ACHA6_HUMAN
Evidence for PS localization
Functions
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
No data found.
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ACHA6_HUMAN |
|---|---|---|---|---|
| GO:0010646 | regulation of cell communication | 100.0000 | 4 | yes |
| GO:0007268 | chemical synaptic transmission | 66.6667 | 7 | yes |
| GO:0007271 | synaptic transmission, cholinergic | 66.6667 | 8 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 66.6667 | 5 | yes |
| GO:0051049 | regulation of transport | 66.6667 | 4 | yes |
| GO:0098916 | anterograde trans-synaptic signaling | 66.6667 | 6 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 66.6667 | 4 | yes |
| GO:0099536 | synaptic signaling | 66.6667 | 4 | yes |
| GO:0099537 | trans-synaptic signaling | 66.6667 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 66.6667 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LYPD6_HUMAN | [view interactions] | High throughput | no | no |
| LYNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CANB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |