactions] High throughput no yes
CSDE1_HUMAN [view interactions] High throughput no yes
GAN_HUMAN [view interactions] High throughput no yes
PDP1_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
H4_HUMAN [view interactions] High throughput no yes
BASP1_HUMAN [view entry] [view interactions] High throughput yes yes
EPN4_HUMAN [view interactions] High throughput no yes
LIMC1_HUMAN [view entry] [view interactions] High throughput yes no
RS29_HUMAN [view interactions] High throughput no yes
RTCB_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
LRFN4_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
OTUD4_HUMAN [view interactions] High throughput no yes
LNP_HUMAN [view interactions] High throughput no yes
DCAF4_HUMAN [view interactions] High throughput no yes