CRTC1_HUMAN
Evidence for PS localization
Functions
(Microbial infection) Plays a role of coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CRTC1_HUMAN |
|---|---|---|---|---|
| GO:0045296 | cadherin binding | 33.3333 | 4 | no |
| GO:0003723 | RNA binding | 33.3333 | 4 | no |
| GO:0045309 | protein phosphorylated amino acid binding | 33.3333 | 4 | no |
| GO:0140297 | DNA-binding transcription factor binding | 26.6667 | 4 | yes |
| GO:0019900 | kinase binding | 26.6667 | 4 | no |
| GO:0019901 | protein kinase binding | 26.6667 | 5 | no |
| GO:0019902 | phosphatase binding | 26.6667 | 4 | no |
| GO:0050815 | phosphoserine residue binding | 26.6667 | 5 | no |
| GO:0008140 | cAMP response element binding protein binding | 13.3333 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CRTC1_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 93.3333 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 93.3333 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 86.6667 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 66.6667 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 66.6667 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 66.6667 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 66.6667 | 5 | yes |
| GO:0048522 | positive regulation of cellular process | 66.6667 | 4 | yes |
| GO:0010468 | regulation of gene expression | 60.0000 | 6 | yes |
| GO:0051252 | regulation of RNA metabolic process | 60.0000 | 5 | yes |
| GO:0048523 | negative regulation of cellular process | 60.0000 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 53.3333 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 53.3333 | 6 | yes |
| GO:0051246 | regulation of protein metabolic process | 53.3333 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 46.6667 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 46.6667 | 4 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 46.6667 | 6 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 46.6667 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 46.6667 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 46.6667 | 6 | yes |
| GO:0010646 | regulation of cell communication | 46.6667 | 4 | no |
| GO:0008104 | protein localization | 46.6667 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 46.6667 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 46.6667 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 46.6667 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 40.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 40.0000 | 4 | no |
| GO:0051049 | regulation of transport | 40.0000 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 40.0000 | 6 | no |
| GO:0031399 | regulation of protein modification process | 40.0000 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 40.0000 | 5 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 33.3333 | 8 | yes |
| GO:0022607 | cellular component assembly | 33.3333 | 4 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 33.3333 | 5 | yes |
| GO:0032101 | regulation of response to external stimulus | 33.3333 | 4 | no |
| GO:0036211 | protein modification process | 33.3333 | 4 | no |
| GO:0043412 | macromolecule modification | 33.3333 | 4 | no |
| GO:0050776 | regulation of immune response | 33.3333 | 4 | no |
| GO:0080134 | regulation of response to stress | 33.3333 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 33.3333 | 5 | no |
| GO:0060341 | regulation of cellular localization | 33.3333 | 4 | no |
| GO:0043933 | protein-containing complex organization | 26.6667 | 4 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 26.6667 | 8 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 26.6667 | 6 | yes |
| GO:0065003 | protein-containing complex assembly | 26.6667 | 5 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 26.6667 | 7 | yes |
| GO:0006996 | organelle organization | 26.6667 | 4 | no |
| GO:0002684 | positive regulation of immune system process | 26.6667 | 4 | no |
| GO:0002831 | regulation of response to biotic stimulus | 26.6667 | 4 | no |
| GO:0031347 | regulation of defense response | 26.6667 | 5 | no |
| GO:0032103 | positive regulation of response to external stimulus | 26.6667 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 26.6667 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.6667 | 4 | no |
| GO:0045088 | regulation of innate immune response | 26.6667 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 26.6667 | 4 | no |
| GO:0050778 | positive regulation of immune response | 26.6667 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 26.6667 | 4 | no |
| GO:0006468 | protein phosphorylation | 26.6667 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 26.6667 | 4 | no |
| GO:0016310 | phosphorylation | 26.6667 | 5 | no |
| GO:0051726 | regulation of cell cycle | 26.6667 | 4 | no |
| GO:0006605 | protein targeting | 26.6667 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 26.6667 | 5 | no |
| GO:0010563 | negative regulation of phosphorus metabolic process | 26.6667 | 6 | no |
| GO:0010648 | negative regulation of cell communication | 26.6667 | 5 | no |
| GO:0023057 | negative regulation of signaling | 26.6667 | 4 | no |
| GO:0031400 | negative regulation of protein modification process | 26.6667 | 7 | no |
| GO:0045936 | negative regulation of phosphate metabolic process | 26.6667 | 7 | no |
| GO:0048585 | negative regulation of response to stimulus | 26.6667 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 26.6667 | 6 | no |
| GO:0032386 | regulation of intracellular transport | 26.6667 | 5 | no |
| GO:0032880 | regulation of protein localization | 26.6667 | 5 | no |
| GO:0141124 | intracellular signaling cassette | 26.6667 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 26.6667 | 7 | no |
| GO:0009890 | negative regulation of biosynthetic process | 26.6667 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 26.6667 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 26.6667 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 26.6667 | 7 | no |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | 20.0000 | 9 | yes |
| GO:0050890 | cognition | 20.0000 | 4 | yes |
| GO:0051259 | protein complex oligomerization | 20.0000 | 6 | yes |
| GO:0051260 | protein homooligomerization | 20.0000 | 7 | yes |
| GO:0051262 | protein tetramerization | 20.0000 | 7 | yes |
| GO:0051289 | protein homotetramerization | 20.0000 | 8 | yes |
| GO:0007613 | memory | 13.3333 | 4 | yes |
| GO:0009416 | response to light stimulus | 13.3333 | 4 | yes |
| GO:0009648 | photoperiodism | 13.3333 | 5 | yes |
| GO:0032793 | positive regulation of CREB transcription factor activity | 13.3333 | 5 | yes |
| GO:0043153 | entrainment of circadian clock by photoperiod | 13.3333 | 4 | yes |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity | 13.3333 | 4 | yes |
| GO:1902631 | negative regulation of membrane hyperpolarization | 13.3333 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MEIS1_HUMAN | [view interactions] | Low throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| M3K1_HUMAN | [view interactions] | Low throughput | no | yes |
| CBP_HUMAN | [view interactions] | Low throughput | no | yes |
| EP300_HUMAN | [view interactions] | Low throughput | no | yes |
| TFG_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TBK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CRTC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CREB1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| KI13B_HUMAN | [view interactions] | High throughput | no | yes |
| CBY1_HUMAN | [view interactions] | High throughput | no | no |
| KCTD3_HUMAN | [view interactions] | High throughput | no | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHRM2_HUMAN | [view interactions] | High throughput | no | yes |
| PDZ11_HUMAN | [view interactions] | High throughput | no | yes |
| REEP1_HUMAN | [view interactions] | High throughput | no | yes |
| WAC_HUMAN | [view interactions] | High throughput | no | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| VASP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| PF21A_HUMAN | [view interactions] | High throughput | no | yes |