HPLN2_HUMAN
Evidence for PS localization
Functions
Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid . [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
No data found.
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in HPLN2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 75.0000 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 50.0000 | 4 | yes |
| GO:0045597 | positive regulation of cell differentiation | 50.0000 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 50.0000 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 50.0000 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 50.0000 | 5 | no |
| GO:0010646 | regulation of cell communication | 50.0000 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 50.0000 | 5 | no |
| GO:0023057 | negative regulation of signaling | 50.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 50.0000 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KRA24_HUMAN | [view interactions] | High throughput | no | no |
| TRI27_HUMAN | [view interactions] | High throughput | no | yes |
| NT2NC_HUMAN | [view interactions] | High throughput | no | no |
| P20D2_HUMAN | [view interactions] | High throughput | no | yes |
| KR108_HUMAN | [view interactions] | High throughput | no | no |
| KRT35_HUMAN | [view interactions] | High throughput | no | no |
| K1C15_HUMAN | [view interactions] | High throughput | no | no |
| TRI23_HUMAN | [view interactions] | High throughput | no | yes |
| MDFI_HUMAN | [view interactions] | High throughput | no | no |
| KRA63_HUMAN | [view interactions] | High throughput | no | no |
| K1C40_HUMAN | [view interactions] | High throughput | no | no |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| PNMA1_HUMAN | [view interactions] | High throughput | no | yes |
| PNMA2_HUMAN | [view interactions] | High throughput | no | yes |
| K1C27_HUMAN | [view interactions] | High throughput | no | no |
| GG6L9_HUMAN | [view interactions] | High throughput | no | no |
| KRT34_HUMAN | [view interactions] | High throughput | no | no |
| CC125_HUMAN | [view interactions] | High throughput | no | yes |
| KRT37_HUMAN | [view interactions] | High throughput | no | no |
| EXOS8_HUMAN | [view interactions] | High throughput | no | yes |
| PPIP1_HUMAN | [view interactions] | High throughput | no | no |
| K1H1_HUMAN | [view interactions] | High throughput | no | no |
| FHL5_HUMAN | [view interactions] | High throughput | no | no |
| KRA62_HUMAN | [view interactions] | High throughput | no | no |
| KRA92_HUMAN | [view interactions] | High throughput | no | no |
| KR195_HUMAN | [view interactions] | High throughput | no | no |
| PFD5_HUMAN | [view interactions] | High throughput | no | yes |
| KT33B_HUMAN | [view interactions] | High throughput | no | no |
| FHL3_HUMAN | [view interactions] | High throughput | no | no |
| KRT85_HUMAN | [view interactions] | High throughput | no | no |
| VWC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZMY12_HUMAN | [view interactions] | High throughput | no | no |
| MS18B_HUMAN | [view interactions] | High throughput | no | no |
| ZN438_HUMAN | [view interactions] | High throughput | no | no |
| PP16B_HUMAN | [view interactions] | High throughput | no | yes |
| ZN655_HUMAN | [view interactions] | High throughput | no | yes |
| CIDEB_HUMAN | [view interactions] | High throughput | no | yes |
| FND3B_HUMAN | [view interactions] | High throughput | no | no |
| TRIM1_HUMAN | [view interactions] | High throughput | no | no |
| MTUS2_HUMAN | [view interactions] | High throughput | no | yes |
| SRB4D_HUMAN | [view interactions] | High throughput | no | no |
| SEC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BANP_HUMAN | [view interactions] | High throughput | no | yes |
| ASB13_HUMAN | [view interactions] | High throughput | no | yes |
| GRIN2_HUMAN | [view interactions] | High throughput | no | yes |
| NT2NA_HUMAN | [view interactions] | High throughput | no | no |