Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ERG24_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in ERG24_HUMAN
GO:0000166 nucleotide binding 28.5714 4 yes
GO:0017076 purine nucleotide binding 28.5714 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ERG24_HUMAN
GO:0060255 regulation of macromolecule metabolic process 71.4286 4 no
GO:0080090 regulation of primary metabolic process 57.1429 4 no
GO:0031323 regulation of cellular metabolic process 57.1429 4 no
GO:0006996 organelle organization 42.8571 4 no
GO:0008104 protein localization 42.8571 4 no
GO:0009893 positive regulation of metabolic process 42.8571 4 no
GO:0009966 regulation of signal transduction 42.8571 4 no
GO:0010604 positive regulation of macromolecule metabolic process 42.8571 5 no
GO:0010646 regulation of cell communication 42.8571 4 no
GO:0022603 regulation of anatomical structure morphogenesis 42.8571 4 no
GO:0022607 cellular component assembly 42.8571 4 no
GO:0030030 cell projection organization 42.8571 4 no
GO:0031344 regulation of cell projection organization 42.8571 5 no
GO:0048522 positive regulation of cellular process 42.8571 4 no
GO:0051128 regulation of cellular component organization 42.8571 4 no
GO:0051246 regulation of protein metabolic process 42.8571 5 no
GO:0051247 positive regulation of protein metabolic process 42.8571 6 no
GO:0120036 plasma membrane bounded cell projection organization 42.8571 5 no
GO:0031326 regulation of cellular biosynthetic process 28.5714 5 no
GO:0001932 regulation of protein phosphorylation 28.5714 7 no
GO:0001934 positive regulation of protein phosphorylation 28.5714 8 no
GO:0007268 chemical synaptic transmission 28.5714 7 no
GO:0009967 positive regulation of signal transduction 28.5714 5 no
GO:0010562 positive regulation of phosphorus metabolic process 28.5714 6 no
GO:0010647 positive regulation of cell communication 28.5714 5 no
GO:0019220 regulation of phosphate metabolic process 28.5714 6 no
GO:0023056 positive regulation of signaling 28.5714 4 no
GO:0031325 positive regulation of cellular metabolic process 28.5714 5 no
GO:0031346 positive regulation of cell projection organization 28.5714 6 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0031401 positive regulation of protein modification process 28.5714 7 no
GO:0033365 protein localization to organelle 28.5714 5 no
GO:0042325 regulation of phosphorylation 28.5714 7 no
GO:0042327 positive regulation of phosphorylation 28.5714 8 no
GO:0045937 positive regulation of phosphate metabolic process 28.5714 7 no
GO:0048523 negative regulation of cellular process 28.5714 4 no
GO:0048584 positive regulation of response to stimulus 28.5714 4 no
GO:0050804 modulation of chemical synaptic transmission 28.5714 5 no
GO:0051094 positive regulation of developmental process 28.5714 4 no
GO:0051130 positive regulation of cellular component organization 28.5714 5 no
GO:0051174 regulation of phosphorus metabolic process 28.5714 5 no
GO:0072657 protein localization to membrane 28.5714 4 no
GO:0098916 anterograde trans-synaptic signaling 28.5714 6 no
GO:0099177 regulation of trans-synaptic signaling 28.5714 4 no
GO:0099536 synaptic signaling 28.5714 4 no
GO:0099537 trans-synaptic signaling 28.5714 5 no
GO:1990778 protein localization to cell periphery 28.5714 5 no
GO:0007010 cytoskeleton organization 28.5714 5 no
GO:0010975 regulation of neuron projection development 28.5714 7 no
GO:0030031 cell projection assembly 28.5714 5 no
GO:0050807 regulation of synapse organization 28.5714 5 no
GO:0120031 plasma membrane bounded cell projection assembly 28.5714 6 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 28.5714 6 no
GO:0009889 regulation of biosynthetic process 28.5714 4 no
GO:0010468 regulation of gene expression 28.5714 6 no
GO:0010556 regulation of macromolecule biosynthetic process 28.5714 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
NMRL1_HUMAN [view interactions] High throughput no yes
TSN15_HUMAN [view interactions] High throughput no yes
PLD3_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
RAP2A_HUMAN [view entry] [view interactions] High throughput yes yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
CFTR_HUMAN [view interactions] High throughput no no
CRTP1_HUMAN [view interactions] High throughput no yes
LCE2C_HUMAN [view interactions] High throughput no no
ACM4_HUMAN [view entry] [view interactions] High throughput yes yes
SUZ12_HUMAN [view interactions] High throughput no no
EED_HUMAN [view interactions] High throughput no yes
PRC1_HUMAN [view interactions] High throughput no yes