GBRE_HUMAN
Evidence for PS localization
Functions
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in GBRE_HUMAN |
|---|---|---|---|---|
| GO:0005216 | monoatomic ion channel activity | 50.0000 | 4 | yes |
| GO:0015267 | channel activity | 50.0000 | 4 | yes |
| GO:0022836 | gated channel activity | 50.0000 | 5 | yes |
| GO:0000166 | nucleotide binding | 50.0000 | 4 | no |
| GO:0017076 | purine nucleotide binding | 50.0000 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 50.0000 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 50.0000 | 4 | no |
| GO:0043168 | anion binding | 50.0000 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in GBRE_HUMAN |
|---|---|---|---|---|
| GO:0006811 | monoatomic ion transport | 75.0000 | 4 | yes |
| GO:0006812 | monoatomic cation transport | 50.0000 | 5 | no |
| GO:0006813 | potassium ion transport | 50.0000 | 7 | no |
| GO:0030001 | metal ion transport | 50.0000 | 6 | no |
| GO:0071805 | potassium ion transmembrane transport | 50.0000 | 5 | no |
| GO:0098655 | monoatomic cation transmembrane transport | 50.0000 | 4 | no |
| GO:0098662 | inorganic cation transmembrane transport | 50.0000 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| GPHRB_HUMAN | [view interactions] | High throughput | no | no |
| FZD6_HUMAN | [view interactions] | High throughput | no | yes |
| FADS1_HUMAN | [view interactions] | High throughput | no | yes |
| HLAA_HUMAN | [view interactions] | High throughput | no | no |
| EPHB4_HUMAN | [view interactions] | High throughput | no | yes |
| ERMP1_HUMAN | [view interactions] | High throughput | no | no |
| TTC17_HUMAN | [view interactions] | High throughput | no | yes |
| F241B_HUMAN | [view interactions] | High throughput | no | yes |
| SGPP1_HUMAN | [view interactions] | High throughput | no | no |
| TM39A_HUMAN | [view interactions] | High throughput | no | yes |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| SC11A_HUMAN | [view interactions] | High throughput | no | no |
| LSR_HUMAN | [view interactions] | High throughput | no | yes |
| PIGO_HUMAN | [view interactions] | High throughput | no | no |
| ALG9_HUMAN | [view interactions] | High throughput | no | yes |
| GPAA1_HUMAN | [view interactions] | High throughput | no | yes |
| B3A2_HUMAN | [view interactions] | High throughput | no | yes |
| TMTC3_HUMAN | [view interactions] | High throughput | no | yes |
| CCPG1_HUMAN | [view interactions] | High throughput | no | yes |
| TGO1_HUMAN | [view interactions] | High throughput | no | yes |
| HEM3_HUMAN | [view interactions] | High throughput | no | yes |
| STIM1_HUMAN | [view interactions] | High throughput | no | yes |
| SPCS2_HUMAN | [view interactions] | High throughput | no | yes |
| POMT1_HUMAN | [view interactions] | High throughput | no | no |
| S39A6_HUMAN | [view interactions] | High throughput | no | yes |
| GHITM_HUMAN | [view interactions] | High throughput | no | yes |
| KCNQ5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLCC1_HUMAN | [view interactions] | High throughput | no | yes |
| ASTRA_HUMAN | [view interactions] | High throughput | no | no |
| FZD2_HUMAN | [view interactions] | High throughput | no | no |
| CTR2_HUMAN | [view interactions] | High throughput | no | no |
| GPHRA_HUMAN | [view interactions] | High throughput | no | no |
| BSCL2_HUMAN | [view interactions] | High throughput | no | yes |
| CNNM1_HUMAN | [view interactions] | High throughput | no | yes |
| PIGM_HUMAN | [view interactions] | High throughput | no | no |
| TMED7_HUMAN | [view interactions] | High throughput | no | yes |
| MITOS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNJ8_HUMAN | [view interactions] | High throughput | no | yes |
| GP1BB_HUMAN | [view interactions] | High throughput | no | no |
| S47A1_HUMAN | [view interactions] | High throughput | no | no |
| ENTP4_HUMAN | [view interactions] | High throughput | no | yes |
| EREP3_HUMAN | [view interactions] | High throughput | no | no |
| LMF2_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| PARVA_HUMAN | [view interactions] | High throughput | no | yes |
| TBL2_HUMAN | [view interactions] | High throughput | no | no |
| XRP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| B4GA1_HUMAN | [view interactions] | High throughput | no | yes |
| LRC15_HUMAN | [view interactions] | High throughput | no | no |