VATG2_HUMAN
Evidence for PS localization
Functions
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in VATG2_HUMAN |
|---|---|---|---|---|
| GO:0015399 | primary active transmembrane transporter activity | 55.0000 | 4 | yes |
| GO:0008324 | cation transmembrane transporter activity | 50.0000 | 4 | no |
| GO:0015078 | proton transmembrane transporter activity | 50.0000 | 5 | no |
| GO:0022890 | inorganic cation transmembrane transporter activity | 50.0000 | 4 | no |
| GO:0009678 | pyrophosphate hydrolysis-driven proton transmembrane transporter activity | 45.0000 | 5 | no |
| GO:0022853 | active ion transmembrane transporter activity | 45.0000 | 4 | no |
| GO:0044769 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism | 45.0000 | 4 | no |
| GO:0046961 | proton-transporting ATPase activity, rotational mechanism | 45.0000 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in VATG2_HUMAN |
|---|---|---|---|---|
| GO:0031323 | regulation of cellular metabolic process | 75.0000 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 70.0000 | 4 | yes |
| GO:0010506 | regulation of autophagy | 65.0000 | 6 | yes |
| GO:0031329 | regulation of cellular catabolic process | 65.0000 | 5 | yes |
| GO:0016241 | regulation of macroautophagy | 60.0000 | 7 | yes |
| GO:0006811 | ion transport | 40.0000 | 4 | yes |
| GO:0006812 | cation transport | 40.0000 | 5 | yes |
| GO:0098655 | cation transmembrane transport | 40.0000 | 4 | yes |
| GO:0098660 | inorganic ion transmembrane transport | 40.0000 | 4 | yes |
| GO:0098662 | inorganic cation transmembrane transport | 40.0000 | 5 | yes |
| GO:1902600 | proton transmembrane transport | 40.0000 | 6 | yes |
| GO:0006873 | cellular ion homeostasis | 30.0000 | 4 | no |
| GO:0030003 | cellular cation homeostasis | 30.0000 | 5 | no |
| GO:0048878 | chemical homeostasis | 30.0000 | 4 | no |
| GO:0050801 | ion homeostasis | 30.0000 | 5 | no |
| GO:0055080 | cation homeostasis | 30.0000 | 6 | no |
| GO:0098771 | inorganic ion homeostasis | 30.0000 | 6 | no |
| GO:0006996 | organelle organization | 25.0000 | 4 | no |
| GO:0008104 | protein localization | 25.0000 | 4 | no |
| GO:0033365 | protein localization to organelle | 25.0000 | 5 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| VATG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VATE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VATA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VPP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VATL_HUMAN | [view interactions] | Low throughput | no | no |
| VATD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VATC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VATB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| VATC2_HUMAN | [view interactions] | High throughput | no | yes |
| VATB1_HUMAN | [view interactions] | High throughput | no | no |
| ACOT6_HUMAN | [view interactions] | High throughput | no | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| VATE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VATO_HUMAN | [view interactions] | High throughput | no | no |
| UBP20_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VPP2_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLHA_HUMAN | [view interactions] | High throughput | no | no |
| DMXL1_HUMAN | [view interactions] | High throughput | no | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DMXL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPB9_HUMAN | [view interactions] | High throughput | no | yes |
| VDR_HUMAN | [view interactions] | High throughput | no | no |
| KAT3_HUMAN | [view interactions] | High throughput | no | yes |
| RBM25_HUMAN | [view interactions] | High throughput | no | yes |
| VATF_HUMAN | [view interactions] | High throughput | no | yes |
| UBA6_HUMAN | [view interactions] | High throughput | no | no |
| POTEF_HUMAN | [view interactions] | High throughput | no | no |
| VAS1_HUMAN | [view interactions] | High throughput | no | yes |
| VA0D2_HUMAN | [view interactions] | High throughput | no | no |
| VATG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NISCH_HUMAN | [view interactions] | High throughput | no | yes |
| VPP3_HUMAN | [view interactions] | High throughput | no | no |
| VATG3_HUMAN | [view interactions] | Computational | no | no |
| ITFG2_HUMAN | [view interactions] | Computational | no | yes |
| NPRL2_HUMAN | [view interactions] | Computational | no | yes |
| SAMTR_HUMAN | [view interactions] | Computational | no | yes |
| VA0D1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| KPTN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FNIP1_HUMAN | [view interactions] | Computational | no | yes |
| VPP4_HUMAN | [view interactions] | Computational | no | no |
| VA0E1_HUMAN | [view interactions] | Computational | no | no |
| WDR59_HUMAN | [view interactions] | Computational | no | yes |
| SEC13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| WDR24_HUMAN | [view interactions] | Computational | no | yes |
| SEH1_HUMAN | [view interactions] | Computational | no | no |
| FNIP2_HUMAN | [view interactions] | Computational | no | yes |
| SESN1_HUMAN | [view interactions] | Computational | no | no |
| SZT2_HUMAN | [view interactions] | Computational | no | yes |
| MIO_HUMAN | [view interactions] | Computational | no | yes |
| SESN2_HUMAN | [view interactions] | Computational | no | no |
| FLCN_HUMAN | [view interactions] | Computational | no | yes |
| CAST1_HUMAN | [view interactions] | Computational | no | yes |
| SH3B4_HUMAN | [view interactions] | Computational | no | yes |
| VATH_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VA0E2_HUMAN | [view interactions] | Computational | no | no |
| CAST2_HUMAN | [view interactions] | Computational | no | no |