Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PPID_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

(Microbial infection) May be involved in hepatitis C virus (HCV) replication and release. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PPID_HUMAN
GO:0003723 RNA binding 41.1765 4 no
GO:0043168 anion binding 38.2353 4 no
GO:0000166 nucleotide binding 35.2941 4 no
GO:0017076 purine nucleotide binding 35.2941 5 no
GO:0032555 purine ribonucleotide binding 35.2941 4 no
GO:0035639 purine ribonucleoside triphosphate binding 35.2941 4 no
GO:0005524 ATP binding 29.4118 5 no
GO:0019900 kinase binding 29.4118 4 no
GO:0019901 protein kinase binding 29.4118 5 no
GO:0030554 adenyl nucleotide binding 29.4118 6 no
GO:0032559 adenyl ribonucleotide binding 29.4118 5 no
GO:0031625 ubiquitin protein ligase binding 20.5882 5 no
GO:0044389 ubiquitin-like protein ligase binding 20.5882 4 no
GO:0043169 cation binding 20.5882 4 no
GO:0046872 metal ion binding 20.5882 5 no
GO:0003677 DNA binding 20.5882 4 no
GO:0051879 Hsp90 protein binding 17.6471 4 yes
GO:0140297 DNA-binding transcription factor binding 17.6471 4 yes
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 14.7059 5 yes
GO:0030544 Hsp70 protein binding 8.8235 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PPID_HUMAN
GO:0048522 positive regulation of cellular process 70.5882 4 yes
GO:0048523 negative regulation of cellular process 61.7647 4 yes
GO:0060255 regulation of macromolecule metabolic process 58.8235 4 yes
GO:0080090 regulation of primary metabolic process 58.8235 4 yes
GO:0051128 regulation of cellular component organization 58.8235 4 no
GO:0031323 regulation of cellular metabolic process 55.8824 4 yes
GO:0009889 regulation of biosynthetic process 52.9412 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 52.9412 5 yes
GO:0031326 regulation of cellular biosynthetic process 52.9412 5 yes
GO:0010646 regulation of cell communication 52.9412 4 no
GO:0009966 regulation of signal transduction 50.0000 4 no
GO:0006996 organelle organization 47.0588 4 yes
GO:0010468 regulation of gene expression 47.0588 6 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 47.0588 5 yes
GO:0009893 positive regulation of metabolic process 47.0588 4 no
GO:0071310 cellular response to organic substance 47.0588 4 no
GO:0048584 positive regulation of response to stimulus 44.1176 4 no
GO:0009892 negative regulation of metabolic process 44.1176 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 44.1176 5 yes
GO:0051049 regulation of transport 44.1176 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 44.1176 5 no
GO:0051246 regulation of protein metabolic process 44.1176 5 no
GO:0010647 positive regulation of cell communication 41.1765 5 no
GO:0023056 positive regulation of signaling 41.1765 4 no
GO:0022607 cellular component assembly 41.1765 4 yes
GO:0042981 regulation of apoptotic process 41.1765 5 yes
GO:0043067 regulation of programmed cell death 41.1765 4 yes
GO:0043933 protein-containing complex organization 41.1765 4 yes
GO:0031325 positive regulation of cellular metabolic process 41.1765 5 no
GO:0044087 regulation of cellular component biogenesis 41.1765 4 no
GO:1902531 regulation of intracellular signal transduction 38.2353 5 no
GO:0006355 regulation of DNA-templated transcription 38.2353 7 yes
GO:0009890 negative regulation of biosynthetic process 38.2353 5 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 38.2353 6 yes
GO:0031324 negative regulation of cellular metabolic process 38.2353 5 yes
GO:0031327 negative regulation of cellular biosynthetic process 38.2353 6 yes
GO:0051252 regulation of RNA metabolic process 38.2353 5 yes
GO:0060341 regulation of cellular localization 38.2353 4 yes
GO:2001141 regulation of RNA biosynthetic process 38.2353 6 yes
GO:0033043 regulation of organelle organization 38.2353 5 no
GO:0051130 positive regulation of cellular component organization 38.2353 5 no
GO:0051247 positive regulation of protein metabolic process 38.2353 6 no
GO:0009967 positive regulation of signal transduction 35.2941 5 no
GO:0051240 positive regulation of multicellular organismal process 35.2941 4 no
GO:0009891 positive regulation of biosynthetic process 35.2941 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 35.2941 6 no
GO:0031328 positive regulation of cellular biosynthetic process 35.2941 6 no
GO:0080134 regulation of response to stress 35.2941 4 no
GO:0031399 regulation of protein modification process 32.3529 6 no
GO:0045595 regulation of cell differentiation 32.3529 4 no
GO:0002684 positive regulation of immune system process 29.4118 4 no
GO:0014070 response to organic cyclic compound 29.4118 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 29.4118 5 no
GO:0032880 regulation of protein localization 29.4118 5 yes
GO:0036211 protein modification process 29.4118 4 yes
GO:0043412 macromolecule modification 29.4118 4 yes
GO:0065003 protein-containing complex assembly 29.4118 5 yes
GO:0006796 phosphate-containing compound metabolic process 29.4118 4 no
GO:0009894 regulation of catabolic process 29.4118 4 no
GO:0010638 positive regulation of organelle organization 29.4118 6 no
GO:0034097 response to cytokine 29.4118 4 no
GO:1901701 cellular response to oxygen-containing compound 26.4706 4 no
GO:0090304 nucleic acid metabolic process 26.4706 4 no
GO:0042127 regulation of cell population proliferation 26.4706 4 no
GO:0006357 regulation of transcription by RNA polymerase II 26.4706 8 yes
GO:0008104 protein localization 26.4706 4 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 26.4706 5 yes
GO:0051050 positive regulation of transport 26.4706 4 yes
GO:0019220 regulation of phosphate metabolic process 26.4706 6 no
GO:0043254 regulation of protein-containing complex assembly 26.4706 5 no
GO:0044089 positive regulation of cellular component biogenesis 26.4706 5 no
GO:0045597 positive regulation of cell differentiation 26.4706 5 no
GO:0051094 positive regulation of developmental process 26.4706 4 no
GO:0051129 negative regulation of cellular component organization 26.4706 5 no
GO:0051174 regulation of phosphorus metabolic process 26.4706 5 no
GO:0051338 regulation of transferase activity 26.4706 4 no
GO:1902533 positive regulation of intracellular signal transduction 23.5294 6 no
GO:0042325 regulation of phosphorylation 23.5294 7 no
GO:0006915 apoptotic process 23.5294 4 yes
GO:0051253 negative regulation of RNA metabolic process 23.5294 6 yes
GO:0071702 organic substance transport 23.5294 4 yes
GO:0071705 nitrogen compound transport 23.5294 4 yes
GO:1903829 positive regulation of protein localization 23.5294 5 yes
GO:0010628 positive regulation of gene expression 23.5294 7 no
GO:0030030 cell projection organization 23.5294 4 no
GO:0032886 regulation of microtubule-based process 23.5294 4 no
GO:0033993 response to lipid 23.5294 4 no
GO:0043066 negative regulation of apoptotic process 23.5294 6 no
GO:0043069 negative regulation of programmed cell death 23.5294 5 no
GO:0043085 positive regulation of catalytic activity 23.5294 4 no
GO:0051248 negative regulation of protein metabolic process 23.5294 6 no
GO:0051493 regulation of cytoskeleton organization 23.5294 6 no
GO:0060284 regulation of cell development 23.5294 5 no
GO:0071345 cellular response to cytokine stimulus 23.5294 5 no
GO:0080135 regulation of cellular response to stress 23.5294 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 20.5882 6 no
GO:1901873 regulation of post-translational protein modification 20.5882 7 no
GO:1903320 regulation of protein modification by small protein conjugation or removal 20.5882 8 no
GO:2001233 regulation of apoptotic signaling pathway 20.5882 5 no
GO:0001932 regulation of protein phosphorylation 20.5882 7 no
GO:0043549 regulation of kinase activity 20.5882 5 no
GO:0030705 cytoskeleton-dependent intracellular transport 20.5882 4 no
GO:0051726 regulation of cell cycle 20.5882 4 no
GO:0071407 cellular response to organic cyclic compound 20.5882 5 no
GO:1902903 regulation of supramolecular fiber organization 20.5882 5 no
GO:2000026 regulation of multicellular organismal development 20.5882 4 no
GO:0015031 protein transport 20.5882 4 yes
GO:0045892 negative regulation of DNA-templated transcription 20.5882 8 yes
GO:0070201 regulation of establishment of protein localization 20.5882 6 yes
GO:1902679 negative regulation of RNA biosynthetic process 20.5882 7 yes
GO:0007005 mitochondrion organization 20.5882 5 no
GO:0009057 macromolecule catabolic process 20.5882 4 no
GO:0009896 positive regulation of catabolic process 20.5882 5 no
GO:0010629 negative regulation of gene expression 20.5882 7 no
GO:0010648 negative regulation of cell communication 20.5882 5 no
GO:0023057 negative regulation of signaling 20.5882 4 no
GO:0030162 regulation of proteolysis 20.5882 6 no
GO:0031334 positive regulation of protein-containing complex assembly 20.5882 6 no
GO:0031344 regulation of cell projection organization 20.5882 5 no
GO:0031396 regulation of protein ubiquitination 20.5882 9 no
GO:0031401 positive regulation of protein modification process 20.5882 7 no
GO:0048585 negative regulation of response to stimulus 20.5882 4 no
GO:0050804 modulation of chemical synaptic transmission 20.5882 5 no
GO:0051336 regulation of hydrolase activity 20.5882 4 no
GO:0071396 cellular response to lipid 20.5882 5 no
GO:0099177 regulation of trans-synaptic signaling 20.5882 4 no
GO:0018193 peptidyl-amino acid modification 17.6471 5 yes
GO:0051046 regulation of secretion 17.6471 5 yes
GO:0051223 regulation of protein transport 17.6471 5 yes
GO:1903530 regulation of secretion by cell 17.6471 4 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 14.7059 9 yes
GO:0009416 response to light stimulus 14.7059 4 yes
GO:0051222 positive regulation of protein transport 14.7059 5 yes
GO:1904951 positive regulation of establishment of protein localization 14.7059 6 yes
GO:0043065 positive regulation of apoptotic process 11.7647 6 yes
GO:0043068 positive regulation of programmed cell death 11.7647 5 yes
GO:0051047 positive regulation of secretion 11.7647 5 yes
GO:1903532 positive regulation of secretion by cell 11.7647 5 yes
GO:0009411 response to UV 8.8235 5 yes
GO:0034644 cellular response to UV 8.8235 6 yes
GO:0050708 regulation of protein secretion 8.8235 5 yes
GO:0050714 positive regulation of protein secretion 8.8235 6 yes
GO:0071478 cellular response to radiation 8.8235 4 yes
GO:0071482 cellular response to light stimulus 8.8235 5 yes
GO:1903900 regulation of viral life cycle 5.8824 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ILF2_HUMAN [view interactions] Low throughput no yes
RS3_HUMAN [view entry] [view interactions] Low throughput yes yes
RACK1_HUMAN [view interactions] Low throughput no yes
XRCC6_HUMAN [view interactions] Low throughput no yes
MK01_HUMAN [view entry] [view interactions] Low throughput yes yes
ATPO_HUMAN [view interactions] Low throughput no yes
S10A6_HUMAN [view interactions] Low throughput no yes
GSK3B_HUMAN [view entry] [view interactions] Low throughput yes yes
A4_HUMAN [view entry] [view interactions] Low throughput yes yes
HS90A_HUMAN [view entry] [view interactions] Low throughput yes yes
HS90B_HUMAN [view entry] [view interactions] Low throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] Low throughput yes yes
BCL2_HUMAN [view interactions] Low throughput no no
S10A1_HUMAN [view interactions] Low throughput no yes
S10A2_HUMAN [view interactions] Low throughput no no
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
HS71B_HUMAN [view entry] [view interactions] Low throughput yes yes
HS71A_HUMAN [view entry] [view interactions] Low throughput yes yes
TBA1A_HUMAN [view entry] [view interactions] Low throughput yes yes
TBB5_HUMAN [view interactions] Low throughput no yes
CSK2B_HUMAN [view entry] [view interactions] High throughput yes yes
PLK1_HUMAN [view interactions] High throughput no yes
AHSA1_HUMAN [view entry] [view interactions] High throughput yes yes
CDC37_HUMAN [view interactions] High throughput no yes
TEBP_HUMAN [view interactions] High throughput no yes
GPAM1_HUMAN [view interactions] High throughput no yes
AKIR2_HUMAN [view interactions] High throughput no no
FIBB_HUMAN [view entry] [view interactions] High throughput yes no
AMTN_HUMAN [view interactions] High throughput no no
TMA16_HUMAN [view interactions] High throughput no yes
DCUP_HUMAN [view interactions] High throughput no no
FGF9_HUMAN [view interactions] High throughput no no
SH2D3_HUMAN [view interactions] High throughput no no
SUZ12_HUMAN [view interactions] High throughput no no
VCAM1_HUMAN [view interactions] High throughput no no
FINC_HUMAN [view interactions] High throughput no yes
MIC60_HUMAN [view entry] [view interactions] High throughput yes yes
HAP1_HUMAN [view entry] [view interactions] High throughput yes yes
KAT7_HUMAN [view interactions] High throughput no yes
TBA1B_HUMAN [view entry] [view interactions] High throughput yes yes
TBB4B_HUMAN [view interactions] High throughput no yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
S10AA_HUMAN [view interactions] High throughput no no
CFTR_HUMAN [view interactions] High throughput no no
IQCB1_HUMAN [view interactions] High throughput no no
TRI27_HUMAN [view interactions] High throughput no yes
SMUF2_HUMAN [view interactions] High throughput no yes
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
MCR_HUMAN [view entry] [view interactions] High throughput yes yes
ANDR_HUMAN [view interactions] High throughput no no
PLCB1_HUMAN [view entry] [view interactions] High throughput yes yes
PCBP4_HUMAN [view interactions] High throughput no no
UNK_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
AEN_HUMAN [view interactions] High throughput no no
CCD83_HUMAN [view interactions] High throughput no no
YAP1_HUMAN [view interactions] High throughput no yes
REST_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
TFE3_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
GSX1_HUMAN [view interactions] High throughput no no
RL29_HUMAN [view entry] [view interactions] High throughput yes yes
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
HXC5_HUMAN [view interactions] High throughput no no
ADA29_HUMAN [view interactions] High throughput no no
CCD71_HUMAN [view interactions] High throughput no no
SPB1_HUMAN [view interactions] High throughput no yes
ZIC2_HUMAN [view interactions] High throughput no no
ZRAN1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
FES_HUMAN [view entry] [view interactions] High throughput yes no
HSF1_HUMAN [view interactions] High throughput no yes
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
LNX1_HUMAN [view entry] [view interactions] High throughput yes yes
FBX25_HUMAN [view interactions] High throughput no no
HPRT_HUMAN [view interactions] High throughput no yes
GSH1_HUMAN [view interactions] High throughput no yes
SERC_HUMAN [view interactions] High throughput no yes
KPYM_HUMAN [view interactions] High throughput no yes
DNJB1_HUMAN [view entry] [view interactions] High throughput yes yes
OAT_HUMAN [view interactions] High throughput no yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
PSD12_HUMAN [view interactions] High throughput no yes
SF01_HUMAN [view interactions] High throughput no yes
ELAV2_HUMAN [view interactions] High throughput no yes
SGTA_HUMAN [view interactions] High throughput no yes
PSMD8_HUMAN [view interactions] High throughput no yes
ADT1_HUMAN [view entry] [view interactions] High throughput yes yes
UNG_HUMAN [view interactions] High throughput no yes
STXB1_HUMAN [view entry] [view interactions] High throughput yes yes
MOB2_HUMAN [view interactions] High throughput no no
M21D2_HUMAN [view interactions] High throughput no yes
GNPI2_HUMAN [view interactions] High throughput no yes
ILKAP_HUMAN [view interactions] High throughput no yes
DC1I2_HUMAN [view entry] [view interactions] High throughput yes yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no
CACO2_HUMAN [view interactions] High throughput no yes
STING_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no