Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CCG7_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (PubMed). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity only for GRIA1 and GRIA2 (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CCG7_HUMAN
GO:0008324 monoatomic cation transmembrane transporter activity 28.5714 4 yes
GO:0022890 inorganic cation transmembrane transporter activity 28.5714 4 yes
GO:0000295 adenine nucleotide transmembrane transporter activity 28.5714 6 no
GO:0005346 purine ribonucleotide transmembrane transporter activity 28.5714 4 no
GO:0005347 ATP transmembrane transporter activity 28.5714 4 no
GO:0005471 ATP:ADP antiporter activity 28.5714 5 no
GO:0015215 nucleotide transmembrane transporter activity 28.5714 4 no
GO:0015216 purine nucleotide transmembrane transporter activity 28.5714 5 no
GO:0015217 ADP transmembrane transporter activity 28.5714 4 no
GO:0015291 secondary active transmembrane transporter activity 28.5714 4 no
GO:0015297 antiporter activity 28.5714 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in CCG7_HUMAN
GO:0051128 regulation of cellular component organization 85.7143 4 yes
GO:0071702 organic substance transport 85.7143 4 yes
GO:0071705 nitrogen compound transport 85.7143 4 yes
GO:0010646 regulation of cell communication 85.7143 4 yes
GO:0048522 positive regulation of cellular process 71.4286 4 yes
GO:0006996 organelle organization 71.4286 4 no
GO:0009966 regulation of signal transduction 71.4286 4 yes
GO:0048523 negative regulation of cellular process 57.1429 4 no
GO:0006886 intracellular protein transport 57.1429 4 yes
GO:0008104 protein localization 57.1429 4 yes
GO:0015031 protein transport 57.1429 4 yes
GO:0051049 regulation of transport 42.8571 4 yes
GO:0060255 regulation of macromolecule metabolic process 42.8571 4 yes
GO:0080090 regulation of primary metabolic process 42.8571 4 yes
GO:0006839 mitochondrial transport 42.8571 4 no
GO:0007005 mitochondrion organization 42.8571 5 no
GO:0007006 mitochondrial membrane organization 42.8571 5 no
GO:0009968 negative regulation of signal transduction 42.8571 5 no
GO:0010648 negative regulation of cell communication 42.8571 5 no
GO:0023057 negative regulation of signaling 42.8571 4 no
GO:0033043 regulation of organelle organization 42.8571 5 no
GO:0042981 regulation of apoptotic process 42.8571 5 no
GO:0043066 negative regulation of apoptotic process 42.8571 6 no
GO:0043067 regulation of programmed cell death 42.8571 4 no
GO:0043069 negative regulation of programmed cell death 42.8571 5 no
GO:0048585 negative regulation of response to stimulus 42.8571 4 no
GO:0051129 negative regulation of cellular component organization 42.8571 5 no
GO:0061024 membrane organization 42.8571 4 no
GO:0009894 regulation of catabolic process 42.8571 4 yes
GO:0031323 regulation of cellular metabolic process 28.5714 4 yes
GO:0033365 protein localization to organelle 28.5714 5 yes
GO:0035418 protein localization to synapse 28.5714 6 yes
GO:0050804 modulation of chemical synaptic transmission 28.5714 5 yes
GO:0072594 establishment of protein localization to organelle 28.5714 4 yes
GO:0072657 protein localization to membrane 28.5714 4 yes
GO:0099177 regulation of trans-synaptic signaling 28.5714 4 yes
GO:1902414 protein localization to cell junction 28.5714 5 yes
GO:0006862 nucleotide transport 28.5714 6 no
GO:0010639 negative regulation of organelle organization 28.5714 6 no
GO:0010821 regulation of mitochondrion organization 28.5714 6 no
GO:0015711 organic anion transport 28.5714 5 no
GO:0015748 organophosphate ester transport 28.5714 5 no
GO:0015865 purine nucleotide transport 28.5714 7 no
GO:0015866 ADP transport 28.5714 6 no
GO:0015867 ATP transport 28.5714 6 no
GO:0015868 purine ribonucleotide transport 28.5714 6 no
GO:0015931 nucleobase-containing compound transport 28.5714 5 no
GO:0035795 negative regulation of mitochondrial membrane permeability 28.5714 5 no
GO:0046902 regulation of mitochondrial membrane permeability 28.5714 4 no
GO:0051503 adenine nucleotide transport 28.5714 8 no
GO:0140021 mitochondrial ADP transmembrane transport 28.5714 4 no
GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 28.5714 5 no
GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 28.5714 6 no
GO:1901264 carbohydrate derivative transport 28.5714 5 no
GO:1905709 negative regulation of membrane permeability 28.5714 4 no
GO:1990544 mitochondrial ATP transmembrane transport 28.5714 4 no
GO:2001233 regulation of apoptotic signaling pathway 28.5714 5 no
GO:2001234 negative regulation of apoptotic signaling pathway 28.5714 6 no
GO:0009893 positive regulation of metabolic process 28.5714 4 no
GO:0030334 regulation of cell migration 28.5714 5 no
GO:0030335 positive regulation of cell migration 28.5714 6 no
GO:0040017 positive regulation of locomotion 28.5714 4 no
GO:0051246 regulation of protein metabolic process 28.5714 5 no
GO:1902531 regulation of intracellular signal transduction 28.5714 5 no
GO:2000145 regulation of cell motility 28.5714 4 no
GO:2000147 positive regulation of cell motility 28.5714 5 no
GO:0051130 positive regulation of cellular component organization 28.5714 5 no
GO:0007010 cytoskeleton organization 28.5714 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
MAP1A_HUMAN [view entry] [view interactions] Low throughput yes yes
SACA1_HUMAN [view interactions] High throughput no no
ADT1_HUMAN [view entry] [view interactions] High throughput yes yes
TSYL1_HUMAN [view interactions] High throughput no yes
RAB7L_HUMAN [view interactions] High throughput no yes
CY24A_HUMAN [view interactions] High throughput no no
DRB1_HUMAN [view interactions] High throughput no no
FBXL6_HUMAN [view interactions] High throughput no no
ACSL1_HUMAN [view interactions] High throughput no no
ADT3_HUMAN [view entry] [view interactions] High throughput yes yes
IQEC1_HUMAN [view entry] [view interactions] High throughput yes yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
KIRR1_HUMAN [view interactions] High throughput no no
FUT8_HUMAN [view interactions] High throughput no yes
SAM50_HUMAN [view entry] [view interactions] High throughput yes yes
S38A5_HUMAN [view interactions] High throughput no yes
UCK2_HUMAN [view interactions] High throughput no no
VRK2_HUMAN [view interactions] High throughput no no
PLD2_HUMAN [view interactions] High throughput no yes
CEP78_HUMAN [view interactions] High throughput no yes