Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SEM3F_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

May play a role in cell motility and cell adhesion. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI003999 LIG_NRP_CendR_1 LIG 778 779 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SEM3F_HUMAN
GO:0017154 semaphorin receptor activity 57.1429 4 no
GO:0004713 protein tyrosine kinase activity 28.5714 4 no
GO:0004714 transmembrane receptor protein tyrosine kinase activity 28.5714 5 no
GO:0005021 vascular endothelial growth factor receptor activity 28.5714 6 no
GO:0016301 kinase activity 28.5714 4 no
GO:0016773 phosphotransferase activity, alcohol group as acceptor 28.5714 4 no
GO:0019199 transmembrane receptor protein kinase activity 28.5714 4 no
GO:0046872 metal ion binding 28.5714 4 no
GO:0003723 RNA binding 28.5714 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in SEM3F_HUMAN
GO:0030334 regulation of cell migration 71.4286 5 yes
GO:0048522 positive regulation of cellular process 71.4286 4 yes
GO:0051128 regulation of cellular component organization 71.4286 4 yes
GO:0071526 semaphorin-plexin signaling pathway 71.4286 4 yes
GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 71.4286 5 yes
GO:1990138 neuron projection extension 71.4286 4 yes
GO:2000145 regulation of cell motility 71.4286 4 yes
GO:0007411 axon guidance 57.1429 8 yes
GO:0010975 regulation of neuron projection development 57.1429 7 yes
GO:0021612 facial nerve structural organization 57.1429 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 57.1429 4 yes
GO:0030030 cell projection organization 57.1429 4 yes
GO:0031175 neuron projection development 57.1429 6 yes
GO:0031344 regulation of cell projection organization 57.1429 5 yes
GO:0045595 regulation of cell differentiation 57.1429 4 yes
GO:0048523 negative regulation of cellular process 57.1429 4 yes
GO:0050767 regulation of neurogenesis 57.1429 6 yes
GO:0050770 regulation of axonogenesis 57.1429 5 yes
GO:0051960 regulation of nervous system development 57.1429 5 yes
GO:0060284 regulation of cell development 57.1429 5 yes
GO:0097485 neuron projection guidance 57.1429 7 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 57.1429 6 yes
GO:0120036 plasma membrane bounded cell projection organization 57.1429 5 yes
GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance 57.1429 6 yes
GO:2000026 regulation of multicellular organismal development 57.1429 4 yes
GO:0001558 regulation of cell growth 42.8571 4 yes
GO:0001667 ameboidal-type cell migration 42.8571 4 yes
GO:0001755 neural crest cell migration 42.8571 6 yes
GO:0008045 motor neuron axon guidance 42.8571 9 yes
GO:0010721 negative regulation of cell development 42.8571 6 yes
GO:0010977 negative regulation of neuron projection development 42.8571 7 yes
GO:0021637 trigeminal nerve structural organization 42.8571 4 yes
GO:0021785 branchiomotor neuron axon guidance 42.8571 10 yes
GO:0030308 negative regulation of cell growth 42.8571 5 yes
GO:0030335 positive regulation of cell migration 42.8571 6 yes
GO:0030516 regulation of axon extension 42.8571 5 yes
GO:0030517 negative regulation of axon extension 42.8571 6 yes
GO:0031345 negative regulation of cell projection organization 42.8571 6 yes
GO:0032101 regulation of response to external stimulus 42.8571 4 yes
GO:0032102 negative regulation of response to external stimulus 42.8571 5 yes
GO:0036484 trunk neural crest cell migration 42.8571 7 yes
GO:0036486 ventral trunk neural crest cell migration 42.8571 8 yes
GO:0040013 negative regulation of locomotion 42.8571 4 yes
GO:0040017 positive regulation of locomotion 42.8571 4 yes
GO:0045596 negative regulation of cell differentiation 42.8571 5 yes
GO:0045926 negative regulation of growth 42.8571 4 yes
GO:0048585 negative regulation of response to stimulus 42.8571 4 yes
GO:0048638 regulation of developmental growth 42.8571 4 yes
GO:0048640 negative regulation of developmental growth 42.8571 5 yes
GO:0048675 axon extension 42.8571 5 yes
GO:0048841 regulation of axon extension involved in axon guidance 42.8571 6 yes
GO:0048843 negative regulation of axon extension involved in axon guidance 42.8571 6 yes
GO:0048846 axon extension involved in axon guidance 42.8571 6 yes
GO:0050768 negative regulation of neurogenesis 42.8571 6 yes
GO:0050771 negative regulation of axonogenesis 42.8571 6 yes
GO:0050919 negative chemotaxis 42.8571 4 yes
GO:0050920 regulation of chemotaxis 42.8571 4 yes
GO:0050922 negative regulation of chemotaxis 42.8571 5 yes
GO:0051093 negative regulation of developmental process 42.8571 4 yes
GO:0051129 negative regulation of cellular component organization 42.8571 5 yes
GO:0051241 negative regulation of multicellular organismal process 42.8571 4 yes
GO:0051961 negative regulation of nervous system development 42.8571 5 yes
GO:0061387 regulation of extent of cell growth 42.8571 5 yes
GO:0061548 ganglion development 42.8571 4 yes
GO:0061549 sympathetic ganglion development 42.8571 5 yes
GO:0090497 mesenchymal cell migration 42.8571 5 yes
GO:0097490 sympathetic neuron projection extension 42.8571 5 yes
GO:0097491 sympathetic neuron projection guidance 42.8571 8 yes
GO:1901166 neural crest cell migration involved in autonomic nervous system development 42.8571 7 yes
GO:1902284 neuron projection extension involved in neuron projection guidance 42.8571 5 yes
GO:2000147 positive regulation of cell motility 42.8571 5 yes
GO:0010720 positive regulation of cell development 42.8571 6 no
GO:0022604 regulation of cell morphogenesis 42.8571 5 no
GO:0030155 regulation of cell adhesion 42.8571 4 no
GO:0031346 positive regulation of cell projection organization 42.8571 6 no
GO:0045597 positive regulation of cell differentiation 42.8571 5 no
GO:0050769 positive regulation of neurogenesis 42.8571 6 no
GO:0050772 positive regulation of axonogenesis 42.8571 6 no
GO:0051094 positive regulation of developmental process 42.8571 4 no
GO:0051130 positive regulation of cellular component organization 42.8571 5 no
GO:0051240 positive regulation of multicellular organismal process 42.8571 4 no
GO:0051962 positive regulation of nervous system development 42.8571 5 no
GO:0050807 regulation of synapse organization 28.5714 5 yes
GO:0099175 regulation of postsynapse organization 28.5714 6 yes
GO:0001764 neuron migration 28.5714 4 no
GO:0001936 regulation of endothelial cell proliferation 28.5714 6 no
GO:0001938 positive regulation of endothelial cell proliferation 28.5714 7 no
GO:0003148 outflow tract septum morphogenesis 28.5714 4 no
GO:0008284 positive regulation of cell population proliferation 28.5714 5 no
GO:0010594 regulation of endothelial cell migration 28.5714 5 no
GO:0010595 positive regulation of endothelial cell migration 28.5714 6 no
GO:0010632 regulation of epithelial cell migration 28.5714 4 no
GO:0010634 positive regulation of epithelial cell migration 28.5714 5 no
GO:0021649 vestibulocochlear nerve structural organization 28.5714 4 no
GO:0021828 gonadotrophin-releasing hormone neuronal migration to the hypothalamus 28.5714 5 no
GO:0021855 hypothalamus cell migration 28.5714 4 no
GO:0021856 hypothalamic tangential migration using cell-axon interactions 28.5714 5 no
GO:0042127 regulation of cell population proliferation 28.5714 4 no
GO:0050678 regulation of epithelial cell proliferation 28.5714 5 no
GO:0050679 positive regulation of epithelial cell proliferation 28.5714 6 no
GO:0061550 cranial ganglion development 28.5714 5 no
GO:0061551 trigeminal ganglion development 28.5714 6 no
GO:0061552 ganglion morphogenesis 28.5714 4 no
GO:0071310 cellular response to organic substance 28.5714 4 no
GO:0097374 sensory neuron axon guidance 28.5714 9 no
GO:1903375 facioacoustic ganglion development 28.5714 6 no
GO:1904835 dorsal root ganglion morphogenesis 28.5714 5 no
GO:0006508 proteolysis 28.5714 4 no
GO:0009057 macromolecule catabolic process 28.5714 4 no
GO:0016567 protein ubiquitination 28.5714 7 no
GO:0019941 modification-dependent protein catabolic process 28.5714 6 no
GO:0032446 protein modification by small protein conjugation 28.5714 6 no
GO:0036211 protein modification process 28.5714 4 no
GO:0043412 macromolecule modification 28.5714 4 no
GO:0043632 modification-dependent macromolecule catabolic process 28.5714 5 no
GO:0044265 cellular macromolecule catabolic process 28.5714 4 no
GO:0051603 proteolysis involved in protein catabolic process 28.5714 5 no
GO:0070647 protein modification by small protein conjugation or removal 28.5714 5 no
GO:0002009 morphogenesis of an epithelium 28.5714 4 no
GO:0010638 positive regulation of organelle organization 28.5714 6 no
GO:0014910 regulation of smooth muscle cell migration 28.5714 6 no
GO:0033043 regulation of organelle organization 28.5714 5 no
GO:0051493 regulation of cytoskeleton organization 28.5714 6 no
GO:0051495 positive regulation of cytoskeleton organization 28.5714 7 no
GO:0060600 dichotomous subdivision of an epithelial terminal unit 28.5714 5 no
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 28.5714 6 no
GO:0007162 negative regulation of cell adhesion 28.5714 5 no
GO:0008360 regulation of cell shape 28.5714 6 no
GO:0043087 regulation of GTPase activity 28.5714 5 no
GO:0051336 regulation of hydrolase activity 28.5714 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NRP1_HUMAN [view entry] [view interactions] Low throughput yes yes
NRP2_HUMAN [view entry] [view interactions] Low throughput yes yes
S35G2_HUMAN [view interactions] High throughput no yes
UBA1_HUMAN [view entry] [view interactions] High throughput yes yes
SHBG_HUMAN [view interactions] High throughput no no
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
SEM3C_HUMAN [view interactions] High throughput no no
PGFRA_HUMAN [view interactions] High throughput no no
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
PLXD1_HUMAN [view interactions] Computational no yes
PLXB3_HUMAN [view interactions] Computational no yes
PLXC1_HUMAN [view interactions] Computational no no
PLXB1_HUMAN [view interactions] Computational no yes
PLXB2_HUMAN [view interactions] Computational no yes
PLXA3_HUMAN [view entry] [view interactions] Computational yes no
PLXA1_HUMAN [view entry] [view interactions] Computational yes yes