Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PGM2L_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Glucose 1,6-bisphosphate synthase using 1,3-bisphosphoglycerate as a phosphate donor and a series of 1-phosphate sugars as acceptors, including glucose 1-phosphate, mannose 1-phosphate, ribose 1-phosphate and deoxyribose 1-phosphate. 5 or 6-phosphosugars are bad substrates, with the exception of glucose 6-phosphate. Also synthesizes ribose 1,5-bisphosphate. Has only low phosphopentomutase and phosphoglucomutase activities. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PGM2L_HUMAN
GO:0016758 hexosyltransferase activity 37.5000 4 no
GO:0046872 metal ion binding 25.0000 4 yes
GO:0004645 1,4-alpha-oligoglucan phosphorylase activity 25.0000 5 no
GO:0008184 glycogen phosphorylase activity 25.0000 6 no
GO:0030170 pyridoxal phosphate binding 25.0000 4 no
GO:0102250 linear malto-oligosaccharide phosphorylase activity 25.0000 5 no
GO:0102499 SHG alpha-glucan phosphorylase activity 25.0000 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in PGM2L_HUMAN
GO:0016052 carbohydrate catabolic process 50.0000 4 no
GO:0044275 cellular carbohydrate catabolic process 50.0000 4 no
GO:0005976 polysaccharide metabolic process 50.0000 4 no
GO:0005977 glycogen metabolic process 50.0000 6 no
GO:0006073 cellular glucan metabolic process 50.0000 5 no
GO:0006112 energy reserve metabolic process 50.0000 5 no
GO:0015980 energy derivation by oxidation of organic compounds 50.0000 4 no
GO:0044042 glucan metabolic process 50.0000 5 no
GO:0044264 cellular polysaccharide metabolic process 50.0000 4 no
GO:0016051 carbohydrate biosynthetic process 37.5000 4 no
GO:0000272 polysaccharide catabolic process 37.5000 5 no
GO:0005980 glycogen catabolic process 37.5000 6 no
GO:0009057 macromolecule catabolic process 37.5000 4 no
GO:0009251 glucan catabolic process 37.5000 6 no
GO:0044247 cellular polysaccharide catabolic process 37.5000 5 no
GO:0006006 glucose metabolic process 25.0000 5 yes
GO:0019318 hexose metabolic process 25.0000 4 yes
GO:0006996 organelle organization 25.0000 4 no
GO:0022603 regulation of anatomical structure morphogenesis 25.0000 4 no
GO:0030030 cell projection organization 25.0000 4 no
GO:0031344 regulation of cell projection organization 25.0000 5 no
GO:0031346 positive regulation of cell projection organization 25.0000 6 no
GO:0032880 regulation of protein localization 25.0000 5 no
GO:0032990 cell part morphogenesis 25.0000 4 no
GO:0043085 positive regulation of catalytic activity 25.0000 4 no
GO:0048522 positive regulation of cellular process 25.0000 4 no
GO:0048584 positive regulation of response to stimulus 25.0000 4 no
GO:0048812 neuron projection morphogenesis 25.0000 7 no
GO:0048858 cell projection morphogenesis 25.0000 5 no
GO:0051049 regulation of transport 25.0000 4 no
GO:0051094 positive regulation of developmental process 25.0000 4 no
GO:0051128 regulation of cellular component organization 25.0000 4 no
GO:0051130 positive regulation of cellular component organization 25.0000 5 no
GO:0060341 regulation of cellular localization 25.0000 4 no
GO:0120039 plasma membrane bounded cell projection morphogenesis 25.0000 6 no
GO:0006796 phosphate-containing compound metabolic process 25.0000 4 no
GO:0000271 polysaccharide biosynthetic process 25.0000 5 no
GO:0005978 glycogen biosynthetic process 25.0000 7 no
GO:0009059 macromolecule biosynthetic process 25.0000 4 no
GO:0009250 glucan biosynthetic process 25.0000 6 no
GO:0033692 cellular polysaccharide biosynthetic process 25.0000 5 no
GO:0034637 cellular carbohydrate biosynthetic process 25.0000 4 no
GO:0034645 cellular macromolecule biosynthetic process 25.0000 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
SKA3_HUMAN [view interactions] High throughput no no
KIF22_HUMAN [view interactions] High throughput no no
NDEL1_HUMAN [view entry] [view interactions] High throughput yes yes
OAZ1_HUMAN [view interactions] High throughput no yes
APBB1_HUMAN [view interactions] High throughput no yes
NPSR1_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
E2AK4_HUMAN [view interactions] High throughput no yes
ARFP1_HUMAN [view interactions] High throughput no no
CH10_HUMAN [view interactions] High throughput no yes
TPIS_HUMAN [view entry] [view interactions] High throughput yes yes
PIPNB_HUMAN [view interactions] High throughput no no
PYGB_HUMAN [view entry] [view interactions] Computational yes no
UGPA_HUMAN [view entry] [view interactions] Computational yes no
PYGM_HUMAN [view entry] [view interactions] Computational yes no
UPP1_HUMAN [view interactions] Computational no no
ENPP3_HUMAN [view interactions] Computational no no
PYGL_HUMAN [view interactions] Computational no yes
HOT_HUMAN [view interactions] Computational no no
PGM2_HUMAN [view interactions] Computational no no
GDE_HUMAN [view entry] [view interactions] Computational yes no