CXB6_HUMAN
Evidence for PS localization
Functions
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CXB6_HUMAN |
|---|---|---|---|---|
| GO:0004930 | G protein-coupled receptor activity | 40.0000 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CXB6_HUMAN |
|---|---|---|---|---|
| GO:0048523 | negative regulation of cellular process | 80.0000 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 60.0000 | 4 | no |
| GO:0034330 | cell junction organization | 60.0000 | 4 | yes |
| GO:0045216 | cell-cell junction organization | 60.0000 | 5 | yes |
| GO:0031323 | regulation of cellular metabolic process | 60.0000 | 4 | no |
| GO:0033043 | regulation of organelle organization | 60.0000 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 60.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 60.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 60.0000 | 4 | no |
| GO:0001885 | endothelial cell development | 40.0000 | 5 | no |
| GO:0002064 | epithelial cell development | 40.0000 | 4 | no |
| GO:0003018 | vascular process in circulatory system | 40.0000 | 4 | no |
| GO:0030334 | regulation of cell migration | 40.0000 | 5 | no |
| GO:0030335 | positive regulation of cell migration | 40.0000 | 6 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 40.0000 | 5 | no |
| GO:0032970 | regulation of actin filament-based process | 40.0000 | 4 | no |
| GO:0034331 | cell junction maintenance | 40.0000 | 5 | no |
| GO:0040017 | positive regulation of locomotion | 40.0000 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 40.0000 | 4 | no |
| GO:0043954 | cellular component maintenance | 40.0000 | 4 | no |
| GO:0045217 | cell-cell junction maintenance | 40.0000 | 6 | no |
| GO:0048522 | positive regulation of cellular process | 40.0000 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 40.0000 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 40.0000 | 6 | no |
| GO:0061028 | establishment of endothelial barrier | 40.0000 | 6 | no |
| GO:0110053 | regulation of actin filament organization | 40.0000 | 6 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 40.0000 | 5 | no |
| GO:2000145 | regulation of cell motility | 40.0000 | 4 | no |
| GO:2000147 | positive regulation of cell motility | 40.0000 | 5 | no |
| GO:0001894 | tissue homeostasis | 40.0000 | 4 | yes |
| GO:0007043 | cell-cell junction assembly | 40.0000 | 6 | yes |
| GO:0022607 | cellular component assembly | 40.0000 | 4 | yes |
| GO:0034329 | cell junction assembly | 40.0000 | 5 | yes |
| GO:0035633 | maintenance of blood-brain barrier | 40.0000 | 5 | yes |
| GO:0042127 | regulation of cell population proliferation | 40.0000 | 4 | yes |
| GO:0006996 | organelle organization | 40.0000 | 4 | no |
| GO:0008104 | protein localization | 40.0000 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 40.0000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 40.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.0000 | 5 | no |
| GO:0010639 | negative regulation of organelle organization | 40.0000 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 40.0000 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 40.0000 | 5 | no |
| GO:0071702 | organic substance transport | 40.0000 | 4 | no |
| GO:0071705 | nitrogen compound transport | 40.0000 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CNST_HUMAN | [view interactions] | Low throughput | no | yes |
| ZO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CXB3_HUMAN | [view interactions] | Low throughput | no | no |
| NKG2A_HUMAN | [view interactions] | High throughput | no | no |
| LHPL5_HUMAN | [view interactions] | High throughput | no | no |
| TM218_HUMAN | [view interactions] | High throughput | no | no |
| SOAT_HUMAN | [view interactions] | High throughput | no | no |
| M4A13_HUMAN | [view interactions] | High throughput | no | no |
| EBP_HUMAN | [view interactions] | High throughput | no | no |
| SC22B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GPR61_HUMAN | [view interactions] | High throughput | no | yes |
| SC22A_HUMAN | [view interactions] | High throughput | no | no |
| TMM60_HUMAN | [view interactions] | High throughput | no | no |
| PAR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACM5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SMAD1_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD5_HUMAN | [view interactions] | High throughput | no | no |
| SMAD9_HUMAN | [view interactions] | High throughput | no | yes |
| VMA21_HUMAN | [view interactions] | High throughput | no | no |
| FUT8_HUMAN | [view interactions] | High throughput | no | yes |
| SPPL3_HUMAN | [view interactions] | High throughput | no | no |