Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CBLN1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

The cerebellin peptide exerts neuromodulatory functions. Directly stimulates norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

No data found.

Biological process

Term Name % Distance from top the of the tree Annotated in CBLN1_HUMAN
GO:0007268 chemical synaptic transmission 100.0000 7 yes
GO:0007416 synapse assembly 100.0000 6 yes
GO:0008104 protein localization 100.0000 4 yes
GO:0010646 regulation of cell communication 100.0000 4 yes
GO:0022607 cellular component assembly 100.0000 4 yes
GO:0034329 cell junction assembly 100.0000 5 yes
GO:0034330 cell junction organization 100.0000 4 yes
GO:0044087 regulation of cellular component biogenesis 100.0000 4 yes
GO:0044089 positive regulation of cellular component biogenesis 100.0000 5 yes
GO:0048522 positive regulation of cellular process 100.0000 4 yes
GO:0050804 modulation of chemical synaptic transmission 100.0000 5 yes
GO:0050807 regulation of synapse organization 100.0000 5 yes
GO:0050808 synapse organization 100.0000 5 yes
GO:0051094 positive regulation of developmental process 100.0000 4 yes
GO:0051128 regulation of cellular component organization 100.0000 4 yes
GO:0051130 positive regulation of cellular component organization 100.0000 5 yes
GO:0051240 positive regulation of multicellular organismal process 100.0000 4 yes
GO:0051960 regulation of nervous system development 100.0000 5 yes
GO:0051962 positive regulation of nervous system development 100.0000 5 yes
GO:0051963 regulation of synapse assembly 100.0000 6 yes
GO:0051965 positive regulation of synapse assembly 100.0000 6 yes
GO:0098916 anterograde trans-synaptic signaling 100.0000 6 yes
GO:0099177 regulation of trans-synaptic signaling 100.0000 4 yes
GO:0099536 synaptic signaling 100.0000 4 yes
GO:0099537 trans-synaptic signaling 100.0000 5 yes
GO:1901888 regulation of cell junction assembly 100.0000 5 yes
GO:1901890 positive regulation of cell junction assembly 100.0000 6 yes
GO:2000026 regulation of multicellular organismal development 100.0000 4 yes
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 75.0000 5 yes
GO:0009966 regulation of signal transduction 75.0000 4 yes
GO:0021533 cell differentiation in hindbrain 75.0000 4 yes
GO:0021707 cerebellar granule cell differentiation 75.0000 5 yes
GO:0021953 central nervous system neuron differentiation 75.0000 5 yes
GO:0030182 neuron differentiation 75.0000 4 yes
GO:0031644 regulation of nervous system process 75.0000 5 yes
GO:0033043 regulation of organelle organization 75.0000 5 yes
GO:0044057 regulation of system process 75.0000 4 yes
GO:0046903 secretion 75.0000 4 yes
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 75.0000 4 yes
GO:0098815 modulation of excitatory postsynaptic potential 75.0000 4 yes
GO:0099150 regulation of postsynaptic specialization assembly 75.0000 6 yes
GO:0099151 regulation of postsynaptic density assembly 75.0000 7 yes
GO:0099174 regulation of presynapse organization 75.0000 6 yes
GO:0099175 regulation of postsynapse organization 75.0000 6 yes
GO:1900452 regulation of long-term synaptic depression 75.0000 4 yes
GO:1900454 positive regulation of long-term synaptic depression 75.0000 4 yes
GO:1902115 regulation of organelle assembly 75.0000 5 yes
GO:1904889 regulation of excitatory synapse assembly 75.0000 7 yes
GO:1905606 regulation of presynapse assembly 75.0000 7 yes
GO:1905874 regulation of postsynaptic density organization 75.0000 6 yes
GO:1905962 glutamatergic neuron differentiation 75.0000 5 yes
GO:0007399 nervous system development 50.0000 4 yes
GO:0009306 protein secretion 50.0000 4 yes
GO:0015031 protein transport 50.0000 4 yes
GO:0034331 cell junction maintenance 50.0000 5 yes
GO:0035592 establishment of protein localization to extracellular region 50.0000 4 yes
GO:0043954 cellular component maintenance 50.0000 4 yes
GO:0048523 negative regulation of cellular process 50.0000 4 yes
GO:0051093 negative regulation of developmental process 50.0000 4 yes
GO:0051129 negative regulation of cellular component organization 50.0000 5 yes
GO:0051241 negative regulation of multicellular organismal process 50.0000 4 yes
GO:0051961 negative regulation of nervous system development 50.0000 5 yes
GO:0051964 negative regulation of synapse assembly 50.0000 6 yes
GO:0071692 protein localization to extracellular region 50.0000 5 yes
GO:0071702 organic substance transport 50.0000 4 yes
GO:0071705 nitrogen compound transport 50.0000 4 yes
GO:0090394 negative regulation of excitatory postsynaptic potential 50.0000 4 yes
GO:0099558 maintenance of synapse structure 50.0000 6 yes
GO:1901889 negative regulation of cell junction assembly 50.0000 6 yes
GO:1905702 regulation of inhibitory synapse assembly 50.0000 7 yes
GO:1905703 negative regulation of inhibitory synapse assembly 50.0000 7 yes
GO:1905809 negative regulation of synapse organization 50.0000 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
GRID2_HUMAN [view entry] [view interactions] Low throughput yes no
NRX1A_HUMAN [view entry] [view interactions] Low throughput yes no
CBLN1_HUMAN [view entry] [view interactions] Low throughput yes no
FACD2_HUMAN [view interactions] High throughput no no
UBE2H_HUMAN [view interactions] High throughput no yes
CBLN3_HUMAN [view interactions] High throughput no no