LRRT1_HUMAN
Evidence for PS localization
Functions
Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
No data found.
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in LRRT1_HUMAN |
|---|---|---|---|---|
| GO:0008104 | protein localization | 50.0000 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 50.0000 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 40.0000 | 4 | yes |
| GO:0050807 | regulation of synapse organization | 40.0000 | 5 | yes |
| GO:0072657 | protein localization to membrane | 40.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 30.0000 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 30.0000 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 30.0000 | 4 | yes |
| GO:0035418 | protein localization to synapse | 30.0000 | 6 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 30.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 30.0000 | 4 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 30.0000 | 5 | yes |
| GO:0050806 | positive regulation of synaptic transmission | 30.0000 | 5 | yes |
| GO:0051049 | regulation of transport | 30.0000 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 30.0000 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 30.0000 | 5 | yes |
| GO:0051963 | regulation of synapse assembly | 30.0000 | 6 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 30.0000 | 4 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 30.0000 | 4 | yes |
| GO:1901888 | regulation of cell junction assembly | 30.0000 | 5 | yes |
| GO:1902414 | protein localization to cell junction | 30.0000 | 5 | yes |
| GO:0015031 | protein transport | 30.0000 | 4 | no |
| GO:0071702 | organic substance transport | 30.0000 | 4 | no |
| GO:0071705 | nitrogen compound transport | 30.0000 | 4 | no |
| GO:0006996 | organelle organization | 30.0000 | 4 | no |
| GO:1990778 | protein localization to cell periphery | 30.0000 | 5 | no |
| GO:0002090 | regulation of receptor internalization | 20.0000 | 7 | yes |
| GO:0002091 | negative regulation of receptor internalization | 20.0000 | 7 | yes |
| GO:0030100 | regulation of endocytosis | 20.0000 | 5 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 20.0000 | 5 | yes |
| GO:0045806 | negative regulation of endocytosis | 20.0000 | 5 | yes |
| GO:0048259 | regulation of receptor-mediated endocytosis | 20.0000 | 6 | yes |
| GO:0048261 | negative regulation of receptor-mediated endocytosis | 20.0000 | 6 | yes |
| GO:0051051 | negative regulation of transport | 20.0000 | 4 | yes |
| GO:0051129 | negative regulation of cellular component organization | 20.0000 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 20.0000 | 4 | yes |
| GO:0051960 | regulation of nervous system development | 20.0000 | 5 | yes |
| GO:0051962 | positive regulation of nervous system development | 20.0000 | 5 | yes |
| GO:0051965 | positive regulation of synapse assembly | 20.0000 | 6 | yes |
| GO:0099174 | regulation of presynapse organization | 20.0000 | 6 | yes |
| GO:0099175 | regulation of postsynapse organization | 20.0000 | 6 | yes |
| GO:1901890 | positive regulation of cell junction assembly | 20.0000 | 6 | yes |
| GO:1905606 | regulation of presynapse assembly | 20.0000 | 7 | yes |
| GO:2000026 | regulation of multicellular organismal development | 20.0000 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM223_HUMAN | [view interactions] | High throughput | no | yes |
| UPK3L_HUMAN | [view interactions] | High throughput | no | yes |
| FRAS1_HUMAN | [view interactions] | High throughput | no | yes |
| SPTC2_HUMAN | [view interactions] | High throughput | no | no |
| TSN6_HUMAN | [view interactions] | High throughput | no | yes |
| NSMA_HUMAN | [view interactions] | High throughput | no | yes |
| SUN1_HUMAN | [view interactions] | High throughput | no | yes |
| OSBP1_HUMAN | [view interactions] | High throughput | no | yes |
| PDE3B_HUMAN | [view interactions] | High throughput | no | no |
| STIM1_HUMAN | [view interactions] | High throughput | no | yes |
| TBB8_HUMAN | [view interactions] | High throughput | no | no |
| RAB12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RETST_HUMAN | [view interactions] | High throughput | no | yes |
| LRP11_HUMAN | [view interactions] | High throughput | no | no |
| AMGO1_HUMAN | [view interactions] | High throughput | no | yes |
| CISD2_HUMAN | [view interactions] | High throughput | no | yes |
| PDZD8_HUMAN | [view interactions] | High throughput | no | yes |
| TM131_HUMAN | [view interactions] | High throughput | no | yes |
| TTC17_HUMAN | [view interactions] | High throughput | no | yes |
| NGBR_HUMAN | [view interactions] | High throughput | no | no |
| CNPY3_HUMAN | [view interactions] | High throughput | no | yes |
| LRFN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSUN3_HUMAN | [view interactions] | High throughput | no | no |
| TM39A_HUMAN | [view interactions] | High throughput | no | yes |
| TYW1_HUMAN | [view interactions] | High throughput | no | yes |
| NOCT_HUMAN | [view interactions] | High throughput | no | no |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AREL1_HUMAN | [view interactions] | High throughput | no | no |
| AT2A3_HUMAN | [view interactions] | High throughput | no | yes |
| MARC1_HUMAN | [view interactions] | High throughput | no | yes |
| CA043_HUMAN | [view interactions] | High throughput | no | yes |
| PIGA_HUMAN | [view interactions] | High throughput | no | yes |
| NDC1_HUMAN | [view interactions] | High throughput | no | yes |
| K319L_HUMAN | [view interactions] | High throughput | no | yes |
| AT131_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBE4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCX3_HUMAN | [view interactions] | High throughput | no | no |
| CSTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLPL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDKAL_HUMAN | [view interactions] | High throughput | no | no |
| F263_HUMAN | [view interactions] | High throughput | no | yes |
| TAZ_HUMAN | [view interactions] | High throughput | no | yes |
| UBP33_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| SSR3_HUMAN | [view interactions] | High throughput | no | yes |