Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PKHA6_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

[View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PKHA6_HUMAN
GO:0019900 kinase binding 35.7143 4 no
GO:0019901 protein kinase binding 35.7143 5 no
GO:0043169 cation binding 35.7143 4 no
GO:0046872 metal ion binding 35.7143 5 no
GO:0043168 anion binding 35.7143 4 no
GO:0003723 RNA binding 28.5714 4 no
GO:0000166 nucleotide binding 28.5714 4 no
GO:0017076 purine nucleotide binding 28.5714 5 no
GO:0032555 purine ribonucleotide binding 28.5714 4 no
GO:0035639 purine ribonucleoside triphosphate binding 28.5714 4 no
GO:0045296 cadherin binding 21.4286 4 no
GO:0005524 ATP binding 21.4286 5 no
GO:0030554 adenyl nucleotide binding 21.4286 6 no
GO:0032559 adenyl ribonucleotide binding 21.4286 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in PKHA6_HUMAN
GO:0048522 positive regulation of cellular process 71.4286 4 no
GO:0060255 regulation of macromolecule metabolic process 71.4286 4 no
GO:0048523 negative regulation of cellular process 64.2857 4 no
GO:0080090 regulation of primary metabolic process 64.2857 4 no
GO:0009893 positive regulation of metabolic process 57.1429 4 no
GO:0010646 regulation of cell communication 57.1429 4 no
GO:0031323 regulation of cellular metabolic process 57.1429 4 no
GO:0009889 regulation of biosynthetic process 50.0000 4 no
GO:0010468 regulation of gene expression 50.0000 6 no
GO:0010556 regulation of macromolecule biosynthetic process 50.0000 5 no
GO:0010604 positive regulation of macromolecule metabolic process 50.0000 5 no
GO:0031326 regulation of cellular biosynthetic process 50.0000 5 no
GO:0051246 regulation of protein metabolic process 50.0000 5 no
GO:0009966 regulation of signal transduction 50.0000 4 no
GO:0008104 protein localization 42.8571 4 no
GO:0009891 positive regulation of biosynthetic process 42.8571 5 no
GO:0022607 cellular component assembly 42.8571 4 no
GO:0031325 positive regulation of cellular metabolic process 42.8571 5 no
GO:0051128 regulation of cellular component organization 42.8571 4 no
GO:0009967 positive regulation of signal transduction 42.8571 5 no
GO:0010647 positive regulation of cell communication 42.8571 5 no
GO:0023056 positive regulation of signaling 42.8571 4 no
GO:0042981 regulation of apoptotic process 42.8571 5 no
GO:0043067 regulation of programmed cell death 42.8571 4 no
GO:0048584 positive regulation of response to stimulus 42.8571 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 35.7143 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 35.7143 5 no
GO:0031328 positive regulation of cellular biosynthetic process 35.7143 6 no
GO:0032880 regulation of protein localization 35.7143 5 no
GO:0045595 regulation of cell differentiation 35.7143 4 no
GO:0045596 negative regulation of cell differentiation 35.7143 5 no
GO:0051049 regulation of transport 35.7143 4 no
GO:0051093 negative regulation of developmental process 35.7143 4 no
GO:0051241 negative regulation of multicellular organismal process 35.7143 4 no
GO:0051252 regulation of RNA metabolic process 35.7143 5 no
GO:0060284 regulation of cell development 35.7143 5 no
GO:0060341 regulation of cellular localization 35.7143 4 no
GO:0051240 positive regulation of multicellular organismal process 35.7143 4 no
GO:0051247 positive regulation of protein metabolic process 35.7143 6 no
GO:1902531 regulation of intracellular signal transduction 35.7143 5 no
GO:0006355 regulation of DNA-templated transcription 28.5714 7 no
GO:0010243 response to organonitrogen compound 28.5714 4 no
GO:0010721 negative regulation of cell development 28.5714 6 no
GO:0014070 response to organic cyclic compound 28.5714 4 no
GO:0022603 regulation of anatomical structure morphogenesis 28.5714 4 no
GO:0050767 regulation of neurogenesis 28.5714 6 no
GO:0050804 modulation of chemical synaptic transmission 28.5714 5 no
GO:0051960 regulation of nervous system development 28.5714 5 no
GO:0071310 cellular response to organic substance 28.5714 4 no
GO:0071407 cellular response to organic cyclic compound 28.5714 5 no
GO:0071417 cellular response to organonitrogen compound 28.5714 4 no
GO:0099177 regulation of trans-synaptic signaling 28.5714 4 no
GO:1901699 cellular response to nitrogen compound 28.5714 4 no
GO:1901701 cellular response to oxygen-containing compound 28.5714 4 no
GO:2000026 regulation of multicellular organismal development 28.5714 4 no
GO:2000145 regulation of cell motility 28.5714 4 no
GO:2001141 regulation of RNA biosynthetic process 28.5714 6 no
GO:0009892 negative regulation of metabolic process 28.5714 4 no
GO:0009968 negative regulation of signal transduction 28.5714 5 no
GO:0010605 negative regulation of macromolecule metabolic process 28.5714 5 no
GO:0010648 negative regulation of cell communication 28.5714 5 no
GO:0023057 negative regulation of signaling 28.5714 4 no
GO:0031324 negative regulation of cellular metabolic process 28.5714 5 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0042127 regulation of cell population proliferation 28.5714 4 no
GO:0043065 positive regulation of apoptotic process 28.5714 6 no
GO:0043066 negative regulation of apoptotic process 28.5714 6 no
GO:0043068 positive regulation of programmed cell death 28.5714 5 no
GO:0043069 negative regulation of programmed cell death 28.5714 5 no
GO:0048585 negative regulation of response to stimulus 28.5714 4 no
GO:0051094 positive regulation of developmental process 28.5714 4 no
GO:1902533 positive regulation of intracellular signal transduction 28.5714 6 no
GO:0071702 organic substance transport 28.5714 4 no
GO:0071705 nitrogen compound transport 28.5714 4 no
GO:0001558 regulation of cell growth 21.4286 4 no
GO:0007043 cell-cell junction assembly 21.4286 6 no
GO:0009894 regulation of catabolic process 21.4286 4 no
GO:0010975 regulation of neuron projection development 21.4286 7 no
GO:0030030 cell projection organization 21.4286 4 no
GO:0030334 regulation of cell migration 21.4286 5 no
GO:0031175 neuron projection development 21.4286 6 no
GO:0031344 regulation of cell projection organization 21.4286 5 no
GO:0034329 cell junction assembly 21.4286 5 no
GO:0034330 cell junction organization 21.4286 4 no
GO:0040013 negative regulation of locomotion 21.4286 4 no
GO:0042176 regulation of protein catabolic process 21.4286 5 no
GO:0045216 cell-cell junction organization 21.4286 5 no
GO:0045893 positive regulation of DNA-templated transcription 21.4286 8 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 21.4286 5 no
GO:0048638 regulation of developmental growth 21.4286 4 no
GO:0050768 negative regulation of neurogenesis 21.4286 6 no
GO:0051223 regulation of protein transport 21.4286 5 no
GO:0051254 positive regulation of RNA metabolic process 21.4286 6 no
GO:0051961 negative regulation of nervous system development 21.4286 5 no
GO:0070201 regulation of establishment of protein localization 21.4286 6 no
GO:0071680 response to indole-3-methanol 21.4286 5 no
GO:0071681 cellular response to indole-3-methanol 21.4286 5 no
GO:0097305 response to alcohol 21.4286 4 no
GO:0097306 cellular response to alcohol 21.4286 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 21.4286 6 no
GO:0120036 plasma membrane bounded cell projection organization 21.4286 5 no
GO:1902680 positive regulation of RNA biosynthetic process 21.4286 7 no
GO:2000146 negative regulation of cell motility 21.4286 5 no
GO:0008285 negative regulation of cell population proliferation 21.4286 5 no
GO:0009059 macromolecule biosynthetic process 21.4286 4 no
GO:0009890 negative regulation of biosynthetic process 21.4286 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 21.4286 6 no
GO:0010564 regulation of cell cycle process 21.4286 5 no
GO:0010628 positive regulation of gene expression 21.4286 7 no
GO:0031327 negative regulation of cellular biosynthetic process 21.4286 6 no
GO:0031400 negative regulation of protein modification process 21.4286 7 no
GO:0043523 regulation of neuron apoptotic process 21.4286 6 no
GO:0043524 negative regulation of neuron apoptotic process 21.4286 7 no
GO:0050807 regulation of synapse organization 21.4286 5 no
GO:0050865 regulation of cell activation 21.4286 4 no
GO:0051248 negative regulation of protein metabolic process 21.4286 6 no
GO:0051726 regulation of cell cycle 21.4286 4 no
GO:0141124 intracellular signaling cassette 21.4286 4 no
GO:1902532 negative regulation of intracellular signal transduction 21.4286 6 no
GO:2001233 regulation of apoptotic signaling pathway 21.4286 5 no
GO:0043933 protein-containing complex organization 21.4286 4 no
GO:0044057 regulation of system process 21.4286 4 no
GO:0046903 secretion 21.4286 4 no
GO:0065003 protein-containing complex assembly 21.4286 5 no
GO:0030162 regulation of proteolysis 21.4286 6 no
GO:0043085 positive regulation of catalytic activity 21.4286 4 no
GO:0001932 regulation of protein phosphorylation 21.4286 7 no
GO:0006996 organelle organization 21.4286 4 no
GO:0007010 cytoskeleton organization 21.4286 5 no
GO:0019220 regulation of phosphate metabolic process 21.4286 6 no
GO:0042325 regulation of phosphorylation 21.4286 7 no
GO:0051174 regulation of phosphorus metabolic process 21.4286 5 no
GO:0015031 protein transport 21.4286 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PARD3_HUMAN [view interactions] High throughput no yes
MBPHL_HUMAN [view interactions] High throughput no no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
HMGA2_HUMAN [view interactions] High throughput no yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
RIMS1_HUMAN [view entry] [view interactions] High throughput yes yes
UBE2Z_HUMAN [view interactions] High throughput no yes
PKHA5_HUMAN [view entry] [view interactions] High throughput yes yes
EPHA1_HUMAN [view interactions] High throughput no yes
APOE_HUMAN [view entry] [view interactions] High throughput yes yes
NTRK1_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
MED9_HUMAN [view interactions] High throughput no no
ESR2_HUMAN [view interactions] High throughput no no
TRPV1_HUMAN [view entry] [view interactions] High throughput yes no
PKHA4_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
F16P1_HUMAN [view interactions] High throughput no no
ZMY19_HUMAN [view interactions] High throughput no yes
TCAL9_HUMAN [view interactions] High throughput no yes
KCTD9_HUMAN [view interactions] High throughput no no
PFD1_HUMAN [view interactions] High throughput no yes
ARMC8_HUMAN [view interactions] High throughput no yes
FOXA1_HUMAN [view interactions] High throughput no no
MYCN_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
UBE2H_HUMAN [view interactions] High throughput no yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
CTNA1_HUMAN [view entry] [view interactions] High throughput yes yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no