Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ARHG9_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters . [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in ARHG9_HUMAN
GO:0043168 anion binding 45.4545 4 no
GO:0000166 nucleotide binding 36.3636 4 no
GO:0017076 purine nucleotide binding 36.3636 5 no
GO:0032555 purine ribonucleotide binding 36.3636 4 no
GO:0035639 purine ribonucleoside triphosphate binding 36.3636 4 no
GO:0019900 kinase binding 36.3636 4 no
GO:0019901 protein kinase binding 36.3636 5 no
GO:0005524 ATP binding 27.2727 5 no
GO:0030554 adenyl nucleotide binding 27.2727 6 no
GO:0032559 adenyl ribonucleotide binding 27.2727 5 no
GO:0005085 guanyl-nucleotide exchange factor activity 18.1818 5 yes
GO:0030695 GTPase regulator activity 18.1818 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ARHG9_HUMAN
GO:0010646 regulation of cell communication 54.5455 4 yes
GO:0009966 regulation of signal transduction 45.4545 4 yes
GO:0051128 regulation of cellular component organization 45.4545 4 yes
GO:1902531 regulation of intracellular signal transduction 45.4545 5 yes
GO:0048522 positive regulation of cellular process 36.3636 4 no
GO:0048523 negative regulation of cellular process 36.3636 4 no
GO:0060255 regulation of macromolecule metabolic process 36.3636 4 no
GO:0080090 regulation of primary metabolic process 36.3636 4 no
GO:0033043 regulation of organelle organization 36.3636 5 yes
GO:0044087 regulation of cellular component biogenesis 36.3636 4 yes
GO:0008104 protein localization 36.3636 4 no
GO:0001933 negative regulation of protein phosphorylation 27.2727 8 no
GO:0006469 negative regulation of protein kinase activity 27.2727 7 no
GO:0006996 organelle organization 27.2727 4 no
GO:0009892 negative regulation of metabolic process 27.2727 4 no
GO:0009893 positive regulation of metabolic process 27.2727 4 no
GO:0010563 negative regulation of phosphorus metabolic process 27.2727 6 no
GO:0010604 positive regulation of macromolecule metabolic process 27.2727 5 no
GO:0010605 negative regulation of macromolecule metabolic process 27.2727 5 no
GO:0019220 regulation of phosphate metabolic process 27.2727 6 no
GO:0031323 regulation of cellular metabolic process 27.2727 4 no
GO:0031324 negative regulation of cellular metabolic process 27.2727 5 no
GO:0031399 regulation of protein modification process 27.2727 6 no
GO:0031400 negative regulation of protein modification process 27.2727 7 no
GO:0033673 negative regulation of kinase activity 27.2727 6 no
GO:0042325 regulation of phosphorylation 27.2727 7 no
GO:0042326 negative regulation of phosphorylation 27.2727 8 no
GO:0043086 negative regulation of catalytic activity 27.2727 4 no
GO:0043549 regulation of kinase activity 27.2727 5 no
GO:0045859 regulation of protein kinase activity 27.2727 6 no
GO:0045936 negative regulation of phosphate metabolic process 27.2727 7 no
GO:0051174 regulation of phosphorus metabolic process 27.2727 5 no
GO:0051246 regulation of protein metabolic process 27.2727 5 no
GO:0051248 negative regulation of protein metabolic process 27.2727 6 no
GO:0051338 regulation of transferase activity 27.2727 4 no
GO:0051348 negative regulation of transferase activity 27.2727 5 no
GO:0031344 regulation of cell projection organization 27.2727 5 no
GO:0050807 regulation of synapse organization 27.2727 5 no
GO:0099175 regulation of postsynapse organization 27.2727 6 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 27.2727 6 no
GO:1902115 regulation of organelle assembly 27.2727 5 yes
GO:0022607 cellular component assembly 27.2727 4 no
GO:0034330 cell junction organization 27.2727 4 no
GO:0050808 synapse organization 27.2727 5 no
GO:0006796 phosphate-containing compound metabolic process 27.2727 4 no
GO:0001558 regulation of cell growth 27.2727 4 no
GO:0001932 regulation of protein phosphorylation 27.2727 7 no
GO:0051056 regulation of small GTPase mediated signal transduction 18.1818 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
GEPH_HUMAN [view entry] [view interactions] Low throughput yes yes
CDKL5_HUMAN [view entry] [view interactions] Low throughput yes yes
SMUF1_HUMAN [view interactions] Low throughput no yes
CDC42_HUMAN [view entry] [view interactions] Low throughput yes yes
GBRA2_HUMAN [view entry] [view interactions] Low throughput yes no
CPVL_HUMAN [view interactions] High throughput no no
CRML_HUMAN [view interactions] High throughput no yes
PSB5_HUMAN [view interactions] High throughput no yes
ARHG6_HUMAN [view interactions] High throughput no no
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
FANCL_HUMAN [view interactions] High throughput no yes
VEZF1_HUMAN [view interactions] High throughput no yes
TB22B_HUMAN [view interactions] High throughput no no
T10IP_HUMAN [view interactions] High throughput no no
F90A1_HUMAN [view interactions] High throughput no no
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
KAT5_HUMAN [view interactions] High throughput no yes
PKHA5_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
IHO1_HUMAN [view interactions] High throughput no no
BCL6_HUMAN [view interactions] High throughput no no
TFP11_HUMAN [view interactions] High throughput no no
HNRPL_HUMAN [view interactions] High throughput no yes
ARG28_HUMAN [view interactions] High throughput no yes
JUPI2_HUMAN [view interactions] High throughput no no
KALRN_HUMAN [view entry] [view interactions] High throughput yes yes
CCNT1_HUMAN [view interactions] High throughput no yes
MGAP_HUMAN [view interactions] High throughput no yes
NSRP1_HUMAN [view interactions] High throughput no yes
TPX2_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
KHDR1_HUMAN [view interactions] High throughput no yes
GBRA3_HUMAN [view entry] [view interactions] High throughput yes yes