Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ARHG9_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in ARHG9_HUMAN
GO:0019900 kinase binding 30.7692 4 no
GO:0019901 protein kinase binding 30.7692 5 no
GO:0003723 RNA binding 23.0769 4 no
GO:0046872 metal ion binding 23.0769 4 no
GO:0004890 GABA-A receptor activity 23.0769 5 no
GO:0005216 ion channel activity 23.0769 4 no
GO:0005230 extracellular ligand-gated ion channel activity 23.0769 6 no
GO:0005237 inhibitory extracellular ligand-gated ion channel activity 23.0769 7 no
GO:0005253 anion channel activity 23.0769 5 no
GO:0005254 chloride channel activity 23.0769 6 no
GO:0008503 benzodiazepine receptor activity 23.0769 4 no
GO:0008509 anion transmembrane transporter activity 23.0769 4 no
GO:0015103 inorganic anion transmembrane transporter activity 23.0769 4 no
GO:0015108 chloride transmembrane transporter activity 23.0769 5 no
GO:0015267 channel activity 23.0769 4 no
GO:0015276 ligand-gated ion channel activity 23.0769 5 no
GO:0016917 GABA receptor activity 23.0769 4 no
GO:0022824 transmitter-gated ion channel activity 23.0769 5 no
GO:0022834 ligand-gated channel activity 23.0769 6 no
GO:0022835 transmitter-gated channel activity 23.0769 4 no
GO:0022836 gated channel activity 23.0769 5 no
GO:0022851 GABA-gated chloride ion channel activity 23.0769 5 no
GO:0098960 postsynaptic neurotransmitter receptor activity 23.0769 4 no
GO:0099095 ligand-gated anion channel activity 23.0769 6 no
GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 23.0769 5 no
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential 23.0769 6 no
GO:0017076 purine nucleotide binding 23.0769 4 no
GO:0032555 purine ribonucleotide binding 23.0769 4 no
GO:0035639 purine ribonucleoside triphosphate binding 23.0769 4 no
GO:0005085 guanyl-nucleotide exchange factor activity 15.3846 5 yes
GO:0030695 GTPase regulator activity 15.3846 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ARHG9_HUMAN
GO:0008104 protein localization 46.1538 4 no
GO:0022607 cellular component assembly 46.1538 4 no
GO:0034330 cell junction organization 38.4615 4 no
GO:0050808 synapse organization 38.4615 5 no
GO:0009966 regulation of signal transduction 38.4615 4 yes
GO:0010646 regulation of cell communication 38.4615 4 yes
GO:0051174 regulation of phosphorus metabolic process 30.7692 5 no
GO:0051338 regulation of transferase activity 30.7692 4 no
GO:0060255 regulation of macromolecule metabolic process 30.7692 4 no
GO:0080090 regulation of primary metabolic process 30.7692 4 no
GO:0016192 vesicle-mediated transport 30.7692 4 no
GO:0007268 chemical synaptic transmission 30.7692 6 no
GO:0034329 cell junction assembly 30.7692 5 no
GO:0051932 synaptic transmission, GABAergic 30.7692 7 no
GO:0098916 anterograde trans-synaptic signaling 30.7692 5 no
GO:0099537 trans-synaptic signaling 30.7692 4 no
GO:0019220 regulation of phosphate metabolic process 30.7692 6 no
GO:0031323 regulation of cellular metabolic process 30.7692 4 no
GO:0042325 regulation of phosphorylation 30.7692 7 no
GO:0043549 regulation of kinase activity 30.7692 5 no
GO:0048522 positive regulation of cellular process 30.7692 4 no
GO:0048523 negative regulation of cellular process 30.7692 4 no
GO:0051128 regulation of cellular component organization 30.7692 4 no
GO:0051171 regulation of nitrogen compound metabolic process 30.7692 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 23.0769 5 no
GO:0051246 regulation of protein metabolic process 23.0769 5 no
GO:0051248 negative regulation of protein metabolic process 23.0769 6 no
GO:0051348 negative regulation of transferase activity 23.0769 5 no
GO:0032880 regulation of protein localization 23.0769 5 no
GO:0050807 regulation of synapse organization 23.0769 5 no
GO:0051049 regulation of transport 23.0769 4 no
GO:0051223 regulation of protein transport 23.0769 5 no
GO:0060341 regulation of cellular localization 23.0769 4 no
GO:0070201 regulation of establishment of protein localization 23.0769 6 no
GO:0006811 ion transport 23.0769 4 no
GO:0006820 anion transport 23.0769 5 no
GO:0006821 chloride transport 23.0769 7 no
GO:0007416 synapse assembly 23.0769 6 no
GO:0015698 inorganic anion transport 23.0769 6 no
GO:0060078 regulation of postsynaptic membrane potential 23.0769 4 no
GO:0071310 cellular response to organic substance 23.0769 4 no
GO:0098656 anion transmembrane transport 23.0769 4 no
GO:0098660 inorganic ion transmembrane transport 23.0769 4 no
GO:0098661 inorganic anion transmembrane transport 23.0769 5 no
GO:1902476 chloride transmembrane transport 23.0769 6 no
GO:1904862 inhibitory synapse assembly 23.0769 7 no
GO:0006796 phosphate-containing compound metabolic process 23.0769 4 no
GO:0036211 protein modification process 23.0769 4 no
GO:0043412 macromolecule modification 23.0769 4 no
GO:1902531 regulation of intracellular signal transduction 23.0769 5 yes
GO:0006886 intracellular protein transport 23.0769 4 no
GO:0006996 organelle organization 23.0769 4 no
GO:0015031 protein transport 23.0769 4 no
GO:0071702 organic substance transport 23.0769 4 no
GO:0071705 nitrogen compound transport 23.0769 4 no
GO:0001932 regulation of protein phosphorylation 23.0769 7 no
GO:0001933 negative regulation of protein phosphorylation 23.0769 8 no
GO:0006469 negative regulation of protein kinase activity 23.0769 7 no
GO:0008284 positive regulation of cell population proliferation 23.0769 5 no
GO:0009892 negative regulation of metabolic process 23.0769 4 no
GO:0009893 positive regulation of metabolic process 23.0769 4 no
GO:0010563 negative regulation of phosphorus metabolic process 23.0769 6 no
GO:0010604 positive regulation of macromolecule metabolic process 23.0769 5 no
GO:0010605 negative regulation of macromolecule metabolic process 23.0769 5 no
GO:0031324 negative regulation of cellular metabolic process 23.0769 5 no
GO:0031325 positive regulation of cellular metabolic process 23.0769 5 no
GO:0031399 regulation of protein modification process 23.0769 6 no
GO:0031400 negative regulation of protein modification process 23.0769 7 no
GO:0033673 negative regulation of kinase activity 23.0769 6 no
GO:0042127 regulation of cell population proliferation 23.0769 4 no
GO:0042326 negative regulation of phosphorylation 23.0769 8 no
GO:0043086 negative regulation of catalytic activity 23.0769 4 no
GO:0044087 regulation of cellular component biogenesis 23.0769 4 no
GO:0045859 regulation of protein kinase activity 23.0769 6 no
GO:0045936 negative regulation of phosphate metabolic process 23.0769 7 no
GO:0051172 negative regulation of nitrogen compound metabolic process 23.0769 5 no
GO:0051056 regulation of small GTPase mediated signal transduction 15.3846 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
GEPH_HUMAN [view entry] [view interactions] Low throughput yes yes
SMUF1_HUMAN [view interactions] Low throughput no yes
CDC42_HUMAN [view entry] [view interactions] Low throughput yes yes
GBRA2_HUMAN [view entry] [view interactions] Low throughput yes no
IMB1_HUMAN [view entry] [view interactions] High throughput yes yes
CRML_HUMAN [view interactions] High throughput no yes
PSB5_HUMAN [view interactions] High throughput no yes
CPVL_HUMAN [view interactions] High throughput no no
ARHG6_HUMAN [view interactions] High throughput no no
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
FANCL_HUMAN [view interactions] High throughput no yes
VEZF1_HUMAN [view interactions] High throughput no yes
TB22B_HUMAN [view interactions] High throughput no no
T10IP_HUMAN [view interactions] High throughput no no
F90A1_HUMAN [view interactions] High throughput no no
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
KAT5_HUMAN [view interactions] High throughput no yes
PKHA5_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
IHO1_HUMAN [view interactions] High throughput no no
BCL6_HUMAN [view interactions] High throughput no no
TFP11_HUMAN [view interactions] High throughput no no
HNRPL_HUMAN [view interactions] High throughput no yes
ARG28_HUMAN [view interactions] High throughput no yes
JUPI2_HUMAN [view interactions] High throughput no no
KALRN_HUMAN [view entry] [view interactions] High throughput yes yes
CCNT1_HUMAN [view interactions] High throughput no yes
MGAP_HUMAN [view interactions] High throughput no yes
NSRP1_HUMAN [view interactions] High throughput no yes
TPX2_HUMAN [view interactions] High throughput no yes
KHDR1_HUMAN [view interactions] High throughput no yes
GBRA3_HUMAN [view entry] [view interactions] High throughput yes yes
NLGN2_HUMAN [view entry] [view interactions] Computational yes yes
GBRG2_HUMAN [view entry] [view interactions] Computational yes no