Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PLLP_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective . [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PLLP_HUMAN
GO:0000166 nucleotide binding 36.3636 4 no
GO:0017076 purine nucleotide binding 36.3636 5 no
GO:0032555 purine ribonucleotide binding 36.3636 4 no
GO:0035639 purine ribonucleoside triphosphate binding 36.3636 4 no
GO:0043168 anion binding 36.3636 4 no
GO:0043169 cation binding 27.2727 4 no
GO:0003924 GTPase activity 27.2727 7 no
GO:0005525 GTP binding 27.2727 5 no
GO:0016462 pyrophosphatase activity 27.2727 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 27.2727 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 27.2727 6 no
GO:0019001 guanyl nucleotide binding 27.2727 6 no
GO:0032561 guanyl ribonucleotide binding 27.2727 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in PLLP_HUMAN
GO:0048522 positive regulation of cellular process 72.7273 4 no
GO:0051128 regulation of cellular component organization 54.5455 4 no
GO:0006996 organelle organization 45.4545 4 no
GO:0008104 protein localization 45.4545 4 no
GO:0032880 regulation of protein localization 45.4545 5 no
GO:0060341 regulation of cellular localization 45.4545 4 no
GO:0009889 regulation of biosynthetic process 45.4545 4 no
GO:0009891 positive regulation of biosynthetic process 45.4545 5 no
GO:0009893 positive regulation of metabolic process 45.4545 4 no
GO:0010468 regulation of gene expression 45.4545 6 no
GO:0010556 regulation of macromolecule biosynthetic process 45.4545 5 no
GO:0031323 regulation of cellular metabolic process 45.4545 4 no
GO:0031326 regulation of cellular biosynthetic process 45.4545 5 no
GO:0048523 negative regulation of cellular process 45.4545 4 no
GO:0060255 regulation of macromolecule metabolic process 45.4545 4 no
GO:0080090 regulation of primary metabolic process 45.4545 4 no
GO:0006811 monoatomic ion transport 36.3636 4 yes
GO:0051094 positive regulation of developmental process 36.3636 4 no
GO:0051130 positive regulation of cellular component organization 36.3636 5 no
GO:0033043 regulation of organelle organization 36.3636 5 no
GO:0070201 regulation of establishment of protein localization 36.3636 6 no
GO:0009892 negative regulation of metabolic process 36.3636 4 no
GO:0010605 negative regulation of macromolecule metabolic process 36.3636 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 36.3636 5 no
GO:0031324 negative regulation of cellular metabolic process 36.3636 5 no
GO:0042981 regulation of apoptotic process 36.3636 5 no
GO:0043067 regulation of programmed cell death 36.3636 4 no
GO:0071702 organic substance transport 36.3636 4 no
GO:0071705 nitrogen compound transport 36.3636 4 no
GO:0098657 import into cell 36.3636 4 no
GO:0009966 regulation of signal transduction 36.3636 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 36.3636 6 no
GO:0010604 positive regulation of macromolecule metabolic process 36.3636 5 no
GO:0010628 positive regulation of gene expression 36.3636 7 no
GO:0010646 regulation of cell communication 36.3636 4 no
GO:0031325 positive regulation of cellular metabolic process 36.3636 5 no
GO:0031328 positive regulation of cellular biosynthetic process 36.3636 6 no
GO:0042127 regulation of cell population proliferation 36.3636 4 no
GO:0033365 protein localization to organelle 27.2727 5 no
GO:0072594 establishment of protein localization to organelle 27.2727 4 no
GO:1903829 positive regulation of protein localization 27.2727 5 no
GO:1904951 positive regulation of establishment of protein localization 27.2727 6 no
GO:0006355 regulation of DNA-templated transcription 27.2727 7 no
GO:0006357 regulation of transcription by RNA polymerase II 27.2727 8 no
GO:0006812 monoatomic cation transport 27.2727 5 no
GO:0009890 negative regulation of biosynthetic process 27.2727 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 27.2727 6 no
GO:0030001 metal ion transport 27.2727 6 no
GO:0031327 negative regulation of cellular biosynthetic process 27.2727 6 no
GO:0044057 regulation of system process 27.2727 4 no
GO:0045595 regulation of cell differentiation 27.2727 4 no
GO:0051241 negative regulation of multicellular organismal process 27.2727 4 no
GO:0051252 regulation of RNA metabolic process 27.2727 5 no
GO:0060284 regulation of cell development 27.2727 5 no
GO:0098655 monoatomic cation transmembrane transport 27.2727 4 no
GO:0098662 inorganic cation transmembrane transport 27.2727 4 no
GO:2001141 regulation of RNA biosynthetic process 27.2727 6 no
GO:0001932 regulation of protein phosphorylation 27.2727 7 no
GO:0008284 positive regulation of cell population proliferation 27.2727 5 no
GO:0008285 negative regulation of cell population proliferation 27.2727 5 no
GO:0009967 positive regulation of signal transduction 27.2727 5 no
GO:0010647 positive regulation of cell communication 27.2727 5 no
GO:0019220 regulation of phosphate metabolic process 27.2727 6 no
GO:0023056 positive regulation of signaling 27.2727 4 no
GO:0030334 regulation of cell migration 27.2727 5 no
GO:0031399 regulation of protein modification process 27.2727 6 no
GO:0042325 regulation of phosphorylation 27.2727 7 no
GO:0043066 negative regulation of apoptotic process 27.2727 6 no
GO:0043069 negative regulation of programmed cell death 27.2727 5 no
GO:0048168 regulation of neuronal synaptic plasticity 27.2727 4 no
GO:0048169 regulation of long-term neuronal synaptic plasticity 27.2727 5 no
GO:0048584 positive regulation of response to stimulus 27.2727 4 no
GO:0050804 modulation of chemical synaptic transmission 27.2727 5 no
GO:0051174 regulation of phosphorus metabolic process 27.2727 5 no
GO:0051240 positive regulation of multicellular organismal process 27.2727 4 no
GO:0051246 regulation of protein metabolic process 27.2727 5 no
GO:0080134 regulation of response to stress 27.2727 4 no
GO:0099177 regulation of trans-synaptic signaling 27.2727 4 no
GO:0141124 intracellular signaling cassette 27.2727 4 no
GO:1902531 regulation of intracellular signal transduction 27.2727 5 no
GO:1902533 positive regulation of intracellular signal transduction 27.2727 6 no
GO:2000145 regulation of cell motility 27.2727 4 no
GO:0051049 regulation of transport 27.2727 4 no
GO:0042552 myelination 18.1818 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CREB3_HUMAN [view interactions] High throughput no no
MMP14_HUMAN [view interactions] High throughput no yes
B2L13_HUMAN [view interactions] High throughput no no
M4A12_HUMAN [view interactions] High throughput no no
CRTP1_HUMAN [view interactions] High throughput no yes
GRN_HUMAN [view interactions] High throughput no no
PACC1_HUMAN [view interactions] High throughput no no
FRS3_HUMAN [view interactions] High throughput no no
KRT34_HUMAN [view interactions] High throughput no no
TRI59_HUMAN [view interactions] High throughput no no
TNF14_HUMAN [view interactions] High throughput no yes
KRA92_HUMAN [view interactions] High throughput no no
HXA1_HUMAN [view interactions] High throughput no no
GOT1A_HUMAN [view interactions] High throughput no no
TIGIT_HUMAN [view interactions] High throughput no no
TM174_HUMAN [view interactions] High throughput no no
KISHB_HUMAN [view interactions] High throughput no no
FNDC9_HUMAN [view interactions] High throughput no no
VMA21_HUMAN [view interactions] High throughput no no
CLD14_HUMAN [view interactions] High throughput no no
F174A_HUMAN [view interactions] High throughput no yes
EBP_HUMAN [view interactions] High throughput no no
KCNJ6_HUMAN [view entry] [view interactions] High throughput yes no
AQP6_HUMAN [view interactions] High throughput no no
STING_HUMAN [view interactions] High throughput no yes
TMPPE_HUMAN [view interactions] High throughput no yes
GPX8_HUMAN [view interactions] High throughput no no
LHPL5_HUMAN [view interactions] High throughput no no
TM14B_HUMAN [view interactions] High throughput no no
ZDH15_HUMAN [view entry] [view interactions] High throughput yes yes
ERGI3_HUMAN [view interactions] High throughput no yes
ELOV4_HUMAN [view interactions] High throughput no no
SOAT_HUMAN [view interactions] High throughput no no
RN122_HUMAN [view interactions] High throughput no yes
SAR1A_HUMAN [view entry] [view interactions] High throughput yes yes
PGRC2_HUMAN [view interactions] High throughput no yes
CCR2_HUMAN [view interactions] High throughput no yes
DRD2_HUMAN [view entry] [view interactions] High throughput yes no
GPR35_HUMAN [view interactions] High throughput no no
5HT2B_HUMAN [view interactions] High throughput no no
MC4R_HUMAN [view interactions] High throughput no yes
OPRX_HUMAN [view interactions] High throughput no no
PTAFR_HUMAN [view interactions] High throughput no yes
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
CLC2D_HUMAN [view interactions] High throughput no yes
CRUM3_HUMAN [view interactions] High throughput no no
SYPL2_HUMAN [view interactions] High throughput no no
MFF_HUMAN [view entry] [view interactions] High throughput yes yes
C16L2_HUMAN [view interactions] High throughput no no
TMPS2_HUMAN [view interactions] High throughput no no
KR101_HUMAN [view interactions] High throughput no no
CL12B_HUMAN [view interactions] High throughput no no
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
TRPV1_HUMAN [view entry] [view interactions] High throughput yes no
RIGI_HUMAN [view interactions] High throughput no yes
HBB_HUMAN [view interactions] High throughput no no
HBA_HUMAN [view interactions] High throughput no no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
RASK_HUMAN [view entry] [view interactions] High throughput yes no