Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SLIK3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Suppresses neurite outgrowth. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SLIK3_HUMAN
GO:0017076 purine nucleotide binding 42.8571 4 no
GO:0032555 purine ribonucleotide binding 42.8571 4 no
GO:0035639 purine ribonucleoside triphosphate binding 42.8571 4 no
GO:0003924 GTPase activity 28.5714 7 no
GO:0005525 GTP binding 28.5714 5 no
GO:0016462 pyrophosphatase activity 28.5714 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 28.5714 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 28.5714 6 no
GO:0019001 guanyl nucleotide binding 28.5714 5 no
GO:0032561 guanyl ribonucleotide binding 28.5714 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in SLIK3_HUMAN
GO:0048522 positive regulation of cellular process 85.7143 4 yes
GO:0051128 regulation of cellular component organization 71.4286 4 yes
GO:0051094 positive regulation of developmental process 57.1429 4 yes
GO:0099537 trans-synaptic signaling 57.1429 4 yes
GO:2000026 regulation of multicellular organismal development 57.1429 4 yes
GO:0009966 regulation of signal transduction 57.1429 4 no
GO:0010646 regulation of cell communication 57.1429 4 no
GO:0007268 chemical synaptic transmission 42.8571 6 yes
GO:0030030 cell projection organization 42.8571 4 yes
GO:0044087 regulation of cellular component biogenesis 42.8571 4 yes
GO:0044089 positive regulation of cellular component biogenesis 42.8571 5 yes
GO:0050807 regulation of synapse organization 42.8571 5 yes
GO:0051130 positive regulation of cellular component organization 42.8571 5 yes
GO:0051240 positive regulation of multicellular organismal process 42.8571 4 yes
GO:0051932 synaptic transmission, GABAergic 42.8571 7 yes
GO:0051960 regulation of nervous system development 42.8571 5 yes
GO:0051962 positive regulation of nervous system development 42.8571 5 yes
GO:0051963 regulation of synapse assembly 42.8571 6 yes
GO:0051965 positive regulation of synapse assembly 42.8571 6 yes
GO:0098916 anterograde trans-synaptic signaling 42.8571 5 yes
GO:0099174 regulation of presynapse organization 42.8571 6 yes
GO:1901888 regulation of cell junction assembly 42.8571 5 yes
GO:1901890 positive regulation of cell junction assembly 42.8571 6 yes
GO:1905606 regulation of presynapse assembly 42.8571 7 yes
GO:0048523 negative regulation of cellular process 42.8571 4 no
GO:0051049 regulation of transport 42.8571 4 no
GO:0051050 positive regulation of transport 42.8571 4 no
GO:0008284 positive regulation of cell population proliferation 42.8571 5 no
GO:0022603 regulation of anatomical structure morphogenesis 42.8571 4 no
GO:0042127 regulation of cell population proliferation 42.8571 4 no
GO:0045595 regulation of cell differentiation 42.8571 4 no
GO:0022607 cellular component assembly 42.8571 4 no
GO:0008104 protein localization 28.5714 4 yes
GO:0035418 protein localization to synapse 28.5714 6 yes
GO:0043113 receptor clustering 28.5714 5 yes
GO:0072553 terminal button organization 28.5714 5 yes
GO:0072578 neurotransmitter-gated ion channel clustering 28.5714 6 yes
GO:0072657 protein localization to membrane 28.5714 4 yes
GO:0097116 gephyrin clustering involved in postsynaptic density assembly 28.5714 7 yes
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 28.5714 4 yes
GO:0099172 presynapse organization 28.5714 4 yes
GO:0099560 synaptic membrane adhesion 28.5714 5 yes
GO:1902414 protein localization to cell junction 28.5714 5 yes
GO:0006355 regulation of DNA-templated transcription 28.5714 6 no
GO:0007600 sensory perception 28.5714 4 no
GO:0009889 regulation of biosynthetic process 28.5714 4 no
GO:0009893 positive regulation of metabolic process 28.5714 4 no
GO:0009968 negative regulation of signal transduction 28.5714 5 no
GO:0010468 regulation of gene expression 28.5714 5 no
GO:0010556 regulation of macromolecule biosynthetic process 28.5714 5 no
GO:0010604 positive regulation of macromolecule metabolic process 28.5714 5 no
GO:0010648 negative regulation of cell communication 28.5714 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 28.5714 5 no
GO:0023057 negative regulation of signaling 28.5714 4 no
GO:0031323 regulation of cellular metabolic process 28.5714 4 no
GO:0031326 regulation of cellular biosynthetic process 28.5714 5 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0031401 positive regulation of protein modification process 28.5714 7 no
GO:0043269 regulation of ion transport 28.5714 5 no
GO:0045927 positive regulation of growth 28.5714 4 no
GO:0048585 negative regulation of response to stimulus 28.5714 4 no
GO:0051171 regulation of nitrogen compound metabolic process 28.5714 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 28.5714 5 no
GO:0051246 regulation of protein metabolic process 28.5714 5 no
GO:0051247 positive regulation of protein metabolic process 28.5714 6 no
GO:0051252 regulation of RNA metabolic process 28.5714 5 no
GO:0060255 regulation of macromolecule metabolic process 28.5714 4 no
GO:0080090 regulation of primary metabolic process 28.5714 4 no
GO:1902531 regulation of intracellular signal transduction 28.5714 5 no
GO:1903506 regulation of nucleic acid-templated transcription 28.5714 7 no
GO:2001141 regulation of RNA biosynthetic process 28.5714 6 no
GO:0006796 phosphate-containing compound metabolic process 28.5714 4 no
GO:0007167 enzyme-linked receptor protein signaling pathway 28.5714 4 no
GO:0009967 positive regulation of signal transduction 28.5714 5 no
GO:0010647 positive regulation of cell communication 28.5714 5 no
GO:0023056 positive regulation of signaling 28.5714 4 no
GO:0030155 regulation of cell adhesion 28.5714 4 no
GO:0030182 neuron differentiation 28.5714 4 no
GO:0031175 neuron projection development 28.5714 6 no
GO:0032880 regulation of protein localization 28.5714 5 no
GO:0034330 cell junction organization 28.5714 4 no
GO:0036211 protein modification process 28.5714 4 no
GO:0043412 macromolecule modification 28.5714 4 no
GO:0045785 positive regulation of cell adhesion 28.5714 5 no
GO:0048584 positive regulation of response to stimulus 28.5714 4 no
GO:0050678 regulation of epithelial cell proliferation 28.5714 5 no
GO:0050679 positive regulation of epithelial cell proliferation 28.5714 6 no
GO:0050808 synapse organization 28.5714 5 no
GO:0051222 positive regulation of protein transport 28.5714 5 no
GO:0051223 regulation of protein transport 28.5714 5 no
GO:0060341 regulation of cellular localization 28.5714 4 no
GO:0070201 regulation of establishment of protein localization 28.5714 6 no
GO:0120036 plasma membrane bounded cell projection organization 28.5714 5 no
GO:1903829 positive regulation of protein localization 28.5714 5 no
GO:1904951 positive regulation of establishment of protein localization 28.5714 6 no
GO:1905475 regulation of protein localization to membrane 28.5714 6 no
GO:1905477 positive regulation of protein localization to membrane 28.5714 6 no
GO:0007264 small GTPase mediated signal transduction 28.5714 4 no
GO:0010720 positive regulation of cell development 28.5714 6 no
GO:0010769 regulation of cell morphogenesis involved in differentiation 28.5714 6 no
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 28.5714 7 no
GO:0022604 regulation of cell morphogenesis 28.5714 5 no
GO:0033043 regulation of organelle organization 28.5714 5 no
GO:0045597 positive regulation of cell differentiation 28.5714 5 no
GO:0050804 modulation of chemical synaptic transmission 28.5714 5 no
GO:0060284 regulation of cell development 28.5714 5 no
GO:0061024 membrane organization 28.5714 4 no
GO:0071709 membrane assembly 28.5714 5 no
GO:0097090 presynaptic membrane organization 28.5714 5 no
GO:0097105 presynaptic membrane assembly 28.5714 6 no
GO:0099177 regulation of trans-synaptic signaling 28.5714 4 no
GO:0050885 neuromuscular process controlling balance 28.5714 5 no
GO:0050905 neuromuscular process 28.5714 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
H32_HUMAN [view interactions] High throughput no yes
H12_HUMAN [view interactions] High throughput no yes
H2B1H_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
WFS1_HUMAN [view entry] [view interactions] High throughput yes yes
TRI54_HUMAN [view interactions] High throughput no no
KDM5B_HUMAN [view interactions] High throughput no no
HNRPL_HUMAN [view interactions] High throughput no yes
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
PCDG7_HUMAN [view interactions] High throughput no no
KCNT2_HUMAN [view interactions] High throughput no no
TCAF2_HUMAN [view interactions] High throughput no no
AVR2A_HUMAN [view interactions] High throughput no yes
VAMP4_HUMAN [view interactions] High throughput no yes
ATE1_HUMAN [view interactions] High throughput no yes
CNPY3_HUMAN [view interactions] High throughput no yes
KCNE3_HUMAN [view interactions] High throughput no yes
RHDF2_HUMAN [view interactions] High throughput no yes
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
CSK_HUMAN [view interactions] High throughput no yes
RASN_HUMAN [view entry] [view interactions] High throughput yes no
PTPRD_HUMAN [view entry] [view interactions] Computational yes no
NLGN2_HUMAN [view entry] [view interactions] Computational yes yes