Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

GP179_HUMAN

GO
G2C
SynGO
SynaptomeDB

Orphan receptor involved in vision (PubMed, PubMed). Required for signal transduction through retinal depolarizing bipolar cells (PubMed). Acts as an atypical G-protein coupled receptor that recruits and regulates the R7 group RGS-GNB5 complexes instead of activating G proteins: promotes the GTPase activator activity of R7 RGS proteins, increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form . Associates with components of metabotropic signaling cascade in retina ON-bipolar neurons, such as TRPM1 and GRM6: may control the ability of the GRM6 cascade to gate TRPM1 . [View more on UniProt]

02004006008001,0001,2001,4001,6001,8002,0002,200
Phase separation
ELM
Phosphorylation
PFAM
Coiled coil
Anchor
Disordered
Interacting regions
Sequence
LOADING 91%

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02004006008001,0001,2001,4001,6001,8002,0002,200
GP179_HUMAN
LOADING 67%
Download full PS network for entry.
02004006008001,0001,2001,4001,6001,8002,0002,200
Interacting regions
Canonical [GP179_HUMAN]
Isoform [A0A087X0K8] alignment
LOADING 80%

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Biological process

Disease

No data found.

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