Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

AVPI1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in AVPI1_HUMAN
GO:0046872 metal ion binding 57.1429 4 no
GO:0003723 RNA binding 28.5714 4 no
GO:0031267 small GTPase binding 28.5714 5 no
GO:0051020 GTPase binding 28.5714 4 no
GO:0001664 G protein-coupled receptor binding 28.5714 4 no
GO:0046914 transition metal ion binding 28.5714 5 no
GO:0000287 magnesium ion binding 28.5714 5 no
GO:0004674 protein serine/threonine kinase activity 28.5714 4 no
GO:0004679 AMP-activated protein kinase activity 28.5714 5 no
GO:0004690 cyclic nucleotide-dependent protein kinase activity 28.5714 5 no
GO:0004691 cAMP-dependent protein kinase activity 28.5714 6 no
GO:0004712 protein serine/threonine/tyrosine kinase activity 28.5714 4 no
GO:0005524 ATP binding 28.5714 5 no
GO:0016301 kinase activity 28.5714 4 no
GO:0016773 phosphotransferase activity, alcohol group as acceptor 28.5714 4 no
GO:0017076 purine nucleotide binding 28.5714 4 no
GO:0030554 adenyl nucleotide binding 28.5714 5 no
GO:0031625 ubiquitin protein ligase binding 28.5714 5 no
GO:0032555 purine ribonucleotide binding 28.5714 4 no
GO:0032559 adenyl ribonucleotide binding 28.5714 5 no
GO:0035639 purine ribonucleoside triphosphate binding 28.5714 4 no
GO:0044389 ubiquitin-like protein ligase binding 28.5714 4 no
GO:0106310 protein serine kinase activity 28.5714 4 no
GO:0019900 kinase binding 28.5714 4 no
GO:0019901 protein kinase binding 28.5714 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in AVPI1_HUMAN
GO:0060341 regulation of cellular localization 71.4286 4 no
GO:0070201 regulation of establishment of protein localization 71.4286 6 no
GO:0080090 regulation of primary metabolic process 71.4286 4 no
GO:0010646 regulation of cell communication 71.4286 4 yes
GO:0048522 positive regulation of cellular process 71.4286 4 yes
GO:0032880 regulation of protein localization 71.4286 5 no
GO:0048523 negative regulation of cellular process 71.4286 4 no
GO:0051049 regulation of transport 71.4286 4 no
GO:0051171 regulation of nitrogen compound metabolic process 71.4286 4 no
GO:0051223 regulation of protein transport 71.4286 5 no
GO:0051246 regulation of protein metabolic process 71.4286 5 no
GO:0060255 regulation of macromolecule metabolic process 71.4286 4 no
GO:0030162 regulation of proteolysis 57.1429 6 no
GO:0051128 regulation of cellular component organization 57.1429 4 no
GO:0006468 protein phosphorylation 57.1429 5 no
GO:0006796 phosphate-containing compound metabolic process 57.1429 4 no
GO:0010648 negative regulation of cell communication 57.1429 5 no
GO:0016310 phosphorylation 57.1429 5 no
GO:0023057 negative regulation of signaling 57.1429 4 no
GO:0036211 protein modification process 57.1429 4 no
GO:0043412 macromolecule modification 57.1429 4 no
GO:0009966 regulation of signal transduction 57.1429 4 yes
GO:0008104 protein localization 57.1429 4 no
GO:0031323 regulation of cellular metabolic process 57.1429 4 no
GO:0051050 positive regulation of transport 57.1429 4 no
GO:0051726 regulation of cell cycle 57.1429 4 no
GO:0071310 cellular response to organic substance 42.8571 4 no
GO:0071417 cellular response to organonitrogen compound 42.8571 4 no
GO:0071702 organic substance transport 42.8571 4 no
GO:0071705 nitrogen compound transport 42.8571 4 no
GO:1901699 cellular response to nitrogen compound 42.8571 4 no
GO:1901701 cellular response to oxygen-containing compound 42.8571 4 no
GO:1903829 positive regulation of protein localization 42.8571 5 no
GO:1904951 positive regulation of establishment of protein localization 42.8571 6 no
GO:0009894 regulation of catabolic process 42.8571 4 no
GO:0031329 regulation of cellular catabolic process 42.8571 5 no
GO:0042176 regulation of protein catabolic process 42.8571 5 no
GO:0009968 negative regulation of signal transduction 42.8571 5 no
GO:0010468 regulation of gene expression 42.8571 5 no
GO:0022607 cellular component assembly 42.8571 4 no
GO:0043933 protein-containing complex organization 42.8571 4 no
GO:0048585 negative regulation of response to stimulus 42.8571 4 no
GO:0048878 chemical homeostasis 42.8571 4 no
GO:0050804 modulation of chemical synaptic transmission 42.8571 5 no
GO:0065003 protein-containing complex assembly 42.8571 5 no
GO:0090304 nucleic acid metabolic process 42.8571 4 no
GO:0099177 regulation of trans-synaptic signaling 42.8571 4 no
GO:0006886 intracellular protein transport 42.8571 4 no
GO:0010243 response to organonitrogen compound 42.8571 4 no
GO:0015031 protein transport 42.8571 4 no
GO:0032386 regulation of intracellular transport 42.8571 5 no
GO:0033157 regulation of intracellular protein transport 42.8571 6 no
GO:0033365 protein localization to organelle 42.8571 5 no
GO:0046822 regulation of nucleocytoplasmic transport 42.8571 6 no
GO:0051222 positive regulation of protein transport 42.8571 5 no
GO:0071900 regulation of protein serine/threonine kinase activity 28.5714 7 no
GO:0090316 positive regulation of intracellular protein transport 28.5714 6 no
GO:1900180 regulation of protein localization to nucleus 28.5714 6 no
GO:0010564 regulation of cell cycle process 28.5714 5 no
GO:0046825 regulation of protein export from nucleus 28.5714 7 no
GO:0061136 regulation of proteasomal protein catabolic process 28.5714 6 no
GO:1903050 regulation of proteolysis involved in protein catabolic process 28.5714 7 no
GO:0002090 regulation of receptor internalization 28.5714 7 no
GO:0002092 positive regulation of receptor internalization 28.5714 7 no
GO:0006396 RNA processing 28.5714 6 no
GO:0006397 mRNA processing 28.5714 7 no
GO:0006873 cellular ion homeostasis 28.5714 4 no
GO:0006874 cellular calcium ion homeostasis 28.5714 7 no
GO:0006875 cellular metal ion homeostasis 28.5714 6 no
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 28.5714 4 no
GO:0010639 negative regulation of organelle organization 28.5714 6 no
GO:0014070 response to organic cyclic compound 28.5714 4 no
GO:0016070 RNA metabolic process 28.5714 5 no
GO:0016071 mRNA metabolic process 28.5714 6 no
GO:0016192 vesicle-mediated transport 28.5714 4 no
GO:0019722 calcium-mediated signaling 28.5714 5 no
GO:0019932 second-messenger-mediated signaling 28.5714 4 no
GO:0021782 glial cell development 28.5714 4 no
GO:0022898 regulation of transmembrane transporter activity 28.5714 4 no
GO:0030003 cellular cation homeostasis 28.5714 5 no
GO:0030030 cell projection organization 28.5714 4 no
GO:0030100 regulation of endocytosis 28.5714 5 no
GO:0032412 regulation of ion transmembrane transporter activity 28.5714 5 no
GO:0033043 regulation of organelle organization 28.5714 5 no
GO:0034762 regulation of transmembrane transport 28.5714 4 no
GO:0034765 regulation of ion transmembrane transport 28.5714 5 no
GO:0043269 regulation of ion transport 28.5714 5 no
GO:0043393 regulation of protein binding 28.5714 4 no
GO:0044057 regulation of system process 28.5714 4 no
GO:0044087 regulation of cellular component biogenesis 28.5714 4 no
GO:0045595 regulation of cell differentiation 28.5714 4 no
GO:0045807 positive regulation of endocytosis 28.5714 5 no
GO:0048259 regulation of receptor-mediated endocytosis 28.5714 6 no
GO:0048260 positive regulation of receptor-mediated endocytosis 28.5714 6 no
GO:0050801 ion homeostasis 28.5714 5 no
GO:0051129 negative regulation of cellular component organization 28.5714 5 no
GO:0051130 positive regulation of cellular component organization 28.5714 5 no
GO:0055065 metal ion homeostasis 28.5714 7 no
GO:0055074 calcium ion homeostasis 28.5714 8 no
GO:0055080 cation homeostasis 28.5714 6 no
GO:0060627 regulation of vesicle-mediated transport 28.5714 4 no
GO:0071407 cellular response to organic cyclic compound 28.5714 5 no
GO:0071867 response to monoamine 28.5714 5 no
GO:0071868 cellular response to monoamine stimulus 28.5714 5 no
GO:0071869 response to catecholamine 28.5714 4 no
GO:0071870 cellular response to catecholamine stimulus 28.5714 5 no
GO:0072503 cellular divalent inorganic cation homeostasis 28.5714 6 no
GO:0072507 divalent inorganic cation homeostasis 28.5714 7 no
GO:0098771 inorganic ion homeostasis 28.5714 6 no
GO:0106027 neuron projection organization 28.5714 6 no
GO:0120036 plasma membrane bounded cell projection organization 28.5714 5 no
GO:1901888 regulation of cell junction assembly 28.5714 5 no
GO:1902903 regulation of supramolecular fiber organization 28.5714 5 no
GO:1903522 regulation of blood circulation 28.5714 5 no
GO:1904062 regulation of cation transmembrane transport 28.5714 6 no
GO:2001257 regulation of cation channel activity 28.5714 6 no
GO:0001843 neural tube closure 28.5714 5 no
GO:0003091 renal water homeostasis 28.5714 4 no
GO:0008589 regulation of smoothened signaling pathway 28.5714 5 no
GO:0010737 protein kinase A signaling 28.5714 4 no
GO:0030104 water homeostasis 28.5714 5 no
GO:0034380 high-density lipoprotein particle assembly 28.5714 4 no
GO:0045879 negative regulation of smoothened signaling pathway 28.5714 6 no
GO:0060606 tube closure 28.5714 4 no
GO:0065005 protein-lipid complex assembly 28.5714 6 no
GO:0070613 regulation of protein processing 28.5714 7 no
GO:0071825 protein-lipid complex subunit organization 28.5714 5 no
GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 28.5714 6 no
GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 28.5714 7 no
GO:1903317 regulation of protein maturation 28.5714 6 no
GO:0009967 positive regulation of signal transduction 28.5714 5 yes
GO:0010647 positive regulation of cell communication 28.5714 5 yes
GO:0023056 positive regulation of signaling 28.5714 4 yes
GO:0043408 regulation of MAPK cascade 28.5714 6 yes
GO:0043410 positive regulation of MAPK cascade 28.5714 7 yes
GO:0048584 positive regulation of response to stimulus 28.5714 4 yes
GO:1902531 regulation of intracellular signal transduction 28.5714 5 yes
GO:1902533 positive regulation of intracellular signal transduction 28.5714 6 yes
GO:0001932 regulation of protein phosphorylation 28.5714 7 no
GO:0006913 nucleocytoplasmic transport 28.5714 5 no
GO:0009892 negative regulation of metabolic process 28.5714 4 no
GO:0010605 negative regulation of macromolecule metabolic process 28.5714 5 no
GO:0019220 regulation of phosphate metabolic process 28.5714 6 no
GO:0031324 negative regulation of cellular metabolic process 28.5714 5 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0032388 positive regulation of intracellular transport 28.5714 5 no
GO:0034504 protein localization to nucleus 28.5714 6 no
GO:0042325 regulation of phosphorylation 28.5714 7 no
GO:0043549 regulation of kinase activity 28.5714 5 no
GO:0045859 regulation of protein kinase activity 28.5714 6 no
GO:0046824 positive regulation of nucleocytoplasmic transport 28.5714 6 no
GO:0051169 nuclear transport 28.5714 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 28.5714 5 no
GO:0051174 regulation of phosphorus metabolic process 28.5714 5 no
GO:0051338 regulation of transferase activity 28.5714 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
MDFI_HUMAN [view interactions] High throughput no no
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
K1C40_HUMAN [view interactions] High throughput no no
KR109_HUMAN [view interactions] High throughput no no
KR107_HUMAN [view interactions] High throughput no no
KR122_HUMAN [view interactions] High throughput no no
KR106_HUMAN [view interactions] High throughput no no
GG6L9_HUMAN [view interactions] High throughput no no
K1H1_HUMAN [view interactions] High throughput no no
KRA42_HUMAN [view interactions] High throughput no no
CRTP1_HUMAN [view interactions] High throughput no yes
KR108_HUMAN [view interactions] High throughput no no
ENKD1_HUMAN [view interactions] High throughput no yes
MKRN3_HUMAN [view interactions] High throughput no yes
CA109_HUMAN [view interactions] High throughput no yes
SCNM1_HUMAN [view interactions] High throughput no no
RIPP1_HUMAN [view interactions] High throughput no no
DGC6L_HUMAN [view interactions] High throughput no no
KAPCA_HUMAN [view entry] [view interactions] High throughput yes yes
KAPCB_HUMAN [view entry] [view interactions] High throughput yes yes
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
LONF1_HUMAN [view interactions] High throughput no yes
PP16A_HUMAN [view interactions] High throughput no no
AAPK2_HUMAN [view interactions] High throughput no yes
RPAC1_HUMAN [view interactions] High throughput no no
EMD_HUMAN [view interactions] High throughput no yes
RIPP2_HUMAN [view interactions] High throughput no no
CDA7L_HUMAN [view interactions] High throughput no yes
PHF1_HUMAN [view interactions] High throughput no yes
CABP2_HUMAN [view interactions] High throughput no no
KR101_HUMAN [view interactions] High throughput no no
KR103_HUMAN [view interactions] High throughput no no
LMO3_HUMAN [view interactions] High throughput no no
PIP30_HUMAN [view interactions] High throughput no yes
PSMG4_HUMAN [view interactions] High throughput no yes
G3PT_HUMAN [view interactions] High throughput no no
MACIR_HUMAN [view interactions] High throughput no no
U119B_HUMAN [view interactions] High throughput no yes
PSMG3_HUMAN [view interactions] High throughput no yes
RNBP6_HUMAN [view interactions] High throughput no yes
GGPPS_HUMAN [view interactions] High throughput no yes
U119A_HUMAN [view interactions] High throughput no no
IPO5_HUMAN [view entry] [view interactions] High throughput yes yes
PSME3_HUMAN [view interactions] High throughput no yes
NEMO_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes