Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ACOT8_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

(Microbial infection) May mediate Nef-induced down-regulation of CD4 cell-surface expression (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in ACOT8_HUMAN
GO:0017076 purine nucleotide binding 27.7778 4 no
GO:0032555 purine ribonucleotide binding 27.7778 4 no
GO:0035639 purine ribonucleoside triphosphate binding 22.2222 4 no
GO:0030554 adenyl nucleotide binding 22.2222 5 no
GO:0032559 adenyl ribonucleotide binding 22.2222 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in ACOT8_HUMAN
GO:0019752 carboxylic acid metabolic process 44.4444 5 yes
GO:0032787 monocarboxylic acid metabolic process 44.4444 6 yes
GO:0043436 oxoacid metabolic process 44.4444 4 yes
GO:0006631 fatty acid metabolic process 38.8889 4 yes
GO:0006796 phosphate-containing compound metabolic process 33.3333 4 yes
GO:0031323 regulation of cellular metabolic process 33.3333 4 yes
GO:0048523 negative regulation of cellular process 33.3333 4 yes
GO:0048522 positive regulation of cellular process 33.3333 4 no
GO:0006635 fatty acid beta-oxidation 27.7778 6 yes
GO:0008610 lipid biosynthetic process 27.7778 4 yes
GO:0009062 fatty acid catabolic process 27.7778 5 yes
GO:0009889 regulation of biosynthetic process 27.7778 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 27.7778 5 yes
GO:0016042 lipid catabolic process 27.7778 4 yes
GO:0016054 organic acid catabolic process 27.7778 4 yes
GO:0019395 fatty acid oxidation 27.7778 5 yes
GO:0030258 lipid modification 27.7778 4 yes
GO:0031326 regulation of cellular biosynthetic process 27.7778 5 yes
GO:0034440 lipid oxidation 27.7778 5 yes
GO:0044242 cellular lipid catabolic process 27.7778 4 yes
GO:0046395 carboxylic acid catabolic process 27.7778 5 yes
GO:0051171 regulation of nitrogen compound metabolic process 27.7778 4 yes
GO:0060255 regulation of macromolecule metabolic process 27.7778 4 yes
GO:0072329 monocarboxylic acid catabolic process 27.7778 6 yes
GO:0080090 regulation of primary metabolic process 27.7778 4 yes
GO:0006996 organelle organization 22.2222 4 yes
GO:0008202 steroid metabolic process 22.2222 4 yes
GO:0009890 negative regulation of biosynthetic process 22.2222 5 yes
GO:0009892 negative regulation of metabolic process 22.2222 4 yes
GO:0031324 negative regulation of cellular metabolic process 22.2222 5 yes
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 22.2222 7 yes
GO:0043603 cellular amide metabolic process 22.2222 4 yes
GO:1901362 organic cyclic compound biosynthetic process 22.2222 4 yes
GO:0090407 organophosphate biosynthetic process 22.2222 4 no
GO:0009966 regulation of signal transduction 22.2222 4 no
GO:0010468 regulation of gene expression 22.2222 5 no
GO:0010646 regulation of cell communication 22.2222 4 no
GO:1902531 regulation of intracellular signal transduction 22.2222 5 no
GO:0009893 positive regulation of metabolic process 22.2222 4 no
GO:0001676 long-chain fatty acid metabolic process 16.6667 5 yes
GO:0006163 purine nucleotide metabolic process 16.6667 5 yes
GO:0006637 acyl-CoA metabolic process 16.6667 4 yes
GO:0006753 nucleoside phosphate metabolic process 16.6667 4 yes
GO:0009117 nucleotide metabolic process 16.6667 5 yes
GO:0009150 purine ribonucleotide metabolic process 16.6667 6 yes
GO:0009259 ribonucleotide metabolic process 16.6667 5 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 16.6667 6 yes
GO:0010605 negative regulation of macromolecule metabolic process 16.6667 5 yes
GO:0019693 ribose phosphate metabolic process 16.6667 4 yes
GO:0031327 negative regulation of cellular biosynthetic process 16.6667 6 yes
GO:0033559 unsaturated fatty acid metabolic process 16.6667 5 yes
GO:0033865 nucleoside bisphosphate metabolic process 16.6667 5 yes
GO:0033875 ribonucleoside bisphosphate metabolic process 16.6667 6 yes
GO:0034032 purine nucleoside bisphosphate metabolic process 16.6667 5 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 16.6667 5 yes
GO:0051246 regulation of protein metabolic process 16.6667 5 yes
GO:0072521 purine-containing compound metabolic process 16.6667 4 yes
GO:0008206 bile acid metabolic process 11.1111 4 yes
GO:0016053 organic acid biosynthetic process 11.1111 4 yes
GO:0036109 alpha-linolenic acid metabolic process 11.1111 4 yes
GO:0046394 carboxylic acid biosynthetic process 11.1111 5 yes
GO:0051248 negative regulation of protein metabolic process 11.1111 6 yes
GO:0072330 monocarboxylic acid biosynthetic process 11.1111 6 yes
GO:2000112 regulation of cellular macromolecule biosynthetic process 11.1111 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NEDD1_HUMAN [view interactions] High throughput no yes
KLH23_HUMAN [view interactions] High throughput no no
IGHA1_HUMAN [view entry] [view interactions] High throughput yes yes
PTN3_HUMAN [view interactions] High throughput no yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
MK04_HUMAN [view interactions] High throughput no no
MAST1_HUMAN [view interactions] High throughput no yes
HSC20_HUMAN [view interactions] High throughput no yes
PEX5_HUMAN [view interactions] High throughput no yes
REL_HUMAN [view interactions] High throughput no yes
P4HA3_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
ESR1_HUMAN [view interactions] High throughput no no
CATA_HUMAN [view entry] [view interactions] High throughput yes no
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
PRD16_HUMAN [view interactions] High throughput no no
ISG15_HUMAN [view interactions] High throughput no no
RING2_HUMAN [view interactions] High throughput no yes
PML_HUMAN [view interactions] High throughput no yes
MTMRE_HUMAN [view entry] [view interactions] High throughput yes yes
TP4A1_HUMAN [view interactions] High throughput no no
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA4_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
BRD1_HUMAN [view interactions] High throughput no yes
BRD8_HUMAN [view interactions] High throughput no yes
SP100_HUMAN [view interactions] High throughput no no
TAF1_HUMAN [view interactions] High throughput no yes
TRI66_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
NMRL1_HUMAN [view interactions] High throughput no yes
DX39A_HUMAN [view interactions] High throughput no yes
CDC26_HUMAN [view interactions] High throughput no yes
COA7_HUMAN [view interactions] High throughput no yes
VSTM1_HUMAN [view interactions] High throughput no no
SNX21_HUMAN [view interactions] High throughput no yes
OTUD4_HUMAN [view interactions] High throughput no yes
FBX7_HUMAN [view interactions] High throughput no yes
ACSL1_HUMAN [view interactions] High throughput no no
ACSL6_HUMAN [view entry] [view interactions] High throughput yes yes
ELAV2_HUMAN [view interactions] High throughput no yes
PEX7_HUMAN [view interactions] High throughput no yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
NEDD8_HUMAN [view interactions] High throughput no yes
NMT1_HUMAN [view interactions] High throughput no yes
THIK_HUMAN [view entry] [view interactions] High throughput yes yes
CACP_HUMAN [view entry] [view interactions] High throughput yes yes
HACL1_HUMAN [view interactions] High throughput no no
PTGR3_HUMAN [view interactions] High throughput no yes
RBM47_HUMAN [view interactions] High throughput no yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
ADAS_HUMAN [view interactions] High throughput no yes
AMPN_HUMAN [view interactions] High throughput no no
TM11B_HUMAN [view interactions] High throughput no no
SCP2_HUMAN [view interactions] Computational no no
DCMC_HUMAN [view interactions] Computational no no
PEX10_HUMAN [view interactions] Computational no yes
SPYA_HUMAN [view interactions] Computational no no
GSTK1_HUMAN [view entry] [view interactions] Computational yes yes
IDE_HUMAN [view interactions] Computational no yes
PEX13_HUMAN [view interactions] Computational no yes
BAAT_HUMAN [view interactions] Computational no no
ECI2_HUMAN [view entry] [view interactions] Computational yes yes
ACOT2_HUMAN [view interactions] Computational no yes
SOX_HUMAN [view interactions] Computational no no
HYES_HUMAN [view interactions] Computational no no
OXDA_HUMAN [view interactions] Computational no no
OCTC_HUMAN [view interactions] Computational no yes
ECH1_HUMAN [view interactions] Computational no yes
OXDD_HUMAN [view interactions] Computational no yes
ACOT4_HUMAN [view interactions] Computational no yes
HAOX1_HUMAN [view interactions] Computational no no
ACOX2_HUMAN [view interactions] Computational no yes
DHRS4_HUMAN [view entry] [view interactions] Computational yes no
TYSD1_HUMAN [view interactions] Computational no yes
NOS2_HUMAN [view interactions] Computational no yes
AMACR_HUMAN [view interactions] Computational no yes
PAOX_HUMAN [view interactions] Computational no no
LONP2_HUMAN [view interactions] Computational no yes
NUD19_HUMAN [view interactions] Computational no no
ACOX3_HUMAN [view interactions] Computational no yes
HAOX2_HUMAN [view interactions] Computational no no
ACOT1_HUMAN [view interactions] Computational no yes
ECHP_HUMAN [view interactions] Computational no no
NUDT7_HUMAN [view interactions] Computational no yes
DECR2_HUMAN [view entry] [view interactions] Computational yes no
S27A2_HUMAN [view interactions] Computational no no
IDHC_HUMAN [view interactions] Computational no no
MPV17_HUMAN [view interactions] Computational no no
S27A5_HUMAN [view interactions] Computational no no
ACOX1_HUMAN [view interactions] Computational no yes
PECR_HUMAN [view interactions] Computational no yes
HMGCL_HUMAN [view interactions] Computational no yes
GNPAT_HUMAN [view entry] [view interactions] Computational yes no