Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PCD17_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Potential calcium-dependent cell-adhesion protein. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI004111 LIG_WRC_WIRS_1 LIG 998 1003 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PCD17_HUMAN
GO:0016462 pyrophosphatase activity 66.6667 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 66.6667 4 no
GO:0017076 purine nucleotide binding 66.6667 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 66.6667 6 no
GO:0019900 kinase binding 66.6667 4 no
GO:0032555 purine ribonucleotide binding 66.6667 4 no
GO:0035639 purine ribonucleoside triphosphate binding 66.6667 4 no
GO:0003924 GTPase activity 58.3333 7 no
GO:0005525 GTP binding 58.3333 5 no
GO:0019001 guanyl nucleotide binding 58.3333 5 no
GO:0019901 protein kinase binding 58.3333 5 no
GO:0032561 guanyl ribonucleotide binding 58.3333 5 no
GO:0005509 calcium ion binding 16.6667 5 yes
GO:0046872 metal ion binding 16.6667 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PCD17_HUMAN
GO:0022607 cellular component assembly 83.3333 4 yes
GO:0006996 organelle organization 75.0000 4 no
GO:0048522 positive regulation of cellular process 75.0000 4 no
GO:0048523 negative regulation of cellular process 66.6667 4 yes
GO:0007010 cytoskeleton organization 66.6667 5 no
GO:0007015 actin filament organization 66.6667 5 no
GO:0007264 small GTPase mediated signal transduction 66.6667 4 no
GO:0022603 regulation of anatomical structure morphogenesis 66.6667 4 no
GO:0032956 regulation of actin cytoskeleton organization 66.6667 5 no
GO:0032970 regulation of actin filament-based process 66.6667 4 no
GO:0033043 regulation of organelle organization 66.6667 5 no
GO:0051128 regulation of cellular component organization 66.6667 4 no
GO:0051493 regulation of cytoskeleton organization 66.6667 6 no
GO:0097435 supramolecular fiber organization 66.6667 4 no
GO:0007265 Ras protein signal transduction 58.3333 5 no
GO:0022604 regulation of cell morphogenesis 58.3333 5 no
GO:0008360 regulation of cell shape 50.0000 6 no
GO:0030030 cell projection organization 50.0000 4 no
GO:0030155 regulation of cell adhesion 50.0000 4 no
GO:0030865 cortical cytoskeleton organization 50.0000 6 no
GO:0031323 regulation of cellular metabolic process 50.0000 4 no
GO:0031344 regulation of cell projection organization 50.0000 5 no
GO:0044087 regulation of cellular component biogenesis 50.0000 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 50.0000 6 no
GO:0051171 regulation of nitrogen compound metabolic process 50.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0080090 regulation of primary metabolic process 50.0000 4 no
GO:0010646 regulation of cell communication 41.6667 4 yes
GO:0010324 membrane invagination 41.6667 5 no
GO:0010810 regulation of cell-substrate adhesion 41.6667 5 no
GO:0030031 cell projection assembly 41.6667 5 no
GO:0030334 regulation of cell migration 41.6667 5 no
GO:0031175 neuron projection development 41.6667 6 no
GO:0044089 positive regulation of cellular component biogenesis 41.6667 5 no
GO:0048584 positive regulation of response to stimulus 41.6667 4 no
GO:0051130 positive regulation of cellular component organization 41.6667 5 no
GO:0060491 regulation of cell projection assembly 41.6667 5 no
GO:0061024 membrane organization 41.6667 4 no
GO:0099024 plasma membrane invagination 41.6667 6 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 41.6667 6 no
GO:0120036 plasma membrane bounded cell projection organization 41.6667 5 no
GO:2000145 regulation of cell motility 41.6667 4 no
GO:0051094 positive regulation of developmental process 41.6667 4 no
GO:0009893 positive regulation of metabolic process 41.6667 4 no
GO:0010468 regulation of gene expression 41.6667 5 no
GO:0010604 positive regulation of macromolecule metabolic process 41.6667 5 no
GO:0045785 positive regulation of cell adhesion 41.6667 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 41.6667 5 no
GO:0002684 positive regulation of immune system process 33.3333 4 no
GO:0002685 regulation of leukocyte migration 33.3333 4 no
GO:0006911 phagocytosis, engulfment 33.3333 7 no
GO:0010591 regulation of lamellipodium assembly 33.3333 7 no
GO:0010592 positive regulation of lamellipodium assembly 33.3333 7 no
GO:0016601 Rac protein signal transduction 33.3333 6 no
GO:0030335 positive regulation of cell migration 33.3333 6 no
GO:0031346 positive regulation of cell projection organization 33.3333 6 no
GO:0040017 positive regulation of locomotion 33.3333 4 no
GO:0042127 regulation of cell population proliferation 33.3333 4 no
GO:0051049 regulation of transport 33.3333 4 no
GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 33.3333 6 no
GO:1902743 regulation of lamellipodium organization 33.3333 7 no
GO:1902745 positive regulation of lamellipodium organization 33.3333 7 no
GO:2000147 positive regulation of cell motility 33.3333 5 no
GO:0007266 Rho protein signal transduction 33.3333 6 no
GO:0010941 regulation of cell death 33.3333 4 no
GO:0010942 positive regulation of cell death 33.3333 5 no
GO:0042981 regulation of apoptotic process 33.3333 6 no
GO:0043065 positive regulation of apoptotic process 33.3333 7 no
GO:0043067 regulation of programmed cell death 33.3333 5 no
GO:0043068 positive regulation of programmed cell death 33.3333 6 no
GO:0010638 positive regulation of organelle organization 33.3333 6 no
GO:0051495 positive regulation of cytoskeleton organization 33.3333 7 no
GO:0110053 regulation of actin filament organization 33.3333 6 no
GO:1902903 regulation of supramolecular fiber organization 33.3333 5 no
GO:1902905 positive regulation of supramolecular fiber organization 33.3333 6 no
GO:0043085 positive regulation of catalytic activity 33.3333 4 no
GO:0009889 regulation of biosynthetic process 33.3333 4 no
GO:0016055 Wnt signaling pathway 33.3333 5 no
GO:0031325 positive regulation of cellular metabolic process 33.3333 5 no
GO:0031326 regulation of cellular biosynthetic process 33.3333 5 no
GO:0045595 regulation of cell differentiation 33.3333 4 no
GO:0045597 positive regulation of cell differentiation 33.3333 5 no
GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling 33.3333 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 33.3333 5 no
GO:0010648 negative regulation of cell communication 25.0000 5 yes
GO:0023057 negative regulation of signaling 25.0000 4 yes
GO:0002687 positive regulation of leukocyte migration 25.0000 5 no
GO:0002694 regulation of leukocyte activation 25.0000 4 no
GO:0007411 axon guidance 25.0000 8 no
GO:0008045 motor neuron axon guidance 25.0000 9 no
GO:0008284 positive regulation of cell population proliferation 25.0000 5 no
GO:0032880 regulation of protein localization 25.0000 5 no
GO:0043652 engulfment of apoptotic cell 25.0000 8 no
GO:0050863 regulation of T cell activation 25.0000 6 no
GO:0050865 regulation of cell activation 25.0000 4 no
GO:0051249 regulation of lymphocyte activation 25.0000 5 no
GO:0060341 regulation of cellular localization 25.0000 4 no
GO:0060627 regulation of vesicle-mediated transport 25.0000 4 no
GO:0097485 neuron projection guidance 25.0000 7 no
GO:1902622 regulation of neutrophil migration 25.0000 5 no
GO:1903829 positive regulation of protein localization 25.0000 5 no
GO:2000377 regulation of reactive oxygen species metabolic process 25.0000 5 no
GO:0008104 protein localization 25.0000 4 no
GO:0010594 regulation of endothelial cell migration 25.0000 5 no
GO:0010632 regulation of epithelial cell migration 25.0000 4 no
GO:0030336 negative regulation of cell migration 25.0000 6 no
GO:0040013 negative regulation of locomotion 25.0000 4 no
GO:0051240 positive regulation of multicellular organismal process 25.0000 4 no
GO:0051726 regulation of cell cycle 25.0000 4 no
GO:2000146 negative regulation of cell motility 25.0000 5 no
GO:0000904 cell morphogenesis involved in differentiation 25.0000 4 no
GO:0006796 phosphate-containing compound metabolic process 25.0000 4 no
GO:0034329 cell junction assembly 25.0000 5 no
GO:0034330 cell junction organization 25.0000 4 no
GO:0045216 cell-cell junction organization 25.0000 5 no
GO:0050807 regulation of synapse organization 25.0000 5 no
GO:0051246 regulation of protein metabolic process 25.0000 5 no
GO:0051247 positive regulation of protein metabolic process 25.0000 6 no
GO:0051336 regulation of hydrolase activity 25.0000 4 no
GO:0051345 positive regulation of hydrolase activity 25.0000 5 no
GO:0071310 cellular response to organic substance 25.0000 4 no
GO:0009892 negative regulation of metabolic process 25.0000 4 no
GO:0009966 regulation of signal transduction 25.0000 4 no
GO:0009967 positive regulation of signal transduction 25.0000 5 no
GO:0010562 positive regulation of phosphorus metabolic process 25.0000 6 no
GO:0010647 positive regulation of cell communication 25.0000 5 no
GO:0010720 positive regulation of cell development 25.0000 6 no
GO:0010769 regulation of cell morphogenesis involved in differentiation 25.0000 6 no
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 25.0000 7 no
GO:0010811 positive regulation of cell-substrate adhesion 25.0000 6 no
GO:0019220 regulation of phosphate metabolic process 25.0000 6 no
GO:0023056 positive regulation of signaling 25.0000 4 no
GO:0032231 regulation of actin filament bundle assembly 25.0000 5 no
GO:0032233 positive regulation of actin filament bundle assembly 25.0000 6 no
GO:0035567 non-canonical Wnt signaling pathway 25.0000 6 no
GO:0042325 regulation of phosphorylation 25.0000 7 no
GO:0042327 positive regulation of phosphorylation 25.0000 8 no
GO:0043254 regulation of protein-containing complex assembly 25.0000 5 no
GO:0045937 positive regulation of phosphate metabolic process 25.0000 7 no
GO:0051129 negative regulation of cellular component organization 25.0000 5 no
GO:0051174 regulation of phosphorus metabolic process 25.0000 5 no
GO:0051492 regulation of stress fiber assembly 25.0000 6 no
GO:0051496 positive regulation of stress fiber assembly 25.0000 7 no
GO:0060071 Wnt signaling pathway, planar cell polarity pathway 25.0000 7 no
GO:0060284 regulation of cell development 25.0000 5 no
GO:0090175 regulation of establishment of planar polarity 25.0000 6 no
GO:0110020 regulation of actomyosin structure organization 25.0000 6 no
GO:1900024 regulation of substrate adhesion-dependent cell spreading 25.0000 6 no
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 25.0000 7 no
GO:1902531 regulation of intracellular signal transduction 25.0000 5 no
GO:1902533 positive regulation of intracellular signal transduction 25.0000 6 no
GO:2000027 regulation of animal organ morphogenesis 25.0000 5 no
GO:0006355 regulation of DNA-templated transcription 25.0000 6 no
GO:0010556 regulation of macromolecule biosynthetic process 25.0000 5 no
GO:0051252 regulation of RNA metabolic process 25.0000 5 no
GO:1903506 regulation of nucleic acid-templated transcription 25.0000 7 no
GO:2001141 regulation of RNA biosynthetic process 25.0000 6 no
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 16.6667 5 yes
GO:0050804 modulation of chemical synaptic transmission 16.6667 5 yes
GO:0050805 negative regulation of synaptic transmission 16.6667 5 yes
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 16.6667 4 yes
GO:0099177 regulation of trans-synaptic signaling 16.6667 4 yes
GO:0099560 synaptic membrane adhesion 16.6667 5 yes
GO:1904071 presynaptic active zone assembly 16.6667 5 yes
GO:1990709 presynaptic active zone organization 16.6667 4 yes
GO:2000807 regulation of synaptic vesicle clustering 16.6667 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PCD17_HUMAN [view entry] [view interactions] Low throughput yes yes
ZP3_HUMAN [view interactions] Low throughput no no
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOC_HUMAN [view interactions] High throughput no no
RHOD_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
RHOU_HUMAN [view interactions] High throughput no no
RHOV_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
RND2_HUMAN [view interactions] High throughput no no
UBQL4_HUMAN [view interactions] High throughput no yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
BRK1_HUMAN [view interactions] High throughput no no
T22D4_HUMAN [view entry] [view interactions] High throughput yes no
ABI2_HUMAN [view entry] [view interactions] High throughput yes yes
MYB_HUMAN [view interactions] High throughput no yes
NR1H2_HUMAN [view interactions] High throughput no yes
YAF2_HUMAN [view interactions] High throughput no yes
CC50B_HUMAN [view interactions] High throughput no yes
PCD12_HUMAN [view interactions] High throughput no no
FLRT1_HUMAN [view interactions] High throughput no no
PCD20_HUMAN [view interactions] High throughput no no
FCGR1_HUMAN [view interactions] High throughput no no
RN123_HUMAN [view interactions] High throughput no yes
DX39A_HUMAN [view interactions] High throughput no yes
LSME2_HUMAN [view interactions] High throughput no no
RYK_HUMAN [view interactions] High throughput no no
FCGRN_HUMAN [view interactions] High throughput no yes
SPSB4_HUMAN [view interactions] High throughput no no
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RHOQ_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes