PADI2_HUMAN
Evidence for PS localization
Functions
Catalyzes the deimination of arginine residues of proteins. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PADI2_HUMAN |
|---|---|---|---|---|
| GO:0140297 | DNA-binding transcription factor binding | 66.6667 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PADI2_HUMAN |
|---|---|---|---|---|
| GO:0002683 | negative regulation of immune system process | 66.6667 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 66.6667 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 66.6667 | 4 | yes |
| GO:0009968 | negative regulation of signal transduction | 66.6667 | 5 | yes |
| GO:0010468 | regulation of gene expression | 66.6667 | 6 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 66.6667 | 5 | yes |
| GO:0010646 | regulation of cell communication | 66.6667 | 4 | yes |
| GO:0010648 | negative regulation of cell communication | 66.6667 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 66.6667 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 66.6667 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 66.6667 | 5 | yes |
| GO:0032101 | regulation of response to external stimulus | 66.6667 | 4 | yes |
| GO:0032102 | negative regulation of response to external stimulus | 66.6667 | 5 | yes |
| GO:0048523 | negative regulation of cellular process | 66.6667 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 66.6667 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 66.6667 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 66.6667 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTMRE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIF1A_HUMAN | [view interactions] | High throughput | no | yes |
| CSH1_HUMAN | [view interactions] | High throughput | no | no |
| KLK10_HUMAN | [view interactions] | High throughput | no | no |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |