Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SNPH_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Inhibits SNARE complex formation by absorbing free syntaxin-1. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SNPH_HUMAN
GO:0000166 nucleotide binding 44.4444 4 no
GO:0017076 purine nucleotide binding 44.4444 5 no
GO:0032555 purine ribonucleotide binding 44.4444 4 no
GO:0043168 anion binding 44.4444 4 no
GO:0035639 purine ribonucleoside triphosphate binding 33.3333 4 no
GO:0019900 kinase binding 33.3333 4 no
GO:0030554 adenyl nucleotide binding 33.3333 6 no
GO:0032559 adenyl ribonucleotide binding 33.3333 5 no
GO:0016462 pyrophosphatase activity 22.2222 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 22.2222 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 22.2222 6 no
GO:0043169 cation binding 22.2222 4 no
GO:0046872 metal ion binding 22.2222 5 no
GO:0031625 ubiquitin protein ligase binding 22.2222 5 no
GO:0044389 ubiquitin-like protein ligase binding 22.2222 4 no
GO:0008324 monoatomic cation transmembrane transporter activity 22.2222 4 no
GO:0022890 inorganic cation transmembrane transporter activity 22.2222 4 no
GO:0008017 microtubule binding 22.2222 5 no
GO:0015631 tubulin binding 22.2222 4 no
GO:0005524 ATP binding 22.2222 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in SNPH_HUMAN
GO:0006996 organelle organization 44.4444 4 no
GO:0044087 regulation of cellular component biogenesis 44.4444 4 no
GO:0048522 positive regulation of cellular process 44.4444 4 no
GO:0051128 regulation of cellular component organization 44.4444 4 no
GO:0022607 cellular component assembly 44.4444 4 no
GO:0007010 cytoskeleton organization 33.3333 5 no
GO:0009894 regulation of catabolic process 33.3333 4 no
GO:0009966 regulation of signal transduction 33.3333 4 no
GO:0010646 regulation of cell communication 33.3333 4 no
GO:0031323 regulation of cellular metabolic process 33.3333 4 no
GO:0036211 protein modification process 33.3333 4 no
GO:0043254 regulation of protein-containing complex assembly 33.3333 5 no
GO:0043412 macromolecule modification 33.3333 4 no
GO:0048523 negative regulation of cellular process 33.3333 4 no
GO:0048585 negative regulation of response to stimulus 33.3333 4 no
GO:0071310 cellular response to organic substance 33.3333 4 no
GO:0051046 regulation of secretion 33.3333 5 no
GO:0051047 positive regulation of secretion 33.3333 5 no
GO:0051049 regulation of transport 33.3333 4 no
GO:0051050 positive regulation of transport 33.3333 4 no
GO:1903530 regulation of secretion by cell 33.3333 4 no
GO:1903532 positive regulation of secretion by cell 33.3333 5 no
GO:0008104 protein localization 33.3333 4 no
GO:0043933 protein-containing complex organization 33.3333 4 no
GO:0023061 signal release 22.2222 4 yes
GO:0046903 secretion 22.2222 4 yes
GO:0048278 vesicle docking 22.2222 4 yes
GO:0099643 signal release from synapse 22.2222 5 yes
GO:0009893 positive regulation of metabolic process 22.2222 4 no
GO:0009968 negative regulation of signal transduction 22.2222 5 no
GO:0010648 negative regulation of cell communication 22.2222 5 no
GO:0023057 negative regulation of signaling 22.2222 4 no
GO:0030162 regulation of proteolysis 22.2222 6 no
GO:0031334 positive regulation of protein-containing complex assembly 22.2222 6 no
GO:0032446 protein modification by small protein conjugation 22.2222 7 no
GO:0034605 cellular response to heat 22.2222 4 no
GO:0042176 regulation of protein catabolic process 22.2222 5 no
GO:0043687 post-translational protein modification 22.2222 5 no
GO:0044089 positive regulation of cellular component biogenesis 22.2222 5 no
GO:0048584 positive regulation of response to stimulus 22.2222 4 no
GO:0051130 positive regulation of cellular component organization 22.2222 5 no
GO:0051246 regulation of protein metabolic process 22.2222 5 no
GO:0060255 regulation of macromolecule metabolic process 22.2222 4 no
GO:0061136 regulation of proteasomal protein catabolic process 22.2222 6 no
GO:0070647 protein modification by small protein conjugation or removal 22.2222 6 no
GO:0080090 regulation of primary metabolic process 22.2222 4 no
GO:0080134 regulation of response to stress 22.2222 4 no
GO:0090304 nucleic acid metabolic process 22.2222 4 no
GO:1903050 regulation of proteolysis involved in protein catabolic process 22.2222 7 no
GO:0006811 monoatomic ion transport 22.2222 4 no
GO:0006812 monoatomic cation transport 22.2222 5 no
GO:0006873 intracellular monoatomic ion homeostasis 22.2222 4 no
GO:0010506 regulation of autophagy 22.2222 6 no
GO:0016241 regulation of macroautophagy 22.2222 7 no
GO:0030003 intracellular monoatomic cation homeostasis 22.2222 5 no
GO:0031329 regulation of cellular catabolic process 22.2222 5 no
GO:0055080 monoatomic cation homeostasis 22.2222 4 no
GO:0098655 monoatomic cation transmembrane transport 22.2222 4 no
GO:0098657 import into cell 22.2222 4 no
GO:0098662 inorganic cation transmembrane transport 22.2222 4 no
GO:0007052 mitotic spindle organization 22.2222 4 no
GO:0017157 regulation of exocytosis 22.2222 5 no
GO:0030334 regulation of cell migration 22.2222 5 no
GO:0045595 regulation of cell differentiation 22.2222 4 no
GO:0045921 positive regulation of exocytosis 22.2222 6 no
GO:0051225 spindle assembly 22.2222 4 no
GO:0060627 regulation of vesicle-mediated transport 22.2222 4 no
GO:0070925 organelle assembly 22.2222 5 no
GO:0090307 mitotic spindle assembly 22.2222 5 no
GO:0097435 supramolecular fiber organization 22.2222 4 no
GO:0140694 non-membrane-bounded organelle assembly 22.2222 6 no
GO:1901888 regulation of cell junction assembly 22.2222 5 no
GO:1902850 microtubule cytoskeleton organization involved in mitosis 22.2222 4 no
GO:2000145 regulation of cell motility 22.2222 4 no
GO:0010243 response to organonitrogen compound 22.2222 4 no
GO:0065003 protein-containing complex assembly 22.2222 5 no
GO:0071417 cellular response to organonitrogen compound 22.2222 4 no
GO:1901699 cellular response to nitrogen compound 22.2222 4 no
GO:1901701 cellular response to oxygen-containing compound 22.2222 4 no
GO:0002791 regulation of peptide secretion 22.2222 6 no
GO:0006886 intracellular protein transport 22.2222 4 no
GO:0010647 positive regulation of cell communication 22.2222 5 no
GO:0015031 protein transport 22.2222 4 no
GO:0018193 peptidyl-amino acid modification 22.2222 5 no
GO:0023056 positive regulation of signaling 22.2222 4 no
GO:0032880 regulation of protein localization 22.2222 5 no
GO:0044057 regulation of system process 22.2222 4 no
GO:0046883 regulation of hormone secretion 22.2222 4 no
GO:0050708 regulation of protein secretion 22.2222 5 no
GO:0050796 regulation of insulin secretion 22.2222 6 no
GO:0050804 modulation of chemical synaptic transmission 22.2222 5 no
GO:0051223 regulation of protein transport 22.2222 5 no
GO:0060341 regulation of cellular localization 22.2222 4 no
GO:0070201 regulation of establishment of protein localization 22.2222 6 no
GO:0071702 organic substance transport 22.2222 4 no
GO:0071705 nitrogen compound transport 22.2222 4 no
GO:0090087 regulation of peptide transport 22.2222 5 no
GO:0090276 regulation of peptide hormone secretion 22.2222 5 no
GO:0099177 regulation of trans-synaptic signaling 22.2222 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
UBP7_HUMAN [view interactions] Low throughput no yes
CHIP_HUMAN [view entry] [view interactions] Low throughput yes yes
KIF2A_HUMAN [view entry] [view interactions] Low throughput yes yes
CLAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
TBB3_HUMAN [view entry] [view interactions] Low throughput yes yes
STX1A_HUMAN [view entry] [view interactions] Low throughput yes yes
KAPCA_HUMAN [view entry] [view interactions] Low throughput yes yes
ASF1A_HUMAN [view interactions] High throughput no no
HDAC4_HUMAN [view interactions] High throughput no yes
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
VATH_HUMAN [view entry] [view interactions] High throughput yes yes
XPA_HUMAN [view interactions] High throughput no yes
RHBD2_HUMAN [view interactions] High throughput no yes
SYBU_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes