Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SLIK5_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Suppresses neurite outgrowth. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SLIK5_HUMAN
GO:0000166 nucleotide binding 48.0000 4 no
GO:0017076 purine nucleotide binding 48.0000 5 no
GO:0032555 purine ribonucleotide binding 48.0000 4 no
GO:0035639 purine ribonucleoside triphosphate binding 48.0000 4 no
GO:0043168 anion binding 48.0000 4 no
GO:0003924 GTPase activity 40.0000 7 no
GO:0005525 GTP binding 40.0000 5 no
GO:0016462 pyrophosphatase activity 40.0000 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 40.0000 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 40.0000 6 no
GO:0019001 guanyl nucleotide binding 40.0000 6 no
GO:0032561 guanyl ribonucleotide binding 40.0000 5 no
GO:0019900 kinase binding 28.0000 4 no
GO:0019901 protein kinase binding 24.0000 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in SLIK5_HUMAN
GO:0048522 positive regulation of cellular process 76.0000 4 yes
GO:0051128 regulation of cellular component organization 68.0000 4 yes
GO:0044087 regulation of cellular component biogenesis 48.0000 4 yes
GO:0010646 regulation of cell communication 48.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 44.0000 4 no
GO:0051130 positive regulation of cellular component organization 44.0000 5 yes
GO:0031344 regulation of cell projection organization 44.0000 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 40.0000 6 no
GO:0030030 cell projection organization 40.0000 4 yes
GO:0051094 positive regulation of developmental process 40.0000 4 yes
GO:0141124 intracellular signaling cassette 40.0000 4 no
GO:0022603 regulation of anatomical structure morphogenesis 40.0000 4 no
GO:0031323 regulation of cellular metabolic process 40.0000 4 no
GO:0080090 regulation of primary metabolic process 36.0000 4 no
GO:0008104 protein localization 36.0000 4 no
GO:0050807 regulation of synapse organization 36.0000 5 yes
GO:0051240 positive regulation of multicellular organismal process 36.0000 4 yes
GO:2000026 regulation of multicellular organismal development 36.0000 4 yes
GO:0007264 small GTPase-mediated signal transduction 36.0000 5 no
GO:0042127 regulation of cell population proliferation 36.0000 4 no
GO:0006996 organelle organization 36.0000 4 no
GO:0009893 positive regulation of metabolic process 36.0000 4 no
GO:0009966 regulation of signal transduction 36.0000 4 no
GO:0010604 positive regulation of macromolecule metabolic process 36.0000 5 no
GO:0022607 cellular component assembly 36.0000 4 no
GO:0048584 positive regulation of response to stimulus 36.0000 4 no
GO:0097435 supramolecular fiber organization 32.0000 4 no
GO:0120036 plasma membrane bounded cell projection organization 32.0000 5 no
GO:0050804 modulation of chemical synaptic transmission 32.0000 5 no
GO:0099177 regulation of trans-synaptic signaling 32.0000 4 no
GO:0044089 positive regulation of cellular component biogenesis 32.0000 5 yes
GO:0008284 positive regulation of cell population proliferation 32.0000 5 no
GO:0007010 cytoskeleton organization 32.0000 5 no
GO:0009889 regulation of biosynthetic process 32.0000 4 no
GO:0009967 positive regulation of signal transduction 32.0000 5 no
GO:0010468 regulation of gene expression 32.0000 6 no
GO:0010556 regulation of macromolecule biosynthetic process 32.0000 5 no
GO:0010647 positive regulation of cell communication 32.0000 5 no
GO:0023056 positive regulation of signaling 32.0000 4 no
GO:0031326 regulation of cellular biosynthetic process 32.0000 5 no
GO:0033043 regulation of organelle organization 32.0000 5 no
GO:0048523 negative regulation of cellular process 32.0000 4 no
GO:0061024 membrane organization 28.0000 4 no
GO:2000145 regulation of cell motility 28.0000 4 no
GO:0045595 regulation of cell differentiation 28.0000 4 no
GO:0060284 regulation of cell development 28.0000 5 no
GO:1901888 regulation of cell junction assembly 28.0000 5 yes
GO:0007015 actin filament organization 28.0000 5 no
GO:0030334 regulation of cell migration 28.0000 5 no
GO:0031175 neuron projection development 28.0000 6 no
GO:0031325 positive regulation of cellular metabolic process 28.0000 5 no
GO:0031346 positive regulation of cell projection organization 28.0000 6 no
GO:0051049 regulation of transport 24.0000 4 no
GO:0051246 regulation of protein metabolic process 24.0000 5 no
GO:0051247 positive regulation of protein metabolic process 24.0000 6 no
GO:0060491 regulation of cell projection assembly 24.0000 5 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 24.0000 6 no
GO:1902531 regulation of intracellular signal transduction 24.0000 5 no
GO:2000147 positive regulation of cell motility 24.0000 5 no
GO:0045597 positive regulation of cell differentiation 24.0000 5 no
GO:0042981 regulation of apoptotic process 24.0000 5 no
GO:0043067 regulation of programmed cell death 24.0000 4 no
GO:0051960 regulation of nervous system development 24.0000 5 yes
GO:0051962 positive regulation of nervous system development 24.0000 5 yes
GO:0099536 synaptic signaling 24.0000 4 yes
GO:0099537 trans-synaptic signaling 24.0000 5 yes
GO:0010810 regulation of cell-substrate adhesion 24.0000 5 no
GO:0030155 regulation of cell adhesion 24.0000 4 no
GO:0030335 positive regulation of cell migration 24.0000 6 no
GO:0040017 positive regulation of locomotion 24.0000 4 no
GO:0007268 chemical synaptic transmission 20.0000 7 yes
GO:0098916 anterograde trans-synaptic signaling 20.0000 6 yes
GO:1901890 positive regulation of cell junction assembly 20.0000 6 yes
GO:0048812 neuron projection morphogenesis 16.0000 5 yes
GO:0051963 regulation of synapse assembly 16.0000 6 yes
GO:0120039 plasma membrane bounded cell projection morphogenesis 16.0000 4 yes
GO:0051965 positive regulation of synapse assembly 12.0000 6 yes
GO:0099174 regulation of presynapse organization 8.0000 6 yes
GO:1905606 regulation of presynapse assembly 8.0000 7 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NTRK2_HUMAN [view entry] [view interactions] Low throughput yes yes
RB11A_HUMAN [view entry] [view interactions] Low throughput yes yes
LRFN4_HUMAN [view entry] [view interactions] High throughput yes yes
SACA1_HUMAN [view interactions] High throughput no no
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
CFTR_HUMAN [view interactions] High throughput no no
KCNK3_HUMAN [view interactions] High throughput no no
BOLA2_HUMAN [view interactions] High throughput no yes
CLCKA_HUMAN [view interactions] High throughput no no
S39A4_HUMAN [view interactions] High throughput no no
PSG1_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
STAT1_HUMAN [view entry] [view interactions] High throughput yes no
TS1R2_HUMAN [view interactions] High throughput no no
I22R1_HUMAN [view interactions] High throughput no no
TECT2_HUMAN [view interactions] High throughput no yes
AT1B1_HUMAN [view entry] [view interactions] High throughput yes no
LRC33_HUMAN [view interactions] High throughput no yes
SNX27_HUMAN [view entry] [view interactions] High throughput yes no
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RHOQ_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOC_HUMAN [view interactions] High throughput no no
RHOD_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
RHOU_HUMAN [view interactions] High throughput no no
RHOV_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
RND1_HUMAN [view interactions] High throughput no no
RND2_HUMAN [view interactions] High throughput no no
RND3_HUMAN [view interactions] High throughput no no
PSA5_HUMAN [view interactions] High throughput no yes
PLD3_HUMAN [view entry] [view interactions] High throughput yes yes
OTU7A_HUMAN [view interactions] High throughput no no
HAPR1_HUMAN [view interactions] High throughput no yes
RHDF2_HUMAN [view interactions] High throughput no yes
ATG9A_HUMAN [view interactions] High throughput no yes
DTX2_HUMAN [view interactions] High throughput no yes
ARL4C_HUMAN [view interactions] High throughput no yes
ARL14_HUMAN [view interactions] High throughput no no
BRSK2_HUMAN [view interactions] High throughput no no
CDKL5_HUMAN [view entry] [view interactions] High throughput yes yes
CNTP2_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
GRIA2_HUMAN [view entry] [view interactions] High throughput yes yes
LRC4C_HUMAN [view entry] [view interactions] High throughput yes yes
NRX1A_HUMAN [view entry] [view interactions] High throughput yes no
PTK7_HUMAN [view interactions] High throughput no yes
RICTR_HUMAN [view interactions] High throughput no yes
TGON2_HUMAN [view entry] [view interactions] High throughput yes yes