Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

NRX3A_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI002288 LIG_PDZ_Class_2 LIG 1638 1643 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in NRX3A_HUMAN
GO:0042043 neurexin family protein binding 28.5714 4 no
GO:0046872 metal ion binding 9.5238 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in NRX3A_HUMAN
GO:0048522 positive regulation of cellular process 76.1905 4 no
GO:0010646 regulation of cell communication 71.4286 4 no
GO:0050804 modulation of chemical synaptic transmission 61.9048 5 no
GO:0099177 regulation of trans-synaptic signaling 61.9048 4 no
GO:0048523 negative regulation of cellular process 57.1429 4 no
GO:0051094 positive regulation of developmental process 57.1429 4 no
GO:0051128 regulation of cellular component organization 57.1429 4 no
GO:0051049 regulation of transport 57.1429 4 no
GO:0034330 cell junction organization 52.3810 4 no
GO:0050808 synapse organization 52.3810 5 no
GO:0050807 regulation of synapse organization 47.6190 5 no
GO:0051240 positive regulation of multicellular organismal process 47.6190 4 no
GO:2000026 regulation of multicellular organismal development 47.6190 4 no
GO:0009966 regulation of signal transduction 47.6190 4 no
GO:0007268 chemical synaptic transmission 42.8571 6 no
GO:0044087 regulation of cellular component biogenesis 42.8571 4 no
GO:0051130 positive regulation of cellular component organization 42.8571 5 no
GO:0051960 regulation of nervous system development 42.8571 5 no
GO:0051962 positive regulation of nervous system development 42.8571 5 no
GO:0098916 anterograde trans-synaptic signaling 42.8571 5 no
GO:0099537 trans-synaptic signaling 42.8571 4 no
GO:0010647 positive regulation of cell communication 42.8571 5 no
GO:0022607 cellular component assembly 42.8571 4 no
GO:0023056 positive regulation of signaling 42.8571 4 no
GO:0043269 regulation of ion transport 42.8571 5 no
GO:0048585 negative regulation of response to stimulus 38.0952 4 no
GO:0044089 positive regulation of cellular component biogenesis 38.0952 5 no
GO:0051963 regulation of synapse assembly 38.0952 6 no
GO:0051965 positive regulation of synapse assembly 38.0952 6 no
GO:1901888 regulation of cell junction assembly 38.0952 5 no
GO:1901890 positive regulation of cell junction assembly 38.0952 6 no
GO:0008104 protein localization 33.3333 4 no
GO:0044057 regulation of system process 33.3333 4 no
GO:0050806 positive regulation of synaptic transmission 33.3333 5 no
GO:0023057 negative regulation of signaling 28.5714 4 no
GO:0031644 regulation of nervous system process 28.5714 5 no
GO:0098815 modulation of excitatory postsynaptic potential 28.5714 4 no
GO:0016192 vesicle-mediated transport 28.5714 4 no
GO:0034762 regulation of transmembrane transport 28.5714 4 no
GO:0034765 regulation of ion transmembrane transport 28.5714 5 no
GO:0051050 positive regulation of transport 28.5714 4 no
GO:0051046 regulation of secretion 28.5714 5 no
GO:1903530 regulation of secretion by cell 28.5714 4 no
GO:0060627 regulation of vesicle-mediated transport 28.5714 4 no
GO:0007612 learning 28.5714 4 yes
GO:0050890 cognition 28.5714 4 yes
GO:0009968 negative regulation of signal transduction 28.5714 5 no
GO:0010648 negative regulation of cell communication 28.5714 5 no
GO:0033043 regulation of organelle organization 23.8095 5 no
GO:0051129 negative regulation of cellular component organization 23.8095 5 no
GO:0099175 regulation of postsynapse organization 23.8095 6 no
GO:0006897 endocytosis 23.8095 5 no
GO:0007416 synapse assembly 23.8095 6 no
GO:0009967 positive regulation of signal transduction 23.8095 5 no
GO:0022898 regulation of transmembrane transporter activity 23.8095 4 no
GO:0032412 regulation of ion transmembrane transporter activity 23.8095 5 no
GO:0034329 cell junction assembly 23.8095 5 no
GO:0048488 synaptic vesicle endocytosis 23.8095 5 no
GO:0048584 positive regulation of response to stimulus 23.8095 4 no
GO:0051966 regulation of synaptic transmission, glutamatergic 23.8095 6 no
GO:0099003 vesicle-mediated transport in synapse 23.8095 5 no
GO:0099054 presynapse assembly 23.8095 5 no
GO:0099172 presynapse organization 23.8095 4 no
GO:0140238 presynaptic endocytosis 23.8095 4 no
GO:1904062 regulation of cation transmembrane transport 23.8095 6 no
GO:0009893 positive regulation of metabolic process 23.8095 4 no
GO:0010604 positive regulation of macromolecule metabolic process 23.8095 5 no
GO:0022603 regulation of anatomical structure morphogenesis 23.8095 4 no
GO:0031323 regulation of cellular metabolic process 23.8095 4 no
GO:0031325 positive regulation of cellular metabolic process 23.8095 5 no
GO:0051171 regulation of nitrogen compound metabolic process 23.8095 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 23.8095 5 no
GO:0060255 regulation of macromolecule metabolic process 23.8095 4 no
GO:0080090 regulation of primary metabolic process 23.8095 4 no
GO:0035418 protein localization to synapse 23.8095 6 no
GO:1902414 protein localization to cell junction 23.8095 5 no
GO:0007158 neuron cell-cell adhesion 23.8095 4 yes
GO:0030030 cell projection organization 14.2857 4 yes
GO:0031175 neuron projection development 14.2857 6 yes
GO:0120036 plasma membrane bounded cell projection organization 14.2857 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
AFAD_HUMAN [view interactions] Low throughput no yes
PTPRT_HUMAN [view entry] [view interactions] Low throughput yes yes
CSKP_HUMAN [view entry] [view interactions] Low throughput yes yes
LRRT2_HUMAN [view entry] [view interactions] Low throughput yes no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
PDPK1_HUMAN [view entry] [view interactions] High throughput yes yes
MYC_HUMAN [view interactions] High throughput no yes
RPB2_HUMAN [view interactions] High throughput no yes
SHAN1_HUMAN [view entry] [view interactions] Computational yes yes
LRRT3_HUMAN [view entry] [view interactions] Computational yes no
NLGN2_HUMAN [view entry] [view interactions] Computational yes yes
NLGN1_HUMAN [view entry] [view interactions] Computational yes yes
NLGNX_HUMAN [view entry] [view interactions] Computational yes yes
DLG2_HUMAN [view entry] [view interactions] Computational yes yes
LRRT4_HUMAN [view entry] [view interactions] Computational yes no
NLGN3_HUMAN [view entry] [view interactions] Computational yes yes
SYT1_HUMAN [view entry] [view interactions] Computational yes no
SHAN2_HUMAN [view entry] [view interactions] Computational yes yes
APBA1_HUMAN [view interactions] Computational no no
EPB41_HUMAN [view entry] [view interactions] Computational yes no
GRM5_HUMAN [view entry] [view interactions] Computational yes no
CBLN1_HUMAN [view entry] [view interactions] Computational yes no
GRID2_HUMAN [view entry] [view interactions] Computational yes no
LRRT1_HUMAN [view entry] [view interactions] Computational yes yes
NXPH1_HUMAN [view interactions] Computational no no