Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

HNRH2_HUMAN

This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG). [View more on UniProt]

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Download full PS network for entry.

No data found.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in HNRH2_HUMAN
GO:0003723 RNA binding 45.0000 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in HNRH2_HUMAN
GO:0060255 regulation of macromolecule metabolic process 66.6667 4 yes
GO:0031323 regulation of cellular metabolic process 65.0000 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 65.0000 4 yes
GO:0080090 regulation of primary metabolic process 65.0000 4 yes
GO:0048522 positive regulation of cellular process 61.6667 4 no
GO:0010468 regulation of gene expression 60.0000 5 yes
GO:0048523 negative regulation of cellular process 55.0000 4 no
GO:0009893 positive regulation of metabolic process 55.0000 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 53.3333 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 51.6667 5 no
GO:0051252 regulation of RNA metabolic process 50.0000 5 yes
GO:0009889 regulation of biosynthetic process 46.6667 4 no
GO:0031326 regulation of cellular biosynthetic process 46.6667 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 46.6667 5 no
GO:0010556 regulation of macromolecule biosynthetic process 45.0000 5 no
GO:0031325 positive regulation of cellular metabolic process 45.0000 5 no
GO:0051128 regulation of cellular component organization 43.3333 4 no
GO:0009892 negative regulation of metabolic process 43.3333 4 no
GO:0010605 negative regulation of macromolecule metabolic process 41.6667 5 no
GO:0010646 regulation of cell communication 40.0000 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 38.3333 5 no
GO:0009966 regulation of signal transduction 38.3333 4 no
GO:0031324 negative regulation of cellular metabolic process 38.3333 5 no
GO:0051246 regulation of protein metabolic process 36.6667 5 no
GO:0090304 nucleic acid metabolic process 35.0000 4 no
GO:0006355 regulation of DNA-templated transcription 35.0000 6 no
GO:0043412 macromolecule modification 35.0000 4 no
GO:1903506 regulation of nucleic acid-templated transcription 35.0000 7 no
GO:2001141 regulation of RNA biosynthetic process 35.0000 6 no
GO:0006996 organelle organization 33.3333 4 no
GO:0009891 positive regulation of biosynthetic process 33.3333 5 no
GO:0031328 positive regulation of cellular biosynthetic process 33.3333 6 no
GO:0036211 protein modification process 33.3333 4 no
GO:0010941 regulation of cell death 33.3333 4 no
GO:0051247 positive regulation of protein metabolic process 30.0000 6 no
GO:0071702 organic substance transport 30.0000 4 no
GO:0071705 nitrogen compound transport 30.0000 4 no
GO:0006357 regulation of transcription by RNA polymerase II 30.0000 7 no
GO:0010557 positive regulation of macromolecule biosynthetic process 30.0000 6 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 30.0000 6 no
GO:0022607 cellular component assembly 28.3333 4 no
GO:0016070 RNA metabolic process 28.3333 5 no
GO:0043067 regulation of programmed cell death 28.3333 5 no
GO:0009894 regulation of catabolic process 26.6667 4 no
GO:0010628 positive regulation of gene expression 26.6667 6 no
GO:1902531 regulation of intracellular signal transduction 26.6667 5 no
GO:0008104 protein localization 26.6667 4 no
GO:0010629 negative regulation of gene expression 26.6667 6 no
GO:0042981 regulation of apoptotic process 26.6667 6 no
GO:0031399 regulation of protein modification process 25.0000 6 no
GO:0048585 negative regulation of response to stimulus 23.3333 4 no
GO:0051248 negative regulation of protein metabolic process 23.3333 6 no
GO:0051254 positive regulation of RNA metabolic process 23.3333 6 no
GO:0006508 proteolysis 23.3333 4 no
GO:0009890 negative regulation of biosynthetic process 23.3333 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 23.3333 6 no
GO:0031327 negative regulation of cellular biosynthetic process 23.3333 6 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 21.6667 6 no
GO:0031329 regulation of cellular catabolic process 21.6667 5 no
GO:0080134 regulation of response to stress 21.6667 4 no
GO:0033043 regulation of organelle organization 21.6667 5 no
GO:0006396 RNA processing 21.6667 6 no
GO:0009057 macromolecule catabolic process 21.6667 4 no
GO:0044265 cellular macromolecule catabolic process 21.6667 4 no
GO:0045893 positive regulation of DNA-templated transcription 21.6667 7 no
GO:0051130 positive regulation of cellular component organization 21.6667 5 no
GO:1902680 positive regulation of RNA biosynthetic process 21.6667 7 no
GO:1903508 positive regulation of nucleic acid-templated transcription 21.6667 8 no
GO:0010648 negative regulation of cell communication 21.6667 5 no
GO:0023057 negative regulation of signaling 21.6667 4 no
GO:0043484 regulation of RNA splicing 16.6667 6 yes

Disease

Term Name % Distance from top the of the tree Annotated in HNRH2_HUMAN
DOID:0050686 organ system cancer 3.3333 3 no
DOID:0050539 Charcot-Marie-Tooth disease type 2 3.3333 7 no
DOID:10595 Charcot-Marie-Tooth disease 3.3333 6 no
DOID:440 neuromuscular disease 3.3333 5 no
DOID:574 peripheral nervous system disease 3.3333 3 no
DOID:870 neuropathy 3.3333 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
MBNL1_HUMAN [view interactions] Low throughput no yes
GRAB_HUMAN [view interactions] Low throughput no no
HNRPF_HUMAN [view interactions] Low throughput no yes
PLST_HUMAN [view interactions] Low throughput no yes
SMN_HUMAN [view interactions] Low throughput no yes
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
TOB1_HUMAN [view interactions] High throughput no yes
YBOX1_HUMAN [view interactions] High throughput no yes
SRPK2_HUMAN [view entry] [view interactions] High throughput yes yes
ERBB3_HUMAN [view interactions] High throughput no yes
UBS3B_HUMAN [view interactions] High throughput no yes
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
RAB21_HUMAN [view entry] [view interactions] High throughput yes yes
ESR2_HUMAN [view interactions] High throughput no no
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
RAD21_HUMAN [view interactions] High throughput no yes
TLE5_HUMAN [view interactions] High throughput no no
CCNK_HUMAN [view interactions] High throughput no yes
TXN4A_HUMAN [view interactions] High throughput no no
PRR3_HUMAN [view interactions] High throughput no no
SUGP1_HUMAN [view interactions] High throughput no yes
COF1_HUMAN [view entry] [view interactions] High throughput yes no
BAG4_HUMAN [view interactions] High throughput no yes
RBM7_HUMAN [view interactions] High throughput no yes
NONO_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
MEPCE_HUMAN [view interactions] High throughput no yes
GPN1_HUMAN [view interactions] High throughput no yes
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC5_HUMAN [view interactions] High throughput no yes
DMRT2_HUMAN [view interactions] High throughput no no
SUMO2_HUMAN [view interactions] High throughput no yes
SUMO3_HUMAN [view interactions] High throughput no yes
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
CUL4B_HUMAN [view interactions] High throughput no yes
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
CUL2_HUMAN [view interactions] High throughput no yes
CUL1_HUMAN [view interactions] High throughput no yes
CSN5_HUMAN [view interactions] High throughput no yes
CSN6_HUMAN [view interactions] High throughput no yes
DCNL1_HUMAN [view interactions] High throughput no yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
NEDD8_HUMAN [view interactions] High throughput no yes
FBX6_HUMAN [view interactions] High throughput no yes
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
SMUF1_HUMAN [view interactions] High throughput no yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
ERR2_HUMAN [view interactions] High throughput no no
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
FBW1B_HUMAN [view interactions] High throughput no yes
HNRPD_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPM_HUMAN [view entry] [view interactions] High throughput yes yes
TNK1_HUMAN [view interactions] High throughput no yes
RUSC1_HUMAN [view entry] [view interactions] High throughput yes yes
ZSWM5_HUMAN [view interactions] High throughput no no
QSER1_HUMAN [view interactions] High throughput no yes
CRY1_HUMAN [view interactions] High throughput no yes
MCM2_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
WDTC1_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
FOXA1_HUMAN [view interactions] High throughput no no
G3BP1_HUMAN [view interactions] High throughput no yes
BRCA1_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
FBX7_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
MEP50_HUMAN [view interactions] High throughput no yes
TNIP2_HUMAN [view interactions] High throughput no yes
RIOK1_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
PPT1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
DCPS_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
RC3H1_HUMAN [view interactions] High throughput no yes
RC3H2_HUMAN [view interactions] High throughput no yes
PSA3_HUMAN [view interactions] High throughput no no
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
KPCD2_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
UCHL3_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
TRPV1_HUMAN [view entry] [view interactions] High throughput yes no
H4_HUMAN [view interactions] High throughput no yes
PSDE_HUMAN [view entry] [view interactions] High throughput yes yes
RU17_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
TIF1B_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
MAGA3_HUMAN [view interactions] High throughput no no
PINK1_HUMAN [view interactions] High throughput no yes
SCC4_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
AURKB_HUMAN [view interactions] High throughput no yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4C_HUMAN [view interactions] High throughput no yes
ECT2_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
PRC1_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
CEBPA_HUMAN [view interactions] High throughput no yes
CIC_HUMAN [view interactions] High throughput no yes
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
NR4A1_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes
FZR1_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no
ARG39_HUMAN [view interactions] High throughput no yes
NAGK_HUMAN [view interactions] High throughput no no
MGME1_HUMAN [view interactions] High throughput no yes
COPRS_HUMAN [view interactions] High throughput no yes
SUV3_HUMAN [view interactions] High throughput no yes
BACD3_HUMAN [view interactions] High throughput no yes
SPRTN_HUMAN [view interactions] High throughput no yes
UBP11_HUMAN [view interactions] High throughput no yes
MECP2_HUMAN [view interactions] High throughput no yes
SLN11_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
SIR6_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
CLU_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
ICLN_HUMAN [view interactions] High throughput no yes
INP5E_HUMAN [view interactions] High throughput no yes
RBM14_HUMAN [view interactions] High throughput no yes
OTUD4_HUMAN [view interactions] High throughput no yes
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
HNRDL_HUMAN [view interactions] High throughput no yes
MAX_HUMAN [view interactions] High throughput no yes
SERPH_HUMAN [view interactions] High throughput no no
CIRBP_HUMAN [view interactions] High throughput no no
CNN2_HUMAN [view interactions] High throughput no no
CS025_HUMAN [view interactions] High throughput no no
CLIC4_HUMAN [view interactions] High throughput no no
CRKL_HUMAN [view entry] [view interactions] High throughput yes yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
GMFB_HUMAN [view interactions] High throughput no yes
HIBCH_HUMAN [view entry] [view interactions] High throughput yes yes
RA1L2_HUMAN [view interactions] High throughput no no
SYIM_HUMAN [view entry] [view interactions] High throughput yes yes
INO1_HUMAN [view interactions] High throughput no no
LGMN_HUMAN [view interactions] High throughput no yes
MCM3_HUMAN [view interactions] High throughput no no
SYYC_HUMAN [view interactions] High throughput no yes
PDCD6_HUMAN [view interactions] High throughput no no
NINL_HUMAN [view interactions] High throughput no yes
ATX1_HUMAN [view interactions] High throughput no yes
OPTN_HUMAN [view interactions] High throughput no yes
PER2_HUMAN [view interactions] High throughput no yes
RU1C_HUMAN [view interactions] High throughput no yes
RBM10_HUMAN [view interactions] High throughput no yes
SF01_HUMAN [view interactions] High throughput no yes
RBM39_HUMAN [view interactions] High throughput no yes
ILF3_HUMAN [view interactions] High throughput no yes
ROA0_HUMAN [view interactions] High throughput no yes
PRP8_HUMAN [view interactions] High throughput no yes
PRP31_HUMAN [view interactions] High throughput no yes
PQBP1_HUMAN [view interactions] High throughput no yes
WDR83_HUMAN [view interactions] High throughput no yes
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
HNRL1_HUMAN [view interactions] High throughput no yes
RBM4_HUMAN [view interactions] High throughput no yes
HNRH2_HUMAN [view entry] [view interactions] High throughput yes yes
RACK1_HUMAN [view interactions] High throughput no yes
QKI_HUMAN [view interactions] High throughput no no
RFOX2_HUMAN [view interactions] High throughput no yes
ANM6_HUMAN [view interactions] High throughput no yes
AGO1_HUMAN [view interactions] High throughput no no
ARRB2_HUMAN [view entry] [view interactions] High throughput yes no
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3B_HUMAN [view interactions] High throughput no yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
GBRL1_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view interactions] High throughput no no
IQCB1_HUMAN [view interactions] High throughput no no
MGN_HUMAN [view interactions] High throughput no yes
IF4A3_HUMAN [view entry] [view interactions] High throughput yes yes
NANOG_HUMAN [view interactions] High throughput no no
NANP8_HUMAN [view interactions] High throughput no no
MATR3_HUMAN [view interactions] High throughput no yes
F120A_HUMAN [view interactions] High throughput no yes
EPC2_HUMAN [view interactions] High throughput no yes
HNRPQ_HUMAN [view entry] [view interactions] High throughput yes yes
HNRL2_HUMAN [view interactions] High throughput no yes
ROA3_HUMAN [view entry] [view interactions] High throughput yes yes
PLOD3_HUMAN [view interactions] High throughput no yes
DDX1_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
ZSWM6_HUMAN [view interactions] High throughput no no
LYST_HUMAN [view interactions] High throughput no no
PCP_HUMAN [view interactions] High throughput no yes
ROA2_HUMAN [view entry] [view interactions] High throughput yes yes
TADBP_HUMAN [view interactions] High throughput no yes
RBMX_HUMAN [view entry] [view interactions] High throughput yes yes
MAK16_HUMAN [view interactions] High throughput no yes
ABC3B_HUMAN [view interactions] High throughput no no
HNRH3_HUMAN [view interactions] High throughput no no
RB12B_HUMAN [view interactions] High throughput no yes
PKN3_HUMAN [view interactions] High throughput no yes
PLOD1_HUMAN [view interactions] High throughput no yes
P5CR1_HUMAN [view entry] [view interactions] High throughput yes yes
TIRR_HUMAN [view interactions] High throughput no no
PLOD2_HUMAN [view interactions] High throughput no yes
DDX41_HUMAN [view interactions] High throughput no yes
XPO7_HUMAN [view entry] [view interactions] High throughput yes yes
PRD16_HUMAN [view interactions] High throughput no no
MECOM_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
FINC_HUMAN [view interactions] High throughput no yes
ARGL1_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
KCMA1_HUMAN [view entry] [view interactions] High throughput yes no
ROA1_HUMAN [view entry] [view interactions] High throughput yes yes
TTP_HUMAN [view interactions] High throughput no yes
HTRA4_HUMAN [view interactions] High throughput no no
FASTK_HUMAN [view interactions] High throughput no yes
JUN_HUMAN [view interactions] High throughput no yes
ITM2B_HUMAN [view interactions] High throughput no yes
ANS1B_HUMAN [view entry] [view interactions] High throughput yes yes
MSI2H_HUMAN [view interactions] High throughput no yes
TEKT1_HUMAN [view interactions] High throughput no no
MSI1H_HUMAN [view interactions] High throughput no no
HSF2B_HUMAN [view interactions] High throughput no yes
PTBP1_HUMAN [view interactions] Computational no no
SRSF1_HUMAN [view interactions] Computational no yes
HNRPR_HUMAN [view interactions] Computational no yes
PCBP2_HUMAN [view entry] [view interactions] Computational yes yes
CELF1_HUMAN [view interactions] Computational no yes
PCBP1_HUMAN [view entry] [view interactions] Computational yes yes
HNRPL_HUMAN [view interactions] Computational no yes
HNRPC_HUMAN [view interactions] Computational no yes