Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

TPPC3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May play a role in vesicular transport from endoplasmic reticulum to Golgi. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in TPPC3_HUMAN
GO:0000166 nucleotide binding 26.3158 4 no
GO:0017076 purine nucleotide binding 26.3158 5 no
GO:0032555 purine ribonucleotide binding 26.3158 4 no
GO:0035639 purine ribonucleoside triphosphate binding 26.3158 4 no
GO:0043168 anion binding 26.3158 4 no
GO:0003723 RNA binding 26.3158 4 no
GO:0003779 actin binding 21.0526 4 no
GO:0016462 pyrophosphatase activity 21.0526 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 21.0526 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 21.0526 6 no

Biological process

Term Name % Distance from top the of the tree Annotated in TPPC3_HUMAN
GO:0006996 organelle organization 52.6316 4 yes
GO:0048522 positive regulation of cellular process 52.6316 4 no
GO:0051128 regulation of cellular component organization 52.6316 4 no
GO:0031323 regulation of cellular metabolic process 47.3684 4 no
GO:0060255 regulation of macromolecule metabolic process 47.3684 4 no
GO:0080090 regulation of primary metabolic process 47.3684 4 no
GO:0022607 cellular component assembly 42.1053 4 yes
GO:0009889 regulation of biosynthetic process 42.1053 4 no
GO:0010556 regulation of macromolecule biosynthetic process 42.1053 5 no
GO:0031326 regulation of cellular biosynthetic process 42.1053 5 no
GO:0009893 positive regulation of metabolic process 36.8421 4 no
GO:0010468 regulation of gene expression 36.8421 6 no
GO:0010604 positive regulation of macromolecule metabolic process 36.8421 5 no
GO:0033043 regulation of organelle organization 36.8421 5 no
GO:0044087 regulation of cellular component biogenesis 36.8421 4 no
GO:0048523 negative regulation of cellular process 36.8421 4 no
GO:0051049 regulation of transport 36.8421 4 no
GO:0008104 protein localization 31.5789 4 no
GO:0009892 negative regulation of metabolic process 31.5789 4 no
GO:0009966 regulation of signal transduction 31.5789 4 no
GO:0010646 regulation of cell communication 31.5789 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 31.5789 5 no
GO:0031324 negative regulation of cellular metabolic process 31.5789 5 no
GO:0031325 positive regulation of cellular metabolic process 31.5789 5 no
GO:0048584 positive regulation of response to stimulus 31.5789 4 no
GO:0051130 positive regulation of cellular component organization 31.5789 5 no
GO:0051246 regulation of protein metabolic process 31.5789 5 no
GO:0060341 regulation of cellular localization 31.5789 4 no
GO:0016050 vesicle organization 26.3158 5 yes
GO:0043933 protein-containing complex organization 26.3158 4 yes
GO:0030030 cell projection organization 26.3158 4 no
GO:0031175 neuron projection development 26.3158 6 no
GO:0120036 plasma membrane bounded cell projection organization 26.3158 5 no
GO:0009890 negative regulation of biosynthetic process 26.3158 5 no
GO:0009891 positive regulation of biosynthetic process 26.3158 5 no
GO:0009967 positive regulation of signal transduction 26.3158 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 26.3158 6 no
GO:0010558 negative regulation of macromolecule biosynthetic process 26.3158 6 no
GO:0010605 negative regulation of macromolecule metabolic process 26.3158 5 no
GO:0010647 positive regulation of cell communication 26.3158 5 no
GO:0023056 positive regulation of signaling 26.3158 4 no
GO:0031327 negative regulation of cellular biosynthetic process 26.3158 6 no
GO:0031328 positive regulation of cellular biosynthetic process 26.3158 6 no
GO:0032880 regulation of protein localization 26.3158 5 no
GO:0033365 protein localization to organelle 26.3158 5 no
GO:0051247 positive regulation of protein metabolic process 26.3158 6 no
GO:0071310 cellular response to organic substance 26.3158 4 no
GO:0071702 organic substance transport 26.3158 4 no
GO:0071705 nitrogen compound transport 26.3158 4 no
GO:1902903 regulation of supramolecular fiber organization 26.3158 5 no
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 21.0526 4 yes
GO:0001932 regulation of protein phosphorylation 21.0526 7 no
GO:0006355 regulation of DNA-templated transcription 21.0526 7 no
GO:0010628 positive regulation of gene expression 21.0526 7 no
GO:0010629 negative regulation of gene expression 21.0526 7 no
GO:0010638 positive regulation of organelle organization 21.0526 6 no
GO:0019220 regulation of phosphate metabolic process 21.0526 6 no
GO:0031399 regulation of protein modification process 21.0526 6 no
GO:0031401 positive regulation of protein modification process 21.0526 7 no
GO:0036211 protein modification process 21.0526 4 no
GO:0042325 regulation of phosphorylation 21.0526 7 no
GO:0042981 regulation of apoptotic process 21.0526 5 no
GO:0043067 regulation of programmed cell death 21.0526 4 no
GO:0043412 macromolecule modification 21.0526 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 21.0526 5 no
GO:0048638 regulation of developmental growth 21.0526 4 no
GO:0050804 modulation of chemical synaptic transmission 21.0526 5 no
GO:0050890 cognition 21.0526 4 no
GO:0051094 positive regulation of developmental process 21.0526 4 no
GO:0051129 negative regulation of cellular component organization 21.0526 5 no
GO:0051174 regulation of phosphorus metabolic process 21.0526 5 no
GO:0051252 regulation of RNA metabolic process 21.0526 5 no
GO:0051338 regulation of transferase activity 21.0526 4 no
GO:0080134 regulation of response to stress 21.0526 4 no
GO:0099177 regulation of trans-synaptic signaling 21.0526 4 no
GO:1902531 regulation of intracellular signal transduction 21.0526 5 no
GO:1902533 positive regulation of intracellular signal transduction 21.0526 6 no
GO:2001141 regulation of RNA biosynthetic process 21.0526 6 no
GO:0030334 regulation of cell migration 21.0526 5 no
GO:0042127 regulation of cell population proliferation 21.0526 4 no
GO:0045595 regulation of cell differentiation 21.0526 4 no
GO:0051240 positive regulation of multicellular organismal process 21.0526 4 no
GO:2000145 regulation of cell motility 21.0526 4 no
GO:0007010 cytoskeleton organization 21.0526 5 no
GO:0015031 protein transport 21.0526 4 no
GO:0072594 establishment of protein localization to organelle 21.0526 4 no
GO:0006901 vesicle coating 15.7895 6 yes
GO:0065003 protein-containing complex assembly 15.7895 5 yes
GO:0099022 vesicle tethering 15.7895 4 yes
GO:0048208 COPII vesicle coating 10.5263 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TPC2B_HUMAN [view interactions] Low throughput no no
TPC2A_HUMAN [view interactions] Low throughput no yes
TPPC8_HUMAN [view interactions] Low throughput no yes
TPPC5_HUMAN [view interactions] Low throughput no yes
TPPC1_HUMAN [view interactions] Low throughput no yes
TPC6B_HUMAN [view interactions] Low throughput no yes
TPC6A_HUMAN [view interactions] Low throughput no yes
RAB3I_HUMAN [view interactions] Low throughput no no
TPPC9_HUMAN [view entry] [view interactions] Low throughput yes no
SPAT4_HUMAN [view interactions] Low throughput no no
TPPC4_HUMAN [view entry] [view interactions] Low throughput yes yes
TPC2L_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
TPC13_HUMAN [view interactions] High throughput no yes
AMOL2_HUMAN [view interactions] High throughput no no
TPC11_HUMAN [view interactions] High throughput no no
C102B_HUMAN [view interactions] High throughput no yes
TBC14_HUMAN [view interactions] High throughput no yes
KANK4_HUMAN [view interactions] High throughput no no
B2L14_HUMAN [view interactions] High throughput no yes
TPC12_HUMAN [view interactions] High throughput no yes
VCAM1_HUMAN [view interactions] High throughput no no
HSC20_HUMAN [view interactions] High throughput no yes
CYFP1_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
CDC45_HUMAN [view interactions] High throughput no no
PKHF2_HUMAN [view interactions] High throughput no yes
LAMP1_HUMAN [view entry] [view interactions] High throughput yes yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
TGON2_HUMAN [view entry] [view interactions] High throughput yes yes
NFAC3_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
FGFR1_HUMAN [view entry] [view interactions] High throughput yes yes
INSR_HUMAN [view interactions] High throughput no yes
SWAP1_HUMAN [view interactions] High throughput no no
TPC10_HUMAN [view interactions] High throughput no no
M21D2_HUMAN [view interactions] High throughput no yes
TM102_HUMAN [view interactions] High throughput no no
R3GEF_HUMAN [view interactions] High throughput no yes
PDLI7_HUMAN [view entry] [view interactions] High throughput yes no
DNLI4_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
ST1A2_HUMAN [view interactions] High throughput no no
LYPD3_HUMAN [view interactions] High throughput no no
CABS1_HUMAN [view interactions] High throughput no no
STMN4_HUMAN [view interactions] High throughput no no
BGAL_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
LMBRL_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
HXB6_HUMAN [view interactions] High throughput no no
GAB2_HUMAN [view interactions] High throughput no yes
MTL5_HUMAN [view interactions] High throughput no no
RAB43_HUMAN [view interactions] High throughput no yes
CRYAA_HUMAN [view interactions] High throughput no no
RUFY4_HUMAN [view interactions] High throughput no no
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
FAS_HUMAN [view entry] [view interactions] High throughput yes no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RIT1_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
SC22B_HUMAN [view entry] [view interactions] High throughput yes no
TCPD_HUMAN [view entry] [view interactions] High throughput yes yes
IFM1_HUMAN [view interactions] High throughput no no
IFM3_HUMAN [view interactions] High throughput no yes
ATG9A_HUMAN [view interactions] High throughput no yes
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
DHCR7_HUMAN [view interactions] High throughput no yes
CNPY3_HUMAN [view interactions] High throughput no yes
DDA1_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no