Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

KIF2B_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity (PubMed). Plays a role in chromosome congression (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in KIF2B_HUMAN
GO:0000166 nucleotide binding 33.3333 4 yes
GO:0005524 ATP binding 33.3333 5 yes
GO:0017076 purine nucleotide binding 33.3333 5 yes
GO:0030554 adenyl nucleotide binding 33.3333 6 yes
GO:0032555 purine ribonucleotide binding 33.3333 4 yes
GO:0032559 adenyl ribonucleotide binding 33.3333 5 yes
GO:0035639 purine ribonucleoside triphosphate binding 33.3333 4 yes
GO:0043168 anion binding 33.3333 4 yes
GO:0008017 microtubule binding 22.2222 5 yes
GO:0015631 tubulin binding 22.2222 4 yes
GO:0016462 pyrophosphatase activity 22.2222 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 22.2222 4 yes
GO:0016887 ATP hydrolysis activity 22.2222 7 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 22.2222 6 yes
GO:0043169 cation binding 22.2222 4 no
GO:0046872 metal ion binding 22.2222 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in KIF2B_HUMAN
GO:0043933 protein-containing complex organization 55.5556 4 yes
GO:0008104 protein localization 55.5556 4 no
GO:0006996 organelle organization 44.4444 4 yes
GO:0022411 cellular component disassembly 33.3333 4 yes
GO:0032984 protein-containing complex disassembly 33.3333 5 yes
GO:0015031 protein transport 33.3333 4 no
GO:0071702 organic substance transport 33.3333 4 no
GO:0071705 nitrogen compound transport 33.3333 4 no
GO:0010646 regulation of cell communication 33.3333 4 no
GO:0010647 positive regulation of cell communication 33.3333 5 no
GO:0023056 positive regulation of signaling 33.3333 4 no
GO:0048522 positive regulation of cellular process 33.3333 4 no
GO:0007010 cytoskeleton organization 22.2222 5 yes
GO:0007019 microtubule depolymerization 22.2222 5 yes
GO:0010564 regulation of cell cycle process 22.2222 5 yes
GO:0031109 microtubule polymerization or depolymerization 22.2222 4 yes
GO:0051261 protein depolymerization 22.2222 6 yes
GO:0051303 establishment of chromosome localization 22.2222 4 yes
GO:0051310 metaphase chromosome alignment 22.2222 5 yes
GO:0051726 regulation of cell cycle 22.2222 4 yes
GO:0051983 regulation of chromosome segregation 22.2222 6 yes
GO:0097435 supramolecular fiber organization 22.2222 4 yes
GO:0051128 regulation of cellular component organization 22.2222 4 no
GO:0009966 regulation of signal transduction 22.2222 4 no
GO:0009967 positive regulation of signal transduction 22.2222 5 no
GO:0022607 cellular component assembly 22.2222 4 no
GO:0035418 protein localization to synapse 22.2222 6 no
GO:0048584 positive regulation of response to stimulus 22.2222 4 no
GO:0050804 modulation of chemical synaptic transmission 22.2222 5 no
GO:0051259 protein complex oligomerization 22.2222 6 no
GO:0051262 protein tetramerization 22.2222 7 no
GO:0065003 protein-containing complex assembly 22.2222 5 no
GO:0099177 regulation of trans-synaptic signaling 22.2222 4 no
GO:1902414 protein localization to cell junction 22.2222 5 no
GO:0006892 post-Golgi vesicle-mediated transport 22.2222 4 no
GO:0006893 Golgi to plasma membrane transport 22.2222 4 no
GO:0032456 endocytic recycling 22.2222 4 no
GO:0009889 regulation of biosynthetic process 22.2222 4 no
GO:0010468 regulation of gene expression 22.2222 6 no
GO:0010556 regulation of macromolecule biosynthetic process 22.2222 5 no
GO:0031323 regulation of cellular metabolic process 22.2222 4 no
GO:0031326 regulation of cellular biosynthetic process 22.2222 5 no
GO:0048523 negative regulation of cellular process 22.2222 4 no
GO:0060255 regulation of macromolecule metabolic process 22.2222 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
BACH1_HUMAN [view interactions] High throughput no no
DAPK3_HUMAN [view interactions] High throughput no yes
CCD22_HUMAN [view entry] [view interactions] High throughput yes no
CDC27_HUMAN [view interactions] High throughput no yes
TXLNA_HUMAN [view interactions] High throughput no yes
RPB11_HUMAN [view interactions] High throughput no no
STK3_HUMAN [view interactions] High throughput no yes
CD046_HUMAN [view interactions] High throughput no no
CCD93_HUMAN [view entry] [view interactions] High throughput yes yes
CE170_HUMAN [view interactions] High throughput no yes
TM164_HUMAN [view interactions] High throughput no yes
COMD2_HUMAN [view interactions] High throughput no yes
KI18B_HUMAN [view interactions] High throughput no no
HOME1_HUMAN [view entry] [view interactions] High throughput yes yes
VPS8_HUMAN [view entry] [view interactions] High throughput yes yes
COMD1_HUMAN [view interactions] High throughput no yes
ANR52_HUMAN [view interactions] High throughput no yes
SPC24_HUMAN [view interactions] High throughput no no
CDC26_HUMAN [view interactions] High throughput no yes
APC16_HUMAN [view interactions] High throughput no yes
MIS12_HUMAN [view interactions] High throughput no yes
DSN1_HUMAN [view interactions] High throughput no yes
SAV1_HUMAN [view interactions] High throughput no yes
SPC25_HUMAN [view interactions] High throughput no no
TXLNG_HUMAN [view interactions] High throughput no no
ASB6_HUMAN [view interactions] High throughput no yes
COMD8_HUMAN [view interactions] High throughput no yes
COMD3_HUMAN [view interactions] High throughput no yes
CDC23_HUMAN [view interactions] High throughput no yes
FEM1B_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
MECOM_HUMAN [view interactions] High throughput no yes
H15_HUMAN [view interactions] High throughput no no
BICD2_HUMAN [view interactions] High throughput no yes
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
SIKE1_HUMAN [view interactions] High throughput no yes
C170B_HUMAN [view interactions] High throughput no yes
KLC4_HUMAN [view interactions] High throughput no yes
KLC1_HUMAN [view entry] [view interactions] High throughput yes no
CDC16_HUMAN [view interactions] High throughput no yes
STK4_HUMAN [view interactions] High throughput no yes
CF410_HUMAN [view interactions] High throughput no yes
KIF2C_HUMAN [view entry] [view interactions] High throughput yes no
WDR62_HUMAN [view interactions] High throughput no no
COMD6_HUMAN [view interactions] High throughput no no
NEK1_HUMAN [view interactions] High throughput no yes
RUNX1_HUMAN [view interactions] High throughput no yes
ACBG2_HUMAN [view interactions] High throughput no no
PAUF_HUMAN [view interactions] High throughput no no
HERC2_HUMAN [view interactions] High throughput no yes
UBE2H_HUMAN [view interactions] High throughput no yes
ACACA_HUMAN [view entry] [view interactions] High throughput yes yes