LRFN5_HUMAN
Evidence for PS localization
Functions
Cell adhesion molecule that mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
No data found.
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in LRFN5_HUMAN |
|---|---|---|---|---|
| GO:0044087 | regulation of cellular component biogenesis | 100.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 100.0000 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 100.0000 | 4 | yes |
| GO:0050807 | regulation of synapse organization | 100.0000 | 5 | yes |
| GO:0051128 | regulation of cellular component organization | 100.0000 | 4 | yes |
| GO:0051963 | regulation of synapse assembly | 100.0000 | 6 | yes |
| GO:0098742 | cell-cell adhesion via plasma-membrane adhesion molecules | 100.0000 | 4 | yes |
| GO:0099560 | synaptic membrane adhesion | 100.0000 | 5 | yes |
| GO:1901888 | regulation of cell junction assembly | 100.0000 | 5 | yes |
| GO:0002683 | negative regulation of immune system process | 66.6667 | 4 | yes |
| GO:0002694 | regulation of leukocyte activation | 66.6667 | 4 | yes |
| GO:0002695 | negative regulation of leukocyte activation | 66.6667 | 5 | yes |
| GO:0031347 | regulation of defense response | 66.6667 | 5 | yes |
| GO:0031348 | negative regulation of defense response | 66.6667 | 5 | yes |
| GO:0032101 | regulation of response to external stimulus | 66.6667 | 4 | yes |
| GO:0032102 | negative regulation of response to external stimulus | 66.6667 | 5 | yes |
| GO:0043030 | regulation of macrophage activation | 66.6667 | 5 | yes |
| GO:0043031 | negative regulation of macrophage activation | 66.6667 | 6 | yes |
| GO:0050727 | regulation of inflammatory response | 66.6667 | 5 | yes |
| GO:0050728 | negative regulation of inflammatory response | 66.6667 | 6 | yes |
| GO:0050865 | regulation of cell activation | 66.6667 | 4 | yes |
| GO:0050866 | negative regulation of cell activation | 66.6667 | 5 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 66.6667 | 4 | yes |
| GO:0080134 | regulation of response to stress | 66.6667 | 4 | yes |
| GO:0099174 | regulation of presynapse organization | 66.6667 | 6 | yes |
| GO:1905606 | regulation of presynapse assembly | 66.6667 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LRFN5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PTPRD_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TLK2_HUMAN | [view interactions] | High throughput | no | no |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |