Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CLIP2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operate in the control of brain-specific organelle translocations . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CLIP2_HUMAN
GO:0043169 cation binding 50.0000 4 no
GO:0046872 metal ion binding 50.0000 5 no
GO:0008017 microtubule binding 33.3333 5 yes
GO:0015631 tubulin binding 33.3333 4 yes
GO:0019900 kinase binding 33.3333 4 no
GO:0019901 protein kinase binding 33.3333 5 no
GO:0051010 microtubule plus-end binding 27.7778 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in CLIP2_HUMAN
GO:0022607 cellular component assembly 66.6667 4 no
GO:0051128 regulation of cellular component organization 61.1111 4 no
GO:0048522 positive regulation of cellular process 55.5556 4 no
GO:0006996 organelle organization 50.0000 4 yes
GO:0008104 protein localization 50.0000 4 no
GO:0048523 negative regulation of cellular process 50.0000 4 no
GO:0010646 regulation of cell communication 44.4444 4 no
GO:0031323 regulation of cellular metabolic process 44.4444 4 no
GO:0009889 regulation of biosynthetic process 44.4444 4 no
GO:0031326 regulation of cellular biosynthetic process 38.8889 5 no
GO:0060255 regulation of macromolecule metabolic process 38.8889 4 no
GO:0007010 cytoskeleton organization 38.8889 5 yes
GO:0043933 protein-containing complex organization 38.8889 4 no
GO:0065003 protein-containing complex assembly 38.8889 5 no
GO:0010468 regulation of gene expression 38.8889 6 no
GO:0010556 regulation of macromolecule biosynthetic process 38.8889 5 no
GO:0051049 regulation of transport 33.3333 4 no
GO:0071702 organic substance transport 33.3333 4 no
GO:0071705 nitrogen compound transport 33.3333 4 no
GO:0044087 regulation of cellular component biogenesis 33.3333 4 no
GO:0009966 regulation of signal transduction 33.3333 4 no
GO:0031325 positive regulation of cellular metabolic process 27.7778 5 no
GO:0048585 negative regulation of response to stimulus 27.7778 4 no
GO:0051046 regulation of secretion 27.7778 5 no
GO:1903530 regulation of secretion by cell 27.7778 4 no
GO:0033043 regulation of organelle organization 27.7778 5 no
GO:0043254 regulation of protein-containing complex assembly 27.7778 5 no
GO:0051129 negative regulation of cellular component organization 27.7778 5 no
GO:0070925 organelle assembly 27.7778 5 no
GO:0009892 negative regulation of metabolic process 27.7778 4 no
GO:0009893 positive regulation of metabolic process 27.7778 4 no
GO:0010243 response to organonitrogen compound 27.7778 4 no
GO:0010604 positive regulation of macromolecule metabolic process 27.7778 5 no
GO:0010648 negative regulation of cell communication 22.2222 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 22.2222 5 no
GO:0019220 regulation of phosphate metabolic process 22.2222 6 no
GO:0023057 negative regulation of signaling 22.2222 4 no
GO:0030155 regulation of cell adhesion 22.2222 4 no
GO:0031324 negative regulation of cellular metabolic process 22.2222 5 no
GO:0032880 regulation of protein localization 22.2222 5 no
GO:0042127 regulation of cell population proliferation 22.2222 4 no
GO:0042325 regulation of phosphorylation 22.2222 7 no
GO:0050807 regulation of synapse organization 22.2222 5 no
GO:0050890 cognition 22.2222 4 no
GO:0051174 regulation of phosphorus metabolic process 22.2222 5 no
GO:0051252 regulation of RNA metabolic process 22.2222 5 no
GO:0060341 regulation of cellular localization 22.2222 4 no
GO:0071310 cellular response to organic substance 22.2222 4 no
GO:0071417 cellular response to organonitrogen compound 22.2222 4 no
GO:0080090 regulation of primary metabolic process 22.2222 4 no
GO:1901699 cellular response to nitrogen compound 22.2222 4 no
GO:1901701 cellular response to oxygen-containing compound 22.2222 4 no
GO:1902531 regulation of intracellular signal transduction 22.2222 5 no
GO:2001141 regulation of RNA biosynthetic process 22.2222 6 no
GO:0036211 protein modification process 22.2222 4 no
GO:0043412 macromolecule modification 22.2222 4 no
GO:0051047 positive regulation of secretion 22.2222 5 no
GO:0051050 positive regulation of transport 22.2222 4 no
GO:1903532 positive regulation of secretion by cell 22.2222 5 no
GO:0009891 positive regulation of biosynthetic process 22.2222 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 22.2222 6 no
GO:0015031 protein transport 22.2222 4 no
GO:0031328 positive regulation of cellular biosynthetic process 22.2222 6 no
GO:0045595 regulation of cell differentiation 22.2222 4 no
GO:0046903 secretion 22.2222 4 no
GO:2000145 regulation of cell motility 22.2222 4 no
GO:0032101 regulation of response to external stimulus 22.2222 4 no
GO:0097435 supramolecular fiber organization 22.2222 4 yes
GO:0030030 cell projection organization 22.2222 4 no
GO:0031110 regulation of microtubule polymerization or depolymerization 22.2222 6 no
GO:0031113 regulation of microtubule polymerization 22.2222 6 no
GO:0032271 regulation of protein polymerization 22.2222 6 no
GO:0032886 regulation of microtubule-based process 22.2222 4 no
GO:0044089 positive regulation of cellular component biogenesis 22.2222 5 no
GO:0051130 positive regulation of cellular component organization 22.2222 5 no
GO:0051225 spindle assembly 22.2222 4 no
GO:0051493 regulation of cytoskeleton organization 22.2222 6 no
GO:0070507 regulation of microtubule cytoskeleton organization 22.2222 5 no
GO:0140694 non-membrane-bounded organelle assembly 22.2222 6 no
GO:1902903 regulation of supramolecular fiber organization 22.2222 5 no
GO:0006355 regulation of DNA-templated transcription 22.2222 7 no
GO:0009890 negative regulation of biosynthetic process 22.2222 5 no
GO:0010605 negative regulation of macromolecule metabolic process 22.2222 5 no
GO:0031122 cytoplasmic microtubule organization 11.1111 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CLAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
CLAP2_HUMAN [view entry] [view interactions] Low throughput yes no
DYL1_HUMAN [view entry] [view interactions] High throughput yes no
KLC4_HUMAN [view interactions] High throughput no yes
TIM_HUMAN [view interactions] High throughput no yes
SIDT2_HUMAN [view interactions] High throughput no yes
MARE1_HUMAN [view entry] [view interactions] High throughput yes yes
DAAF5_HUMAN [view interactions] High throughput no no
CDC73_HUMAN [view interactions] High throughput no yes
BAP31_HUMAN [view interactions] High throughput no yes
MARE3_HUMAN [view entry] [view interactions] High throughput yes yes
MTR1A_HUMAN [view interactions] High throughput no no
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
GAB2_HUMAN [view interactions] High throughput no yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
MYOME_HUMAN [view interactions] High throughput no no
RYBP_HUMAN [view interactions] High throughput no no
RIMS1_HUMAN [view entry] [view interactions] High throughput yes yes
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
MD13L_HUMAN [view interactions] High throughput no no
MAX_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
KTNA1_HUMAN [view interactions] High throughput no yes
ITSN1_HUMAN [view entry] [view interactions] High throughput yes yes
NVL_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
VRK1_HUMAN [view interactions] High throughput no yes
APEX1_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
P53_HUMAN [view interactions] High throughput no no
TRIM9_HUMAN [view entry] [view interactions] High throughput yes no
TRI67_HUMAN [view interactions] High throughput no no
TF3C4_HUMAN [view interactions] High throughput no no
BORC6_HUMAN [view interactions] High throughput no yes
COMT_HUMAN [view entry] [view interactions] High throughput yes yes
TBB4B_HUMAN [view interactions] High throughput no yes
MSX2_HUMAN [view interactions] High throughput no no
ZRAN1_HUMAN [view interactions] High throughput no yes
DOT1L_HUMAN [view interactions] High throughput no yes
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
ADA10_HUMAN [view entry] [view interactions] High throughput yes yes
MIDN_HUMAN [view interactions] High throughput no no
NBEA_HUMAN [view entry] [view interactions] High throughput yes yes