Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PKHA6_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

[View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PKHA6_HUMAN
GO:0046872 metal ion binding 30.7692 4 no
GO:0019900 kinase binding 30.7692 4 no
GO:0019901 protein kinase binding 30.7692 5 no
GO:0017076 purine nucleotide binding 30.7692 4 no
GO:0032555 purine ribonucleotide binding 30.7692 4 no
GO:0035639 purine ribonucleoside triphosphate binding 30.7692 4 no
GO:0003723 RNA binding 23.0769 4 no
GO:0045296 cadherin binding 23.0769 4 no
GO:0005524 ATP binding 23.0769 5 no
GO:0030554 adenyl nucleotide binding 23.0769 5 no
GO:0032559 adenyl ribonucleotide binding 23.0769 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in PKHA6_HUMAN
GO:0048522 positive regulation of cellular process 69.2308 4 no
GO:0048523 negative regulation of cellular process 69.2308 4 no
GO:0051171 regulation of nitrogen compound metabolic process 69.2308 4 no
GO:0060255 regulation of macromolecule metabolic process 69.2308 4 no
GO:0080090 regulation of primary metabolic process 69.2308 4 no
GO:0031323 regulation of cellular metabolic process 61.5385 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 53.8462 5 no
GO:0051246 regulation of protein metabolic process 53.8462 5 no
GO:0009893 positive regulation of metabolic process 53.8462 4 no
GO:0010646 regulation of cell communication 53.8462 4 no
GO:0031325 positive regulation of cellular metabolic process 46.1538 5 no
GO:0032880 regulation of protein localization 46.1538 5 no
GO:0051049 regulation of transport 46.1538 4 no
GO:0060341 regulation of cellular localization 46.1538 4 no
GO:0009966 regulation of signal transduction 46.1538 4 no
GO:0010941 regulation of cell death 46.1538 4 no
GO:0042981 regulation of apoptotic process 46.1538 6 no
GO:0043067 regulation of programmed cell death 46.1538 5 no
GO:0010468 regulation of gene expression 46.1538 5 no
GO:0010604 positive regulation of macromolecule metabolic process 46.1538 5 no
GO:0022607 cellular component assembly 38.4615 4 no
GO:0051128 regulation of cellular component organization 38.4615 4 no
GO:0051247 positive regulation of protein metabolic process 38.4615 6 no
GO:0009967 positive regulation of signal transduction 38.4615 5 no
GO:0010647 positive regulation of cell communication 38.4615 5 no
GO:0010942 positive regulation of cell death 38.4615 5 no
GO:0023056 positive regulation of signaling 38.4615 4 no
GO:0048584 positive regulation of response to stimulus 38.4615 4 no
GO:0051093 negative regulation of developmental process 38.4615 4 no
GO:1902531 regulation of intracellular signal transduction 38.4615 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 38.4615 5 no
GO:0051252 regulation of RNA metabolic process 38.4615 5 no
GO:0008104 protein localization 38.4615 4 no
GO:0031326 regulation of cellular biosynthetic process 30.7692 5 no
GO:0031328 positive regulation of cellular biosynthetic process 30.7692 6 no
GO:0051223 regulation of protein transport 30.7692 5 no
GO:0070201 regulation of establishment of protein localization 30.7692 6 no
GO:0071310 cellular response to organic substance 30.7692 4 no
GO:0071407 cellular response to organic cyclic compound 30.7692 5 no
GO:0071417 cellular response to organonitrogen compound 30.7692 4 no
GO:1901699 cellular response to nitrogen compound 30.7692 4 no
GO:1901701 cellular response to oxygen-containing compound 30.7692 4 no
GO:1903506 regulation of nucleic acid-templated transcription 30.7692 7 no
GO:2000145 regulation of cell motility 30.7692 4 no
GO:2001141 regulation of RNA biosynthetic process 30.7692 6 no
GO:0009892 negative regulation of metabolic process 30.7692 4 no
GO:0010605 negative regulation of macromolecule metabolic process 30.7692 5 no
GO:0031324 negative regulation of cellular metabolic process 30.7692 5 no
GO:0031399 regulation of protein modification process 30.7692 6 no
GO:0043085 positive regulation of catalytic activity 30.7692 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 30.7692 5 no
GO:0009968 negative regulation of signal transduction 30.7692 5 no
GO:0010648 negative regulation of cell communication 30.7692 5 no
GO:0023057 negative regulation of signaling 30.7692 4 no
GO:0042127 regulation of cell population proliferation 30.7692 4 no
GO:0043065 positive regulation of apoptotic process 30.7692 7 no
GO:0043066 negative regulation of apoptotic process 30.7692 7 no
GO:0043068 positive regulation of programmed cell death 30.7692 6 no
GO:0043069 negative regulation of programmed cell death 30.7692 6 no
GO:0045595 regulation of cell differentiation 30.7692 4 no
GO:0045596 negative regulation of cell differentiation 30.7692 5 no
GO:0048585 negative regulation of response to stimulus 30.7692 4 no
GO:0051241 negative regulation of multicellular organismal process 30.7692 4 no
GO:0060548 negative regulation of cell death 30.7692 5 no
GO:1902533 positive regulation of intracellular signal transduction 30.7692 6 no
GO:0006355 regulation of DNA-templated transcription 30.7692 6 no
GO:0009889 regulation of biosynthetic process 30.7692 4 no
GO:0009891 positive regulation of biosynthetic process 30.7692 5 no
GO:0010243 response to organonitrogen compound 30.7692 4 no
GO:0010556 regulation of macromolecule biosynthetic process 30.7692 5 no
GO:0014070 response to organic cyclic compound 30.7692 4 no
GO:0030030 cell projection organization 23.0769 4 no
GO:0030334 regulation of cell migration 23.0769 5 no
GO:0031175 neuron projection development 23.0769 6 no
GO:0034329 cell junction assembly 23.0769 5 no
GO:0034330 cell junction organization 23.0769 4 no
GO:0040013 negative regulation of locomotion 23.0769 4 no
GO:0042176 regulation of protein catabolic process 23.0769 5 no
GO:0045216 cell-cell junction organization 23.0769 5 no
GO:0045893 positive regulation of DNA-templated transcription 23.0769 7 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 23.0769 6 no
GO:0048732 gland development 23.0769 4 no
GO:0050804 modulation of chemical synaptic transmission 23.0769 5 no
GO:0051050 positive regulation of transport 23.0769 4 no
GO:0051254 positive regulation of RNA metabolic process 23.0769 6 no
GO:0071680 response to indole-3-methanol 23.0769 5 no
GO:0071681 cellular response to indole-3-methanol 23.0769 5 no
GO:0097305 response to alcohol 23.0769 4 no
GO:0097306 cellular response to alcohol 23.0769 5 no
GO:0099177 regulation of trans-synaptic signaling 23.0769 4 no
GO:0120036 plasma membrane bounded cell projection organization 23.0769 5 no
GO:1902680 positive regulation of RNA biosynthetic process 23.0769 7 no
GO:1903508 positive regulation of nucleic acid-templated transcription 23.0769 8 no
GO:2000146 negative regulation of cell motility 23.0769 5 no
GO:0001932 regulation of protein phosphorylation 23.0769 7 no
GO:0019220 regulation of phosphate metabolic process 23.0769 6 no
GO:0031400 negative regulation of protein modification process 23.0769 7 no
GO:0031401 positive regulation of protein modification process 23.0769 7 no
GO:0042325 regulation of phosphorylation 23.0769 7 no
GO:0051046 regulation of secretion 23.0769 5 no
GO:0051174 regulation of phosphorus metabolic process 23.0769 5 no
GO:0051248 negative regulation of protein metabolic process 23.0769 6 no
GO:0051338 regulation of transferase activity 23.0769 4 no
GO:1903828 negative regulation of protein localization 23.0769 5 no
GO:0010564 regulation of cell cycle process 23.0769 5 no
GO:0030162 regulation of proteolysis 23.0769 6 no
GO:0051726 regulation of cell cycle 23.0769 4 no
GO:0071702 organic substance transport 23.0769 4 no
GO:0071705 nitrogen compound transport 23.0769 4 no
GO:0008285 negative regulation of cell population proliferation 23.0769 5 no
GO:0009890 negative regulation of biosynthetic process 23.0769 5 no
GO:0010721 negative regulation of cell development 23.0769 6 no
GO:0036211 protein modification process 23.0769 4 no
GO:0043412 macromolecule modification 23.0769 4 no
GO:0043523 regulation of neuron apoptotic process 23.0769 6 no
GO:0050865 regulation of cell activation 23.0769 4 no
GO:0051240 positive regulation of multicellular organismal process 23.0769 4 no
GO:0060284 regulation of cell development 23.0769 5 no
GO:1901214 regulation of neuron death 23.0769 5 no
GO:1901215 negative regulation of neuron death 23.0769 6 no
GO:2001233 regulation of apoptotic signaling pathway 23.0769 5 no
GO:0006996 organelle organization 23.0769 4 no
GO:0007010 cytoskeleton organization 23.0769 5 no
GO:0009894 regulation of catabolic process 23.0769 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 23.0769 6 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PEX14_HUMAN [view interactions] High throughput no yes
MBPHL_HUMAN [view interactions] High throughput no no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
HMGA2_HUMAN [view interactions] High throughput no yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
UBE2Z_HUMAN [view interactions] High throughput no yes
PKHA5_HUMAN [view entry] [view interactions] High throughput yes yes
EPHA1_HUMAN [view interactions] High throughput no yes
APOE_HUMAN [view entry] [view interactions] High throughput yes yes
NTRK1_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
MED9_HUMAN [view interactions] High throughput no no
ESR2_HUMAN [view interactions] High throughput no no
TRPV1_HUMAN [view entry] [view interactions] High throughput yes no
PKHA4_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
F16P1_HUMAN [view interactions] High throughput no no
ZMY19_HUMAN [view interactions] High throughput no yes
TCAL9_HUMAN [view interactions] High throughput no yes
KCTD9_HUMAN [view interactions] High throughput no no
PFD1_HUMAN [view interactions] High throughput no yes
ARMC8_HUMAN [view interactions] High throughput no yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
CTNA1_HUMAN [view entry] [view interactions] High throughput yes yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no
PARD3_HUMAN [view interactions] High throughput no yes
GOT1A_HUMAN [view interactions] Computational no no