Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CLIP2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operate in the control of brain-specific organelle translocations . [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CLIP2_HUMAN
GO:0008017 microtubule binding 42.8571 5 yes
GO:0015631 tubulin binding 42.8571 4 yes
GO:0051010 microtubule plus-end binding 35.7143 6 yes
GO:0046872 metal ion binding 35.7143 4 no
GO:0019900 kinase binding 35.7143 4 no
GO:0019901 protein kinase binding 35.7143 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in CLIP2_HUMAN
GO:0006996 organelle organization 57.1429 4 yes
GO:0051128 regulation of cellular component organization 50.0000 4 no
GO:0022607 cellular component assembly 50.0000 4 no
GO:0048523 negative regulation of cellular process 50.0000 4 no
GO:0007010 cytoskeleton organization 42.8571 5 yes
GO:0008104 protein localization 42.8571 4 no
GO:0048522 positive regulation of cellular process 42.8571 4 no
GO:0070925 organelle assembly 35.7143 5 no
GO:0010646 regulation of cell communication 28.5714 4 no
GO:0031110 regulation of microtubule polymerization or depolymerization 28.5714 6 no
GO:0031113 regulation of microtubule polymerization 28.5714 6 no
GO:0032271 regulation of protein polymerization 28.5714 6 no
GO:0032886 regulation of microtubule-based process 28.5714 4 no
GO:0033043 regulation of organelle organization 28.5714 5 no
GO:0043254 regulation of protein-containing complex assembly 28.5714 5 no
GO:0044087 regulation of cellular component biogenesis 28.5714 4 no
GO:0051049 regulation of transport 28.5714 4 no
GO:0051050 positive regulation of transport 28.5714 4 no
GO:0051129 negative regulation of cellular component organization 28.5714 5 no
GO:0051225 spindle assembly 28.5714 4 no
GO:0051493 regulation of cytoskeleton organization 28.5714 6 no
GO:0070507 regulation of microtubule cytoskeleton organization 28.5714 5 no
GO:0140694 non-membrane-bounded organelle assembly 28.5714 6 no
GO:1902903 regulation of supramolecular fiber organization 28.5714 5 no
GO:0010468 regulation of gene expression 28.5714 5 no
GO:0060255 regulation of macromolecule metabolic process 28.5714 4 no
GO:0031323 regulation of cellular metabolic process 28.5714 4 no
GO:0097435 supramolecular fiber organization 21.4286 4 yes
GO:0050807 regulation of synapse organization 21.4286 5 no
GO:0009966 regulation of signal transduction 21.4286 4 no
GO:0071702 organic substance transport 21.4286 4 no
GO:0071705 nitrogen compound transport 21.4286 4 no
GO:1902531 regulation of intracellular signal transduction 21.4286 5 no
GO:0007030 Golgi organization 21.4286 5 no
GO:0010639 negative regulation of organelle organization 21.4286 6 no
GO:0030155 regulation of cell adhesion 21.4286 4 no
GO:0031111 negative regulation of microtubule polymerization or depolymerization 21.4286 7 no
GO:0044089 positive regulation of cellular component biogenesis 21.4286 5 no
GO:0045595 regulation of cell differentiation 21.4286 4 no
GO:0048585 negative regulation of response to stimulus 21.4286 4 no
GO:0051046 regulation of secretion 21.4286 5 no
GO:0051047 positive regulation of secretion 21.4286 5 no
GO:0051130 positive regulation of cellular component organization 21.4286 5 no
GO:0051494 negative regulation of cytoskeleton organization 21.4286 7 no
GO:1902904 negative regulation of supramolecular fiber organization 21.4286 6 no
GO:1903530 regulation of secretion by cell 21.4286 4 no
GO:1903532 positive regulation of secretion by cell 21.4286 5 no
GO:0009893 positive regulation of metabolic process 21.4286 4 no
GO:0010604 positive regulation of macromolecule metabolic process 21.4286 5 no
GO:0006355 regulation of DNA-templated transcription 21.4286 6 no
GO:0009889 regulation of biosynthetic process 21.4286 4 no
GO:0010556 regulation of macromolecule biosynthetic process 21.4286 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 21.4286 5 no
GO:0019220 regulation of phosphate metabolic process 21.4286 6 no
GO:0031326 regulation of cellular biosynthetic process 21.4286 5 no
GO:0042325 regulation of phosphorylation 21.4286 7 no
GO:0051171 regulation of nitrogen compound metabolic process 21.4286 4 no
GO:0051174 regulation of phosphorus metabolic process 21.4286 5 no
GO:0051252 regulation of RNA metabolic process 21.4286 5 no
GO:0080090 regulation of primary metabolic process 21.4286 4 no
GO:1903506 regulation of nucleic acid-templated transcription 21.4286 7 no
GO:2001141 regulation of RNA biosynthetic process 21.4286 6 no
GO:0009892 negative regulation of metabolic process 21.4286 4 no
GO:0030030 cell projection organization 21.4286 4 no
GO:0031324 negative regulation of cellular metabolic process 21.4286 5 no
GO:0120036 plasma membrane bounded cell projection organization 21.4286 5 no
GO:0031122 cytoplasmic microtubule organization 14.2857 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CLAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
CLAP2_HUMAN [view entry] [view interactions] Low throughput yes no
DYL1_HUMAN [view entry] [view interactions] High throughput yes no
KLC4_HUMAN [view interactions] High throughput no yes
TIM_HUMAN [view interactions] High throughput no yes
SIDT2_HUMAN [view interactions] High throughput no yes
MARE1_HUMAN [view entry] [view interactions] High throughput yes yes
DAAF5_HUMAN [view interactions] High throughput no no
CDC73_HUMAN [view interactions] High throughput no yes
BAP31_HUMAN [view interactions] High throughput no yes
MARE3_HUMAN [view entry] [view interactions] High throughput yes yes
MTR1A_HUMAN [view interactions] High throughput no no
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
GAB2_HUMAN [view interactions] High throughput no yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
MYOME_HUMAN [view interactions] High throughput no no
RYBP_HUMAN [view interactions] High throughput no no
MAX_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
KTNA1_HUMAN [view interactions] High throughput no yes
ITSN1_HUMAN [view entry] [view interactions] High throughput yes yes
NVL_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
VRK1_HUMAN [view interactions] High throughput no yes
APEX1_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
P53_HUMAN [view interactions] High throughput no no
TRIM9_HUMAN [view entry] [view interactions] High throughput yes no
TRI67_HUMAN [view interactions] High throughput no no
TF3C4_HUMAN [view interactions] High throughput no no
BORC6_HUMAN [view interactions] High throughput no yes
COMT_HUMAN [view entry] [view interactions] High throughput yes yes
TBB4B_HUMAN [view interactions] High throughput no yes
NBEA_HUMAN [view entry] [view interactions] High throughput yes yes