Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RAB15_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in RAB15_HUMAN
GO:0000166 nucleotide binding 42.8571 4 yes
GO:0017076 purine nucleotide binding 35.7143 5 yes
GO:0032555 purine ribonucleotide binding 35.7143 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 35.7143 4 yes
GO:0043168 anion binding 35.7143 4 yes
GO:0016755 aminoacyltransferase activity 35.7143 4 no
GO:0005524 ATP binding 28.5714 5 no
GO:0030554 adenyl nucleotide binding 28.5714 6 no
GO:0032559 adenyl ribonucleotide binding 28.5714 5 no
GO:0004842 ubiquitin-protein transferase activity 28.5714 4 no
GO:0031625 ubiquitin protein ligase binding 28.5714 5 no
GO:0043169 cation binding 28.5714 4 no
GO:0044389 ubiquitin-like protein ligase binding 28.5714 4 no
GO:0046872 metal ion binding 28.5714 5 no
GO:0061630 ubiquitin protein ligase activity 21.4286 5 no
GO:0061659 ubiquitin-like protein ligase activity 21.4286 4 no
GO:0016462 pyrophosphatase activity 14.2857 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 14.2857 4 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 14.2857 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RAB15_HUMAN
GO:0048522 positive regulation of cellular process 64.2857 4 yes
GO:0022607 cellular component assembly 57.1429 4 no
GO:0060255 regulation of macromolecule metabolic process 57.1429 4 no
GO:0080090 regulation of primary metabolic process 57.1429 4 no
GO:0036211 protein modification process 50.0000 4 no
GO:0043412 macromolecule modification 50.0000 4 no
GO:0009893 positive regulation of metabolic process 50.0000 4 no
GO:0010604 positive regulation of macromolecule metabolic process 50.0000 5 no
GO:0031323 regulation of cellular metabolic process 50.0000 4 no
GO:0048523 negative regulation of cellular process 50.0000 4 no
GO:0051246 regulation of protein metabolic process 50.0000 5 no
GO:0051247 positive regulation of protein metabolic process 50.0000 6 no
GO:0043933 protein-containing complex organization 42.8571 4 no
GO:1902531 regulation of intracellular signal transduction 42.8571 5 no
GO:0008104 protein localization 42.8571 4 yes
GO:0051049 regulation of transport 42.8571 4 yes
GO:0051128 regulation of cellular component organization 42.8571 4 no
GO:0009892 negative regulation of metabolic process 42.8571 4 no
GO:0009966 regulation of signal transduction 42.8571 4 no
GO:0010605 negative regulation of macromolecule metabolic process 42.8571 5 no
GO:0010646 regulation of cell communication 42.8571 4 no
GO:0019941 modification-dependent protein catabolic process 35.7143 6 no
GO:0031324 negative regulation of cellular metabolic process 35.7143 5 no
GO:0031326 regulation of cellular biosynthetic process 35.7143 5 no
GO:0033365 protein localization to organelle 35.7143 5 no
GO:0042981 regulation of apoptotic process 35.7143 5 no
GO:0043067 regulation of programmed cell death 35.7143 4 no
GO:0043632 modification-dependent macromolecule catabolic process 35.7143 5 no
GO:0051252 regulation of RNA metabolic process 35.7143 5 no
GO:0051603 proteolysis involved in protein catabolic process 35.7143 5 no
GO:0065003 protein-containing complex assembly 35.7143 5 no
GO:0051050 positive regulation of transport 35.7143 4 yes
GO:0006996 organelle organization 35.7143 4 no
GO:0010564 regulation of cell cycle process 35.7143 5 no
GO:0031325 positive regulation of cellular metabolic process 35.7143 5 no
GO:0031399 regulation of protein modification process 35.7143 6 no
GO:0031401 positive regulation of protein modification process 35.7143 7 no
GO:0051726 regulation of cell cycle 35.7143 4 no
GO:0006508 proteolysis 35.7143 4 no
GO:0006511 ubiquitin-dependent protein catabolic process 35.7143 7 no
GO:0009057 macromolecule catabolic process 35.7143 4 no
GO:0009889 regulation of biosynthetic process 35.7143 4 no
GO:0010468 regulation of gene expression 35.7143 6 no
GO:0010556 regulation of macromolecule biosynthetic process 35.7143 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 35.7143 5 no
GO:0030163 protein catabolic process 28.5714 4 no
GO:0031327 negative regulation of cellular biosynthetic process 28.5714 6 no
GO:0032446 protein modification by small protein conjugation 28.5714 7 no
GO:0043687 post-translational protein modification 28.5714 5 no
GO:0045892 negative regulation of DNA-templated transcription 28.5714 8 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 28.5714 5 no
GO:0048584 positive regulation of response to stimulus 28.5714 4 no
GO:0051248 negative regulation of protein metabolic process 28.5714 6 no
GO:0051253 negative regulation of RNA metabolic process 28.5714 6 no
GO:0070647 protein modification by small protein conjugation or removal 28.5714 6 no
GO:0097435 supramolecular fiber organization 28.5714 4 no
GO:1901565 organonitrogen compound catabolic process 28.5714 4 no
GO:1902679 negative regulation of RNA biosynthetic process 28.5714 7 no
GO:2001141 regulation of RNA biosynthetic process 28.5714 6 no
GO:0051046 regulation of secretion 28.5714 5 yes
GO:1903530 regulation of secretion by cell 28.5714 4 yes
GO:0001932 regulation of protein phosphorylation 28.5714 7 no
GO:0007346 regulation of mitotic cell cycle 28.5714 5 no
GO:0019220 regulation of phosphate metabolic process 28.5714 6 no
GO:0042325 regulation of phosphorylation 28.5714 7 no
GO:0045787 positive regulation of cell cycle 28.5714 5 no
GO:0045931 positive regulation of mitotic cell cycle 28.5714 6 no
GO:0051174 regulation of phosphorus metabolic process 28.5714 5 no
GO:0090068 positive regulation of cell cycle process 28.5714 6 no
GO:0000122 negative regulation of transcription by RNA polymerase II 28.5714 9 no
GO:0006355 regulation of DNA-templated transcription 28.5714 7 no
GO:0006357 regulation of transcription by RNA polymerase II 28.5714 8 no
GO:0009890 negative regulation of biosynthetic process 28.5714 5 no
GO:0009894 regulation of catabolic process 28.5714 4 no
GO:0010498 proteasomal protein catabolic process 28.5714 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 28.5714 6 no
GO:0010629 negative regulation of gene expression 28.5714 7 no
GO:0023056 positive regulation of signaling 21.4286 4 no
GO:0023057 negative regulation of signaling 21.4286 4 no
GO:0030162 regulation of proteolysis 21.4286 6 no
GO:0031648 protein destabilization 21.4286 4 no
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 21.4286 6 no
GO:0032880 regulation of protein localization 21.4286 5 no
GO:0033043 regulation of organelle organization 21.4286 5 no
GO:0042176 regulation of protein catabolic process 21.4286 5 no
GO:0043066 negative regulation of apoptotic process 21.4286 6 no
GO:0043069 negative regulation of programmed cell death 21.4286 5 no
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 21.4286 6 no
GO:0043408 regulation of MAPK cascade 21.4286 6 no
GO:0043549 regulation of kinase activity 21.4286 5 no
GO:0045732 positive regulation of protein catabolic process 21.4286 6 no
GO:0045862 positive regulation of proteolysis 21.4286 7 no
GO:0048585 negative regulation of response to stimulus 21.4286 4 no
GO:0051094 positive regulation of developmental process 21.4286 4 no
GO:0051130 positive regulation of cellular component organization 21.4286 5 no
GO:0051223 regulation of protein transport 21.4286 5 no
GO:0051338 regulation of transferase activity 21.4286 4 no
GO:0051865 protein autoubiquitination 21.4286 9 no
GO:0060341 regulation of cellular localization 21.4286 4 no
GO:0061136 regulation of proteasomal protein catabolic process 21.4286 6 no
GO:0070201 regulation of establishment of protein localization 21.4286 6 no
GO:0071310 cellular response to organic substance 21.4286 4 no
GO:0080134 regulation of response to stress 21.4286 4 no
GO:0080135 regulation of cellular response to stress 21.4286 4 no
GO:1901701 cellular response to oxygen-containing compound 21.4286 4 no
GO:1901800 positive regulation of proteasomal protein catabolic process 21.4286 7 no
GO:1902532 negative regulation of intracellular signal transduction 21.4286 6 no
GO:1902533 positive regulation of intracellular signal transduction 21.4286 6 no
GO:1903050 regulation of proteolysis involved in protein catabolic process 21.4286 7 no
GO:1903052 positive regulation of proteolysis involved in protein catabolic process 21.4286 8 no
GO:2000058 regulation of ubiquitin-dependent protein catabolic process 21.4286 5 no
GO:2001233 regulation of apoptotic signaling pathway 21.4286 5 no
GO:0008284 positive regulation of cell population proliferation 21.4286 5 no
GO:0018193 peptidyl-amino acid modification 21.4286 5 no
GO:0042127 regulation of cell population proliferation 21.4286 4 no
GO:0044057 regulation of system process 21.4286 4 no
GO:0006915 apoptotic process 21.4286 4 no
GO:0071702 organic substance transport 21.4286 4 yes
GO:0071705 nitrogen compound transport 21.4286 4 yes
GO:0141124 intracellular signaling cassette 21.4286 4 yes
GO:0048232 male gamete generation 21.4286 4 no
GO:0001934 positive regulation of protein phosphorylation 21.4286 8 no
GO:0010562 positive regulation of phosphorus metabolic process 21.4286 6 no
GO:0042327 positive regulation of phosphorylation 21.4286 8 no
GO:0045937 positive regulation of phosphate metabolic process 21.4286 7 no
GO:0051129 negative regulation of cellular component organization 21.4286 5 no
GO:1901987 regulation of cell cycle phase transition 21.4286 6 no
GO:1901989 positive regulation of cell cycle phase transition 21.4286 7 no
GO:1901990 regulation of mitotic cell cycle phase transition 21.4286 6 no
GO:1901992 positive regulation of mitotic cell cycle phase transition 21.4286 7 no
GO:0000209 protein polyubiquitination 21.4286 9 no
GO:0009896 positive regulation of catabolic process 21.4286 5 no
GO:0009967 positive regulation of signal transduction 21.4286 5 no
GO:0009968 negative regulation of signal transduction 21.4286 5 no
GO:0010038 response to metal ion 21.4286 4 no
GO:0010647 positive regulation of cell communication 21.4286 5 no
GO:0010648 negative regulation of cell communication 21.4286 5 no
GO:0016567 protein ubiquitination 21.4286 8 no
GO:0017157 regulation of exocytosis 14.2857 5 yes
GO:0051047 positive regulation of secretion 14.2857 5 yes
GO:0060627 regulation of vesicle-mediated transport 14.2857 4 yes
GO:1903532 positive regulation of secretion by cell 14.2857 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
MSS4_HUMAN [view interactions] Low throughput no yes
GBRL1_HUMAN [view interactions] High throughput no yes
GDS1_HUMAN [view entry] [view interactions] High throughput yes yes
TOIP2_HUMAN [view interactions] High throughput no no
CFTR_HUMAN [view interactions] High throughput no no
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CD177_HUMAN [view interactions] High throughput no no
RYBP_HUMAN [view interactions] High throughput no no
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
CDK2_HUMAN [view interactions] High throughput no yes
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
FGFR1_HUMAN [view entry] [view interactions] High throughput yes yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
HEXI1_HUMAN [view interactions] High throughput no yes
BAG6_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
AGR2_HUMAN [view interactions] High throughput no no
H2AB1_HUMAN [view interactions] High throughput no no
MILK1_HUMAN [view interactions] High throughput no yes
HSP72_HUMAN [view entry] [view interactions] High throughput yes no
MDM2_HUMAN [view entry] [view interactions] High throughput yes yes
HERC1_HUMAN [view interactions] High throughput no no
OBI1_HUMAN [view interactions] High throughput no yes
SEN15_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
GOLI_HUMAN [view interactions] High throughput no yes
RN149_HUMAN [view interactions] High throughput no no
TNIP1_HUMAN [view interactions] High throughput no yes
ACACA_HUMAN [view entry] [view interactions] High throughput yes yes
VDAC3_HUMAN [view entry] [view interactions] High throughput yes yes
RN183_HUMAN [view interactions] High throughput no no