NLGNX_HUMAN
Putative neuronal cell surface protein involved in cell-cell-interactions. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI004104 | LIG_WRC_WIRS_1 | LIG | 795 | 800 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in NLGNX_HUMAN |
---|---|---|---|---|
GO:0097109 | neuroligin family protein binding | 30.7692 | 4 | no |
GO:0042043 | neurexin family protein binding | 23.0769 | 4 | yes |
GO:0035254 | glutamate receptor binding | 23.0769 | 4 | no |
GO:0035255 | ionotropic glutamate receptor binding | 23.0769 | 5 | no |
GO:0046872 | metal ion binding | 23.0769 | 4 | no |
GO:0031404 | chloride ion binding | 15.3846 | 4 | yes |
GO:0042803 | protein homodimerization activity | 15.3846 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in NLGNX_HUMAN |
---|---|---|---|---|
GO:0007612 | learning | 76.9231 | 4 | yes |
GO:0050890 | cognition | 76.9231 | 4 | yes |
GO:0099177 | regulation of trans-synaptic signaling | 61.5385 | 4 | yes |
GO:0009966 | regulation of signal transduction | 61.5385 | 4 | yes |
GO:0010646 | regulation of cell communication | 61.5385 | 4 | yes |
GO:0022607 | cellular component assembly | 61.5385 | 4 | yes |
GO:0050804 | modulation of chemical synaptic transmission | 61.5385 | 5 | yes |
GO:0098916 | anterograde trans-synaptic signaling | 53.8462 | 5 | yes |
GO:0099537 | trans-synaptic signaling | 53.8462 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 53.8462 | 4 | no |
GO:0007268 | chemical synaptic transmission | 53.8462 | 6 | yes |
GO:0031644 | regulation of nervous system process | 53.8462 | 5 | yes |
GO:0034330 | cell junction organization | 53.8462 | 4 | yes |
GO:0044057 | regulation of system process | 53.8462 | 4 | yes |
GO:0050808 | synapse organization | 53.8462 | 5 | yes |
GO:0098815 | modulation of excitatory postsynaptic potential | 46.1538 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 46.1538 | 4 | no |
GO:0008104 | protein localization | 46.1538 | 4 | no |
GO:0007158 | neuron cell-cell adhesion | 46.1538 | 4 | yes |
GO:0061024 | membrane organization | 46.1538 | 4 | yes |
GO:0097104 | postsynaptic membrane assembly | 38.4615 | 6 | yes |
GO:0010647 | positive regulation of cell communication | 38.4615 | 5 | no |
GO:0023056 | positive regulation of signaling | 38.4615 | 4 | no |
GO:0030030 | cell projection organization | 38.4615 | 4 | no |
GO:0031175 | neuron projection development | 38.4615 | 6 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 38.4615 | 5 | no |
GO:0001941 | postsynaptic membrane organization | 38.4615 | 5 | yes |
GO:0048523 | negative regulation of cellular process | 38.4615 | 4 | yes |
GO:0071709 | membrane assembly | 38.4615 | 5 | yes |
GO:0007416 | synapse assembly | 30.7692 | 6 | no |
GO:0009967 | positive regulation of signal transduction | 30.7692 | 5 | no |
GO:0034329 | cell junction assembly | 30.7692 | 5 | no |
GO:0044087 | regulation of cellular component biogenesis | 30.7692 | 4 | no |
GO:0048584 | positive regulation of response to stimulus | 30.7692 | 4 | no |
GO:0050806 | positive regulation of synaptic transmission | 30.7692 | 5 | no |
GO:0051094 | positive regulation of developmental process | 30.7692 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 30.7692 | 5 | no |
GO:0099601 | regulation of neurotransmitter receptor activity | 30.7692 | 4 | no |
GO:2000463 | positive regulation of excitatory postsynaptic potential | 30.7692 | 5 | no |
GO:0035418 | protein localization to synapse | 30.7692 | 6 | no |
GO:1902414 | protein localization to cell junction | 30.7692 | 5 | no |
GO:0016192 | vesicle-mediated transport | 30.7692 | 4 | yes |
GO:0097105 | presynaptic membrane assembly | 23.0769 | 6 | yes |
GO:0099003 | vesicle-mediated transport in synapse | 23.0769 | 5 | yes |
GO:0099054 | presynapse assembly | 23.0769 | 5 | yes |
GO:0099172 | presynapse organization | 23.0769 | 4 | yes |
GO:0140238 | presynaptic endocytosis | 23.0769 | 4 | yes |
GO:0022898 | regulation of transmembrane transporter activity | 23.0769 | 4 | no |
GO:0032412 | regulation of ion transmembrane transporter activity | 23.0769 | 5 | no |
GO:0034762 | regulation of transmembrane transport | 23.0769 | 4 | no |
GO:0034765 | regulation of ion transmembrane transport | 23.0769 | 5 | no |
GO:0043269 | regulation of ion transport | 23.0769 | 5 | no |
GO:0044089 | positive regulation of cellular component biogenesis | 23.0769 | 5 | no |
GO:0050807 | regulation of synapse organization | 23.0769 | 5 | no |
GO:0051049 | regulation of transport | 23.0769 | 4 | no |
GO:1901888 | regulation of cell junction assembly | 23.0769 | 5 | no |
GO:1901890 | positive regulation of cell junction assembly | 23.0769 | 6 | no |
GO:1904062 | regulation of cation transmembrane transport | 23.0769 | 6 | no |
GO:2001257 | regulation of cation channel activity | 23.0769 | 6 | no |
GO:0032990 | cell part morphogenesis | 23.0769 | 4 | no |
GO:0043113 | receptor clustering | 23.0769 | 5 | no |
GO:0048812 | neuron projection morphogenesis | 23.0769 | 7 | no |
GO:0048858 | cell projection morphogenesis | 23.0769 | 5 | no |
GO:0050885 | neuromuscular process controlling balance | 23.0769 | 5 | no |
GO:0050905 | neuromuscular process | 23.0769 | 4 | no |
GO:0072657 | protein localization to membrane | 23.0769 | 4 | no |
GO:0120039 | plasma membrane bounded cell projection morphogenesis | 23.0769 | 6 | no |
GO:0031223 | auditory behavior | 23.0769 | 4 | no |
GO:0042297 | vocal learning | 23.0769 | 5 | no |
GO:0098596 | imitative learning | 23.0769 | 6 | no |
GO:0098597 | observational learning | 23.0769 | 5 | no |
GO:0098598 | learned vocalization behavior or vocal learning | 23.0769 | 4 | no |
GO:0006897 | endocytosis | 23.0769 | 5 | yes |
GO:0009968 | negative regulation of signal transduction | 23.0769 | 5 | yes |
GO:0010648 | negative regulation of cell communication | 23.0769 | 5 | yes |
GO:0023057 | negative regulation of signaling | 23.0769 | 4 | yes |
GO:0048488 | synaptic vesicle endocytosis | 23.0769 | 5 | yes |
GO:0048585 | negative regulation of response to stimulus | 23.0769 | 4 | yes |
GO:0050805 | negative regulation of synaptic transmission | 23.0769 | 5 | yes |
GO:0097090 | presynaptic membrane organization | 23.0769 | 5 | yes |
GO:0030182 | neuron differentiation | 15.3846 | 4 | yes |
GO:0045216 | cell-cell junction organization | 15.3846 | 5 | yes |
GO:0090394 | negative regulation of excitatory postsynaptic potential | 15.3846 | 5 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NLGNX_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BRK1_HUMAN | [view interactions] | High throughput | no | no |
NLGN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CNTP2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NRX1A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
DLGP2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
NRX3A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SHAN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SHAN2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NRX2A_HUMAN | [view entry] [view interactions] | Computational | yes | no |