Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

NLGNX_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Putative neuronal cell surface protein involved in cell-cell-interactions. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI004104 LIG_WRC_WIRS_1 LIG 795 800 -
ELMI004104 LIG_WRC_WIRS_1 LIG 795 800 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in NLGNX_HUMAN
GO:0042043 neurexin family protein binding 42.8571 4 yes
GO:0043168 anion binding 42.8571 4 yes
GO:0031404 chloride ion binding 28.5714 5 yes
GO:0042803 protein homodimerization activity 28.5714 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in NLGNX_HUMAN
GO:0044057 regulation of system process 71.4286 4 yes
GO:0007268 chemical synaptic transmission 57.1429 7 yes
GO:0007612 learning 57.1429 4 yes
GO:0009966 regulation of signal transduction 57.1429 4 yes
GO:0010646 regulation of cell communication 57.1429 4 yes
GO:0022607 cellular component assembly 57.1429 4 yes
GO:0031644 regulation of nervous system process 57.1429 5 yes
GO:0050804 modulation of chemical synaptic transmission 57.1429 5 yes
GO:0050890 cognition 57.1429 4 yes
GO:0098657 import into cell 57.1429 4 yes
GO:0098815 modulation of excitatory postsynaptic potential 57.1429 4 yes
GO:0098916 anterograde trans-synaptic signaling 57.1429 6 yes
GO:0099177 regulation of trans-synaptic signaling 57.1429 4 yes
GO:0099536 synaptic signaling 57.1429 4 yes
GO:0099537 trans-synaptic signaling 57.1429 5 yes
GO:0001941 postsynaptic membrane organization 42.8571 5 yes
GO:0007158 neuron cell-cell adhesion 42.8571 4 yes
GO:0034330 cell junction organization 42.8571 4 yes
GO:0048488 synaptic vesicle endocytosis 42.8571 5 yes
GO:0050808 synapse organization 42.8571 5 yes
GO:0061024 membrane organization 42.8571 4 yes
GO:0071709 membrane assembly 42.8571 5 yes
GO:0097090 presynaptic membrane organization 42.8571 5 yes
GO:0097104 postsynaptic membrane assembly 42.8571 6 yes
GO:0097105 presynaptic membrane assembly 42.8571 6 yes
GO:0099054 presynapse assembly 42.8571 5 yes
GO:0099172 presynapse organization 42.8571 4 yes
GO:0140238 presynaptic endocytosis 42.8571 4 yes
GO:0034762 regulation of transmembrane transport 42.8571 4 no
GO:0051049 regulation of transport 42.8571 4 no
GO:0048522 positive regulation of cellular process 42.8571 4 no
GO:0030182 neuron differentiation 28.5714 4 yes
GO:0045216 cell-cell junction organization 28.5714 5 yes
GO:0090394 negative regulation of excitatory postsynaptic potential 28.5714 4 yes
GO:0034765 regulation of monoatomic ion transmembrane transport 28.5714 5 no
GO:0043085 positive regulation of catalytic activity 28.5714 4 no
GO:0043269 regulation of monoatomic ion transport 28.5714 5 no
GO:0141124 intracellular signaling cassette 28.5714 4 no
GO:0008104 protein localization 28.5714 4 no
GO:0009967 positive regulation of signal transduction 28.5714 5 no
GO:0010647 positive regulation of cell communication 28.5714 5 no
GO:0022898 regulation of transmembrane transporter activity 28.5714 4 no
GO:0023056 positive regulation of signaling 28.5714 4 no
GO:0032412 regulation of monoatomic ion transmembrane transporter activity 28.5714 5 no
GO:0048584 positive regulation of response to stimulus 28.5714 4 no
GO:0050806 positive regulation of synaptic transmission 28.5714 5 no
GO:0051094 positive regulation of developmental process 28.5714 4 no
GO:0051128 regulation of cellular component organization 28.5714 4 no
GO:0051130 positive regulation of cellular component organization 28.5714 5 no
GO:0099601 regulation of neurotransmitter receptor activity 28.5714 4 no
GO:2000463 positive regulation of excitatory postsynaptic potential 28.5714 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
NLGNX_HUMAN [view entry] [view interactions] Low throughput yes yes
BRK1_HUMAN [view interactions] High throughput no no
CAC1C_HUMAN [view entry] [view interactions] High throughput yes no
NLGN3_HUMAN [view entry] [view interactions] High throughput yes yes
SNX27_HUMAN [view entry] [view interactions] High throughput yes no
SPPL3_HUMAN [view interactions] High throughput no no
RASN_HUMAN [view entry] [view interactions] High throughput yes no