Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

HNRH2_HUMAN

This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG). [View more on UniProt]

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No data found.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in HNRH2_HUMAN
GO:0003723 RNA binding 41.0959 4 yes
GO:0044389 ubiquitin-like protein ligase binding 21.9178 4 no
GO:0000166 nucleotide binding 21.9178 4 no
GO:0043168 anion binding 21.9178 4 no
GO:0017076 purine nucleotide binding 20.5479 5 no
GO:0019900 kinase binding 20.5479 4 no
GO:0019901 protein kinase binding 20.5479 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in HNRH2_HUMAN
GO:0060255 regulation of macromolecule metabolic process 68.4932 4 yes
GO:0031323 regulation of cellular metabolic process 64.3836 4 yes
GO:0080090 regulation of primary metabolic process 63.0137 4 yes
GO:0009889 regulation of biosynthetic process 60.2740 4 yes
GO:0010468 regulation of gene expression 58.9041 6 yes
GO:0010556 regulation of macromolecule biosynthetic process 58.9041 5 yes
GO:0031326 regulation of cellular biosynthetic process 58.9041 5 yes
GO:0048522 positive regulation of cellular process 58.9041 4 no
GO:0048523 negative regulation of cellular process 53.4247 4 no
GO:0009893 positive regulation of metabolic process 52.0548 4 no
GO:0010604 positive regulation of macromolecule metabolic process 49.3151 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 47.9452 5 yes
GO:0010646 regulation of cell communication 46.5753 4 no
GO:0009892 negative regulation of metabolic process 46.5753 4 no
GO:0010605 negative regulation of macromolecule metabolic process 46.5753 5 no
GO:0051252 regulation of RNA metabolic process 45.2055 5 yes
GO:0051128 regulation of cellular component organization 45.2055 4 no
GO:0009966 regulation of signal transduction 43.8356 4 no
GO:0031324 negative regulation of cellular metabolic process 43.8356 5 no
GO:0031325 positive regulation of cellular metabolic process 41.0959 5 no
GO:0009890 negative regulation of biosynthetic process 39.7260 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 39.7260 6 no
GO:0031327 negative regulation of cellular biosynthetic process 39.7260 6 no
GO:0051246 regulation of protein metabolic process 39.7260 5 no
GO:0006996 organelle organization 38.3562 4 no
GO:0009891 positive regulation of biosynthetic process 36.9863 5 no
GO:0022607 cellular component assembly 35.6164 4 no
GO:0043412 macromolecule modification 34.2466 4 no
GO:0031328 positive regulation of cellular biosynthetic process 34.2466 6 no
GO:0008104 protein localization 34.2466 4 no
GO:0009894 regulation of catabolic process 34.2466 4 no
GO:0036211 protein modification process 32.8767 4 no
GO:0006355 regulation of DNA-templated transcription 32.8767 7 no
GO:0010557 positive regulation of macromolecule biosynthetic process 32.8767 6 no
GO:2001141 regulation of RNA biosynthetic process 32.8767 6 no
GO:1902531 regulation of intracellular signal transduction 32.8767 5 no
GO:0051247 positive regulation of protein metabolic process 32.8767 6 no
GO:0043933 protein-containing complex organization 30.1370 4 no
GO:0043067 regulation of programmed cell death 30.1370 4 no
GO:0090304 nucleic acid metabolic process 28.7671 4 no
GO:0042981 regulation of apoptotic process 28.7671 5 no
GO:0010629 negative regulation of gene expression 28.7671 7 no
GO:0071702 organic substance transport 27.3973 4 no
GO:0071705 nitrogen compound transport 27.3973 4 no
GO:0010648 negative regulation of cell communication 26.0274 5 no
GO:0023057 negative regulation of signaling 26.0274 4 no
GO:0048585 negative regulation of response to stimulus 26.0274 4 no
GO:0010628 positive regulation of gene expression 26.0274 7 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 26.0274 5 no
GO:0006357 regulation of transcription by RNA polymerase II 24.6575 8 no
GO:0009968 negative regulation of signal transduction 24.6575 5 no
GO:0051253 negative regulation of RNA metabolic process 24.6575 6 no
GO:0048584 positive regulation of response to stimulus 24.6575 4 no
GO:0031399 regulation of protein modification process 24.6575 6 no
GO:0016070 RNA metabolic process 23.2877 5 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 23.2877 5 no
GO:0010647 positive regulation of cell communication 23.2877 5 no
GO:0023056 positive regulation of signaling 23.2877 4 no
GO:0060341 regulation of cellular localization 21.9178 4 no
GO:0006508 proteolysis 21.9178 4 no
GO:0009057 macromolecule catabolic process 21.9178 4 no
GO:0044087 regulation of cellular component biogenesis 21.9178 4 no
GO:0080134 regulation of response to stress 21.9178 4 no
GO:0051248 negative regulation of protein metabolic process 21.9178 6 no
GO:0032880 regulation of protein localization 20.5479 5 no
GO:0051130 positive regulation of cellular component organization 20.5479 5 no
GO:0065003 protein-containing complex assembly 20.5479 5 no
GO:0033043 regulation of organelle organization 20.5479 5 no
GO:0030162 regulation of proteolysis 20.5479 6 no
GO:0009967 positive regulation of signal transduction 20.5479 5 no
GO:0019220 regulation of phosphate metabolic process 20.5479 6 no
GO:0031401 positive regulation of protein modification process 20.5479 7 no
GO:0051174 regulation of phosphorus metabolic process 20.5479 5 no
GO:0043484 regulation of RNA splicing 15.0685 6 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
GRAB_HUMAN [view interactions] Low throughput no no
HNRPF_HUMAN [view interactions] Low throughput no yes
TNPO1_HUMAN [view entry] [view interactions] Low throughput yes yes
SMN_HUMAN [view interactions] Low throughput no yes
PLST_HUMAN [view interactions] Low throughput no yes
MBNL1_HUMAN [view interactions] Low throughput no yes
ARG39_HUMAN [view interactions] High throughput no yes
NAGK_HUMAN [view interactions] High throughput no no
MGME1_HUMAN [view interactions] High throughput no yes
COPRS_HUMAN [view interactions] High throughput no yes
SUV3_HUMAN [view interactions] High throughput no yes
BACD3_HUMAN [view interactions] High throughput no yes
SPRTN_HUMAN [view interactions] High throughput no yes
UBP11_HUMAN [view interactions] High throughput no yes
MECP2_HUMAN [view interactions] High throughput no yes
SLN11_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
SIR6_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
CLU_HUMAN [view interactions] High throughput no yes
SOX2_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
ICLN_HUMAN [view interactions] High throughput no yes
INP5E_HUMAN [view interactions] High throughput no yes
RBM14_HUMAN [view interactions] High throughput no yes
TRI31_HUMAN [view interactions] High throughput no no
ANM1_HUMAN [view interactions] High throughput no yes
AURKA_HUMAN [view entry] [view interactions] High throughput yes no
MYCN_HUMAN [view interactions] High throughput no no
PLD2_HUMAN [view interactions] High throughput no yes
PLD3_HUMAN [view entry] [view interactions] High throughput yes yes
PLD6_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
AIMP2_HUMAN [view interactions] High throughput no yes
RNF43_HUMAN [view interactions] High throughput no yes
DBLOH_HUMAN [view interactions] High throughput no no
LATS1_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
ANDR_HUMAN [view interactions] High throughput no no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
GATA4_HUMAN [view interactions] High throughput no no
RUFY1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
UBP48_HUMAN [view interactions] High throughput no yes
TET5C_HUMAN [view interactions] High throughput no yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
KAT6A_HUMAN [view interactions] High throughput no yes
RECQ1_HUMAN [view interactions] High throughput no yes
MERL_HUMAN [view interactions] High throughput no yes
OTUD4_HUMAN [view interactions] High throughput no yes
SUMO2_HUMAN [view entry] [view interactions] High throughput yes yes
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
RU1C_HUMAN [view interactions] High throughput no yes
HNRDL_HUMAN [view interactions] High throughput no yes
RBM10_HUMAN [view interactions] High throughput no yes
MAX_HUMAN [view interactions] High throughput no yes
SF01_HUMAN [view interactions] High throughput no yes
SERPH_HUMAN [view interactions] High throughput no no
RBM39_HUMAN [view interactions] High throughput no yes
CIRBP_HUMAN [view interactions] High throughput no no
ILF3_HUMAN [view interactions] High throughput no yes
CNN2_HUMAN [view interactions] High throughput no no
ROA0_HUMAN [view interactions] High throughput no yes
CS025_HUMAN [view interactions] High throughput no no
PRP8_HUMAN [view interactions] High throughput no yes
CLIC4_HUMAN [view interactions] High throughput no no
PRP31_HUMAN [view interactions] High throughput no yes
CRKL_HUMAN [view entry] [view interactions] High throughput yes yes
PQBP1_HUMAN [view interactions] High throughput no yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
WDR83_HUMAN [view interactions] High throughput no yes
GMFB_HUMAN [view interactions] High throughput no yes
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
HIBCH_HUMAN [view entry] [view interactions] High throughput yes yes
HNRL1_HUMAN [view interactions] High throughput no yes
RA1L2_HUMAN [view interactions] High throughput no no
RBM4_HUMAN [view interactions] High throughput no yes
SYIM_HUMAN [view entry] [view interactions] High throughput yes yes
HNRH2_HUMAN [view entry] [view interactions] High throughput yes yes
INO1_HUMAN [view interactions] High throughput no no
RACK1_HUMAN [view interactions] High throughput no yes
LGMN_HUMAN [view interactions] High throughput no yes
QKI_HUMAN [view interactions] High throughput no no
MCM3_HUMAN [view interactions] High throughput no no
RFOX2_HUMAN [view interactions] High throughput no yes
SYYC_HUMAN [view interactions] High throughput no yes
ANM6_HUMAN [view interactions] High throughput no yes
PDCD6_HUMAN [view interactions] High throughput no no
AGO1_HUMAN [view interactions] High throughput no no
ERO1A_HUMAN [view interactions] High throughput no yes
ARRB2_HUMAN [view entry] [view interactions] High throughput yes no
PARVA_HUMAN [view interactions] High throughput no yes
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
THYN1_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
NINL_HUMAN [view interactions] High throughput no yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
ATX1_HUMAN [view interactions] High throughput no yes
GBRL1_HUMAN [view interactions] High throughput no yes
OPTN_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view entry] [view interactions] High throughput yes no
PER2_HUMAN [view interactions] High throughput no yes
IQCB1_HUMAN [view interactions] High throughput no no
STING_HUMAN [view interactions] High throughput no yes
IF4A3_HUMAN [view entry] [view interactions] High throughput yes yes
UBP7_HUMAN [view interactions] High throughput no yes
MGN_HUMAN [view interactions] High throughput no yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
NANP8_HUMAN [view interactions] High throughput no no
RED1_HUMAN [view interactions] High throughput no no
NANOG_HUMAN [view interactions] High throughput no no
DDA1_HUMAN [view interactions] High throughput no yes
MATR3_HUMAN [view interactions] High throughput no yes
PLOD2_HUMAN [view interactions] High throughput no yes
TIRR_HUMAN [view interactions] High throughput no no
P5CR1_HUMAN [view entry] [view interactions] High throughput yes yes
PLOD1_HUMAN [view interactions] High throughput no yes
PKN3_HUMAN [view interactions] High throughput no yes
RB12B_HUMAN [view interactions] High throughput no yes
HNRH3_HUMAN [view interactions] High throughput no no
ABC3B_HUMAN [view interactions] High throughput no no
MAK16_HUMAN [view interactions] High throughput no yes
RBMX_HUMAN [view entry] [view interactions] High throughput yes yes
TADBP_HUMAN [view interactions] High throughput no yes
ROA2_HUMAN [view entry] [view interactions] High throughput yes yes
PCP_HUMAN [view interactions] High throughput no yes
LYST_HUMAN [view interactions] High throughput no no
ZSWM6_HUMAN [view interactions] High throughput no no
MOV10_HUMAN [view interactions] High throughput no no
DDX1_HUMAN [view entry] [view interactions] High throughput yes yes
PLOD3_HUMAN [view interactions] High throughput no yes
ROA3_HUMAN [view entry] [view interactions] High throughput yes yes
HNRL2_HUMAN [view interactions] High throughput no yes
HNRPQ_HUMAN [view entry] [view interactions] High throughput yes yes
EPC2_HUMAN [view interactions] High throughput no yes
F120A_HUMAN [view interactions] High throughput no yes
DDX41_HUMAN [view interactions] High throughput no yes
XPO7_HUMAN [view entry] [view interactions] High throughput yes yes
PRD16_HUMAN [view interactions] High throughput no no
MECOM_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
FINC_HUMAN [view interactions] High throughput no yes
ARGL1_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
KCMA1_HUMAN [view entry] [view interactions] High throughput yes no
ROA1_HUMAN [view entry] [view interactions] High throughput yes yes
TTP_HUMAN [view interactions] High throughput no yes
HTRA4_HUMAN [view interactions] High throughput no no
FASTK_HUMAN [view interactions] High throughput no yes
JUN_HUMAN [view interactions] High throughput no yes
ITM2B_HUMAN [view interactions] High throughput no yes
ANS1B_HUMAN [view entry] [view interactions] High throughput yes yes
LN28A_HUMAN [view interactions] High throughput no no
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
RIMS1_HUMAN [view entry] [view interactions] High throughput yes yes
CAC1C_HUMAN [view entry] [view interactions] High throughput yes no
DYR1A_HUMAN [view interactions] High throughput no yes
CP135_HUMAN [view interactions] High throughput no no
ODFP2_HUMAN [view interactions] High throughput no no
TEKT1_HUMAN [view interactions] High throughput no no
MSI2H_HUMAN [view interactions] High throughput no yes
MSI1H_HUMAN [view interactions] High throughput no no
HSF2B_HUMAN [view interactions] High throughput no yes
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
TOB1_HUMAN [view interactions] High throughput no yes
YBOX1_HUMAN [view interactions] High throughput no yes
SRPK2_HUMAN [view entry] [view interactions] High throughput yes yes
ERBB3_HUMAN [view interactions] High throughput no yes
UBS3B_HUMAN [view interactions] High throughput no yes
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
RAB21_HUMAN [view entry] [view interactions] High throughput yes yes
ESR2_HUMAN [view interactions] High throughput no no
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
4ET_HUMAN [view interactions] High throughput no yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
RAD21_HUMAN [view interactions] High throughput no yes
TLE5_HUMAN [view interactions] High throughput no no
CCNK_HUMAN [view interactions] High throughput no yes
TXN4A_HUMAN [view interactions] High throughput no no
PRR3_HUMAN [view interactions] High throughput no no
SUGP1_HUMAN [view interactions] High throughput no yes
COF1_HUMAN [view entry] [view interactions] High throughput yes no
BAG4_HUMAN [view interactions] High throughput no yes
RBM7_HUMAN [view interactions] High throughput no yes
NONO_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
MEPCE_HUMAN [view interactions] High throughput no yes
GPN1_HUMAN [view interactions] High throughput no yes
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC5_HUMAN [view interactions] High throughput no yes
DMRT2_HUMAN [view interactions] High throughput no no
SUMO3_HUMAN [view entry] [view interactions] High throughput yes yes
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
CUL4B_HUMAN [view interactions] High throughput no yes
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
CUL2_HUMAN [view interactions] High throughput no yes
CUL1_HUMAN [view interactions] High throughput no yes
CSN5_HUMAN [view interactions] High throughput no yes
CSN6_HUMAN [view interactions] High throughput no yes
DCNL1_HUMAN [view interactions] High throughput no yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
NEDD8_HUMAN [view entry] [view interactions] High throughput yes yes
FBX6_HUMAN [view interactions] High throughput no yes
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
SMUF1_HUMAN [view interactions] High throughput no yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
ERR2_HUMAN [view interactions] High throughput no no
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
FBW1B_HUMAN [view interactions] High throughput no yes
HNRPD_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPM_HUMAN [view entry] [view interactions] High throughput yes yes
TNK1_HUMAN [view interactions] High throughput no yes
RUSC1_HUMAN [view entry] [view interactions] High throughput yes yes
ZSWM5_HUMAN [view interactions] High throughput no no
QSER1_HUMAN [view interactions] High throughput no no
CRY1_HUMAN [view interactions] High throughput no yes
MCM2_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
WDTC1_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
FOXA1_HUMAN [view interactions] High throughput no no
G3BP1_HUMAN [view interactions] High throughput no yes
BRCA1_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
FBX7_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
MEP50_HUMAN [view interactions] High throughput no yes
TNIP2_HUMAN [view interactions] High throughput no yes
RIOK1_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
PPT1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
DCPS_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
RC3H1_HUMAN [view interactions] High throughput no yes
RC3H2_HUMAN [view interactions] High throughput no yes
PSA3_HUMAN [view interactions] High throughput no no
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
KPCD2_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
UCHL3_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
TRPV1_HUMAN [view entry] [view interactions] High throughput yes no
H4_HUMAN [view interactions] High throughput no yes
PSDE_HUMAN [view entry] [view interactions] High throughput yes yes
RU17_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
TIF1B_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
MAGA3_HUMAN [view interactions] High throughput no no
PINK1_HUMAN [view interactions] High throughput no yes
SCC4_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
AURKB_HUMAN [view interactions] High throughput no yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4C_HUMAN [view interactions] High throughput no yes
ECT2_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
PRC1_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
CEBPA_HUMAN [view interactions] High throughput no yes
CIC_HUMAN [view interactions] High throughput no yes
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
NR4A1_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes
FZR1_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no