Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PCD17_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Potential calcium-dependent cell-adhesion protein. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI004111 LIG_WRC_WIRS_1 LIG 998 1003 -
ELMI004111 LIG_WRC_WIRS_1 LIG 998 1003 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PCD17_HUMAN
GO:0000166 nucleotide binding 66.6667 4 no
GO:0017076 purine nucleotide binding 66.6667 5 no
GO:0032555 purine ribonucleotide binding 66.6667 4 no
GO:0043168 anion binding 66.6667 4 no
GO:0035639 purine ribonucleoside triphosphate binding 60.0000 4 no
GO:0016462 pyrophosphatase activity 53.3333 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 53.3333 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 53.3333 6 no
GO:0003924 GTPase activity 46.6667 7 no
GO:0005525 GTP binding 46.6667 5 no
GO:0019001 guanyl nucleotide binding 46.6667 6 no
GO:0032561 guanyl ribonucleotide binding 46.6667 5 no
GO:0019900 kinase binding 40.0000 4 no
GO:0019901 protein kinase binding 33.3333 5 no
GO:0043169 cation binding 20.0000 4 yes
GO:0046872 metal ion binding 20.0000 5 yes
GO:0005509 calcium ion binding 13.3333 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PCD17_HUMAN
GO:0022607 cellular component assembly 73.3333 4 yes
GO:0048522 positive regulation of cellular process 66.6667 4 no
GO:0048523 negative regulation of cellular process 60.0000 4 yes
GO:0141124 intracellular signaling cassette 60.0000 4 no
GO:0051128 regulation of cellular component organization 60.0000 4 no
GO:0007015 actin filament organization 53.3333 5 no
GO:0007264 small GTPase-mediated signal transduction 53.3333 5 no
GO:0097435 supramolecular fiber organization 53.3333 4 no
GO:0032970 regulation of actin filament-based process 46.6667 4 no
GO:0006996 organelle organization 46.6667 4 no
GO:0031344 regulation of cell projection organization 46.6667 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 46.6667 6 no
GO:0010646 regulation of cell communication 40.0000 4 yes
GO:0007010 cytoskeleton organization 40.0000 5 no
GO:0022603 regulation of anatomical structure morphogenesis 40.0000 4 no
GO:0030155 regulation of cell adhesion 40.0000 4 no
GO:0030334 regulation of cell migration 40.0000 5 no
GO:0032956 regulation of actin cytoskeleton organization 40.0000 5 no
GO:0033043 regulation of organelle organization 40.0000 5 no
GO:0051493 regulation of cytoskeleton organization 40.0000 6 no
GO:2000145 regulation of cell motility 40.0000 4 no
GO:0031323 regulation of cellular metabolic process 40.0000 4 no
GO:0044087 regulation of cellular component biogenesis 40.0000 4 no
GO:0048584 positive regulation of response to stimulus 40.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 40.0000 4 no
GO:0080090 regulation of primary metabolic process 40.0000 4 no
GO:0010810 regulation of cell-substrate adhesion 33.3333 5 no
GO:0016055 Wnt signaling pathway 33.3333 4 no
GO:0030030 cell projection organization 33.3333 4 no
GO:0045785 positive regulation of cell adhesion 33.3333 5 no
GO:0009889 regulation of biosynthetic process 33.3333 4 no
GO:0009893 positive regulation of metabolic process 33.3333 4 no
GO:0010468 regulation of gene expression 33.3333 6 no
GO:0010556 regulation of macromolecule biosynthetic process 33.3333 5 no
GO:0010604 positive regulation of macromolecule metabolic process 33.3333 5 no
GO:0030335 positive regulation of cell migration 33.3333 6 no
GO:0031326 regulation of cellular biosynthetic process 33.3333 5 no
GO:0040017 positive regulation of locomotion 33.3333 4 no
GO:0042127 regulation of cell population proliferation 33.3333 4 no
GO:0044089 positive regulation of cellular component biogenesis 33.3333 5 no
GO:0051130 positive regulation of cellular component organization 33.3333 5 no
GO:2000147 positive regulation of cell motility 33.3333 5 no
GO:0060491 regulation of cell projection assembly 33.3333 5 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 33.3333 6 no
GO:0043085 positive regulation of catalytic activity 26.6667 4 no
GO:0051049 regulation of transport 26.6667 4 no
GO:0002685 regulation of leukocyte migration 26.6667 4 no
GO:0010324 membrane invagination 26.6667 5 no
GO:0016601 Rac protein signal transduction 26.6667 6 no
GO:0030031 cell projection assembly 26.6667 5 no
GO:0031175 neuron projection development 26.6667 6 no
GO:0061024 membrane organization 26.6667 4 no
GO:0099024 plasma membrane invagination 26.6667 6 no
GO:0120036 plasma membrane bounded cell projection organization 26.6667 5 no
GO:0002684 positive regulation of immune system process 26.6667 4 no
GO:0007266 Rho protein signal transduction 26.6667 6 no
GO:0009966 regulation of signal transduction 26.6667 4 no
GO:0009967 positive regulation of signal transduction 26.6667 5 no
GO:0010638 positive regulation of organelle organization 26.6667 6 no
GO:0010647 positive regulation of cell communication 26.6667 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 26.6667 5 no
GO:0023056 positive regulation of signaling 26.6667 4 no
GO:0031325 positive regulation of cellular metabolic process 26.6667 5 no
GO:0034329 cell junction assembly 26.6667 5 no
GO:0034330 cell junction organization 26.6667 4 no
GO:0035567 non-canonical Wnt signaling pathway 26.6667 5 no
GO:0040013 negative regulation of locomotion 26.6667 4 no
GO:0042981 regulation of apoptotic process 26.6667 5 no
GO:0043067 regulation of programmed cell death 26.6667 4 no
GO:0050807 regulation of synapse organization 26.6667 5 no
GO:0051495 positive regulation of cytoskeleton organization 26.6667 7 no
GO:0060071 Wnt signaling pathway, planar cell polarity pathway 26.6667 6 no
GO:0071310 cellular response to organic substance 26.6667 4 no
GO:0110053 regulation of actin filament organization 26.6667 6 no
GO:1902531 regulation of intracellular signal transduction 26.6667 5 no
GO:1902533 positive regulation of intracellular signal transduction 26.6667 6 no
GO:1902903 regulation of supramolecular fiber organization 26.6667 5 no
GO:1902905 positive regulation of supramolecular fiber organization 26.6667 6 no
GO:0008104 protein localization 26.6667 4 no
GO:0008284 positive regulation of cell population proliferation 26.6667 5 no
GO:0010591 regulation of lamellipodium assembly 26.6667 7 no
GO:0010592 positive regulation of lamellipodium assembly 26.6667 7 no
GO:0031346 positive regulation of cell projection organization 26.6667 6 no
GO:0032101 regulation of response to external stimulus 26.6667 4 no
GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 26.6667 6 no
GO:1902743 regulation of lamellipodium organization 26.6667 7 no
GO:1902745 positive regulation of lamellipodium organization 26.6667 7 no
GO:0010648 negative regulation of cell communication 20.0000 5 yes
GO:0023057 negative regulation of signaling 20.0000 4 yes
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 13.3333 5 yes
GO:0050804 modulation of chemical synaptic transmission 13.3333 5 yes
GO:0050805 negative regulation of synaptic transmission 13.3333 5 yes
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 13.3333 4 yes
GO:0099177 regulation of trans-synaptic signaling 13.3333 4 yes
GO:0099560 synaptic membrane adhesion 13.3333 5 yes
GO:1904071 presynaptic active zone assembly 13.3333 5 yes
GO:1990709 presynaptic active zone organization 13.3333 4 yes
GO:2000807 regulation of synaptic vesicle clustering 13.3333 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ZP3_HUMAN [view interactions] Low throughput no no
PCD17_HUMAN [view entry] [view interactions] Low throughput yes yes
UBQL4_HUMAN [view interactions] High throughput no yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
BRK1_HUMAN [view interactions] High throughput no no
CAC1C_HUMAN [view entry] [view interactions] High throughput yes no
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
T22D4_HUMAN [view entry] [view interactions] High throughput yes no
ABI2_HUMAN [view entry] [view interactions] High throughput yes yes
MYB_HUMAN [view interactions] High throughput no yes
NR1H2_HUMAN [view interactions] High throughput no yes
YAF2_HUMAN [view interactions] High throughput no yes
CC50B_HUMAN [view interactions] High throughput no yes
PCD12_HUMAN [view interactions] High throughput no no
FLRT1_HUMAN [view interactions] High throughput no no
PCD20_HUMAN [view interactions] High throughput no no
FCGR1_HUMAN [view interactions] High throughput no no
RN123_HUMAN [view interactions] High throughput no yes
DX39A_HUMAN [view interactions] High throughput no yes
LSME2_HUMAN [view interactions] High throughput no no
RYK_HUMAN [view entry] [view interactions] High throughput yes no
FCGRN_HUMAN [view interactions] High throughput no yes
SPSB4_HUMAN [view interactions] High throughput no no
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RHOQ_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOC_HUMAN [view interactions] High throughput no no
RHOD_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
RHOU_HUMAN [view interactions] High throughput no no
RHOV_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
RND2_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no